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KVNIGLGAHNSLDWERVLAEDYDRPPSTADWECVQATLALGDLAEPLGFDGIWLPEHCGTPYGMTPNPIQ ALSYFAGRTERVNLGTFVAVAPWWHPIRLAHQMAYLDIISNGRYTTLGIGRGVSKGEFAAVGVPREESRQ RFNETLDTLALAFSGKRFAYEGEIFTVPEMSLRPEPFSSDLFARIYSSSSTAESLEILARRGMVPLFVGN KPIEDAGREVQQVNTFRQEEGLPPCQPKNVMFMYCTASAEQAAESEEWIWTANRDVTVHYGFADASNFKG VKGYEAYAAREASATAVLASSVTGDAKGGPPKTPGYHASNLLIGTPEEIYHRITAAQAACSFCELTIVVQ FGTMPYEQAMASTRLFAQEVLPAVHRMDAPLHPAALPANALA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4814 | - | - | 100% (393) | monooxygenase |
| M. ulcerans Agy99 | MUL_2716 | - | 4e-16 | 31.87% (160) | hypothetical protein MUL_2716 |
| M. ulcerans Agy99 | MUL_1043 | - | 1e-12 | 28.07% (171) | hypothetical protein MUL_1043 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1971 | - | 4e-11 | 22.65% (393) | monooxygenase |
| M. gilvum PYR-GCK | Mflv_4429 | - | 6e-17 | 25.23% (333) | luciferase family protein |
| M. tuberculosis H37Rv | Rv1936 | - | 4e-11 | 22.65% (393) | monooxygenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3792 | - | 3e-13 | 35.29% (136) | luciferase-like protein |
| M. marinum M | MMAR_0308 | - | 0.0 | 99.75% (393) | monooxygenase |
| M. avium 104 | MAV_5129 | - | 3e-13 | 32.35% (136) | hypothetical protein MAV_5129 |
| M. smegmatis MC2 155 | MSMEG_5626 | - | 0.0 | 79.64% (393) | luciferase |
| M. thermoresistible (build 8) | TH_3517 | - | 3e-22 | 30.69% (189) | PUTATIVE putative luciferase |
| M. vanbaalenii PYR-1 | Mvan_1925 | - | 2e-15 | 24.77% (331) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4814|M.ulcerans_Agy99 MKVNIGLGAHNSLDWERVLAEDYDRPPSTADWECVQATLALGDLAEPLGF
MMAR_0308|M.marinum_M MKVNIGLGAHNSLDWERVLAEDYDRPPSTADWECVQATLALGDLAEPLGF
MSMEG_5626|M.smegmatis_MC2_155 MKVNLGTGAQNSRDWERVLAEDWSRPPATPDHQCVQAALALGDLAEPLGF
Mb1971|M.bovis_AF2122/97 MEIGIFLMP--------------AHPPERTLYDATRWDLDVIELADQLGY
Rv1936|M.tuberculosis_H37Rv MEIGIFLMP--------------AHPPERTLYDATRWDLDVIELADQLGY
