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KVTKNAVLTAAAAGGIAAASVFAATPAVAAPNIQGFGVSEQLVDGPLVTDYTVSNLQPSNVSIPGYTPKG TLYQADISVRSDGGVVTPMVHDFIARGPNGQNYRVIDNVAVPNGLSPAPIPQGTESTGTLYFDVTGAPPN GVVYNDGMQDVLMWTSNVPSSAPGAPNSPAPGAPNSPAPGAPPAPAAHT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3737 | - | - | 100% (190) | hypothetical protein MAV_3737 |
| M. avium 104 | MAV_2859 | - | 7e-08 | 55.00% (40) | ModD protein |
| M. avium 104 | MAV_1722 | - | 2e-05 | 63.64% (33) | secreted protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1961c | mpt63 | 2e-26 | 43.67% (158) | immunogenic protein MPT63 (antigen MPT63/MPB63) (16 KD |
| M. gilvum PYR-GCK | Mflv_1515 | - | 4e-31 | 38.17% (186) | FHA domain-containing protein |
| M. tuberculosis H37Rv | Rv1926c | mpt63 | 2e-26 | 43.67% (158) | immunogenic protein MPT63 (antigen MPT63/MPB63) (16 kDa |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1026c | - | 6e-27 | 37.50% (192) | hypothetical protein MAB_1026c |
| M. marinum M | MMAR_1823 | - | 2e-50 | 63.58% (151) | hypothetical protein MMAR_1823 |
| M. smegmatis MC2 155 | MSMEG_5412 | - | 9e-31 | 38.02% (192) | immunogenic protein MPT63 |
| M. thermoresistible (build 8) | TH_4151 | - | 1e-27 | 40.27% (149) | PUTATIVE putative FHA domain containing protein |
| M. ulcerans Agy99 | MUL_2071 | - | 2e-35 | 58.40% (125) | hypothetical protein MUL_2071 |
| M. vanbaalenii PYR-1 | Mvan_5241 | - | 1e-31 | 40.33% (181) | FHA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1515|M.gilvum_PYR-GCK ---MKFKPALVAAATAAAATAVALGGAATAS---ADTEVQWLGQPGELVN
Mvan_5241|M.vanbaalenii_PYR-1 ---MKFKPTVAAIITTAAAAAVGVVGAGSAS---ADAEVQYLGQPGELVN
MAB_1026c|M.abscessus_ATCC_199 ---MKIN-VPITAAVAAAAAAAGLALMPTAG---ADTT---LGQQGRLTN
TH_4151|M.thermoresistible__bu ---MNSK-ILAAPVVLATAAGLALATAAPAP---ARPGVADFGATQHLHD
Mb1961c|M.bovis_AF2122/97 --MKLTTMIKTAVAVVAMAAIATF-AAPVAL--AAYPITGKLGSELTMTD
Rv1926c|M.tuberculosis_H37Rv --MKLTTMIKTAVAVVAMAAIATF-AAPVAL--AAYPITGKLGSELTMTD
MSMEG_5412|M.smegmatis_MC2_155 MNALKITNLSTAVAAAAVAAAAILGTAPAAFGDASAVTTSTLGSAAKLNN
MMAR_1823|M.marinum_M ---------MKTAVGAAAIAAASVFGAASAS--AAPPTIQGFGTSERLVD
MUL_2071|M.ulcerans_Agy99 --MEFIATTMKTAVGAAAIAAASVFGAASAS--AAPPTIQGFGTSERLVD
MAV_3737|M.avium_104 --MKVTKNAVLTAAAAGGIAAASVFAATPAV--AAP-NIQGFGVSEQLVD
: . : . * : :* : :
Mflv_1515|M.gilvum_PYR-GCK --GTVVQHWTVSHLKPSTDTIP-YQPVGTLWEATASDEAVAGNVTPIISN
Mvan_5241|M.vanbaalenii_PYR-1 --GSVIQHWTVTGLKPSSDVIP-YRPVGTLWEATATDEAIAGTVTPIVSN
MAB_1026c|M.abscessus_ATCC_199 --GDVVQAWTISDLKVSTDQLP-YQPKGTLWEATATDEAIQGSVIPIVAN
TH_4151|M.thermoresistible__bu --GGVTIAYTLEELEPSDDVVSNVALQGRLWEVSVTVEAVEGAATPVIPF
Mb1961c|M.bovis_AF2122/97 TVGQVVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVSQ
Rv1926c|M.tuberculosis_H37Rv TVGQVVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVSQ
MSMEG_5412|M.smegmatis_MC2_155 --GDVVQAWTVTDLKPSSDTIP-YEVRGKLWEVTATDEAVQGNVTPIVSN
MMAR_1823|M.marinum_M --GPMVTSYTVGNLQLSDVTIAGYLPQGQLYSADVTARSVTGTITPLVSS
MUL_2071|M.ulcerans_Agy99 --GPMVTSYTVGNLQLSDVTIAGYLPQGQLYSADVTGRSVTGTITPLVSS
MAV_3737|M.avium_104 --GPLVTDYTVSNLQPSNVSIPGYTPKGTLYQADISVRSDGGVVTPMVHD
* : :.: *: * :. * ::.. : .: * * :
Mflv_1515|M.gilvum_PYR-GCK LNARAKNGDTYRVLFGVATTQGVNPAPLAQGHKTSGKIYFDVTGEAPDSV
Mvan_5241|M.vanbaalenii_PYR-1 LNARAENGDTYRVLFGVATEQGVNPSTLAQGQKTTGKIYFDVTGQQPDSV
