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VKFKPTVAAIITTAAAAAVGVVGAGSASADAEVQYLGQPGELVNGSVIQHWTVTGLKPSSDVIPYRPVGT LWEATATDEAIAGTVTPIVSNLNARAENGDTYRVLFGVATEQGVNPSTLAQGQKTTGKIYFDVTGQQPDS VFYSDGGSEVLLWLEAPPAPATGSAGSGASGYGSEASPSAAADTATPETPGTTPAAETPTSVVPTPVAAP AGSSGTPLPEGSSGTPLPEGSSGTPLPAGAAPVEAGPAPVPAGVAPAPHGSSGTPLPAGAPAVEGVQPAP APGAPTTTVVVPAPPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5241 | - | - | 100% (296) | FHA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2552 | - | 1e-10 | 34.36% (195) | hypothetical protein Mvan_2552 |
| M. vanbaalenii PYR-1 | Mvan_0085 | - | 1e-10 | 26.52% (313) | hypothetical protein Mvan_0085 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1961c | mpt63 | 3e-24 | 43.23% (155) | immunogenic protein MPT63 (antigen MPT63/MPB63) (16 KD |
| M. gilvum PYR-GCK | Mflv_1515 | - | 1e-108 | 66.33% (300) | FHA domain-containing protein |
| M. tuberculosis H37Rv | Rv1926c | mpt63 | 3e-24 | 43.23% (155) | immunogenic protein MPT63 (antigen MPT63/MPB63) (16 kDa |
| M. leprae Br4923 | MLBr_00568 | - | 1e-06 | 32.69% (156) | hypothetical protein MLBr_00568 |
| M. abscessus ATCC 19977 | MAB_1026c | - | 1e-68 | 49.83% (289) | hypothetical protein MAB_1026c |
| M. marinum M | MMAR_1823 | - | 2e-27 | 44.14% (145) | hypothetical protein MMAR_1823 |
| M. avium 104 | MAV_3737 | - | 2e-31 | 40.33% (181) | hypothetical protein MAV_3737 |
| M. smegmatis MC2 155 | MSMEG_5412 | - | 4e-63 | 47.00% (300) | immunogenic protein MPT63 |
| M. thermoresistible (build 8) | TH_4151 | - | 2e-24 | 39.19% (148) | PUTATIVE putative FHA domain containing protein |
| M. ulcerans Agy99 | MUL_2071 | - | 2e-19 | 40.62% (128) | hypothetical protein MUL_2071 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5241|M.vanbaalenii_PYR-1 --MKFKPTVAAIITTAAAAAVGVVGAGSASADAEV----QYLGQPGELVN
Mflv_1515|M.gilvum_PYR-GCK --MKFKPALVAAATAAAATAVALGGAATASADTEV----QWLGQPGELVN
MAB_1026c|M.abscessus_ATCC_199 --MKIN-VPITAAVAAAAAAAGLALMPTAGADTT-------LGQQGRLTN
Mb1961c|M.bovis_AF2122/97 --MKLTTMIKTAVAVVAMAAIATFAAPVALAAYP---ITGKLGSELTMTD
Rv1926c|M.tuberculosis_H37Rv --MKLTTMIKTAVAVVAMAAIATFAAPVALAAYP---ITGKLGSELTMTD
TH_4151|M.thermoresistible__bu ----MNSKILAAPVVLATAAGLALATAAPAPARP---GVADFGATQHLHD
MSMEG_5412|M.smegmatis_MC2_155 MNALKITNLSTAVAAAAVAAAAILGTAPAAFGDASAVTTSTLGSAAKLNN
MMAR_1823|M.marinum_M --------MKTAVGAAAIAAASVFGAASASAAPP---TIQGFGTSERLVD
MUL_2071|M.ulcerans_Agy99 -MEFIATTMKTAVGAAAIAAASVFGAASASAAPP---TIQGFGTSERLVD
MAV_3737|M.avium_104 -MKVTKNAVLTAAAAGGIAAASVFAATPAVAAP----NIQGFGVSEQLVD
MLBr_00568|M.leprae_Br4923 --MKVFDRFNTAILVSAGLCGAALAFSPSAAAAPLSMPTGGPTCIEQMAG
: . . . . : .