Mflv_4429|M.gilvum_PYR-GCK MRFGNFMAP--------------FHPVGQNPTLALERDLDLIVAMDRLGF
Mvan_1925|M.vanbaalenii_PYR-1 MRFGNFMAP--------------FHPVGQNPTLALERDLDLIAAMDRLGF
MAB_3792|M.abscessus_ATCC_1997 MRFSISIPQ---------------FDTGSFDGDGVR---DYLARAEELGF
MAV_5129|M.avium_104 MRFTITHPMHS-----------HPYNRELVSGDAIAKVAAATEAAGIHGF
TH_3517|M.thermoresistible__bu LRFGVFILG--------------DKPNHLSHAQVLANVLEEAQWAEEFGY
:.. *:
MUL_4814|M.ulcerans_Agy99 ----DGIWLPEHCGTPYGMTPNPIQALSYFAGRTERVNLGTFVAVAPWWH
MMAR_0308|M.marinum_M ----DGIWLPEHCGTPYGMTPNPIQALSYFAGRTERVNLGTFVAVAPWWH
MSMEG_5626|M.smegmatis_MC2_155 ----DGIWFPEHHGTPYGMTPNPIQALTYFAGRTERVSLGTFVAVVPWWN
Mb1971|M.bovis_AF2122/97 ----VEAWVGEHFTVPWEPICAPDLLLAQALLRTQQIKLAPGAHLLPYHH
Rv1936|M.tuberculosis_H37Rv ----VEAWVGEHFTVPWEPICAPDLLLAQALLRTQQIKLAPGAHLLPYHH
Mflv_4429|M.gilvum_PYR-GCK ----HEAWVGEHHSAGFEIIASPEVFLGVAAERTKHIRLGTGVSSLPYHH
Mvan_1925|M.vanbaalenii_PYR-1 ----HEAWVGEHHSAGFEIIASPEVFIGIAAERTKHIKLGTGVSSLPYHH
MAB_3792|M.abscessus_ATCC_1997 ----AGGWTLEQT-VGSSPIIAPLELLAYAAACTTRLRLGVAVLVASQHD
MAV_5129|M.avium_104 GFTDHPAPSQRWLEAGGHDALDPFVALGFAAATTSTLRLIPNIVVLPYRN
TH_3517|M.thermoresistible__bu ----DEIWLAEHHFSPYGTLADLPLVAAAIAAKTERIRIGTACMVAPFHD
. * : : . .
MUL_4814|M.ulcerans_Agy99 PIRLAHQMAYLDIISNGRYTTLGIGRGVSKGEFAAVGVPRE--ESRQRFN
MMAR_0308|M.marinum_M PIRLAHQMAYLDIISNGRYTTLGIGRGVSKGEFAAVGVPRE--ESRQRFN
MSMEG_5626|M.smegmatis_MC2_155 PIRLATQIAYLDIVSNGRYTTIGLGRGVSKGEFAAVGVPRE--ESRQRFN
Mb1971|M.bovis_AF2122/97 PVELAHRVAYFDHLAQGR-FMLGVGASGIPGDWALYDVDGKNGEHREMTR
Rv1936|M.tuberculosis_H37Rv PVELAHRVAYFDHLAQGR-FMLGVGASGIPGDWALYDVDGKNGEHREMTR
Mflv_4429|M.gilvum_PYR-GCK PLMLADRMVLLDHLTRGR-VMLGCGPGQLTSDAHMLGIPAD--EQRPRME
Mvan_1925|M.vanbaalenii_PYR-1 PLLLADRMVLLDHLTRGR-VMLGCGPGQLTSDAHMLGIPAD--AQRPRME
MAB_3792|M.abscessus_ATCC_1997 PLQLAAAVTAVDRLSHGR-LDVGVAPGGGARNFAAFGVDKQ--TFIARFT
MAV_5129|M.avium_104 PFVVAKSGATLDLLSGGR-FTLAVGVGYLKREFAALGVSYD--ERAELFE
TH_3517|M.thermoresistible__bu PIQLAERIALVDNLSGGR-FDAGFGRGYQAHEFKGFGIPMD--EATARYQ
*. :* . .* :: ** . . . : .: .
