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M. ulcerans Agy99 MUL_1077 (-)

annotation: lysophospholipase
coordinates: 1137963 - 1138802
length: 279

MNTTRTERTFDGVGGVHIVYDVWTPDAAPKAVVVLAHGLGEHARRYDHVAQRLGAAGLVTYTLDHRGHGR
SGGKRVLVRDISEYTADFDTLVGIATRDNPGLKCIVLGHSMGGGIVFAYGVERPDNYDLMVLSAPAVAAQ
DLVSPVIAAAAKVLGVVVPGLPVQELDFTAISRDPEVVAAYQNDPQVYHGRVPAGIGRALLQVGETMPRR
APALTAPLLVIHGTDDRLIPIEGSRRLVGHVGSADVELKEYPGPYHEAFNEPERDQVLDDVVSWITARL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1077--100% (279)lysophospholipase
M. ulcerans Agy99MUL_3358-1e-0721.40% (257) hydrolase
M. ulcerans Agy99MUL_1035-2e-0726.15% (283) hypothetical protein MUL_1035

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0189-1e-14288.89% (279) lysophospholipase
M. gilvum PYR-GCKMflv_0518-1e-10866.67% (276) acylglycerol lipase
M. tuberculosis H37RvRv0183-1e-14288.89% (279) lysophospholipase
M. leprae Br4923MLBr_02603-1e-11973.84% (279) hypothetical protein MLBr_02603
M. abscessus ATCC 19977MAB_4551c-1e-9564.10% (273) lysophospholipase
M. marinum MMMAR_0427-1e-16099.28% (279) lysophospholipase
M. avium 104MAV_4997-1e-13784.73% (275) lysophospholipase
M. smegmatis MC2 155MSMEG_0220-1e-10767.38% (279) monoglyceride lipase
M. thermoresistible (build 8)TH_0684hpx2e-1026.71% (277) POSSIBLE NON-HEME HALOPEROXIDASE HPX
M. vanbaalenii PYR-1Mvan_0150-1e-11469.53% (279) alpha/beta hydrolase fold

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0518|M.gilvum_PYR-GCK          ----MTHSERSFDGLGGVRIVYDVWTPESDSRGVVVLAHGYAEHARRYDH
Mvan_0150|M.vanbaalenii_PYR-1       --MAVTRTERSFDGVGGVRIVYDVWTPETPPRGIVVLAHGYAEHARRYDH
MSMEG_0220|M.smegmatis_MC2_155      -MVSSTRSEHSFAGVGGVRIVYDVWTPDTDPRGVVVLAHGYAEHAGRYHH
MUL_1077|M.ulcerans_Agy99           --MNTTRTERTFDGVGGVHIVYDVWTPDAAPKAVVVLAHGLGEHARRYDH
MMAR_0427|M.marinum_M               --MNTTRTERTFDGVGGVHIVYDVWTPDAAPKAVVVLAHGLGEHARRYDH
Mb0189|M.bovis_AF2122/97            --MTTTRTERNFAGIGDVRIVYDVWTPDTAPQAVVVLAHGLGEHARRYDH
Rv0183|M.tuberculosis_H37Rv         --MTTTRTERNFAGIGDVRIVYDVWTPDTAPQAVVVLAHGLGEHARRYDH
MAV_4997|M.avium_104                --MN--RTERSFDGVGGVRIVYDVWTPEVAPRAVLVLAHGFGEHARRYDH
MLBr_02603|M.leprae_Br4923          --MTITRTERNFYGVGGVRIVYDVWMPDTRPRAVIILAHGFGEHARRYDH
MAB_4551c|M.abscessus_ATCC_199      -------MQRTFDGADDVRIVYDTWTPAGTPRAVVVLSHGFGEHARRYDH
TH_0684|M.thermoresistible__bu      VEQMPPGRVVSVTAPDGVRLHAEVFGPADAPP--IVLAHGITCAIRVWAH
                                              .. . ..*::  :.: *   .   ::*:**       : *

