For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_3729 | - | - | 100% (326) | UDP-galactose 4-epimerase |
M. thermoresistible (build 8) | TH_1114 | - | 3e-13 | 26.55% (339) | PROBABLE CHOLESTEROL DEHYDROGENASE |
M. thermoresistible (build 8) | TH_0330 | rfbB | 1e-11 | 24.91% (269) | dTDP-glucose 4,6-dehydratase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3658c | galE1 | 3e-28 | 33.44% (320) | UDP-glucose 4-epimerase GALE1 (galactowaldenase) |
M. gilvum PYR-GCK | Mflv_1401 | - | 1e-148 | 78.46% (325) | UDP-glucose 4-epimerase |
M. tuberculosis H37Rv | Rv3634c | galE1 | 3e-28 | 33.44% (320) | UDP-glucose 4-epimerase GALE1 (galactowaldenase) |
M. leprae Br4923 | MLBr_00204 | rmlB2 | 2e-27 | 32.49% (317) | putative sugar-nucleotide dehydratase |
M. abscessus ATCC 19977 | MAB_0503 | - | 9e-25 | 30.67% (313) | UDP-glucose 4-epimerase GalE1 |
M. marinum M | MMAR_5133 | galE1 | 8e-27 | 32.28% (316) | UDP-glucose 4-epimerase GalE1 |
M. avium 104 | MAV_0524 | - | 4e-28 | 34.18% (316) | nucleoside-diphosphate-sugar epimerase |
M. smegmatis MC2 155 | MSMEG_6142 | - | 7e-26 | 31.56% (320) | nucleoside-diphosphate-sugar epimerase |
M. ulcerans Agy99 | MUL_4210 | galE1 | 5e-27 | 32.28% (316) | UDP-glucose 4-epimerase GalE1 |
M. vanbaalenii PYR-1 | Mvan_5389 | - | 1e-140 | 77.78% (315) | UDP-glucose 4-epimerase |
CLUSTAL 2.0.9 multiple sequence alignment MLBr_00204|M.leprae_Br4923 MYGEPVRALVTGAAGFIGSTLVDRLLADGHTVVGLDNFATGHAANLEHLA MAV_0524|M.avium_104 -----MRALVTGAAGFIGSTLVDRLLADGHTVVGLDNFASGRASNLEHLV Mb3658c|M.bovis_AF2122/97 -----MRALVTGAAGFIGSTLVDRLLADGHSVVGLDNFATGRATNLEHLA Rv3634c|M.tuberculosis_H37Rv -----MRALVTGAAGFIGSTLVDRLLADGHSVVGLDNFATGRATNLEHLA MMAR_5133|M.marinum_M -----MRALVTGAAGFIGSTLVDRLLADGHTVVGLDNFATGRATNLEHLV MUL_4210|M.ulcerans_Agy99 -----MRALVTGAAGFIGSTLVDRLLADGHTVVGLDNFATGRATNLEHLV MAB_0503|M.abscessus_ATCC_1997 -----MRAMVTGAAGFIGSTLVDRLLADGHEVTGLDNLATGKVANLEAAE MSMEG_6142|M.smegmatis_MC2_155 ---MAVRTLVTGAAGFIGSTLVDRLLADGHGVVGLDDLSSGRAENLHSAE TH_3729|M.thermoresistible__bu -----MTWLVTGGAGYIGSHVVRALLEADLPVVVIDDLSTGLEKFVPSEV Mflv_1401|M.gilvum_PYR-GCK -----MSWLITGGAGYIGSHVARAMLEAGRDVVVIDDLSSGFESFVPDGA Mvan_5389|M.vanbaalenii_PYR-1 -----MTWLVTGGAGYIGSHVVRALRGADLDVVVIDDLSTGRAEFVPDGV : ::**.