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MPDEISYHTAGRLETLAVAARHCCSNDMPFVEHPRGRAYYRHWPAPEPRAAVIFLHGFGEHTGLYHRYGF TLNAAGIDLWVVDQFGHGLTPGTRGDFGKIEDSSALAEALTVLAEKQNPGLPLIAQGHSFGSVVTLFRLL AEPDRYRAGIISGAPLVPIPDMLDADTSLDLDLNWLSSDPFYRDSLENDPLAFSDADAAPLTRELDRAWD RFGLELPQLTVPTLAVHGSADVIAPVDAVRAYAEQIEPLQLKEFHGARHDVLNESVHREVAATVVKFISS QIG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6029 | - | - | 100% (283) | hypothetical protein MSMEG_6029 |
| M. smegmatis MC2 155 | MSMEG_0220 | - | 6e-22 | 27.94% (272) | monoglyceride lipase |
| M. smegmatis MC2 155 | MSMEG_4719 | - | 2e-06 | 25.82% (244) | peptidase S9, prolyl oligopeptidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0189 | - | 1e-25 | 28.79% (264) | lysophospholipase |
| M. gilvum PYR-GCK | Mflv_1469 | - | 1e-108 | 71.37% (255) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv0183 | - | 1e-25 | 28.79% (264) | lysophospholipase |
| M. leprae Br4923 | MLBr_02603 | - | 6e-24 | 29.17% (264) | hypothetical protein MLBr_02603 |
| M. abscessus ATCC 19977 | MAB_4551c | - | 2e-20 | 28.74% (261) | lysophospholipase |
| M. marinum M | MMAR_0427 | - | 7e-26 | 28.74% (261) | lysophospholipase |
| M. avium 104 | MAV_4997 | - | 1e-25 | 29.92% (264) | lysophospholipase |
| M. thermoresistible (build 8) | TH_0447 | lipV | 8e-08 | 27.75% (209) | POSSIBLE LIPASE LIPV |
| M. ulcerans Agy99 | MUL_1077 | - | 5e-26 | 28.74% (261) | lysophospholipase |
| M. vanbaalenii PYR-1 | Mvan_5302 | - | 1e-111 | 76.10% (251) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1469|M.gilvum_PYR-GCK ---------------------------MPFLDHDRGPAYYRHWAAE-DPR
Mvan_5302|M.vanbaalenii_PYR-1 ---------------------------MPFLGHERGRAYYRHWAAA-EPA
MSMEG_6029|M.smegmatis_MC2_155 MPDEISYHTAGRLETLAVAARHCCSNDMPFVEHPRGRAYYRHWPAP-EPR
Mb0189|M.bovis_AF2122/97 --------------------MTTTRTERNFAGIGDVRIVYDVWTPDTAPQ
Rv0183|M.tuberculosis_H37Rv --------------------MTTTRTERNFAGIGDVRIVYDVWTPDTAPQ
MMAR_0427|M.marinum_M --------------------MNTTRTERTFDGVGGVHIVYDVWTPDAAPK
MUL_1077|M.ulcerans_Agy99 --------------------MNTTRTERTFDGVGGVHIVYDVWTPDAAPK
MAV_4997|M.avium_104 --------------------MN--RTERSFDGVGGVRIVYDVWTPEVAPR
MLBr_02603|M.leprae_Br4923 --------------------MTITRTERNFYGVGGVRIVYDVWMPDTRPR
MAB_4551c|M.abscessus_ATCC_199 -------------------------MQRTFDGADDVRIVYDTWTPAGTPR
TH_0447|M.thermoresistible__bu --------------------------------------VYRYGPAG---P
* .
