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MPFLGHERGRAYYRHWAAAEPAAAVVFLHGFGEHTGLYHRYGFALNAAGIDLWAVDQFGHGLSPGDRGDF GTIEDSSALAEQLTDLVAQQHPGLPLIAQGHSFGAIVTLFRLLDGAARYRAAVVSGAPLIPIPDLLDADT SFDLDPAWLSADPFYVDSLENDPLAFVASDSTALTRELDRGWDRFGTDLPSLSVPTLAVHGVNDPIAPIG AVRAYAEQIEALQLVEFAGARHDVLNEVQHRDVAAAIIDFIHRSY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5302 | - | - | 100% (255) | alpha/beta hydrolase fold |
| M. vanbaalenii PYR-1 | Mvan_0150 | - | 2e-19 | 28.86% (246) | alpha/beta hydrolase fold |
| M. vanbaalenii PYR-1 | Mvan_0723 | - | 1e-04 | 38.71% (62) | hypothetical protein Mvan_0723 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0189 | - | 4e-22 | 28.09% (267) | lysophospholipase |
| M. gilvum PYR-GCK | Mflv_1469 | - | 1e-120 | 81.67% (251) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv0183 | - | 4e-22 | 28.09% (267) | lysophospholipase |
| M. leprae Br4923 | MLBr_02603 | - | 5e-18 | 24.72% (267) | hypothetical protein MLBr_02603 |
| M. abscessus ATCC 19977 | MAB_4551c | - | 2e-18 | 28.03% (264) | lysophospholipase |
| M. marinum M | MMAR_0427 | - | 9e-22 | 28.00% (250) | lysophospholipase |
| M. avium 104 | MAV_4997 | - | 7e-22 | 27.41% (259) | lysophospholipase |
| M. smegmatis MC2 155 | MSMEG_6029 | - | 1e-111 | 76.10% (251) | hypothetical protein MSMEG_6029 |
| M. thermoresistible (build 8) | TH_3979 | - | 4e-06 | 28.31% (219) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1077 | - | 2e-21 | 27.60% (250) | lysophospholipase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5302|M.vanbaalenii_PYR-1 ---------------------------MPFLGHERGRAYYRHWAAA-EPA
Mflv_1469|M.gilvum_PYR-GCK ---------------------------MPFLDHDRGPAYYRHWAAE-DPR
MSMEG_6029|M.smegmatis_MC2_155 MPDEISYHTAGRLETLAVAARHCCSNDMPFVEHPRGRAYYRHWPAP-EPR
Mb0189|M.bovis_AF2122/97 --------------------MTTTRTERNFAGIGDVRIVYDVWTPDTAPQ
Rv0183|M.tuberculosis_H37Rv --------------------MTTTRTERNFAGIGDVRIVYDVWTPDTAPQ
MMAR_0427|M.marinum_M --------------------MNTTRTERTFDGVGGVHIVYDVWTPDAAPK
MUL_1077|M.ulcerans_Agy99 --------------------MNTTRTERTFDGVGGVHIVYDVWTPDAAPK
MAV_4997|M.avium_104 --------------------MN--RTERSFDGVGGVRIVYDVWTPEVAPR
MLBr_02603|M.leprae_Br4923 --------------------MTITRTERNFYGVGGVRIVYDVWMPDTRPR
MAB_4551c|M.abscessus_ATCC_199 -------------------------MQRTFDGADDVRIVYDTWTPAGTPR
TH_3979|M.thermoresistible__bu --------------------MAEVTVDPAVTFDSSGCRLAGTLVSPAGPR
. . *
Mvan_5302|M.vanbaalenii_PYR-1 AAVVFLHGFGEHTGLYHR----------YGFALNAAGIDLWAVDQFGHGL