**:*** :. : . *. :*::::* : MLBr_00204|M.leprae_Br4923 STPALAFVEADIVTADLQTILDEHRPEVVFHLAAQIDVRHSVVDPQFDAS MAV_0524|M.avium_104 GNPAHVFVEADIVTADLEAILDEHRPEVVFHLAAQIDVRHSVADPQFDAS Mb3658c|M.bovis_AF2122/97 DNSAHVFVEADIVTADLHAILEQHRPEVVFHLAAQIDVRRSVADPQFDAA Rv3634c|M.tuberculosis_H37Rv DNSAHVFVEADIVTADLHAILEQHRPEVVFHLAAQIDVRRSVADPQFDAA MMAR_5133|M.marinum_M DNLAHVFVEADIVDADLQAIFEQHRPEVIFHLAAQIDVRHSVADPQFDAS MUL_4210|M.ulcerans_Agy99 DNLAHVFVEADIVDADLQAIFEQHRPEVIFHLAAQIDVRHSVADPQFDAS MAB_0503|M.abscessus_ATCC_1997 ANAKFTFVKDDIVEADLDAVVAEYSPEVIFHLAAQIDVRHSVADPQFDSS MSMEG_6142|M.smegmatis_MC2_155 NSDKFEFVKADIVDADLTGLLAEFKPEVIFHLAAQISVKRSVDDPPFDAT TH_3729|M.thermoresistible__bu PLVRGTLLDADLVAR----ALREHRVSGVIHIAGFKYAGVSVQQPLHTYE Mflv_1401|M.gilvum_PYR-GCK AFVEGTLLDAALVDD----TLARFDVDGVIHIAGYKYAGESVKRPLHTYE Mvan_5389|M.vanbaalenii_PYR-1 PLVRANLLDADAVRT----TLDAYGVSGVIHIAGYKYAGESVRRPLHTYQ ::. * . . . ::*:*. . ** * . MLBr_00204|M.leprae_Br4923 VNVIGTVRLAEAARHTGVRKIVHTSSGGSIYGTPSQYPTPETVPTDPTSP MAV_0524|M.avium_104 VNVIGTVRLAEAARRTGVRKIVHTSSGGSIYGTPPTYPTPETVPTDPASP Mb3658c|M.bovis_AF2122/97 VNVIGTVRLAEAARQTGVRKIVHTSSGGSIYGTPPEYPTPETAPTDPASP Rv3634c|M.tuberculosis_H37Rv VNVIGTVRLAEAARQTGVRKIVHTSSGGSIYGTPPEYPTPETAPTDPASP MMAR_5133|M.marinum_M VNVIGTLRLAEAARLTGVRKVVHTSSGGSIYGTPPQYPTSERVPTDPASP MUL_4210|M.ulcerans_Agy99 VNVIGTLRLAEAARLTGVRKVVHTSSGGSIYGTPPQYPTSERVPTDPASP MAB_0503|M.abscessus_ATCC_1997 VNVVGTVRLAEAARKAGVRKIVHTSSGGSIYGTPKQIPTSETVPTDPHSP MSMEG_6142|M.smegmatis_MC2_155 VNVVGTVRLAEAARLAGVRKVVHTSSGGSVYGTPPAYPTSEDMPVNPASP TH_3729|M.thermoresistible__bu QNVSAMVTLLKAMQDTGVDMMVFSSS-AATFGTPDVDLVTETTPTRPESP Mflv_1401|M.gilvum_PYR-GCK QNVSTTVILLQAMEARGVGQIVFSSS-AATFGTPDVDIVDESTPTTPESP Mvan_5389|M.vanbaalenii_PYR-1 QNVSAMVTLLDAMSDAGVDRIVFSSS-AATYGTPDTAVVDETTATRPESP ** : * .* ** :*.:** .: :*** . * .. * ** MLBr_00204|M.leprae_Br4923 YAAGKVAGEIYLNTFRHLCGLDCSHIAPANVYGPRQDPYGEAG---VVAI MAV_0524|M.avium_104 YAAGKVAGEIYLNTFRHLYGLDCSHIAPANVYGPRQDPHGEAG---VVAI Mb3658c|M.bovis_AF2122/97 YAAGKVAGEIYLNTFRHLYGLDCSHIAPANVYGPRQDPHGEAG---VVAI Rv3634c|M.tuberculosis_H37Rv YAAGKVAGEIYLNTFRHLYGLDCSHIAPANVYGPRQDPHGEAG---VVAI MMAR_5133|M.marinum_M YAAGKVAGEIYLNTFRHLYGLECSHIAPANVYGPRQDPHGEAG---VVAI MUL_4210|M.ulcerans_Agy99 YAAGKVAGEIYLNTFRHLYGLECSHIAPANVYGPRQDPHGEAG---VVAI MAB_0503|M.abscessus_ATCC_1997 YAAGKVAGEIYLNTFRHLYGLECSHIAPANVYGPRQDPHGEAG---VVAI MSMEG_6142|M.smegmatis_MC2_155 YAAGKVAGEVYLNMYRNLYDLDCSHIAPANVYGPRQDPHGEAG---VVAI TH_3729|M.thermoresistible__bu YGESKLIGEWLLADVGRATGLRHTSLRYFNVVGSGSPELFDVSPHNLFPL Mflv_1401|M.gilvum_PYR-GCK YGETKLIGEWLLRDAGRASGLRHTSLRYFNVVGSGAVELFDASPHNLFPL Mvan_5389|M.vanbaalenii_PYR-1 YGESKLIGEWLLRDIGVATGLRHTSLRYFNVVGSGPDGVFDVSPFNLFPK *. *: ** * .