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MRIGLSGGAANVDDIVRQAQRAEEDGFSSLWYASGVAGDPLTAMAIAGRATTSIELGTAVLQTYPCHPLL QANRVAAAANAMGRPGLTLGLGPSHEPVVRGVLGLSYDRPGTNAEEYLRIVSALLRGETVDHDGREWTAH SDGRMVAVDHRVPILLSALSPRMLRIAGTFADGVVLWMASAEAIRSHIVPKLTVAATAAGRPAPRVVAGL PVVVHDDPVAARAAVDAASTSYASMTNYRRIIEAGGGSAAGDVAVSGDETAVQTKLRELLDAGATDIWAQ PVAVGTDRAERVASLRRTRALLRELARA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0528 | - | - | 100% (308) | hypothetical protein MSMEG_0528 |
| M. smegmatis MC2 155 | MSMEG_4879 | - | 2e-51 | 37.11% (318) | hypothetical protein MSMEG_4879 |
| M. smegmatis MC2 155 | MSMEG_5732 | - | 1e-36 | 31.72% (290) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3120c | - | 1e-13 | 28.09% (299) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1261 | - | 1e-114 | 67.43% (307) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3093c | - | 2e-13 | 28.09% (299) | oxidoreductase |
| M. leprae Br4923 | MLBr_00269 | - | 6e-09 | 26.11% (203) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1339 | - | 2e-40 | 34.78% (299) | putative monooxygenase (luciferase-like) |
| M. marinum M | MMAR_4796 | - | 7e-46 | 37.72% (289) | oxidoreductase |
| M. avium 104 | MAV_0923 | - | 7e-54 | 41.88% (320) | hypothetical protein MAV_0923 |
| M. thermoresistible (build 8) | TH_4355 | - | 3e-51 | 37.22% (317) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_0365 | - | 1e-45 | 37.37% (289) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_4259 | - | 5e-52 | 38.16% (304) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3120c|M.bovis_AF2122/97 ----MTDIEVALPFWLD-----RPDHEATDVALAAADTGFAALWIGEMAT
Rv3093c|M.tuberculosis_H37Rv ----MTDIEVALPFWLD-----RPDHEATDVALAAADTGFAALWIGEMAT
MSMEG_0528|M.smegmatis_MC2_155 ---MRIGLSGG----------AANVDDIVRQAQRAEEDGFSSLWYASGVA
Mflv_1261|M.gilvum_PYR-GCK ---MRIGLTGG----------GSSVDKIVAQAQQAEADGFAALWYASAVA
MMAR_4796|M.marinum_M ---MRVGVMIGPERGDS----GRKVGRMLADIDWAETAGLDSAWIPQIPN
MUL_0365|M.ulcerans_Agy99 ---MRVGVMIGPERGDS----GRKVGRMLADIDWAETAGLDSAWIPQIPN
TH_4355|M.thermoresistible__bu ---MRVGVMIGAERGDM----ARKVRKFLEDIEWAESAGFDTAWMPQVPN
Mvan_4259|M.vanbaalenii_PYR-1 ---MKLGVMIGAERGDM----ARKVGKLVSDIEWAESAGLDTAWMPQVPN
MAV_0923|M.avium_104 ---MRIGLMVGSDKERSR---AERLAGLVDDAAAAERGGFTAFWMPQVPG
MAB_1339|M.abscessus_ATCC_1997 ---MKLGVAIGRPLSVQNS--TNLVDTFIAHARRVAEAGVRTLWLGQMYH
MLBr_00269|M.leprae_Br4923 MAELRLGYKASAEQFAPRELVELGVAAEAHGMDSATVSDHFQPWRHQGGH
. . . . * .