Mflv_1469|M.gilvum_PYR-GCK AAVVFLHGFGEHTGLYHR----------YAFALNAAGIDVWAVDQFGHGL
MSMEG_6029|M.smegmatis_MC2_155 AAVIFLHGFGEHTGLYHR----------YGFTLNAAGIDLWVVDQFGHGL
Mb0189|M.bovis_AF2122/97 AVVVLAHGLGEHARRYDH----------VAQRLGAAGLVTYALDHRGHGR
Rv0183|M.tuberculosis_H37Rv AVVVLAHGLGEHARRYDH----------VAQRLGAAGLVTYALDHRGHGR
MMAR_0427|M.marinum_M AVVVLAHGLGEHARRYDH----------VAQRLGAAGLVTYALDHRGHGR
MUL_1077|M.ulcerans_Agy99 AVVVLAHGLGEHARRYDH----------VAQRLGAAGLVTYTLDHRGHGR
MAV_4997|M.avium_104 AVLVLAHGFGEHARRYDH----------VARRFGAAGLVTYALDHRGHGR
MLBr_02603|M.leprae_Br4923 AVIILAHGFGEHARRYDH----------VAHYFAAAGLATYALDLRGHGR
MAB_4551c|M.abscessus_ATCC_199 AVVVLSHGFGEHARRYDH----------VARRFNEAGYLVYALDHRGHGR
TH_3979|M.thermoresistible__bu AAALLLSGSGRVDRDSDTRGLRLGVTRILADELARARVATLRYDKRGVGA
*. :: * *. . . : * * * *
Mvan_5302|M.vanbaalenii_PYR-1 SPGDRGDFGTIEDSSALAEQLTDLVAQQHPGLPLIAQGHSFGAIVTLFRL
Mflv_1469|M.gilvum_PYR-GCK SPGTRGDFGSIEDSSALADALTERASTRS--VPLIAQGHSFGSIVTLFRL
MSMEG_6029|M.smegmatis_MC2_155 TPGTRGDFGKIEDSSALAEALTVLAEKQNPGLPLIAQGHSFGSVVTLFRL
Mb0189|M.bovis_AF2122/97 SGGKRVLVRDISEYTADFDTLVGIATREYPGCKRIVLGHSMGGGIVFAYG
Rv0183|M.tuberculosis_H37Rv SGGKRVLVRDISEYTADFDTLVGIATREYPGCKRIVLGHSMGGGIVFAYG
MMAR_0427|M.marinum_M SGGKRVLVRDISEYTADFDTLVGIATRDNPGLKCIVLGHSMGGGIVFAYG
MUL_1077|M.ulcerans_Agy99 SGGKRVLVRDISEYTADFDTLVGIATRDNPGLKCIVLGHSMGGGIVFAYG
MAV_4997|M.avium_104 SGGKRVLVRDIHEYTTDFDTLVGIATREHHGLKCIVVGHSMGGGIVFAYG
MLBr_02603|M.leprae_Br4923 SAGKRVLVRDLSEYNADFDILVGIATRDHPGLKRIVAGHSMGGAIVFAYG
MAB_4551c|M.abscessus_ATCC_199 SGGKRVYLRDISEYTDDFGTLVDIAAREHPDLKRIVLGHSMGGGIVFAYG
TH_3979|M.thermoresistible__bu SGGDYLRAG-FHEQLADARAALRRLTERMPGLPVLVVGHSEGGLHAIELA
: * : : :. *** *. .:
Mvan_5302|M.vanbaalenii_PYR-1 LDGAARYRAAVVSGAPLIP--------------IPDLLDADTSFDLDPAW
Mflv_1469|M.gilvum_PYR-GCK LDGPNRYRAAVISGSPLIP--------------VPELVDADTSIDLDPGW
MSMEG_6029|M.smegmatis_MC2_155 LAEPDRYRAGIISGAPLVP--------------IPDMLDADTSLDLDLNW
Mb0189|M.bovis_AF2122/97 VERPDNYDLMVLSAPAVAAQDLVSPVVAVAAKLLGVVVPGLPVQELDFTA
Rv0183|M.tuberculosis_H37Rv VERPDNYDLMVLSAPAVAAQDLVSPVVAVAAKLLGVVVPGLPVQELDFTA
MMAR_0427|M.marinum_M VERPDNYDLMVLSAPAVAAQDLVSPVIAAAAKVLGVVVPGLPVQELDFTA
MUL_1077|M.ulcerans_Agy99 VERPDNYDLMVLSAPAVAAQDLVSPVIAAAAKVLGVVVPGLPVQELDFTA
MAV_4997|M.avium_104 VERPDNYDLMVLSGPAVAAQDQVSPLLALAAKVLGVIVPGLPAQELDADA
MLBr_02603|M.leprae_Br4923 VERPDNYDLMVLSGPAVAAQDMVSPLRAVVGKGLGLVAPGLPVHQLEVDA
MAB_4551c|M.abscessus_ATCC_199 VDHQDRYDLMVLSGPAIAAQVGLPYVLTLVAPVVGRLAPGLPVQKLDVNA
