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KISQLTIAAAAALAISGAAGTAGMATAFAEAAQAAQVSANPLGSQARLENGDVVQAWTISDLKPSSDPIP YAVQGTLWEATATDEAVSGSVIPIVSNLNARAANGENYRVLFQVATPQGVNPSTLAPGQKTTGKVYFDVT GEAPTTVVYNDGERDLLAWSQTAASTTSPRPAATGSGTSASTPARTAPVTTAPASNTPATELVPESPAVA PTGAAPAAAPGAGAAATDIPGSTVPPLAEDAADEALAEELTEDLPDELSQDSVTPGESVGTPLPAAVQQA PAAPAPGQPAPAAPGAQDIPAAPAGEVPAAPVTPAPAAPVDGSTTPTVPAGSDAPLTAGGIPTLVPAANP GAPTP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0828 | - | - | 100% (356) | immunogenic protein MPT63 |
| M. smegmatis MC2 155 | MSMEG_5412 | - | 5e-77 | 48.57% (350) | immunogenic protein MPT63 |
| M. smegmatis MC2 155 | MSMEG_5617 | - | 2e-27 | 43.95% (157) | immunogenic protein MPT63 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1961c | mpt63 | 4e-32 | 46.01% (163) | immunogenic protein MPT63 (antigen MPT63/MPB63) (16 KD |
| M. gilvum PYR-GCK | Mflv_1515 | - | 2e-60 | 47.17% (318) | FHA domain-containing protein |
| M. tuberculosis H37Rv | Rv1926c | mpt63 | 5e-32 | 46.01% (163) | immunogenic protein MPT63 (antigen MPT63/MPB63) (16 kDa |
| M. leprae Br4923 | MLBr_01506 | - | 7e-08 | 26.24% (202) | hypothetical protein MLBr_01506 |
| M. abscessus ATCC 19977 | MAB_1026c | - | 2e-60 | 43.73% (327) | hypothetical protein MAB_1026c |
| M. marinum M | MMAR_2839 | - | 5e-33 | 46.63% (163) | immunogenic protein Mpt63 |
| M. avium 104 | MAV_3737 | - | 5e-30 | 37.19% (199) | hypothetical protein MAV_3737 |
| M. thermoresistible (build 8) | TH_4151 | - | 3e-28 | 43.05% (151) | PUTATIVE putative FHA domain containing protein |
| M. ulcerans Agy99 | MUL_2071 | - | 2e-17 | 36.89% (122) | hypothetical protein MUL_2071 |
| M. vanbaalenii PYR-1 | Mvan_5241 | - | 3e-61 | 46.67% (330) | FHA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1515|M.gilvum_PYR-GCK MKFKPALVAAATAAAA-------TAVALGGAATASADTEVQWLGQPGELV
Mvan_5241|M.vanbaalenii_PYR-1 MKFKPTVAAIITTAAA-------AAVGVVGAGSASADAEVQYLGQPGELV
MAB_1026c|M.abscessus_ATCC_199 MKIN-VPITAAVAAAA-------AAAGLALMPTAGADTT---LGQQGRLT
Mb1961c|M.bovis_AF2122/97 MKLTTMIKTAVAVVAM------AAIATFAAPVALAAYPITGKLGSELTMT
Rv1926c|M.tuberculosis_H37Rv MKLTTMIKTAVAVVAM------AAIATFAAPVALAAYPITGKLGSELTMT
MMAR_2839|M.marinum_M MKLTTMIKTAVAVVAI------ATIATITAPIAFAAYPITGKFGSELKMT