MUL_4814|M.ulcerans_Agy99 ETLDTLALAFSGKRFAYEGEIFTVPEMSLRPEPFSSDLFARIYSSSSTAE
MMAR_0308|M.marinum_M ETLDILALAFSGKRFAYEGEIFTVPEMSLRPEPFSSDLFARIYSSSSTAE
MSMEG_5626|M.smegmatis_MC2_155 ETLDILKLAFSGERFSYEGEIFSFPEMSLRPEPISTDLYDRIYSSSSTAE
Mb1971|M.bovis_AF2122/97 EALEIMLRIWTEDEPWEHRGKYWNANGIAPMFEGLMRRHIKPYQKPHPPI
Rv1936|M.tuberculosis_H37Rv EALEIMLRIWTEDEPWEHRGKYWNANGIAPMFEGLMRRHIKPYQKPHPPI
Mflv_4429|M.gilvum_PYR-GCK QCLDAIVRLLRGETVTMHTDGFTLQD---------ARLQLKPYSEPCFDI
Mvan_1925|M.vanbaalenii_PYR-1 QSLDAIVRLLRGETVTMHTDGFTLQD---------ARLQLKPYSDPCFDI
MAB_3792|M.abscessus_ATCC_1997 EGLDLMKLAWSDEERITFRGRFRDVADLAFQPKPVQRPHPPIWFGGHAPA
MAV_5129|M.avium_104 EALQVIRAVWTGDDISFEGRHFSARG-ITAHPRPVSSPHPPIWIGGNTAA
TH_3517|M.thermoresistible__bu ECVEIVDLLLTQENVTYEG-KFWQLHDVTVHPRPVQNPIPVWGTVMKTPS
: :: : . :
MUL_4814|M.ulcerans_Agy99 SLEILARRGMVPLFVGNKPIEDAGR-EVQQVNTFRQEEGLPPCQPKNVMF
MMAR_0308|M.marinum_M SLEILARRGMVPLFVGNKPIEDAGR-EVQQVNTFRQEEGLPPCQPKNVMF
MSMEG_5626|M.smegmatis_MC2_155 SLEILSRRGMVPLFVGNKPITDAGE-EVKKVNTFRAEEGLPPCQPKNVMF
Mb1971|M.bovis_AF2122/97 GVTGFSAGSETLKLAGERGY-----------IPMSLDLNTEYVATHWDAV
Rv1936|M.tuberculosis_H37Rv GVTGFSAGSETLKLAGERGY-----------IPMSLDLNTEYVATHWDAV
Mflv_4429|M.gilvum_PYR-GCK AVAASFS-PTGPRGAGRHGIGML-------SIAATARQGMDLLAQHWNTW
Mvan_1925|M.vanbaalenii_PYR-1 AVAASFS-PTGPRGAGRHGIGML-------SIAATAKQGMDLLAQHWNTW
MAB_3792|M.abscessus_ATCC_1997 ALARAVRFGDAFLGAG--------------------SSTTAAFAEEVTTI
MAV_5129|M.avium_104 ARQRVADYGDGWCPFPAPP-------------QLARTAGTAVIDSVAKLA
TH_3517|M.thermoresistible__bu SFEWLADKGFGAIIGNPYQVDPDLQGALDLYLETQAKKGLEAATGNVWAL
.
MUL_4814|M.ulcerans_Agy99 MYCTASAEQAAESEEWIWTANRDVTVHYGFADASNFKG-----VKGYEAY
MMAR_0308|M.marinum_M MYCTASAEQAAESEEWIWTANRDVTVHYGFADASNFKG-----VKGYEAY
MSMEG_5626|M.smegmatis_MC2_155 MYCTNSQDEIEQTEEWIWTANRDVNVHYGFADASNFRG-----VKGYEAY
Mb1971|M.bovis_AF2122/97 EEGALRSGRTPDRRDWRLVREVLVAETDEQAFRYAVDGTMGRAMREYVLP
Rv1936|M.tuberculosis_H37Rv EEGALRSGRTPDRRDWRLVREVLVAETDEQAFRYAVDGTMGRAMREYVLP
Mflv_4429|M.gilvum_PYR-GCK DEVAREHGHQADRSKWRLVGPMHLAETREQAERDVEYG-----IAEFSRY
Mvan_1925|M.vanbaalenii_PYR-1 EEVAREHGHVADRAKWRLVGPMHLAETREQAERDVEYG-----IAQFSQY
MAB_3792|M.abscessus_ATCC_1997 HRELAIQGKDPARFTIGKRVYLMIDDDRDRAHTRVQTG------------
MAV_5129|M.avium_104 DGIADLRRRCDAAQRDWSTIDITFTNFEGGSPADDEFN------------
TH_3517|M.thermoresistible__bu LNAFCHQDDAFARSYPRESIELSIETHRKYSSPFERGGEIPADYKAYADW
. : .
