For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3517 | - | - | 100% (358) | putative luciferase |
| M. thermoresistible (build 8) | TH_3375 | - | 9e-22 | 28.37% (349) | PUTATIVE putative conserved hypothetical protein |
| M. thermoresistible (build 8) | TH_3390 | - | 2e-21 | 26.82% (358) | PUTATIVE luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0978c | - | 1e-18 | 32.12% (193) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2404 | - | 7e-22 | 30.54% (203) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3618 | - | 3e-19 | 32.97% (182) | monooxygenase |
| M. leprae Br4923 | MLBr_00269 | - | 3e-06 | 25.50% (149) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4628c | - | 3e-22 | 26.30% (346) | luciferase-like monooxygenase |
| M. marinum M | MMAR_0308 | - | 1e-22 | 31.22% (189) | monooxygenase |
| M. avium 104 | MAV_4445 | - | 1e-21 | 28.66% (328) | hypothetical protein MAV_4445 |
| M. smegmatis MC2 155 | MSMEG_5626 | - | 1e-25 | 25.07% (355) | luciferase |
| M. ulcerans Agy99 | MUL_4814 | - | 3e-22 | 30.69% (189) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_4242 | - | 5e-21 | 31.07% (177) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2404|M.gilvum_PYR-GCK ----MKISLFYEFPLPRPWS-----------DDDEHQLFQHGLDEVELAD
Mvan_4242|M.vanbaalenii_PYR-1 ----MKISLFYEFPLPRPWS-----------EDDEHQLFQHGLDEVELAD
MMAR_0308|M.marinum_M ----MKVNIGLGAHNSLDWERVLAEDYDRPPSTADWECVQATLALGDLAE
MUL_4814|M.ulcerans_Agy99 ----MKVNIGLGAHNSLDWERVLAEDYDRPPSTADWECVQATLALGDLAE
MSMEG_5626|M.smegmatis_MC2_155 ----MKVNLGTGAQNSRDWERVLAEDWSRPPATPDHQCVQAALALGDLAE
TH_3517|M.thermoresistible__bu ----LRFGVFILGDKPNHLS--------------HAQVLANVLEEAQWAE
Rv3618|M.tuberculosis_H37Rv MKAPLRFGVFITPFHPTGQS--------------PTVALQYDMERVVALD
Mb0978c|M.bovis_AF2122/97 ----MHYGLVLFTSDRGITP-----------AAAARLAESHGFRTFYVPE
MAV_4445|M.avium_104 ----MRFSIAIPQFDYDGFDG------------------AGLRSFLTRAE
MAB_4628c|M.abscessus_ATCC_199 ----MRFQLLDIVFHLPNPATR--------ALAPAAERLNRVIETAVLAE
MLBr_00269|M.leprae_Br4923 ---MAELRLGYKASAEQFAP-------------------RELVELGVAAE
. : :
Mflv_2404|M.gilvum_PYR-GCK KAGFSTVWLTEHHFL-------EEYCHSTAPELFLAAASQRTKNIRLGFG
Mvan_4242|M.vanbaalenii_PYR-1 KAGFSTVWLTEHHFL-------EEYCHSTAPELFLAAASQRTKNIRLGFG
MMAR_0308|M.marinum_M PLGFDGIWLPEHCG--------TPYGMTPNPIQALSYFAGRTERVNLGTF
MUL_4814|M.ulcerans_Agy99 PLGFDGIWLPEHCG--------TPYGMTPNPIQALSYFAGRTERVNLGTF
MSMEG_5626|M.smegmatis_MC2_155 PLGFDGIWFPEHHG--------TPYGMTPNPIQALTYFAGRTERVSLGTF
TH_3517|M.thermoresistible__bu EFGYDEIWLAEHHF--------SPYGTLADLPLVAAAIAAKTERIRIGTA
Rv3618|M.tuberculosis_H37Rv RLGYDEAWFGEHHS--------GGYELIACPEVFIAAAAERTTHIRLGTG
Mb0978c|M.bovis_AF2122/97 HTHIPVKRQAAHPTTGDASLPDDRYMRTLDPWVSLGAASAVTSRIRLATA
MAV_4445|M.avium_104 QLGFEGGWALEQIIG---------PAPPLAPLELLAYCAACTERLRLGVA
MAB_4628c|M.abscessus_ATCC_199 NLGFDSFAVGERHAG---------DVLSSAPTVLLGAVAAATDRILLSTG
MLBr_00269|M.leprae_Br4923 AHGMDSATVSDHFQPWR-----HQGGHASFSLSWMTAVGERTNRILLGTS
: . * .: :.
