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MKLTTMIKTAVAVVAMAAIATFAAPVALAAYPITGKLGSELTMTDTVGQVVLGWKVSDLKSSTAVIPGYP VAGQVWEATATVNAIRGSVTPAVSQFNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGP SPTIVAMNNGMEDLLIWEP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1961c | mpt63 | - | 100% (159) | immunogenic protein MPT63 (antigen MPT63/MPB63) (16 KD immunoprotective extracellular protein) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2854 | - | 4e-28 | 44.44% (126) | hypothetical protein Mflv_2854 |
| M. tuberculosis H37Rv | Rv1926c | mpt63 | 1e-87 | 100.00% (159) | immunogenic protein MPT63 (antigen MPT63/MPB63) (16 kDa |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4857 | - | 2e-30 | 45.27% (148) | hypothetical protein MAB_4857 |
| M. marinum M | MMAR_2839 | - | 3e-76 | 85.53% (159) | immunogenic protein Mpt63 |
| M. avium 104 | MAV_3737 | - | 1e-26 | 43.67% (158) | hypothetical protein MAV_3737 |
| M. smegmatis MC2 155 | MSMEG_5412 | - | 6e-37 | 51.59% (157) | immunogenic protein MPT63 |
| M. thermoresistible (build 8) | TH_4151 | - | 1e-27 | 38.71% (155) | PUTATIVE putative FHA domain containing protein |
| M. ulcerans Agy99 | MUL_2071 | - | 8e-18 | 36.09% (133) | hypothetical protein MUL_2071 |
| M. vanbaalenii PYR-1 | Mvan_5241 | - | 2e-24 | 41.61% (149) | FHA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1961c|M.bovis_AF2122/97 ---MKLT--TMIKTAVAVVAMAAIATFAAPVALAAYPITGKLGSELTMTD
Rv1926c|M.tuberculosis_H37Rv ---MKLT--TMIKTAVAVVAMAAIATFAAPVALAAYPITGKLGSELTMTD
MMAR_2839|M.marinum_M ---MKLT--TMIKTAVAVVAIATIATITAPIAFAAYPITGKFGSELKMTD
MSMEG_5412|M.smegmatis_MC2_155 MNALKITNLSTAVAAAAVAAAAILGTAPAAFGDASAVTTSTLGSAAKLNN
Mvan_5241|M.vanbaalenii_PYR-1 ---MKFK--PTVAAIITTAAAAAVGVVGAGSASADAEVQY-LGQPGELVN
MAV_3737|M.avium_104 ---MKVTK-NAVLTAAAAGGIAAASVFAATPAVAAP-NIQGFGVSEQLVD
MUL_2071|M.ulcerans_Agy99 ---MEFIA-TTMKTAVGAAAIAAASVFGAASASAAPPTIQGFGTSERLVD
TH_4151|M.thermoresistible__bu ------MNSKILAAPVVLATAAGLALATAAPAPARP-GVADFGATQHLHD
Mflv_2854|M.gilvum_PYR-GCK -----------------------------------MPCGHQFGSPQQLTD
MAB_4857|M.abscessus_ATCC_1997 ------MRVLRMIMMAAAAVLAMLAVSVPLANAAKNDCPHKMGSHQRLSD
:* : :
Mb1961c|M.bovis_AF2122/97 TVGQVVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVSQ
Rv1926c|M.tuberculosis_H37Rv TVGQVVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVSQ
MMAR_2839|M.marinum_M SVGQVVLGWTVSDLKSSSDVIPGYPVAGQVWEATATVNAISGPVTPAISQ
MSMEG_5412|M.smegmatis_MC2_155 --GDVVQAWTVTDLKPSSDTIP-YEVRGKLWEVTATDEAVQGNVTPIVSN
Mvan_5241|M.vanbaalenii_PYR-1 --GSVIQHWTVTGLKPSSDVIP-YRPVGTLWEATATDEAIAGTVTPIVSN
MAV_3737|M.avium_104 --GPLVTDYTVSNLQPSNVSIPGYTPKGTLYQADISVRSDGGVVTPMVHD
MUL_2071|M.ulcerans_Agy99 --GPMVTSYTVGNLQLSDVTIAGYLPQGQLYSADVTGRSVTGTITPLVSS
TH_4151|M.thermoresistible__bu --GGVTIAYTLEELEPSDDVVSNVALQGRLWEVSVTVEAVEGAATPVIPF
Mflv_2854|M.gilvum_PYR-GCK AGGAVVQEWVISDLRESSVALPGYTARGQVWEASATVRAVTGTVTPIIPN
MAB_4857|M.abscessus_ATCC_1997 ADGAVVQEWTISGLRKSTDGVPGYPVAGQLWEATASVHAVTGSVTPLIPN
* : : : *. * :. * ::.. : .: * ** :
Mb1961c|M.bovis_AF2122/97 FNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTIV
Rv1926c|M.tuberculosis_H37Rv FNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTIV
MMAR_2839|M.marinum_M FNARTADGVNYRVLWQASGPNTISGATIPQGASSTGKIYFDVTGPAPTIV