MAB_1026c|M.abscessus_ATCC_199 FNAKANDGETYRVLYGVASAQGVNPGTLSQGEKTTGKIYFDVTGANPETV
TH_4151|M.thermoresistible__bu FNARSADGQNYRALFTAVGEEALSGATLGQGQETEGNIYFDVTGAPPTEV
Mb1961c|M.bovis_AF2122/97 FNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTIV
Rv1926c|M.tuberculosis_H37Rv FNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTIV
MSMEG_5412|M.smegmatis_MC2_155 FNVRAADGTNYRALFQVATPQGVNPSTIPQGEKASGKIYFDVTGPEPTTV
MMAR_1823|M.marinum_M FNARAANGDTYGVVNEVPAPGGLNPAPILQGNSQSGVLYFDVTGPPPNGV
MUL_2071|M.ulcerans_Agy99 FSARAANGDTYGVVNEVPAPGGLNPAPILQGNSQSGVLYF----------
MAV_3737|M.avium_104 FIARGPNGQNYRVIDNVAVPNGLSPAPIPQGTESTGTLYFDVTGAPPNGV
: .: :* .* .: . :. ..: ** . * :**
Mflv_1515|M.gilvum_PYR-GCK FYSTGDAEELLWLQAPPPATGSGTSGSTSGSSSSGASSAPSAAAETTAPE
Mvan_5241|M.vanbaalenii_PYR-1 FYSDGGSEVLLWLEAPP-APATGSAG--SGASGYGSEASPSAAADTATPE
MAB_1026c|M.abscessus_ATCC_199 TYTSGDEDLLTWKAAPAAAPAQRSGGS-TQSHGSTPAPATSTAPTTATPA
TH_4151|M.thermoresistible__bu VYNDAVQDRLIWR-------------------------------------
Mb1961c|M.bovis_AF2122/97 AMNNGMEDLLIWEP------------------------------------
Rv1926c|M.tuberculosis_H37Rv AMNNGMEDLLIWEP------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 VYNAGGKDLLVWDKPAASATAPSGTGQSRPATASSPATAAPTAAAEAESE
MMAR_1823|M.marinum_M VYNDGVQDVLIWTSNV----------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MAV_3737|M.avium_104 VYNDGMQDVLMWTSNVPSSAPGAPNSPAPGAPNSPAPGAPPAPAAHT---
Mflv_1515|M.gilvum_PYR-GCK TPAS---------------TPAAEPAAVGSATPASVPSGSSGTPLPE---
Mvan_5241|M.vanbaalenii_PYR-1 TPGT---------------TPAAETPTSVVPTPVAAPAGSSGTPLPE---
MAB_1026c|M.abscessus_ATCC_199 PAAVPAGSQGTPLPAGSQGTPVDEQAPAATPTPTVAPVTATPTPAPATPT
TH_4151|M.thermoresistible__bu --------------------------------------------------
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 AATDAETEATPAPAAASTAEGGTEATPAGAGSRATDLPAATAAEAETEAT
MMAR_1823|M.marinum_M --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MAV_3737|M.avium_104 --------------------------------------------------
Mflv_1515|M.gilvum_PYR-GCK -GSSGTPLP-EGSSGTPLPEGSS----------GTPLPANAAP-------
Mvan_5241|M.vanbaalenii_PYR-1 -GSSGTPLP-EGSSGTPLPAGAAPVEA-----GPAPVPAGVAP-------
MAB_1026c|M.abscessus_ATCC_199 PGAEGTPLNSTAVPASPAPATATP---------AVPVPEGAAP-------
TH_4151|M.thermoresistible__bu --------------------------------------------------
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 ATDAETTPVTEETPAAPAPEGTTPVSLGTPAAEGTPAVEGAPAGASAGNV
MMAR_1823|M.marinum_M --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MAV_3737|M.avium_104 --------------------------------------------------
Mflv_1515|M.gilvum_PYR-GCK PAEAAP-APVPAAA--------TPAPAAPTTTVAVPAPPA---------
Mvan_5241|M.vanbaalenii_PYR-1 APHGSSGTPLPAGAPAVEGVQPAPAPGAPTTTVVVPAPPA---------
MAB_1026c|M.abscessus_ATCC_199 QTGTPPVAAVPGVP-AVPASDSVPHGQRAAGSQGTPVSTEG--------
TH_4151|M.thermoresistible__bu -------------------------------------------------
Mb1961c|M.bovis_AF2122/97 -------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv -------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 ATAVPPAAPAEGAPAEVADPALVPAGVQPTTTVPAPAPTTAPVSHGPAA
MMAR_1823|M.marinum_M -------------------------------------------------
MUL_2071|M.ulcerans_Agy99 -------------------------------------------------
MAV_3737|M.avium_104 -------------------------------------------------