Mflv_2404|M.gilvum_PYR-GCK VMHLPPPINHPARIAERVATLDHLSNGR-VEFGTGEGSSVAELGG----F
Mvan_4242|M.vanbaalenii_PYR-1 VMHLPPPINHPARIAERVATLDHLSNGR-VEYGTGEGSSVAELGG----F
MMAR_0308|M.marinum_M VAVAP--WWHPIRLAHQMAYLDIISNGRYTTLGIGRGVSKGEFAA----V
MUL_4814|M.ulcerans_Agy99 VAVAP--WWHPIRLAHQMAYLDIISNGRYTTLGIGRGVSKGEFAA----V
MSMEG_5626|M.smegmatis_MC2_155 VAVVP--WWNPIRLATQIAYLDIVSNGRYTTIGLGRGVSKGEFAA----V
TH_3517|M.thermoresistible__bu CMVAP--FHDPIQLAERIALVDNLSGGR-FDAGFGRGYQAHEFKG----F
Rv3618|M.tuberculosis_H37Rv VVSLP--YHHPLMVADRWVLLDHLTRGR-VMFGTGPGALPSDAYM----M
Mb0978c|M.bovis_AF2122/97 VALPV--EHDPITLAKSIATLDHLSHGR-VSVGVGFGWNTDELVD----H
MAV_4445|M.avium_104 VLVTS--LHDPLQLASAVTAVDRLSHGR-LDIGVAPGGGTRKFAA----F
MAB_4628c|M.abscessus_ATCC_199 VTVLS--LLDPVRAAEDFATIDQLSRGR-LEIVIGKGNEDRQYPL----M
MLBr_00269|M.leprae_Br4923 VLTPT-FRYNPAVIGQAFATMGCLYPNR-VFLGVGTGEALNEVATGYQGA
.* . . :. : .* . * .
Mflv_2404|M.gilvum_PYR-GCK NIDPADKRAQWEEALEVSIRCMTEA--PFTGFKGEHVEMPARNVIPKPLQ
Mvan_4242|M.vanbaalenii_PYR-1 NIDPADKRTMWEEALEVSIRCMTEA--PFTGFKGEHVEMAARNVIPKPLQ
MMAR_0308|M.marinum_M GVPREESRQRFNETLDILALAFSGK--RFA-YEGEIFTVPEMSLRPEPFS
MUL_4814|M.ulcerans_Agy99 GVPREESRQRFNETLDTLALAFSGK--RFA-YEGEIFTVPEMSLRPEPFS
MSMEG_5626|M.smegmatis_MC2_155 GVPREESRQRFNETLDILKLAFSGE--RFS-YEGEIFSFPEMSLRPEPIS
TH_3517|M.thermoresistible__bu GIPMDEATARYQECVEIVDLLLTQE--NVT-YEGKFWQLHDVTVHPRPVQ
Rv3618|M.tuberculosis_H37Rv GIDPVEQRRMMQESLEAILALFRAAPDERIDRHSDWFTLREAQLHIRPYT
Mb0978c|M.bovis_AF2122/97 GVPPGRRRTMLREYLEAMRALWTQE---EACYDGEFVKFGPSWAWPKPVQ
MAV_4445|M.avium_104 GVDKDTFVAYFTEGLKLMKAAWSDD--PRVTFHGRFRDVDDLPIAPKPVQ
MAB_4628c|M.abscessus_ATCC_199 GLDIAKQYEYLQENYELLRRLLREE--HVDWVGVHRHPLADATTLPRPYD
MLBr_00269|M.leprae_Br4923 WPEFKERFARLRESVRLMRELWRGD---RVDFDGDYYQLKGASIYDVPEG
* . *
Mflv_2404|M.gilvum_PYR-GCK QPHPP-VWVACTRPSSVGMAAEKAIGALSFA---YTGPEALKDRVDGYYK
Mvan_4242|M.vanbaalenii_PYR-1 QPHPP-VWVACTRPSSVQMAAQKAIGALSFA---YTGPEALKERVDGYYK
MMAR_0308|M.marinum_M SDLFARIYSSSSTAESLEILARRGMVPLFVG---NKPIEDAGREVQQVNT
MUL_4814|M.ulcerans_Agy99 SDLFARIYSSSSTAESLEILARRGMVPLFVG---NKPIEDAGREVQQVNT
MSMEG_5626|M.smegmatis_MC2_155 TDLYDRIYSSSSTAESLEILSRRGMVPLFVG---NKPITDAGEEVKKVNT
TH_3517|M.thermoresistible__bu NPIPVWGTVMKT-PSSFEWLADKGFGAIIGNP--YQVDPDLQGALDLYLE
