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KVNLGTGAQNSRDWERVLAEDWSRPPATPDHQCVQAALALGDLAEPLGFDGIWFPEHHGTPYGMTPNPIQ ALTYFAGRTERVSLGTFVAVVPWWNPIRLATQIAYLDIVSNGRYTTIGLGRGVSKGEFAAVGVPREESRQ RFNETLDILKLAFSGERFSYEGEIFSFPEMSLRPEPISTDLYDRIYSSSSTAESLEILSRRGMVPLFVGN KPITDAGEEVKKVNTFRAEEGLPPCQPKNVMFMYCTNSQDEIEQTEEWIWTANRDVNVHYGFADASNFRG VKGYEAYAAREASATAVLASEVGNQKKGGPPGYHASNLLIGSPETVYEKLKAAQEACSFSEVTIVPQFGT MPYEEAMESVKLFAAEVLPAVHDMPAPLHPSVLPESVTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5626 | - | - | 100% (390) | luciferase |
| M. smegmatis MC2 155 | MSMEG_4820 | - | 1e-17 | 30.43% (184) | hypothetical protein MSMEG_4820 |
| M. smegmatis MC2 155 | MSMEG_4863 | - | 2e-16 | 25.97% (385) | hypothetical protein MSMEG_4863 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1971 | - | 6e-11 | 22.46% (374) | monooxygenase |
| M. gilvum PYR-GCK | Mflv_4097 | - | 2e-14 | 32.17% (143) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3618 | - | 7e-11 | 22.62% (336) | monooxygenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3792 | - | 8e-16 | 30.61% (196) | luciferase-like protein |
| M. marinum M | MMAR_0308 | - | 0.0 | 79.90% (393) | monooxygenase |
| M. avium 104 | MAV_0881 | - | 1e-16 | 25.92% (355) | hypothetical protein MAV_0881 |
| M. thermoresistible (build 8) | TH_3517 | - | 9e-26 | 25.07% (355) | PUTATIVE putative luciferase |
| M. ulcerans Agy99 | MUL_4814 | - | 0.0 | 79.64% (393) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_5167 | - | 4e-15 | 34.75% (141) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0308|M.marinum_M ----MKVNIGLGAHN-----SLDWERVLAEDYDRPPSTADWECVQATLAL
MUL_4814|M.ulcerans_Agy99 ----MKVNIGLGAHN-----SLDWERVLAEDYDRPPSTADWECVQATLAL
MSMEG_5626|M.smegmatis_MC2_155 ----MKVNLGTGAQN-----SRDWERVLAEDWSRPPATPDHQCVQAALAL
MAB_3792|M.abscessus_ATCC_1997 ----MRFSISIPQFD-----TGSFDGDGVRDYLAR---------------
MAV_0881|M.avium_104 ----MKISLFYEFAL-----PRPWAPDDEHVLLQEC-----------LDE
Mflv_4097|M.gilvum_PYR-GCK ----MQFAITHPMHS-----HPYNPELVTGAGIAR--------------V
Mvan_5167|M.vanbaalenii_PYR-1 ----MRLVFALPHMLRLPAMSQPWEASVTGADQTR--------------M
Mb1971|M.bovis_AF2122/97 ----MEIGIFLMPAH-----PPERTLYDATRWDLD--------------V
Rv3618|M.tuberculosis_H37Rv MKAPLRFGVFITPFH-----PTGQSPTVALQYDMER--------------
TH_3517|M.thermoresistible__bu ----LRFGVFILGDK-----PNHLSHAQVLANVLEE--------------
:.. .