MUL_4814|M.ulcerans_Agy99 AAREASATAVLASSVTGDAKGGPPKTPGYHASNLLIGTPEEIYHRITA--
MMAR_0308|M.marinum_M AAREASATAVLASSVTGDAKGGPPKTPGYHASNLLIGTPEEIYHRITA--
MSMEG_5626|M.smegmatis_MC2_155 AAREASATAVLASEVGNQKKGGPP---GYHASNLLIGSPETVYEKLKA--
Mb1971|M.bovis_AF2122/97 TFRMFGMTKFYKHNPSVPDDEVTPE--YLAENTFVVGSVQTVVDKLEATY
Rv1936|M.tuberculosis_H37Rv TFRMFGMTKFYKHNPSVPDDEVTPE--YLAENTFVVGSVQTVVDKLEATY
Mflv_4429|M.gilvum_PYR-GCK FTHILPSGPVQGDTP----EEIIAN--NRQSGFAVIGTPDDAIAKISELV
Mvan_1925|M.vanbaalenii_PYR-1 FSHILPAGPVQGDTP----AEIIAN--NHASGFAVIGTPQDAIAKIEELV
MAB_3792|M.abscessus_ATCC_1997 LRRIYGEMKGIDAVP-------------------VSGPPEEVAAGLRA--
MAV_5129|M.avium_104 --------------------------------------ADAYLDGLDK--
TH_3517|M.thermoresistible__bu FEKHDKQSYEQVLNS----------------HLTLMGNPDRIIEKIRT--
: :
MUL_4814|M.ulcerans_Agy99 AQAACSFCELTIVVQFGTMPYEQAMASTRLFAQEVLPAVHRMDAPLHPAA
MMAR_0308|M.marinum_M AQAACSFCELTIVVQFGTMPYEQAMASTRLFAQEVLPAVHRMDAPLHPAA
MSMEG_5626|M.smegmatis_MC2_155 AQEACSFSEVTIVPQFGTMPYEEAMESVKLFAAEVLPAVHDMPAPLHPSV
Mb1971|M.bovis_AF2122/97 DQVGG-FGHLLILGFDYSDNPGPWKESLRLLAHEVMPRLNARLATKPATA
Rv1936|M.tuberculosis_H37Rv DQVGG-FGHLLILGFDYSDNPGPWKESLRLLAHEVMPRLNARLATKPATA
Mflv_4429|M.gilvum_PYR-GCK EASDGGFGAFLLFDHDWAP-PAAKLRSYELFAQYVIPHFTGQLSAPIASR
Mvan_1925|M.vanbaalenii_PYR-1 EASNGGFGTFLLFDHDWAP-PAAKLRSYELFAEYVIPHFTGQLSAPIASR
MAB_3792|M.abscessus_ATCC_1997 ---VADAGAEMILLNPVGKDVAEDREQMERLAAEVIPQLA----------
MAV_5129|M.avium_104 ---LAKLGVTWVSVHLPGDSMAHALETLDRFRTLVVDAA-----------
TH_3517|M.thermoresistible__bu VIDMGWRNIMLRMSRGGAMDRAKVRDSMKLFADEVIPAATELAKASA---
: *:
MUL_4814|M.ulcerans_Agy99 LPANALA-------------------------------
MMAR_0308|M.marinum_M LPANALA-------------------------------
MSMEG_5626|M.smegmatis_MC2_155 LPESVTA-------------------------------
Mb1971|M.bovis_AF2122/97 VV------------------------------------
Rv1936|M.tuberculosis_H37Rv VV------------------------------------
Mflv_4429|M.gilvum_PYR-GCK DWVTESGRVFVDQATHAIGRAIESHAAEQQAKQSRTSD
Mvan_1925|M.vanbaalenii_PYR-1 DWVTESGRTFVDQAAHAIGKAIEDHAAEQQAKSPTPS-
MAB_3792|M.abscessus_ATCC_1997 --------------------------------------
MAV_5129|M.avium_104 --------------------------------------
TH_3517|M.thermoresistible__bu --------------------------------------