Mflv_1469|M.gilvum_PYR-GCK AAVVFLHGFGEHTGLYHRYAFALNAAGIDVWAVDQFGHGLSPGTRGDFGS
Mvan_5302|M.vanbaalenii_PYR-1 AAVVFLHGFGEHTGLYHRYGFALNAAGIDLWAVDQFGHGLSPGDRGDFGT
MSMEG_6029|M.smegmatis_MC2_155 AAVIFLHGFGEHTGLYHRYGFTLNAAGIDLWVVDQFGHGLTPGTRGDFGK
Mb0189|M.bovis_AF2122/97 AVVVLAHGLGEHARRYDHVAQRLGAAGLVTYALDHRGHGRSGGKRVLVRD
Rv0183|M.tuberculosis_H37Rv AVVVLAHGLGEHARRYDHVAQRLGAAGLVTYALDHRGHGRSGGKRVLVRD
MMAR_0427|M.marinum_M AVVVLAHGLGEHARRYDHVAQRLGAAGLVTYALDHRGHGRSGGKRVLVRD
MUL_1077|M.ulcerans_Agy99 AVVVLAHGLGEHARRYDHVAQRLGAAGLVTYTLDHRGHGRSGGKRVLVRD
MAV_4997|M.avium_104 AVLVLAHGFGEHARRYDHVARRFGAAGLVTYALDHRGHGRSGGKRVLVRD
MLBr_02603|M.leprae_Br4923 AVIILAHGFGEHARRYDHVAHYFAAAGLATYALDLRGHGRSAGKRVLVRD
MAB_4551c|M.abscessus_ATCC_199 AVVVLSHGFGEHARRYDHVARRFNEAGYLVYALDHRGHGRSGGKRVYLRD
TH_0447|M.thermoresistible__bu PRLLAIHGLTGHGRRWQTLATRH-LPEIAVAAPDLIGHGRSS-----WAA
. :: **: * :. . . . * *** :
Mflv_1469|M.gilvum_PYR-GCK IEDSSALADALTERASTRS--VPLIAQGHSFGSIVTLFRLLDGPNRYRAA
Mvan_5302|M.vanbaalenii_PYR-1 IEDSSALAEQLTDLVAQQHPGLPLIAQGHSFGAIVTLFRLLDGAARYRAA
MSMEG_6029|M.smegmatis_MC2_155 IEDSSALAEALTVLAEKQNPGLPLIAQGHSFGSVVTLFRLLAEPDRYRAG
Mb0189|M.bovis_AF2122/97 ISEYTADFDTLVGIATREYPGCKRIVLGHSMGGGIVFAYGVERPDNYDLM
Rv0183|M.tuberculosis_H37Rv ISEYTADFDTLVGIATREYPGCKRIVLGHSMGGGIVFAYGVERPDNYDLM
MMAR_0427|M.marinum_M ISEYTADFDTLVGIATRDNPGLKCIVLGHSMGGGIVFAYGVERPDNYDLM
MUL_1077|M.ulcerans_Agy99 ISEYTADFDTLVGIATRDNPGLKCIVLGHSMGGGIVFAYGVERPDNYDLM
MAV_4997|M.avium_104 IHEYTTDFDTLVGIATREHHGLKCIVVGHSMGGGIVFAYGVERPDNYDLM
MLBr_02603|M.leprae_Br4923 LSEYNADFDILVGIATRDHPGLKRIVAGHSMGGAIVFAYGVERPDNYDLM
MAB_4551c|M.abscessus_ATCC_199 ISEYTDDFGTLVDIAAREHPDLKRIVLGHSMGGGIVFAYGVDHQDRYDLM
TH_0447|M.thermoresistible__bu PWTFEANVGALVALL-EDQADGPVVVVGHSFGGAVAMHLAAARPDLVAGL
*. :. ***:*. :.:
Mflv_1469|M.gilvum_PYR-GCK VISGSPLIP--------------VPELVDA--DTSIDLDPGWLSSDPFYL
Mvan_5302|M.vanbaalenii_PYR-1 VVSGAPLIP--------------IPDLLDA--DTSFDLDPAWLSADPFYV
MSMEG_6029|M.smegmatis_MC2_155 IISGAPLVP--------------IPDMLDA--DTSLDLDLNWLSSDPFYR
Mb0189|M.bovis_AF2122/97 VLSAPAVAAQDLVSPVVAVAAKLLGVVVPG--LPVQELDFTAISRDPEVV
Rv0183|M.tuberculosis_H37Rv VLSAPAVAAQDLVSPVVAVAAKLLGVVVPG--LPVQELDFTAISRDPEVV
MMAR_0427|M.marinum_M VLSAPAVAAQDLVSPVIAAAAKVLGVVVPG--LPVQELDFTAISRDPEVV
MUL_1077|M.ulcerans_Agy99 VLSAPAVAAQDLVSPVIAAAAKVLGVVVPG--LPVQELDFTAISRDPEVV
MAV_4997|M.avium_104 VLSGPAVAAQDQVSPLLALAAKVLGVIVPG--LPAQELDADAVSRDPEVV