MMAR_0308|M.marinum_M GDLAEPLGFDGIWLPEHCG-TPYGMTPN------PIQALSYFAGRTERVN
MUL_4814|M.ulcerans_Agy99 GDLAEPLGFDGIWLPEHCG-TPYGMTPN------PIQALSYFAGRTERVN
MSMEG_5626|M.smegmatis_MC2_155 GDLAEPLGFDGIWFPEHHG-TPYGMTPN------PIQALTYFAGRTERVS
MAB_3792|M.abscessus_ATCC_1997 ---AEELGFAGGWTLEQTV-GSSPIIA-------PLELLAYAAACTTRLR
MAV_0881|M.avium_104 VEAADKAGFSTVWLTEHHFLEEYCHSTA------PEIFLAAASQRTENIR
Mflv_4097|M.gilvum_PYR-GCK AVAAEKAGFGGFGFTDHPAPTQRWLEAGGHDALDPFVAMGFAAAHTTTLR
Mvan_5167|M.vanbaalenii_PYR-1 ARCADQWGYDMIAVPEHFVIPAEHVELSGPHYLQSTVAQAYLAGATERIR
Mb1971|M.bovis_AF2122/97 IELADQLGYVEAWVGEHFTVPWEPICAP-------DLLLAQALLRTQQIK
Rv3618|M.tuberculosis_H37Rv VVALDRLGYDEAWFGEHHSGGYELIACP-------EVFIAAAAERTTHIR
TH_3517|M.thermoresistible__bu AQWAEEFGYDEIWLAEHHFSPYGTLADLP-------LVAAAIAAKTERIR
: *: :: * :
MMAR_0308|M.marinum_M LGTFVAVAP--WWHPIRLAHQMAYLDIISNGRYTTLGIGRGVSKGEFAAV
MUL_4814|M.ulcerans_Agy99 LGTFVAVAP--WWHPIRLAHQMAYLDIISNGRYTTLGIGRGVSKGEFAAV
MSMEG_5626|M.smegmatis_MC2_155 LGTFVAVVP--WWNPIRLATQIAYLDIVSNGRYTTIGLGRGVSKGEFAAV
MAB_3792|M.abscessus_ATCC_1997 LGVAVLVAS--QHDPLQLAAAVTAVDRLSHGR-LDVGVAPGGGARNFAAF
MAV_0881|M.avium_104 LGFGIMHLPPAVNHPARVAERIATLDLLSNGR-VEFGTGESSSVGELGGF
Mflv_4097|M.gilvum_PYR-GCK LIPNIVVLP--YRNPFVVAKAGATLDLISDGR-FTLAVGVGYLKREFAAL
Mvan_5167|M.vanbaalenii_PYR-1 LNSCITVLP--LQHPVVLAKALATADWMSGGR-MMVTFGVGWLQGEFEAL
Mb1971|M.bovis_AF2122/97 LAPGAHLLP--YHHPVELAHRVAYFDHLAQGR-FMLGVGASGIPGDWALY
Rv3618|M.tuberculosis_H37Rv LGTGVVSLP--YHHPLMVADRWVLLDHLTRGR-VMFGTGPGALPSDAYMM
TH_3517|M.thermoresistible__bu IGTACMVAP--FHDPIQLAERIALVDNLSGGR-FDAGFGRGYQAHEFKGF
: . .* :* . * :: ** . . :
MMAR_0308|M.marinum_M GVPRE--ESRQRFNETLDILALAFSGK---RFAYEGEIFTVPEMS-----
MUL_4814|M.ulcerans_Agy99 GVPRE--ESRQRFNETLDTLALAFSGK---RFAYEGEIFTVPEMS-----
MSMEG_5626|M.smegmatis_MC2_155 GVPRE--ESRQRFNETLDILKLAFSGE---RFSYEGEIFSFPEMS-----
MAB_3792|M.abscessus_ATCC_1997 GVDKQ--TFIARFTEGLDLMKLAWSDEE--RITFRGRFRDVADLA-----
MAV_0881|M.avium_104 NIDPA--DKRAQWEEALEVAIRCMVEEP--FSGFHGEHVQMPARN-----
Mflv_4097|M.gilvum_PYR-GCK GVEFD--ERAAVFEEALDVITQIWTTD---DLSYDGRNFSAKGIT-----
Mvan_5167|M.vanbaalenii_PYR-1 GVPFR--ERGRMADEYLAVIKELWTSD---APSFEGKYVSFREVA-----
Mb1971|M.bovis_AF2122/97 DVDGKNGEHREMTREALEIMLRIWTEDE--PWEHRGKYWNANGIAPMFEG
Rv3618|M.tuberculosis_H37Rv GIDPV--EQRRMMQESLEAILALFRAAPDERIDRHSDWFTLREAQ-----
TH_3517|M.thermoresistible__bu GIPMD--EATARYQECVEIVDLLLTQEN---VTYEGKFWQLHDVT-----
.: * : .