Rv3618|M.tuberculosis_H37Rv WPYPEIATAAMISPSGPRLAGALGTSLLSLSMSVPGGYAALETAWGVVRE
Mb0978c|M.bovis_AF2122/97 PHIPVLVGAAGT-EKNFKWIARSADGWITTP-----RDVDIDEPVKLLQD
MAV_4445|M.avium_104 RPHPP-IWFGGLAPKALARAVRHGDAFMGAG---SSTTEAFAGAVAVLRR
MAB_4628c|M.abscessus_ATCC_199 GPFRIWHGSATS-TFAVELAAKWGDPIVTAN--ALQPKENYRVLIDRYRE
MLBr_00269|M.leprae_Br4923 G---VPIYIAAGGPEVAKYAGRAGEGFVCTSG--KGEELYTEKLIPAVLE
. :
Mflv_2404|M.gilvum_PYR-GCK DFEEKGTPITPAINPNLLAIGGDLSMMVAKTDEEALKRLGIGGGFFSFGI
Mvan_4242|M.vanbaalenii_PYR-1 EFEEQGAPITPAINPNILAIGGDLSMMVAKTDEEALERLGIGGGFFSFGI
MMAR_0308|M.marinum_M FRQEEG--LPPCQPKNVMFMYCTASAEQAAESEEWIWTANR-----DVTV
MUL_4814|M.ulcerans_Agy99 FRQEEG--LPPCQPKNVMFMYCTASAEQAAESEEWIWTANR-----DVTV
MSMEG_5626|M.smegmatis_MC2_155 FRAEEG--LPPCQPKNVMFMYCTNSQDEIEQTEEWIWTANR-----DVNV
TH_3517|M.thermoresistible__bu TQAKKG--LEAATGNVWALLNAFCHQDDAFARSYPRESIEL-----SIET
Rv3618|M.tuberculosis_H37Rv QAAKAGRGEPDRADWRVLSIMHLSDSRDQAIDDCTYGLPDFSR---YFGA
Mb0978c|M.bovis_AF2122/97 IWAAAG----------RDGLPQIVALDVKPVPDKLARWAELG----VTEV
MAV_4445|M.avium_104 ELDEQQ--RDPAEFTIGKRVYLTVDDDAARARERVLAGLSR---------
MAB_4628c|M.abscessus_ATCC_199 LYAHHGHDPAQLYVGAGSGGLYLADTTEQAIAQYRPIYEAR------LAQ
MLBr_00269|M.leprae_Br4923 GAAVAGRDADDIDKMIEIKMSYDPDPEQALSNIRFWAPLSL-----AAEQ
Mflv_2404|M.gilvum_PYR-GCK MHYYLTGMHTPG-RTGVWELYEKAVKEDPTLAYGPGRGAIGSPETVREFL
Mvan_4242|M.vanbaalenii_PYR-1 MHYYLTGMHTPG-RTGVWELYEKAVKEDPTLAYGPGRGAIGSPDTVREFL
MMAR_0308|M.marinum_M HYGFADASNFKG-VKGYEAYAAREASATAVLASSVTGDAKGGPPKT----
MUL_4814|M.ulcerans_Agy99 HYGFADASNFKG-VKGYEAYAAREASATAVLASSVTGDAKGGPPKT----
MSMEG_5626|M.smegmatis_MC2_155 HYGFADASNFRG-VKGYEAYAAREASATAVLASEVGNQKKGGPP------
TH_3517|M.thermoresistible__bu HRKYSSPFERGGEIPADYKAYADWFEKHDKQSYEQVLNSH----------
Rv3618|M.tuberculosis_H37Rv AGFVPLANTVEG--TQSSREFVEQYAAKGNCCIGTPDDAIAHIEDLLHRS
Mb0978c|M.bovis_AF2122/97 LFGMPDRS------ADDAAAYVERLAAKLACCV-----------------
MAV_4445|M.avium_104 -------------------IYGRMPGVADVPVSGTP--------------
MAB_4628c|M.abscessus_ATCC_199 MAKLKAHPKAVG--KFPSFESIEDAADRGPVLAGSP--------------
MLBr_00269|M.leprae_Br4923 KHSIDDPIEMEK---VADALPIEQVAKRWIVVSDPD--------------
Mflv_2404|M.gilvum_PYR-GCK RGYEASGVDEIILLLNPRSHEGTMESIEIMGRDILPEFIERDEKAVKDKA