Mvan_5241|M.vanbaalenii_PYR-1 --GSVIQHWTVTGLKPSSDVIP-YRPVGTLWEATATDEAIAGTVTPIVSN
Mflv_1515|M.gilvum_PYR-GCK --GTVVQHWTVSHLKPSTDTIP-YQPVGTLWEATASDEAVAGNVTPIISN
MAB_1026c|M.abscessus_ATCC_199 --GDVVQAWTISDLKVSTDQLP-YQPKGTLWEATATDEAIQGSVIPIVAN
Mb1961c|M.bovis_AF2122/97 TVGQVVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVSQ
Rv1926c|M.tuberculosis_H37Rv TVGQVVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVSQ
TH_4151|M.thermoresistible__bu --GGVTIAYTLEELEPSDDVVSNVALQGRLWEVSVTVEAVEGAATPVIPF
MSMEG_5412|M.smegmatis_MC2_155 --GDVVQAWTVTDLKPSSDTIP-YEVRGKLWEVTATDEAVQGNVTPIVSN
MMAR_1823|M.marinum_M --GPMVTSYTVGNLQLSDVTIAGYLPQGQLYSADVTARSVTGTITPLVSS
MUL_2071|M.ulcerans_Agy99 --GPMVTSYTVGNLQLSDVTIAGYLPQGQLYSADVTGRSVTGTITPLVSS
MAV_3737|M.avium_104 --GPLVTDYTVSNLQPSNVSIPGYTPKGTLYQADISVRSDGGVVTPMVHD
MLBr_00568|M.leprae_Br4923 -LGAVPAAVPAVLPGPVAGAVPSVPVVPSGGFPPVVPPGGFPPVVPPGGF
* : :. . *
Mvan_5241|M.vanbaalenii_PYR-1 LNARAENGDTYRVLFGVATEQGVNPSTLAQGQKTTGKIYFDVTGQQPDSV
Mflv_1515|M.gilvum_PYR-GCK LNARAKNGDTYRVLFGVATTQGVNPAPLAQGHKTSGKIYFDVTGEAPDSV
MAB_1026c|M.abscessus_ATCC_199 FNAKANDGETYRVLYGVASAQGVNPGTLSQGEKTTGKIYFDVTGANPETV
Mb1961c|M.bovis_AF2122/97 FNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTIV
Rv1926c|M.tuberculosis_H37Rv FNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTIV
TH_4151|M.thermoresistible__bu FNARSADGQNYRALFTAVGEEALSGATLGQGQETEGNIYFDVTGAPPTEV
MSMEG_5412|M.smegmatis_MC2_155 FNVRAADGTNYRALFQVATPQGVNPSTIPQGEKASGKIYFDVTGPEPTTV
MMAR_1823|M.marinum_M FNARAANGDTYGVVNEVPAPGGLNPAPILQGNSQSGVLYFDVTGPPPNGV
MUL_2071|M.ulcerans_Agy99 FSARAANGDTYGVVNEVPAPGGLNPAPILQGNSQSGVLYF----------
MAV_3737|M.avium_104 FIARGPNGQNYRVIDNVAVPNGLSPAPIPQGTESTGTLYFDVTGAPPNGV
MLBr_00568|M.leprae_Br4923 LPVVPPGG-----FPPVVPPGGFPPVVPPGVAPAVGPLLAEDSAALGSGI
: . .* . . . * :
Mvan_5241|M.vanbaalenii_PYR-1 FYSDGGSEVLLWLEAPP-APATGSAG--SGASGYGSEASPSAAADTATPE
Mflv_1515|M.gilvum_PYR-GCK FYSTGDAEELLWLQAPPPATGSGTSGSTSGSSSSGASSAPSAAAETTAPE
MAB_1026c|M.abscessus_ATCC_199 TYTSGDEDLLTWKAAPAAAPAQRSGGS-TQSHGSTPAPATSTAPTTATPA
Mb1961c|M.bovis_AF2122/97 AMNNGMEDLLIWEP------------------------------------
Rv1926c|M.tuberculosis_H37Rv AMNNGMEDLLIWEP------------------------------------
TH_4151|M.thermoresistible__bu VYNDAVQDRLIWR-------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 VYNAGGKDLLVWDKPAASATAPSGTGQSRPATASSPATAAPTAAAEAESE
MMAR_1823|M.marinum_M VYNDGVQDVLIWTSNV----------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MAV_3737|M.avium_104 VYNDGMQDVLMWTSNVPSS-APGAPNSPAPGAPNSPAPGAPPAPAAHT--
MLBr_00568|M.leprae_Br4923 LAGKGVPTASPQAALSGLVVLPGPPASVEAPPAAAPVVAAATPLLCCGEA
Mvan_5241|M.vanbaalenii_PYR-1 TPGT---------------TPAAETPTSVVPTPVAAPAGSSGTPLPE---
Mflv_1515|M.gilvum_PYR-GCK TPAS---------------TPAAEPAAVGSATPASVPSGSSGTPLPE---
MAB_1026c|M.abscessus_ATCC_199 PAAVPAGSQGTPLPAGSQGTPVDEQAPAATPTPTVAPVTATPTPAPATPT
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
TH_4151|M.thermoresistible__bu --------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 AATDAETEATPAPAAASTAEGGTEATPAGAGSRATDLPAATAAEAETEAT
MMAR_1823|M.marinum_M --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MAV_3737|M.avium_104 --------------------------------------------------
MLBr_00568|M.leprae_Br4923 APPVR---------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 -GSSGTPLP-EGSSGTPLPAGAAPVEA------------GPAPVPAGVAP
Mflv_1515|M.gilvum_PYR-GCK -GSSGTPLP-EGSSGTPLPEGSS-----------------GTPLPANAAP
MAB_1026c|M.abscessus_ATCC_199 PGAEGTPLNSTAVPASPAPATATP----------------AVPVPEGAAP
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
TH_4151|M.thermoresistible__bu --------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 ATDAETTPVTEETPAAPAPEGTTPVSLGTPAAEGTPAVEGAPAGASAGNV
MMAR_1823|M.marinum_M --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MAV_3737|M.avium_104 --------------------------------------------------
MLBr_00568|M.leprae_Br4923 --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 APHGSSGTPLPAGAPAVEGVQPAPAPGAPTTTVVVPAPPA---------
Mflv_1515|M.gilvum_PYR-GCK PAEAAP-APVPAAA--------TPAPAAPTTTVAVPAPPA---------
MAB_1026c|M.abscessus_ATCC_199 QTGTPPVAAVPGVP-AVPASDSVPHGQRAAGSQGTPVSTEG--------
Mb1961c|M.bovis_AF2122/97 -------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv -------------------------------------------------
TH_4151|M.thermoresistible__bu -------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 ATAVPPAAPAEGAPAEVADPALVPAGVQPTTTVPAPAPTTAPVSHGPAA
MMAR_1823|M.marinum_M -------------------------------------------------
MUL_2071|M.ulcerans_Agy99 -------------------------------------------------
MAV_3737|M.avium_104 -------------------------------------------------
MLBr_00568|M.leprae_Br4923 -------------------------------------------------