MMAR_0308|M.marinum_M ---LRPEPFSSDLFARIYSSSSTAESLEILA---RRGMVPLFVGNKPIED
MUL_4814|M.ulcerans_Agy99 ---LRPEPFSSDLFARIYSSSSTAESLEILA---RRGMVPLFVGNKPIED
MSMEG_5626|M.smegmatis_MC2_155 ---LRPEPISTDLYDRIYSSSSTAESLEILS---RRGMVPLFVGNKPITD
MAB_3792|M.abscessus_ATCC_1997 ---FQPKPVQR-PHPPIWFGGHAPAALARAV---RFGDAFLGAGSSTTAA
MAV_0881|M.avium_104 ---VIPKPLQK-PHPPVWVACTRPASVQMAA---QKAIGALSFAYTGPGP
Mflv_4097|M.gilvum_PYR-GCK ---AHPKPLTT-PHPPIWVGGNTSAARARVA---KYAQGWCPFRAPAMLA
Mvan_5167|M.vanbaalenii_PYR-1 ---FEPKPVQK-PHLPIWIGGDADAALRRAA---KYASGWWSFLTPP-EK
Mb1971|M.bovis_AF2122/97 LMRRHIKPYQK-PHPPIGVTGFSAGSETLKL---AGERGYIPMSLDLNTE
Rv3618|M.tuberculosis_H37Rv ---LHIRPYTW-PYPEIATAAMISPSGPRLAGALGTSLLSLSMSVPGGYA
TH_3517|M.thermoresistible__bu ---VHPRPVQN-PIPVWGTVMKTPSSFEWLA---DKGFGAIIGNPYQVDP
.* :
MMAR_0308|M.marinum_M AGREVQQVNTFRQEEGLPPCQPKN-------VMFMYCTASAEQAAESEEW
MUL_4814|M.ulcerans_Agy99 AGREVQQVNTFRQEEGLPPCQPKN-------VMFMYCTASAEQAAESEEW
MSMEG_5626|M.smegmatis_MC2_155 AGEEVKKVNTFRAEEGLPPCQPKN-------VMFMYCTNSQDEIEQTEEW
MAB_3792|M.abscessus_ATCC_1997 FAEEVTTIHRELAIQGKDPARFTI-------GKRVYLMIDDD--------
MAV_0881|M.avium_104 LTERVNGYYKEFEENGVPVTPAINPNILAIGGDLSMMVAKTDEEALQRLG
Mflv_4097|M.gilvum_PYR-GCK QTARTAALETT---------------------------------------
Mvan_5167|M.vanbaalenii_PYR-1 LAERLDFIKSQPDYDGRP--------------------------------
Mb1971|M.bovis_AF2122/97 YVATHWDAVEEGALRSGRTPDRRD-------WRLVREVLVAETDEQAFRY
Rv3618|M.tuberculosis_H37Rv ALETAWGVVREQAAKAGRGEPDRAD------WRVLSIMHLSDSRDQAIDD
TH_3517|M.thermoresistible__bu DLQGALDLYLETQAKKGLEAATGN-----VWALLNAFCHQDDAFARSYPR
MMAR_0308|M.marinum_M IWTANRDVTVHYGFADASNFKGVKGYEAYAAREASATAVLASSVTGDAKG
MUL_4814|M.ulcerans_Agy99 IWTANRDVTVHYGFADASNFKGVKGYEAYAAREASATAVLASSVTGDAKG
MSMEG_5626|M.smegmatis_MC2_155 IWTANRDVNVHYGFADASNFRGVKGYEAYAAREASATAVLASEVGNQKKG
MAB_3792|M.abscessus_ATCC_1997 --------------RDRAHTRVQTGLRRIYGEMKGIDAVPVS--------
MAV_0881|M.avium_104 KGGGFFSFGIMHYYMTGVHTPGRTGVWKRYLEEVEKDPTLAYGPGRGAIG
Mflv_4097|M.gilvum_PYR-GCK ----------------EHLAKGIDDLRRRLEDAGRDPADVDITFTNDAGG
Mvan_5167|M.vanbaalenii_PYR-1 --------------FDVVHGLGTNRVGEGHVAQHDPDARPGMS-------
Mb1971|M.bovis_AF2122/97 AVDGTMGRAMREYVLPTFRMFGMTKFYKHNPSVPDDEVTPEYLAENTFVV
Rv3618|M.tuberculosis_H37Rv CTYG---------LPDFSRYFGAAGFVPLANTVEGTQSSREFVEQYAAKG