Mb3120c|M.bovis_AF2122/97 Y-DAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLA-LGVSSVASLTGCR
Rv3093c|M.tuberculosis_H37Rv Y-DAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLA-LGVSSVASLTGCR
MSMEG_0528|M.smegmatis_MC2_155 G-DPLTAMAIAGRATTSIELGTAVLQTYPCHPLLQANRVAAAANAMGRPG
Mflv_1261|M.gilvum_PYR-GCK G-DPLVAMAFAGRATSTIELGTAVLQTYPCHPLLQANRVAAAANAMGRPG
MMAR_4796|M.marinum_M DFDALVAVTLMGTRSSRIELGTAVVPLQTQHPIALA-RQALSVHAATGGR
MUL_0365|M.ulcerans_Agy99 DFDALVAVTLMGTRSSRIELGTAVVPLQTQHPIALA-RQALSVHAATGGR
TH_4355|M.thermoresistible__bu DFDALTMVALMATRTDRIELGTAVVPLQAQHPIALA-RQALSVHAGSGGR
Mvan_4259|M.vanbaalenii_PYR-1 DFDCLTMVALMAAHTSRIELGTAVVPLQAQHPIALA-RQALSVHAMAQGR
MAV_0923|M.avium_104 YLDALTAVALIGQATERIEIGTAVVPIQTRHPMALA-QQALTTQVACGGR
MAB_1339|M.abscessus_ATCC_1997 Y-DSITMAAVVGQTVPDVTVGVSVIPINPRHPIEVS-AAAQTAQAATHGR
MLBr_00269|M.leprae_Br4923 ASFSLSWMTAVGERTNRILLGTSVLTPTFRYNPAVIGQAFATMGCLYPNR
: : . : : .. : :
Mb3120c|M.bovis_AF2122/97 VDLALGA--SSPAIVAGWHGRP--WAHHVPVMRETIECLRSIFTG-ARVE
Rv3093c|M.tuberculosis_H37Rv VDLALGA--SSPAIVAGWHGRP--WAHHVPVMRETIECLRSIFTG-ARVE
MSMEG_0528|M.smegmatis_MC2_155 LTLGLGP--SHEPVVRGVLGLS--YDRPGTNAEEYLRIVSALLRG-ETVD
Mflv_1261|M.gilvum_PYR-GCK LTLGLGP--SHEPIVRNVLGLN--YDHPVRNTREYVQIVTGLLAG-ADID
MMAR_4796|M.marinum_M LVLGVGP--SHHWIVDDMLGLP--YQRPAAYTRDYLEVLAAALANPGPVD
MUL_0365|M.ulcerans_Agy99 LVLGVGP--SHHWIVDDMLGLP--YQRPAAYTRDYLEVLAAALANPGPVD
TH_4355|M.thermoresistible__bu LALGVGP--SHHWIIRDMLGIP--YERPAAYTRDYLEVLNAAIAGPGPVD
Mvan_4259|M.vanbaalenii_PYR-1 LALGVGP--SHHWIVRDMLGLP--YEKPAAYTRDYLEVLNAALAGPGDVD
MAV_0923|M.avium_104 FTLGIGP--SHHWIVNGQLGLP--YERPARLTRNYLQVLGAAFAGPGSVD
MAB_1339|M.abscessus_ATCC_1997 FQLGLGL--GAPVIEGPSYGLH--VDKPIRRLREYLITLRQLLDA-GTAD
MLBr_00269|M.leprae_Br4923 VFLGVGTGEALNEVATGYQGAWPEFKERFARLRESVRLMRELWRG-DRVD
. *.:* . : * . .: : : :
Mb3120c|M.bovis_AF2122/97 YSGRHVNSRG-FRLRG-AAPDTRIALGAFGPGMIRLAAQHADEVVLNLAS
Rv3093c|M.tuberculosis_H37Rv YSGRHVNSRG-FRLRG-AAPDTRIALGAFGPGMIRLAAQHADEVVLNLAS
MSMEG_0528|M.smegmatis_MC2_155 HDGREWTAHSDGRMVA-VDHRVPILLSALSPRMLRIAGTFADGVVLWMAS
Mflv_1261|M.gilvum_PYR-GCK LDGTDWTAHSAGRMTA-LDHPVPVLLSALSPRMLRVATKFTDGVVLWLAT
MMAR_4796|M.marinum_M VENDSFRVHNPLDLA--AVAPLPVLVAALGPVMLTLAGERADGTVLWMAD
MUL_0365|M.ulcerans_Agy99 VENDSFRVHNPLDLA--AVAPLPVLVAALGPVMLTLAGERADGTVLWMAD
TH_4355|M.thermoresistible__bu VENDSFTVHNPTVLGT-DDTPMPVLVAALGPVMLQIAGELADGTVLWMAD
Mvan_4259|M.vanbaalenii_PYR-1 VENDTFTVHNPTVLG--AEQPLPVLVAALGPVMLQIAGERADGTVLWMAD
MAV_0923|M.avium_104 VDNESYCVHSPVDVT--DSFGVSILLSALGPTMLQLAGERADGTILWMAD
MAB_1339|M.abscessus_ATCC_1997 FHGQTLTVAPQFTTSQPGGENIPVLVAAMAPQALRATGELADGTIPLHAG
MLBr_00269|M.leprae_Br4923 FDGDYYQLKGASIYDV-PEGGVPIYIAAGGPEVAKYAGRAGEGFVCTSGK
. : :.* .* : : : .