TH_3979|M.thermoresistible__bu ADSAVAAAVLLGTPARPGAEVLRWQAEQILDTMPRWARALLRAVRLDPLE
: : . . *:
Mvan_5302|M.vanbaalenii_PYR-1 LSADPFYVDSLENDPLAFVASDSTALTRELDRGWDRFGTDLPSLSVPTLA
Mflv_1469|M.gilvum_PYR-GCK LSSDPFYLDALENDPLAFVESDSTALTRELDRGWDRFGSDLPALSVPTLA
MSMEG_6029|M.smegmatis_MC2_155 LSSDPFYRDSLENDPLAFSDADAAPLTRELDRAWDRFGLELPQLTVPTLA
Mb0189|M.bovis_AF2122/97 ISRDPEVVQAYNTDPLVHHGRVPAGIGRALLQVGETMPRRAPALTAPLLV
Rv0183|M.tuberculosis_H37Rv ISRDPEVVQAYNTDPLVHHGRVPAGIGRALLQVGETMPRRAPALTAPLLV
MMAR_0427|M.marinum_M ISRDPEVVAAYQNDPQVYHGRVPAGIGRALLQVGETMPRRAPALTAPLLV
MUL_1077|M.ulcerans_Agy99 ISRDPEVVAAYQNDPQVYHGRVPAGIGRALLQVGETMPRRAPALTAPLLV
MAV_4997|M.avium_104 VSRDPEVVAAYRNDPLVYHGKVPAGVGRALLQVGETMPQRAPALTAPLLV
MLBr_02603|M.leprae_Br4923 ISRNRAVVAAYKDDPLVYHGKVPAGVGRVMLQVGETMTRRAPVLTTPLLV
MAB_4551c|M.abscessus_ATCC_199 ISHDPAIIAAYHADPLVHHGRVPAGIGRALLGVGKTMRQRAAGLKRPVLT
TH_3979|M.thermoresistible__bu TQRRRLARIAASSRDVMRIQGVRVNARWLRELIAHDPRPALRRITVPVLA
. : . . :. * *.
Mvan_5302|M.vanbaalenii_PYR-1 VHGVNDPIAPIGAVRAYAEQI--EALQLVEFAGARHDVLNEVQHR-----
Mflv_1469|M.gilvum_PYR-GCK VHGVNDPIAPIGAVRAYAEQI--DALELAAFDGARHDVLNESQHG-----
MSMEG_6029|M.smegmatis_MC2_155 VHGSADVIAPVDAVRAYAEQI--EPLQLKEFHGARHDVLNESVHR-----
Mb0189|M.bovis_AF2122/97 LHGTDDRLIPIEGSRRLVECVGSADVQLKEYPGLYHEVFNEPERN-----
Rv0183|M.tuberculosis_H37Rv LHGTDDRLIPIEGSRRLVECVGSADVQLKEYPGLYHEVFNEPERN-----
MMAR_0427|M.marinum_M IHGTDDRLIPIEGSRRLVGHVGSADVELKEYPGLYHEAFNEPERD-----
MUL_1077|M.ulcerans_Agy99 IHGTDDRLIPIEGSRRLVGHVGSADVELKEYPGPYHEAFNEPERD-----
MAV_4997|M.avium_104 VHGSDDRLIPVAGSRRLVECVGSADVELKVYPGLYHEVFNEPERE-----
MLBr_02603|M.leprae_Br4923 VHGSEDRLVLVDGSHRLVECVGSTDVELKVYPGLYHEVFNEPERD-----
MAB_4551c|M.abscessus_ATCC_199 MHGSDDRLTAPEGSRWLSESA--PDATLKIWNGLYHEIFNEFEKE-----
TH_3979|M.thermoresistible__bu ITGAHDVQVPPADIDMMRELIP-GPFEGHVVAGVNHLLRPDPHRRGPRGY
: * * * * : :
Mvan_5302|M.vanbaalenii_PYR-1 ----------DVAAAIIDFIHRSY---
Mflv_1469|M.gilvum_PYR-GCK ----------DVAAAIIGFIESHLR--
MSMEG_6029|M.smegmatis_MC2_155 ----------EVAATVVKFISSQIG--
Mb0189|M.bovis_AF2122/97 ----------QVLDDVVAWLTERL---
Rv0183|M.tuberculosis_H37Rv ----------QVLDDVVAWLTERL---
MMAR_0427|M.marinum_M ----------QVLDDVVSWITARL---
MUL_1077|M.ulcerans_Agy99 ----------QVLDDVVSWITARL---
MAV_4997|M.avium_104 ----------QVLDDVVGWITARL---
MLBr_02603|M.leprae_Br4923 ----------QVLEDVVCWILKRL---
MAB_4551c|M.abscessus_ATCC_199 ----------LVLDEVVGWIDARL---
TH_3979|M.thermoresistible__bu RRSARDPLAPAVLELITDWVSRTVPVP
* : ::