MLBr_02603|M.leprae_Br4923 VLSGPAVAAQDMVSPLRAVVGKGLGLVAPG--LPVHQLEVDAISRNRAVV
MAB_4551c|M.abscessus_ATCC_199 VLSGPAIAAQVGLPYVLTLVAPVVGRLAPG--LPVQKLDVNAISHDPAII
TH_0447|M.thermoresistible__bu VLLDPAIGLDGEWMREIAESMLASPDYPDREEARTEKFTGSWADVEPAEL
:: ..: .: . :
Mflv_1469|M.gilvum_PYR-GCK DALENDPLAFVESDSTALTRELDRGWDRFGSDLPALSVPTLAVHGVNDPI
Mvan_5302|M.vanbaalenii_PYR-1 DSLENDPLAFVASDSTALTRELDRGWDRFGTDLPSLSVPTLAVHGVNDPI
MSMEG_6029|M.smegmatis_MC2_155 DSLENDPLAFSDADAAPLTRELDRAWDRFGLELPQLTVPTLAVHGSADVI
Mb0189|M.bovis_AF2122/97 QAYNTDPLVHHGRVPAGIGRALLQVGETMPRRAPALTAPLLVLHGTDDRL
Rv0183|M.tuberculosis_H37Rv QAYNTDPLVHHGRVPAGIGRALLQVGETMPRRAPALTAPLLVLHGTDDRL
MMAR_0427|M.marinum_M AAYQNDPQVYHGRVPAGIGRALLQVGETMPRRAPALTAPLLVIHGTDDRL
MUL_1077|M.ulcerans_Agy99 AAYQNDPQVYHGRVPAGIGRALLQVGETMPRRAPALTAPLLVIHGTDDRL
MAV_4997|M.avium_104 AAYRNDPLVYHGKVPAGVGRALLQVGETMPQRAPALTAPLLVVHGSDDRL
MLBr_02603|M.leprae_Br4923 AAYKDDPLVYHGKVPAGVGRVMLQVGETMTRRAPVLTTPLLVVHGSEDRL
MAB_4551c|M.abscessus_ATCC_199 AAYHADPLVHHGRVPAGIGRALLGVGKTMRQRAAGLKRPVLTMHGSDDRL
TH_0447|M.thermoresistible__bu DRDLDEHLIALPGGRFGWRICVPAMMAYWSELARDVVLPPSGIPTTLVRA
: : : * :
Mflv_1469|M.gilvum_PYR-GCK APIGAVRAYAEQI--DALELAAFDGARHDVLNESQHGDVAAAIIGFIESH
Mvan_5302|M.vanbaalenii_PYR-1 APIGAVRAYAEQI--EALQLVEFAGARHDVLNEVQHRDVAAAIIDFIHRS
MSMEG_6029|M.smegmatis_MC2_155 APVDAVRAYAEQI--EPLQLKEFHGARHDVLNESVHREVAATVVKFISSQ
Mb0189|M.bovis_AF2122/97 IPIEGSRRLVECVGSADVQLKEYPGLYHEVFNEPERNQVLDDVVAWLTER
Rv0183|M.tuberculosis_H37Rv IPIEGSRRLVECVGSADVQLKEYPGLYHEVFNEPERNQVLDDVVAWLTER
MMAR_0427|M.marinum_M IPIEGSRRLVGHVGSADVELKEYPGLYHEAFNEPERDQVLDDVVSWITAR
MUL_1077|M.ulcerans_Agy99 IPIEGSRRLVGHVGSADVELKEYPGPYHEAFNEPERDQVLDDVVSWITAR
MAV_4997|M.avium_104 IPVAGSRRLVECVGSADVELKVYPGLYHEVFNEPEREQVLDDVVGWITAR
MLBr_02603|M.leprae_Br4923 VLVDGSHRLVECVGSTDVELKVYPGLYHEVFNEPERDQVLEDVVCWILKR
MAB_4551c|M.abscessus_ATCC_199 TAPEGSRWLSESA--PDATLKIWNGLYHEIFNEFEKELVLDEVVGWIDAR
TH_0447|M.thermoresistible__bu AWTDPPYVTGELLDGLSQRLGADLTLVDLDCLHMVAQAKPAETAELIRRH
* . . :
Mflv_1469|M.gilvum_PYR-GCK LR
Mvan_5302|M.vanbaalenii_PYR-1 Y-
MSMEG_6029|M.smegmatis_MC2_155 IG
Mb0189|M.bovis_AF2122/97 L-
Rv0183|M.tuberculosis_H37Rv L-
MMAR_0427|M.marinum_M L-
MUL_1077|M.ulcerans_Agy99 L-
MAV_4997|M.avium_104 L-
MLBr_02603|M.leprae_Br4923 L-
MAB_4551c|M.abscessus_ATCC_199 L-
TH_0447|M.thermoresistible__bu LG