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NIRTGMKIAAASTATAAMALGAAPLAMAETEAGFGEAQDLVAPTGDTASVTVTDIALSSDQIPTEVEGQL YEATATIEAKEGTVTPVLSNFNARTADGQSYQAVYEVPASEGNPEPLTEGASTTGKVYFDVKGEAPDSVV YSDVGSDEVIWTDDPGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5617 | - | - | 100% (158) | immunogenic protein MPT63 |
| M. smegmatis MC2 155 | MSMEG_5412 | - | 6e-30 | 43.95% (157) | immunogenic protein MPT63 |
| M. smegmatis MC2 155 | MSMEG_0828 | - | 7e-28 | 43.95% (157) | immunogenic protein MPT63 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1961c | mpt63 | 1e-19 | 36.71% (158) | immunogenic protein MPT63 (antigen MPT63/MPB63) (16 KD |
| M. gilvum PYR-GCK | Mflv_1515 | - | 2e-29 | 43.04% (158) | FHA domain-containing protein |
| M. tuberculosis H37Rv | Rv1926c | mpt63 | 1e-19 | 36.71% (158) | immunogenic protein MPT63 (antigen MPT63/MPB63) (16 kDa |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1026c | - | 5e-27 | 40.94% (149) | hypothetical protein MAB_1026c |
| M. marinum M | MMAR_1823 | - | 1e-23 | 44.97% (149) | hypothetical protein MMAR_1823 |
| M. avium 104 | MAV_3737 | - | 2e-19 | 35.81% (148) | hypothetical protein MAV_3737 |
| M. thermoresistible (build 8) | TH_4151 | - | 1e-20 | 38.36% (146) | PUTATIVE putative FHA domain containing protein |
| M. ulcerans Agy99 | MUL_2071 | - | 4e-16 | 41.67% (132) | hypothetical protein MUL_2071 |
| M. vanbaalenii PYR-1 | Mvan_5241 | - | 1e-27 | 44.23% (156) | FHA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1961c|M.bovis_AF2122/97 -MKLTTMIKTAVAVVAMAAIATFAAPVALAAYPITGKLGSELTMTDTVGQ
Rv1926c|M.tuberculosis_H37Rv -MKLTTMIKTAVAVVAMAAIATFAAPVALAAYPITGKLGSELTMTDTVGQ
Mflv_1515|M.gilvum_PYR-GCK -MKFKPALVAAATAAAATAVALGGAATASADTEVQ-WLGQPGELVNGT--
Mvan_5241|M.vanbaalenii_PYR-1 -MKFKPTVAAIITTAAAAAVGVVGAGSASADAEVQ-YLGQPGELVNGS--
MAB_1026c|M.abscessus_ATCC_199 -MKIN-VPITAAVAAAAAAAGLALMPTAGADTT----LGQQGRLTNGD--
MSMEG_5617|M.smegmatis_MC2_155 -MNIRTGMKIAAASTATAAMALGAAPLAMAETEAG--FGEAQDLVAPTG-
TH_4151|M.thermoresistible__bu -MNSK-ILAAPVVLATAAGLALATAAPAPARPGVA-DFGATQHLHDGG--
MMAR_1823|M.marinum_M -------MKTAVGAAAIAAASVFGAASASAAPPTIQGFGTSERLVDGP--
MUL_2071|M.ulcerans_Agy99 MEFIATTMKTAVGAAAIAAASVFGAASASAAPPTIQGFGTSERLVDGP--
MAV_3737|M.avium_104 MKVTKNAVLTAAAAGGIAAASVFAATPAVAAP-NIQGFGVSEQLVDGP--
:. . * * :* :
Mb1961c|M.bovis_AF2122/97 VVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVSQFNAR
Rv1926c|M.tuberculosis_H37Rv VVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVSQFNAR
Mflv_1515|M.gilvum_PYR-GCK VVQHWTVSHLKPSTDTIP-YQPVGTLWEATASDEAVAGNVTPIISNLNAR
Mvan_5241|M.vanbaalenii_PYR-1 VIQHWTVTGLKPSSDVIP-YRPVGTLWEATATDEAIAGTVTPIVSNLNAR
MAB_1026c|M.abscessus_ATCC_199 VVQAWTISDLKVSTDQLP-YQPKGTLWEATATDEAIQGSVIPIVANFNAK
MSMEG_5617|M.smegmatis_MC2_155 DTASVTVTDIALSSDQIP-TEVEGQLYEATATIEAKEGTVTPVLSNFNAR
TH_4151|M.thermoresistible__bu VTIAYTLEELEPSDDVVSNVALQGRLWEVSVTVEAVEGAATPVIPFFNAR
MMAR_1823|M.marinum_M MVTSYTVGNLQLSDVTIAGYLPQGQLYSADVTARSVTGTITPLVSSFNAR
MUL_2071|M.ulcerans_Agy99 MVTSYTVGNLQLSDVTIAGYLPQGQLYSADVTGRSVTGTITPLVSSFSAR
MAV_3737|M.avium_104 LVTDYTVSNLQPSNVSIPGYTPKGTLYQADISVRSDGGVVTPMVHDFIAR
.: : * :. * ::.. : .: * * : : *:
Mb1961c|M.bovis_AF2122/97 TADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTIVAMNN
Rv1926c|M.tuberculosis_H37Rv TADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTIVAMNN
Mflv_1515|M.gilvum_PYR-GCK AKNGDTYRVLFGVATTQGVNPAPLAQGHKTSGKIYFDVTGEAPDSVFYST
Mvan_5241|M.vanbaalenii_PYR-1 AENGDTYRVLFGVATEQGVNPSTLAQGQKTTGKIYFDVTGQQPDSVFYSD
MAB_1026c|M.abscessus_ATCC_199 ANDGETYRVLYGVASAQGVNPGTLSQGEKTTGKIYFDVTGANPETVTYTS
MSMEG_5617|M.smegmatis_MC2_155 TADGQSYQAVYEVPASEG-NPEPLTEGASTTGKVYFDVKGEAPDSVVYSD
TH_4151|M.thermoresistible__bu SADGQNYRALFTAVGEEALSGATLGQGQETEGNIYFDVTGAPPTEVVYND
MMAR_1823|M.marinum_M AANGDTYGVVNEVPAPGGLNPAPILQGNSQSGVLYFDVTGPPPNGVVYND
MUL_2071|M.ulcerans_Agy99 AANGDTYGVVNEVPAPGGLNPAPILQGNSQSGVLYF--------------
MAV_3737|M.avium_104 GPNGQNYRVIDNVAVPNGLSPAPIPQGTESTGTLYFDVTGAPPNGVVYND
:* .* .: . . .: :* . * :**
Mb1961c|M.bovis_AF2122/97 GMEDLLIWEP----------------------------------------
Rv1926c|M.tuberculosis_H37Rv GMEDLLIWEP----------------------------------------
Mflv_1515|M.gilvum_PYR-GCK GDAEELLWLQAPPPATGSGTSGSTSGSSSSGASSAPSAAAETTAPETPAS
Mvan_5241|M.vanbaalenii_PYR-1 GGSEVLLWLEAPP-APATGSAG--SGASGYGSEASPSAAADTATPETPGT
MAB_1026c|M.abscessus_ATCC_199 GDEDLLTWKAAPAAAPAQRSGGS-TQSHGSTPAPATSTAPTTATPAPAAV
MSMEG_5617|M.smegmatis_MC2_155 VGSDEVIWTDDPGQ------------------------------------
TH_4151|M.thermoresistible__bu AVQDRLIWR-----------------------------------------
MMAR_1823|M.marinum_M GVQDVLIWTSNV--------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MAV_3737|M.avium_104 GMQDVLMWTSNVPSSAPGAPNSPAPGAPNSPAPGAPPAPAAHT-------
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1515|M.gilvum_PYR-GCK ---------------TPAAEPAAVGSATPASVPSGSSGTPLPE----GSS
Mvan_5241|M.vanbaalenii_PYR-1 ---------------TPAAETPTSVVPTPVAAPAGSSGTPLPE----GSS
MAB_1026c|M.abscessus_ATCC_199 PAGSQGTPLPAGSQGTPVDEQAPAATPTPTVAPVTATPTPAPATPTPGAE
MSMEG_5617|M.smegmatis_MC2_155 --------------------------------------------------
TH_4151|M.thermoresistible__bu --------------------------------------------------
MMAR_1823|M.marinum_M --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MAV_3737|M.avium_104 --------------------------------------------------
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1515|M.gilvum_PYR-GCK GTPLP-EGSSGTPLPEGSS-----GTPLPANAAPPAEAAP-APVPAAA--
Mvan_5241|M.vanbaalenii_PYR-1 GTPLP-EGSSGTPLPAGAAPVEAGPAPVPAGVAPAPHGSSGTPLPAGAPA
MAB_1026c|M.abscessus_ATCC_199 GTPLNSTAVPASPAPATATP----AVPVPEGAAPQTGTPPVAAVPGVP-A
MSMEG_5617|M.smegmatis_MC2_155 --------------------------------------------------
TH_4151|M.thermoresistible__bu --------------------------------------------------
MMAR_1823|M.marinum_M --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MAV_3737|M.avium_104 --------------------------------------------------
Mb1961c|M.bovis_AF2122/97 -------------------------
Rv1926c|M.tuberculosis_H37Rv -------------------------
Mflv_1515|M.gilvum_PYR-GCK ------TPAPAAPTTTVAVPAPPA-
Mvan_5241|M.vanbaalenii_PYR-1 VEGVQPAPAPGAPTTTVVVPAPPA-
MAB_1026c|M.abscessus_ATCC_199 VPASDSVPHGQRAAGSQGTPVSTEG
MSMEG_5617|M.smegmatis_MC2_155 -------------------------
TH_4151|M.thermoresistible__bu -------------------------
MMAR_1823|M.marinum_M -------------------------
MUL_2071|M.ulcerans_Agy99 -------------------------
MAV_3737|M.avium_104 -------------------------