* : : ** *. :.. :.. MLBr_00204|M.leprae_Br4923 FVQALLSDRPTKVFGD------GTHTRDYVFVDDVVDAFIKASGDAGGGQ MAV_0524|M.avium_104 FAQALLSGKPTKVFGD------GTNTRDYVFVDDVVDAFVKASGDAGGGQ Mb3658c|M.bovis_AF2122/97 FAQALLSGKPTRVFGD------GTNTRDYVFVDDVVDAFVRVSADVGGGL Rv3634c|M.tuberculosis_H37Rv FAQALLSGKPTRVFGD------GTNTRDYVFVDDVVDAFVRVSADVGGGL MMAR_5133|M.marinum_M FAQALLSGKPTKVFGD------GTNTRDYVFVDDVVDAFVRAGSDVGGGQ MUL_4210|M.ulcerans_Agy99 FAQALLSGKPTKVFGD------GTNTRDYVFVDDVVDAFVKAGSDVGGGQ MAB_0503|M.abscessus_ATCC_1997 FAQALLSGRSTKVFGD------GGNTRDYVFVDDVVEAFVRASGPDGGGQ MSMEG_6142|M.smegmatis_MC2_155 FSEALLAGRTTKIFGD------GSDTRDYVFVDDVVDAFVRAGGPAGGGQ TH_3729|M.thermoresistible__bu VFDMLYRGETPRINGDDYPTPDGTCVRDYIHVADLALAHVAAARRLQAGE Mflv_1401|M.gilvum_PYR-GCK VFDMLFRGETPRINGDDYPTPDGTCVRDYIHVSDLALAHVAAAQRLAAGE Mvan_5389|M.vanbaalenii_PYR-1 VFDMLVHGQTPRINGDDYPTPDGTCVRDYIHVEDVAAAHVAAAHRLESGL . : * ....:: ** * .***:.* *:. *.: .. .* MLBr_00204|M.leprae_Br4923 ----RFNIGTGIETSDRQLHTAVSAAVGGPDDPEFHPPRLGDLKRSCLDI MAV_0524|M.avium_104 ----RFNIGTGVETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDI Mb3658c|M.bovis_AF2122/97 ----RFNIGTGKETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDI Rv3634c|M.tuberculosis_H37Rv ----RFNIGTGKETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDI MMAR_5133|M.marinum_M ----RFNIGTGVETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDI MUL_4210|M.ulcerans_Agy99 ----RFNIGTGVETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDI MAB_0503|M.abscessus_ATCC_1997 ----RFNVGTGVETSDRQLHSLVAAAAGAPDDPEFHPPRLGDLRQSCLDV MSMEG_6142|M.smegmatis_MC2_155 ----RFNVGTGVETSTRELHTAIAGAVGAPDEPEFHPPRLGDLRRSRLDN TH_3729|M.thermoresistible__bu PVEPVYNLGSGSGTSVREIMTAIRKVTGVDFVPEIAPRRPGDPARIVASG Mflv_1401|M.gilvum_PYR-GCK PVEPVYNLGSGAGTSVREIMTAMRTVTGVDFEPVVMPRRPGDPARIVAAG Mvan_5389|M.vanbaalenii_PYR-1 PIEPVYNLGSGSGTSVREIMTTMRAVTGVDFEPDVAARRAGDPARIVAAG :*:*:* ** *:: : : ..* * . . * ** : MLBr_00204|M.leprae_Br4923 GLATTVLGWSPQVQLDDGVRRTVEYFRAAQRS---- MAV_0524|M.avium_104 GLAARVLGWQPKVGLQQGVARTVEYFRNQHN----- Mb3658c|M.bovis_AF2122/97 GLAERVLGWRPQIELADGVRRTVEYFRHKHTD---- Rv3634c|M.tuberculosis_H37Rv GLAERVLGWRPQIELADGVRRTVEYFRHKHTD---- MMAR_5133|M.marinum_M SRAEEVLGWRPQVELADGVRRTVDYFRRTHGS---- MUL_4210|M.ulcerans_Agy99 SRAEEVLGWRPQVELADGVRRTVDYFRRTHGS---- MAB_0503|M.abscessus_ATCC_1997 GLAKRVLGWEPRVPLADGIRRTVDFFRS-------- MSMEG_6142|M.smegmatis_MC2_155 TRAREVLGWQPQVALAEGIAKTVEFFRNKSQ----- TH_3729|M.thermoresistible__bu ELAARDLGWRMRHTLEDMVKSAWEAR-QRAGDAYPR Mflv_1401|M.gilvum_PYR-GCK DLAARDLGWSNRHSLEEMVASAWRAR-QHAGDAYPR Mvan_5389|M.vanbaalenii_PYR-1 DLAARDLDWRMRHSLTDMVASAWSALPSRATDEAAP * *.* : * : : :