MSMEG_0828|M.smegmatis_MC2_155 MKISQLTIAAAAALAISGAAGTAGMATAFAEAAQAAQVSANPLGSQARLE
TH_4151|M.thermoresistible__bu --MNSKILAAPVVLAT------AAGLALATAAPAPARPGVADFGATQHLH
MAV_3737|M.avium_104 MKVTKNAVLTAAAAGG-----IAAASVFAATPAVAAP-NIQGFGVSEQLV
MUL_2071|M.ulcerans_Agy99 MEFIATTMKTAVGAAA-----IAAASVFGAASASAAPPTIQGFGTSERLV
MLBr_01506|M.leprae_Br4923 MKTGGFVTSAWNLPKG-LVAVVTASTAAFGLCQNAAADPANPYGTPPNPT
* *
Mflv_1515|M.gilvum_PYR-GCK N--GTVVQHWTVSHLKPSTDTIP-YQPVGTLWEATASDEAVAGNVTPIIS
Mvan_5241|M.vanbaalenii_PYR-1 N--GSVIQHWTVTGLKPSSDVIP-YRPVGTLWEATATDEAIAGTVTPIVS
MAB_1026c|M.abscessus_ATCC_199 N--GDVVQAWTISDLKVSTDQLP-YQPKGTLWEATATDEAIQGSVIPIVA
Mb1961c|M.bovis_AF2122/97 DTVGQVVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVS
Rv1926c|M.tuberculosis_H37Rv DTVGQVVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVS
MMAR_2839|M.marinum_M DSVGQVVLGWTVSDLKSSSDVIPGYPVAGQVWEATATVNAISGPVTPAIS
MSMEG_0828|M.smegmatis_MC2_155 N--GDVVQAWTISDLKPSSDPIP-YAVQGTLWEATATDEAVSGSVIPIVS
TH_4151|M.thermoresistible__bu D--GGVTIAYTLEELEPSDDVVSNVALQGRLWEVSVTVEAVEGAATPVIP
MAV_3737|M.avium_104 D--GPLVTDYTVSNLQPSNVSIPGYTPKGTLYQADISVRSDGGVVTPMVH
MUL_2071|M.ulcerans_Agy99 D--GPMVTSYTVGNLQLSDVTIAGYLPQGQLYSADVTGRSVTGTITPLVS
MLBr_01506|M.leprae_Br4923 QQLPGLPALAQLSPIVQQAANNPQQATQLLMEAVSALTQNPTAPIASKNL
: : : : . . : . . . .
Mflv_1515|M.gilvum_PYR-GCK NLNARAKNGDTYRVLFGVATTQGVNPAPLAQGHKTSGKIYFDVTGEAPDS
Mvan_5241|M.vanbaalenii_PYR-1 NLNARAENGDTYRVLFGVATEQGVNPSTLAQGQKTTGKIYFDVTGQQPDS
MAB_1026c|M.abscessus_ATCC_199 NFNAKANDGETYRVLYGVASAQGVNPGTLSQGEKTTGKIYFDVTGANPET
Mb1961c|M.bovis_AF2122/97 QFNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTI
Rv1926c|M.tuberculosis_H37Rv QFNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTI
MMAR_2839|M.marinum_M QFNARTADGVNYRVLWQASGPNTISGATIPQGASSTGKIYFDVTGPAPTI
MSMEG_0828|M.smegmatis_MC2_155 NLNARAANGENYRVLFQVATPQGVNPSTLAPGQKTTGKVYFDVTGEAPTT
TH_4151|M.thermoresistible__bu FFNARSADGQNYRALFTAVGEEALSGATLGQGQETEGNIYFDVTGAPPTE
MAV_3737|M.avium_104 DFIARGPNGQNYRVIDNVAVPNGLSPAPIPQGTESTGTLYFDVTGAPPNG
MUL_2071|M.ulcerans_Agy99 SFSARAANGDTYGVVNEVPAPGGLNPAPILQGNSQSGVLYF---------
MLBr_01506|M.leprae_Br4923 ATSVSQFMQEPNNPNPGASALDIPTSGVPAPAANGITPLDVVLVPHLPSA
. . . . . . : .