Mb3120c|M.bovis_AF2122/97 -PFRVG-RVRAAIDSAAAAAGRAAPRLTVWVPVAVNPGAAAHSQLAAQLA
Rv3093c|M.tuberculosis_H37Rv -PFRVG-RVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLA
MSMEG_0528|M.smegmatis_MC2_155 -AEAIRSHIVPKLTVAATAAGRPAPRVVAGLPVVVH--DDPVAARAA---
Mflv_1261|M.gilvum_PYR-GCK -ATAIAERIAP-----AVAGG----RIVAGLPVAVH--DDIREAREA---
MMAR_4796|M.marinum_M -ERAVAEHVVPRISKAADNAGRPAPRIVAGIPVCLCGSSEVEVARDR---
MUL_0365|M.ulcerans_Agy99 -ERAVAEHVVPRISKAADNAGRPVPRIVAGIPVCLCGSSEVEVARDR---
TH_4355|M.thermoresistible__bu -ERAIGEHIAPRITKAADNAGRPAPRIIAGIPVCLCANSEIEVAKER---
Mvan_4259|M.vanbaalenii_PYR-1 -EKAIGGHIAPKINKAAAEAGRPAPRIVAGIPVCLCANSEIDAAKDR---
MAV_0923|M.avium_104 -ERAIGEHVVPRITAAAGGAGRPAPRVVAGVPVAVCSNSEIDDARAY---
MAB_1339|M.abscessus_ATCC_1997 -PRALGQEVVPVISAAAERAGRPRPRVIAGVAVVVTSEPERVRALAI---
MLBr_00269|M.leprae_Br4923 GEELYTEKLIPAVLEGAAVAGRDADDIDKMIEIKMSYDPDPEQALSNIRF
.: . * .* : : : :
Mb3120c|M.bovis_AF2122/97 VYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGS
Rv3093c|M.tuberculosis_H37Rv VYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGS
MSMEG_0528|M.smegmatis_MC2_155 ---VDAASTSYASMTNYRRIIEAGGGSAAG-------------DVAVSGD
Mflv_1261|M.gilvum_PYR-GCK ---IAATAGGYERMSNYQNIIRAGGGASAA-------------DVGIVGD
MMAR_4796|M.marinum_M ---ANRILGEAEVSPNYQRLLGYGDAKDVG-------------DICAAGD
MUL_0365|M.ulcerans_Agy99 ---ANRILGEAEVSPNYQRLLGHGDAKDVG-------------DICAAGD
TH_4355|M.thermoresistible__bu ---ANRILGEAEVSPNYQRLLERGDARDVG-------------DLCAAGD
Mvan_4259|M.vanbaalenii_PYR-1 ---ANRILAEAETSPNYQKLLDRGDARSVG-------------DLCAAGD
MAV_0923|M.avium_104 ---AGEMLGHAEFSPNYVRLLQHGDAEDVG-------------DTMAAGD
MAB_1339|M.abscessus_ATCC_1997 -----EDMAFYENIPSYRKVLDAEGVQHTG-------------ELAIIGD
MLBr_00269|M.leprae_Br4923 WAPLSLAAEQKHSIDDPIEMEKVADALPIEQVAK---------RWIVVSD
. : ..
Mb3120c|M.bovis_AF2122/97 PDRVAARLRAYADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDN
Rv3093c|M.tuberculosis_H37Rv PDRVAARLRAYADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDN
MSMEG_0528|M.smegmatis_MC2_155 ETAVQTKLRELLDAGATDIWAQPVAVGTDRAERVASLRRTRALLRELARA
Mflv_1261|M.gilvum_PYR-GCK EAAVTRQLVELIEAGATDVWAQPVAVGADRAQRSASVKRTRALLAALARE
MMAR_4796|M.marinum_M EDAILARFRRFAEAGVTDLSVRLLPIGDNREELVASKRRTRDMIATLATE
MUL_0365|M.ulcerans_Agy99 EDAILARFRRFAEAGVTDLSVRLLPIGDNREELVASKRRTRDMIATLATE
TH_4355|M.thermoresistible__bu EEAIMARFRRFADAGVTDLSVRLLPIGETRDELVASKYRTREVIAQLAAD
Mvan_4259|M.vanbaalenii_PYR-1 EDAILARFKQFADAGVTDLSVRLLPIGETRDELVASKYRTREVIGELAKA
MAV_0923|M.avium_104 ESAVLRRLRRYRDAGATDLAARIVPLGNDARERAESRRRTHEFLSAVCPA
MAB_1339|M.abscessus_ATCC_1997 EQHVATELQRYFDAGATEVFASHTELGGPQD-----EARTLALLGELSRG
MLBr_00269|M.leprae_Br4923 PDEAVARVGQYVTWGLNHLVFHAPGHN-QRRFLELFEKDLAPRLRRLG--
.. * :
Mb3120c|M.bovis_AF2122/97 DGRR
Rv3093c|M.tuberculosis_H37Rv DGRR
MSMEG_0528|M.smegmatis_MC2_155 ----
Mflv_1261|M.gilvum_PYR-GCK G---
MMAR_4796|M.marinum_M VR--
MUL_0365|M.ulcerans_Agy99 VR--
TH_4355|M.thermoresistible__bu LR--
Mvan_4259|M.vanbaalenii_PYR-1 VR--
MAV_0923|M.avium_104 L---
MAB_1339|M.abscessus_ATCC_1997 N---
MLBr_00269|M.leprae_Br4923 ----