MSMEG_5412|M.smegmatis_MC2_155 FNVRAADGTNYRALFQVATPQGVNPSTIPQGEKASGKIYFDVTGPEPTTV
Mvan_5241|M.vanbaalenii_PYR-1 LNARAENGDTYRVLFGVATEQGVNPSTLAQGQKTTGKIYFDVTGQQPDSV
MAV_3737|M.avium_104 FIARGPNGQNYRVIDNVAVPNGLSPAPIPQGTESTGTLYFDVTGAPPNGV
MUL_2071|M.ulcerans_Agy99 FSARAANGDTYGVVNEVPAPGGLNPAPILQGNSQSGVLYF----------
TH_4151|M.thermoresistible__bu FNARSADGQNYRALFTAVGEEALSGATLGQGQETEGNIYFDVTGAPPTEV
Mflv_2854|M.gilvum_PYR-GCK LYTVTAAGQRYPVLWQIASPQGLPATTLGEGQASSGAIYFDAVGPQPMAV
MAB_4857|M.abscessus_ATCC_1997 LGAVSGSQERYPALWQVASPYGIPAATIAQGHTATGKVYFDVTGEAPAMV
: . * .: : :.: :* * :**
Mb1961c|M.bovis_AF2122/97 AMNNG--MEDLLIWEP----------------------------------
Rv1926c|M.tuberculosis_H37Rv AMNNG--MEDLLIWEP----------------------------------
MMAR_2839|M.marinum_M AMNNG--MEDLMIWGP----------------------------------
MSMEG_5412|M.smegmatis_MC2_155 VYNAG--GKDLLVW-DKPAASATAPSGTGQSRPATASSPATAAPTAAAEA
Mvan_5241|M.vanbaalenii_PYR-1 FYSDG--GSEVLLWLEAPPAPATGSAGSGASGYGSEASPSAAADTATPET
MAV_3737|M.avium_104 VYNDG--MQDVLMWTSNVPSSAPGAPNSPAPGAPNSPAPGAPPAPAAHT-
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
TH_4151|M.thermoresistible__bu VYNDA--VQDRLIWR-----------------------------------
Mflv_2854|M.gilvum_PYR-GCK VYDNG--TPTQLFWCCTGSM--MMMPME-----KCPMCADMQRA------
MAB_4857|M.abscessus_ATCC_1997 TYQGGGGSMAALMWCDEAAMKTMMAAMKSAPDADCPCCADMPAAKGGDDC
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2839|M.marinum_M --------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 ES-EAATDAETEATPAPAAASTAEGGTEATPAGAGSRATDLPAATAAEAE
Mvan_5241|M.vanbaalenii_PYR-1 PGTTPAAETPTSVVPTPVAAP---AGSSGTPLPEGSSGTPLPEG-SSGTP
MAV_3737|M.avium_104 --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
TH_4151|M.thermoresistible__bu --------------------------------------------------
Mflv_2854|M.gilvum_PYR-GCK CPHRPGGM------------------------------------------
MAB_4857|M.abscessus_ATCC_1997 CADKP---------------------------------------------
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2839|M.marinum_M --------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 TEATATDAETTPVTEETPAAPAPEGTTPVSLGTPAAEGTPAVEGAPAGAS
Mvan_5241|M.vanbaalenii_PYR-1 LPAGAAPVEAGPAPVPAGVAPAPHGSS----GTPLPAGAPAVEGVQP---
MAV_3737|M.avium_104 --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
TH_4151|M.thermoresistible__bu --------------------------------------------------
Mflv_2854|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4857|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2839|M.marinum_M --------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 AGNVATAVPPAAPAEGAPAEVADPALVPAGVQPTTTVPAPAPTTAPVSHG
Mvan_5241|M.vanbaalenii_PYR-1 -----------APAPGAP---------------TTTVVVPAPPA------
MAV_3737|M.avium_104 --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
TH_4151|M.thermoresistible__bu --------------------------------------------------
Mflv_2854|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4857|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1961c|M.bovis_AF2122/97 ---
Rv1926c|M.tuberculosis_H37Rv ---
MMAR_2839|M.marinum_M ---
MSMEG_5412|M.smegmatis_MC2_155 PAA
Mvan_5241|M.vanbaalenii_PYR-1 ---
MAV_3737|M.avium_104 ---
MUL_2071|M.ulcerans_Agy99 ---
TH_4151|M.thermoresistible__bu ---
Mflv_2854|M.gilvum_PYR-GCK ---
MAB_4857|M.abscessus_ATCC_1997 ---