Mflv_0518|M.gilvum_PYR-GCK          VAARFAESGLITYALDHRGHGRSGG-KRVYLRDITEYTGDFHTLVGIARN
Mvan_0150|M.vanbaalenii_PYR-1       VAARFAEAGLGIYALDHRGHGRSGG-KRVYVRDISEYTGDFHSLVRIAAG
MSMEG_0220|M.smegmatis_MC2_155      VAQRFGAAGLLVYALDHRGHGRSGG-KRVHLRDLSEFVEDFRTLVGIAAN
MUL_1077|M.ulcerans_Agy99           VAQRLGAAGLVTYTLDHRGHGRSGG-KRVLVRDISEYTADFDTLVGIATR
MMAR_0427|M.marinum_M               VAQRLGAAGLVTYALDHRGHGRSGG-KRVLVRDISEYTADFDTLVGIATR
Mb0189|M.bovis_AF2122/97            VAQRLGAAGLVTYALDHRGHGRSGG-KRVLVRDISEYTADFDTLVGIATR
Rv0183|M.tuberculosis_H37Rv         VAQRLGAAGLVTYALDHRGHGRSGG-KRVLVRDISEYTADFDTLVGIATR
MAV_4997|M.avium_104                VARRFGAAGLVTYALDHRGHGRSGG-KRVLVRDIHEYTTDFDTLVGIATR
MLBr_02603|M.leprae_Br4923          VAHYFAAAGLATYALDLRGHGRSAG-KRVLVRDLSEYNADFDILVGIATR
MAB_4551c|M.abscessus_ATCC_199      VARRFNEAGYLVYALDHRGHGRSGG-KRVYLRDISEYTDDFGTLVDIAAR
TH_0684|M.thermoresistible__bu      QIAELADD-YRVIAFDHRGHGRSSVPRRRWQYSLDHLASDLDAVLDATLD
                                        :        ::* ******.  :*    .: .   *:  ::  :  

Mflv_0518|M.gilvum_PYR-GCK          AYPHLKLIVLGHSMGGGVVFTYGVEHPD--------------DYDAMVLS
Mvan_0150|M.vanbaalenii_PYR-1       EHPGRKLVVLGHSMGGGVVFTYGVEHPD--------------DYDAMVLS
MSMEG_0220|M.smegmatis_MC2_155      DHPTLPRIVLGHSMGGGIVFAYGARYPG--------------EYSAMVLS
MUL_1077|M.ulcerans_Agy99           DNPGLKCIVLGHSMGGGIVFAYGVERPD--------------NYDLMVLS
MMAR_0427|M.marinum_M               DNPGLKCIVLGHSMGGGIVFAYGVERPD--------------NYDLMVLS
Mb0189|M.bovis_AF2122/97            EYPGCKRIVLGHSMGGGIVFAYGVERPD--------------NYDLMVLS
Rv0183|M.tuberculosis_H37Rv         EYPGCKRIVLGHSMGGGIVFAYGVERPD--------------NYDLMVLS
MAV_4997|M.avium_104                EHHGLKCIVVGHSMGGGIVFAYGVERPD--------------NYDLMVLS
MLBr_02603|M.leprae_Br4923          DHPGLKRIVAGHSMGGAIVFAYGVERPD--------------NYDLMVLS
MAB_4551c|M.abscessus_ATCC_199      EHPDLKRIVLGHSMGGGIVFAYGVDHQD--------------RYDLMVLS
TH_0684|M.thermoresistible__bu      --PGERAVIAGHSMGGIAISSWAERYPERVSERAAAVALINTTTGDLLHN
                                           :: ******  : ::.                     . :: .

Mflv_0518|M.gilvum_PYR-GCK          GPAVNAHDSVPAVKLVMAKVLGRIAPGLPVENLPADAVSRDPQVVSDYEN
Mvan_0150|M.vanbaalenii_PYR-1       GPAVDAHSSVSPVMVLLAKVLGRLSPGLPVENLPADAVSRDPQVVAAYEN
MSMEG_0220|M.smegmatis_MC2_155      GPAVNAHDGVSPVLVAVAKVLGKLAPGIPVENLDADAVSRDPEVVAAYKA
MUL_1077|M.ulcerans_Agy99           APAVAAQDLVSPVIAAAAKVLGVVVPGLPVQELDFTAISRDPEVVAAYQN
MMAR_0427|M.marinum_M               APAVAAQDLVSPVIAAAAKVLGVVVPGLPVQELDFTAISRDPEVVAAYQN
Mb0189|M.bovis_AF2122/97            APAVAAQDLVSPVVAVAAKLLGVVVPGLPVQELDFTAISRDPEVVQAYNT
Rv0183|M.tuberculosis_H37Rv         APAVAAQDLVSPVVAVAAKLLGVVVPGLPVQELDFTAISRDPEVVQAYNT
MAV_4997|M.avium_104                GPAVAAQDQVSPLLALAAKVLGVIVPGLPAQELDADAVSRDPEVVAAYRN
MLBr_02603|M.leprae_Br4923          GPAVAAQDMVSPLRAVVGKGLGLVAPGLPVHQLEVDAISRNRAVVAAYKD
MAB_4551c|M.abscessus_ATCC_199      GPAIAAQVGLPYVLTLVAPVVGRLAPGLPVQKLDVNAISHDPAIIAAYHA
TH_0684|M.thermoresistible__bu      VQLLPVPDRFAAVRVRTASAVIKTVAGMPARLAAVPSRYVVSMMAVGRDA
                                       : .   .. :    .  :    .*:*..     :      :      