Mflv_1515|M.gilvum_PYR-GCK VFYSTGDAEELLWLQAPPPATGSGTSGSTSGSSSSGASSAP--SAAAETT
Mvan_5241|M.vanbaalenii_PYR-1 VFYSDGGSEVLLWLEAPP-APATGSAG--SGASGYGSEASP--SAAADTA
MAB_1026c|M.abscessus_ATCC_199 VTYTSGDEDLLTWKAAPAAAPAQRSGGS-TQSHGSTPAPAT--STAPTTA
Mb1961c|M.bovis_AF2122/97 VAMNNGMEDLLIWEP-----------------------------------
Rv1926c|M.tuberculosis_H37Rv VAMNNGMEDLLIWEP-----------------------------------
MMAR_2839|M.marinum_M VAMNNGMEDLMIWGP-----------------------------------
MSMEG_0828|M.smegmatis_MC2_155 VVYNDGERDLLAWSQTAASTTSPRPAATGSGTSASTPARTAPVTTAPASN
TH_4151|M.thermoresistible__bu VVYNDAVQDRLIWR------------------------------------
MAV_3737|M.avium_104 VVYNDGMQDVLMWTSNVPSSAPGAPNSPAPGAPNSPAPGAPPAPAAHT--
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01506|M.leprae_Br4923 GAEPGAQAHLPTGIDPVHAAGPATAATPTPGSPTNRTAAPPTPVASPAPT
Mflv_1515|M.gilvum_PYR-GCK APETPAS---------------TPAAEPAAVGSATPASVPSGSSGTPLPE
Mvan_5241|M.vanbaalenii_PYR-1 TPETPGT---------------TPAAETPTSVVPTPVAAPAGSSGTPLPE
MAB_1026c|M.abscessus_ATCC_199 TPAPAAVPAGSQGTPLPAGSQGTPVDEQAPAATPTPTVAPVTATPTPAPA
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2839|M.marinum_M --------------------------------------------------
MSMEG_0828|M.smegmatis_MC2_155 TPATELVPESPAVAPTGAAPAAAPGAGAAATDIPGSTVPPLAEDAADEAL
TH_4151|M.thermoresistible__bu --------------------------------------------------
MAV_3737|M.avium_104 --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01506|M.leprae_Br4923 TPELPATTPGFGPDAPPTQDFIYPSISTNCLADGSSSIATALSVAGPAKI
Mflv_1515|M.gilvum_PYR-GCK --------------------GSSGTPLP---EGSSGTPLPEGSS-----G
Mvan_5241|M.vanbaalenii_PYR-1 --------------------GSSGTPLP---EGSSGTPLPAGAAPVEAGP
MAB_1026c|M.abscessus_ATCC_199 TPTP----------------GAEGTPLNS--TAVPASPAPATATP----A
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2839|M.marinum_M --------------------------------------------------
MSMEG_0828|M.smegmatis_MC2_155 AEELTEDLPDELSQDSVTPGESVGTPLPAAVQQAPAAPAPGQPAPAAPGA
TH_4151|M.thermoresistible__bu --------------------------------------------------
MAV_3737|M.avium_104 --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01506|M.leprae_Br4923 PLPGPG------PGQAAYVFTAVGTPGPADVQKLPLNVTWVNLTTGKSGS
Mflv_1515|M.gilvum_PYR-GCK TPLPANAAPPAEAAP-APVPAAA--------TPAPAAPTTTVA-----VP
Mvan_5241|M.vanbaalenii_PYR-1 APVPAGVAPAPHGSSGTPLPAGAPAVEGVQPAPAPGAPTTTVV-----VP
MAB_1026c|M.abscessus_ATCC_199 VPVPEGAAPQTGTPPVAAVPGVP-AVPASDSVPHGQRAAGSQG-----TP
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2839|M.marinum_M --------------------------------------------------
MSMEG_0828|M.smegmatis_MC2_155 QDIPAAPAGEVPAAPVTPAPAAPVDGSTTPTVPAGSDAPLTAGGIPTLVP
TH_4151|M.thermoresistible__bu --------------------------------------------------
MAV_3737|M.avium_104 --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01506|M.leprae_Br4923 ATLKPRPDINPEGPTTLTVIADTGSGSIMSTIFGQVTTKEKQCQFMPTIG
Mflv_1515|M.gilvum_PYR-GCK APPA-----
Mvan_5241|M.vanbaalenii_PYR-1 APPA-----
MAB_1026c|M.abscessus_ATCC_199 VSTEG----
Mb1961c|M.bovis_AF2122/97 ---------
Rv1926c|M.tuberculosis_H37Rv ---------
MMAR_2839|M.marinum_M ---------
MSMEG_0828|M.smegmatis_MC2_155 AANPGAPTP
TH_4151|M.thermoresistible__bu ---------
MAV_3737|M.avium_104 ---------
MUL_2071|M.ulcerans_Agy99 ---------
MLBr_01506|M.leprae_Br4923 STVVP----