TH_3517|M.thermoresistible__bu ESIELSIETHRKYSSPFERGGEIPADYKAYADWFEKHDKQSYEQVLNSHL
MMAR_0308|M.marinum_M GPPKTPGYHASNLLIGTPEEIYHRITAAQAACSFCELTIVVQFGTMPYEQ
MUL_4814|M.ulcerans_Agy99 GPPKTPGYHASNLLIGTPEEIYHRITAAQAACSFCELTIVVQFGTMPYEQ
MSMEG_5626|M.smegmatis_MC2_155 GPP---GYHASNLLIGSPETVYEKLKAAQEACSFSEVTIVPQFGTMPYEE
MAB_3792|M.abscessus_ATCC_1997 ---------------GPPEEVAAGLRAVADAG--AEMILLNPVG-KDVAE
MAV_0881|M.avium_104 SPATVREFLRGYEESGVDEIILLLNPRSHEGTMESIELMGKEVLPEFIER
Mflv_4097|M.gilvum_PYR-GCK APG------------TDDFNADEFLAGAEELERAGVTWLQVNVPGDSLAH
Mvan_5167|M.vanbaalenii_PYR-1 ---------------AAEIVDRLSWLGAQGVTVSAVPIPKVRGVEEYLDY
Mb1971|M.bovis_AF2122/97 G--------------SVQTVVDKLEATYDQVGGFGHLLILGFDYSDNPGP
Rv3618|M.tuberculosis_H37Rv NCCIG----------TPDDAIAHIEDLLHRSGGFGTLLLLGHDWAPPPAT
TH_3517|M.thermoresistible__bu T------------LMGNPDRIIEKIRTVIDMGWRNIMLRMSRGGAMDRAK
MMAR_0308|M.marinum_M AMASTRLFAQEVLPAVHRMDAPLHPAALPANALA----------------
MUL_4814|M.ulcerans_Agy99 AMASTRLFAQEVLPAVHRMDAPLHPAALPANALA----------------
MSMEG_5626|M.smegmatis_MC2_155 AMESVKLFAAEVLPAVHDMPAPLHPSVLPESVTA----------------
MAB_3792|M.abscessus_ATCC_1997 DREQMERLAAEVIPQLA---------------------------------
MAV_0881|M.avium_104 DAKAVADKATRLAPVIEKVEARRPKSTAPQFDENYSFGGLPTGRGGKFTA
Mflv_4097|M.gilvum_PYR-GCK AVEAIEGFGETVIAQR----------------------------------
Mvan_5167|M.vanbaalenii_PYR-1 AQWVIEEIKPQVP-------------------------------------
Mb1971|M.bovis_AF2122/97 WKESLRLLAHEVMPRLNARLATKPATAVV---------------------
Rv3618|M.tuberculosis_H37Rv -FHSYELFARAVIPYFKGQLAAPRASHEWARGKRDQLIGRAGEAVVKAIT
TH_3517|M.thermoresistible__bu VRDSMKLFADEVIPAATELAKASA--------------------------
:
MMAR_0308|M.marinum_M -----------------------------
MUL_4814|M.ulcerans_Agy99 -----------------------------
MSMEG_5626|M.smegmatis_MC2_155 -----------------------------
MAB_3792|M.abscessus_ATCC_1997 -----------------------------
MAV_0881|M.avium_104 SEIPEAMAEINEGRVQAAQRAKEQQQQKK
Mflv_4097|M.gilvum_PYR-GCK -----------------------------
Mvan_5167|M.vanbaalenii_PYR-1 -----------------------------
Mb1971|M.bovis_AF2122/97 -----------------------------
Rv3618|M.tuberculosis_H37Rv EHVAEQGEAGS------------------
TH_3517|M.thermoresistible__bu -----------------------------