Mvan_4242|M.vanbaalenii_PYR-1 RGYEASGVDEIILLLNPRSHEGTMESIEIMGRDILPEFIERDEKAVKDKA
MMAR_0308|M.marinum_M PGYHAS----NLLIGTP---------------------------------
MUL_4814|M.ulcerans_Agy99 PGYHAS----NLLIGTP---------------------------------
MSMEG_5626|M.smegmatis_MC2_155 -GYHAS----NLLIGSP---------------------------------
TH_3517|M.thermoresistible__bu ----------LTLMGNP---------------------------------
Rv3618|M.tuberculosis_H37Rv GGFGTLLLLGHDWAPPP---------------------------------
Mb0978c|M.bovis_AF2122/97 --------------------------------------------------
MAV_4445|M.avium_104 --------------------------------------------------
MAB_4628c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00269|M.leprae_Br4923 --------------------------------------------------
Mflv_2404|M.gilvum_PYR-GCK KRLEPVIEKVEARRQSWDAPMFDETYSFGGLPTGRGGKFTAGEIPEAMAE
Mvan_4242|M.vanbaalenii_PYR-1 KRLEPVIEKVEARRQSWDAPLFDETYAFGGLPTGRGGKFTAGEIPEAMAE
MMAR_0308|M.marinum_M ---EEIYHRITAAQAACSFCELTIVVQFGTMPYEQAMASTRLFAQEVLPA
MUL_4814|M.ulcerans_Agy99 ---EEIYHRITAAQAACSFCELTIVVQFGTMPYEQAMASTRLFAQEVLPA
MSMEG_5626|M.smegmatis_MC2_155 ---ETVYEKLKAAQEACSFSEVTIVPQFGTMPYEEAMESVKLFAAEVLPA
TH_3517|M.thermoresistible__bu ---DRIIEKIRTVIDMGWRNIMLRMSRGGAMDRAKVRDSMKLFADEVIPA
Rv3618|M.tuberculosis_H37Rv -ATFHSYELFARAVIPYFKGQLAAPRASHEWARGKRDQLIGRAGEAVVKA
Mb0978c|M.bovis_AF2122/97 --------------------------------------------------
MAV_4445|M.avium_104 ---GDVVRGLREVIDAGAQTLLLNPVG---ADVAENHEQMERLAAEVIPQ
MAB_4628c|M.abscessus_ATCC_199 ---ERVAEKILDWHEAFG-HEFQSISLSPEADFEEQKDTLRRFAEEVVPL
MLBr_00269|M.leprae_Br4923 ----------EAVARVGQYVTWGLNHLVFHAPGHNQRRFLELFEKDLAPR
Mflv_2404|M.gilvum_PYR-GCK INEGRVKAAQAEKDARAAKEAAG-
Mvan_4242|M.vanbaalenii_PYR-1 INEGRVKAAQAEKDAKAAKEAAS-
MMAR_0308|M.marinum_M VHRMDAPLHPAALPANALA-----
MUL_4814|M.ulcerans_Agy99 VHRMDAPLHPAALPANALA-----
MSMEG_5626|M.smegmatis_MC2_155 VHDMPAPLHPSVLPESVTA-----
TH_3517|M.thermoresistible__bu ATELAKASA---------------
Rv3618|M.tuberculosis_H37Rv ITEHVAEQGEAGS-----------
Mb0978c|M.bovis_AF2122/97 ------------------------
MAV_4445|M.avium_104 LN----------------------
MAB_4628c|M.abscessus_ATCC_199 VRAEVKSTLWGPLDTRRAKGFTAA
MLBr_00269|M.leprae_Br4923 LRRLG-------------------