Mflv_0518|M.gilvum_PYR-GCK          DPLVH----------HGKLPAGVGRALIAVGETMPARAAAITAPLLVVHG
Mvan_0150|M.vanbaalenii_PYR-1       DPLVH----------HGKLPAGVGRALIGVGETMPARAAAITAPLLIVHG
MSMEG_0220|M.smegmatis_MC2_155      DPMVH----------HGKLPAGIARALIGLGQSMPQRAAALTAPLLVVHG
MUL_1077|M.ulcerans_Agy99           DPQVY----------HGRVPAGIGRALLQVGETMPRRAPALTAPLLVIHG
MMAR_0427|M.marinum_M               DPQVY----------HGRVPAGIGRALLQVGETMPRRAPALTAPLLVIHG
Mb0189|M.bovis_AF2122/97            DPLVH----------HGRVPAGIGRALLQVGETMPRRAPALTAPLLVLHG
Rv0183|M.tuberculosis_H37Rv         DPLVH----------HGRVPAGIGRALLQVGETMPRRAPALTAPLLVLHG
MAV_4997|M.avium_104                DPLVY----------HGKVPAGVGRALLQVGETMPQRAPALTAPLLVVHG
MLBr_02603|M.leprae_Br4923          DPLVY----------HGKVPAGVGRVMLQVGETMTRRAPVLTTPLLVVHG
MAB_4551c|M.abscessus_ATCC_199      DPLVH----------HGRVPAGIGRALLGVGKTMRQRAAGLKRPVLTMHG
TH_0684|M.thermoresistible__bu      DPAITNFVHELFTETPPAARDGWARTLVDAMGPRHIGLHNLTVPTLVIGS
                                    ** :                 * .*.::    .       :. * * : .

Mflv_0518|M.gilvum_PYR-GCK          DKDRLIPVAGSRQLMECIGSPDAHLKVYPGLYHEVFNEPEKELVLDDVTS
Mvan_0150|M.vanbaalenii_PYR-1       DNDKLIPVEGSRKLVDRVGSADVHLKEYPGLYHEVFNEPEKALVLDDVTS
MSMEG_0220|M.smegmatis_MC2_155      DKDRLIPVAGSRLLVDRVASEDVHLKVYPGLYHEVFNEPEQKLVLDDVTS
MUL_1077|M.ulcerans_Agy99           TDDRLIPIEGSRRLVGHVGSADVELKEYPGPYHEAFNEPERDQVLDDVVS
MMAR_0427|M.marinum_M               TDDRLIPIEGSRRLVGHVGSADVELKEYPGLYHEAFNEPERDQVLDDVVS
Mb0189|M.bovis_AF2122/97            TDDRLIPIEGSRRLVECVGSADVQLKEYPGLYHEVFNEPERNQVLDDVVA
Rv0183|M.tuberculosis_H37Rv         TDDRLIPIEGSRRLVECVGSADVQLKEYPGLYHEVFNEPERNQVLDDVVA
MAV_4997|M.avium_104                SDDRLIPVAGSRRLVECVGSADVELKVYPGLYHEVFNEPEREQVLDDVVG
MLBr_02603|M.leprae_Br4923          SEDRLVLVDGSHRLVECVGSTDVELKVYPGLYHEVFNEPERDQVLEDVVC
MAB_4551c|M.abscessus_ATCC_199      SDDRLTAPEGSRWLSESAP--DATLKIWNGLYHEIFNEFEKELVLDEVVG
TH_0684|M.thermoresistible__bu      DRDRLLPLVSSRRIAEAAPN-LFDFVELPGGHCAILECPDRVNDHLRALA
                                      *:*    .*: :          :    * :   ::  ::      .  

Mflv_0518|M.gilvum_PYR-GCK          WIESKL-----
Mvan_0150|M.vanbaalenii_PYR-1       WIESQL-----
MSMEG_0220|M.smegmatis_MC2_155      WIVSHL-----
MUL_1077|M.ulcerans_Agy99           WITARL-----
MMAR_0427|M.marinum_M               WITARL-----
Mb0189|M.bovis_AF2122/97            WLTERL-----
Rv0183|M.tuberculosis_H37Rv         WLTERL-----
MAV_4997|M.avium_104                WITARL-----
MLBr_02603|M.leprae_Br4923          WILKRL-----
MAB_4551c|M.abscessus_ATCC_199      WIDARL-----
TH_0684|M.thermoresistible__bu      AAAADARRATS