For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
KINVPITAAVAAAAAAAGLALMPTAGADTTLGQQGRLTNGDVVQAWTISDLKVSTDQLPYQPKGTLWEAT ATDEAIQGSVIPIVANFNAKANDGETYRVLYGVASAQGVNPGTLSQGEKTTGKIYFDVTGANPETVTYTS GDEDLLTWKAAPAAAPAQRSGGSTQSHGSTPAPATSTAPTTATPAPAAVPAGSQGTPLPAGSQGTPVDEQ APAATPTPTVAPVTATPTPAPATPTPGAEGTPLNSTAVPASPAPATATPAVPVPEGAAPQTGTPPVAAVP GVPAVPASDSVPHGQRAAGSQGTPVSTEG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1026c | - | - | 100% (310) | hypothetical protein MAB_1026c |
| M. abscessus ATCC 19977 | MAB_4857 | - | 2e-25 | 38.97% (195) | hypothetical protein MAB_4857 |
| M. abscessus ATCC 19977 | MAB_0462c | - | 2e-21 | 34.09% (220) | hypothetical protein MAB_0462c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1961c | mpt63 | 8e-30 | 47.02% (151) | immunogenic protein MPT63 (antigen MPT63/MPB63) (16 KD |
| M. gilvum PYR-GCK | Mflv_1515 | - | 2e-68 | 51.79% (280) | FHA domain-containing protein |
| M. tuberculosis H37Rv | Rv1926c | mpt63 | 8e-30 | 47.02% (151) | immunogenic protein MPT63 (antigen MPT63/MPB63) (16 kDa |
| M. leprae Br4923 | MLBr_02591 | mce1C | 7e-07 | 31.79% (151) | putative secreted protein |
| M. marinum M | MMAR_2839 | - | 9e-27 | 42.00% (150) | immunogenic protein Mpt63 |
| M. avium 104 | MAV_3737 | - | 1e-26 | 37.50% (192) | hypothetical protein MAV_3737 |
| M. smegmatis MC2 155 | MSMEG_5412 | - | 1e-62 | 45.12% (328) | immunogenic protein MPT63 |
| M. thermoresistible (build 8) | TH_4151 | - | 4e-24 | 38.31% (154) | PUTATIVE putative FHA domain containing protein |
| M. ulcerans Agy99 | MUL_2071 | - | 4e-15 | 34.96% (123) | hypothetical protein MUL_2071 |
| M. vanbaalenii PYR-1 | Mvan_5241 | - | 2e-68 | 49.83% (289) | FHA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1515|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1026c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2839|M.marinum_M --------------------------------------------------
TH_4151|M.thermoresistible__bu --------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3737|M.avium_104 --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 MRTLELPNRLRSGLIGVLVVLLIIGVGQSFTSVPILFARPSYYGQFTDTG
Mflv_1515|M.gilvum_PYR-GCK -----------------------------MKFKP---ALVAAATAAAATA
Mvan_5241|M.vanbaalenii_PYR-1 -----------------------------MKFKP---TVAAIITTAAAAA
MAB_1026c|M.abscessus_ATCC_199 -----------------------------MKIN----VPITAAVAAAAAA
Mb1961c|M.bovis_AF2122/97 -----------------------------MKLT--TMIKTAVAVVAMAAI
Rv1926c|M.tuberculosis_H37Rv -----------------------------MKLT--TMIKTAVAVVAMAAI
MMAR_2839|M.marinum_M -----------------------------MKLT--TMIKTAVAVVAIATI
TH_4151|M.thermoresistible__bu -------------------------------MN--SKILAAPVVLATAAG
MSMEG_5412|M.smegmatis_MC2_155 --------------------------MNALKITNLSTAVAAAAVAAAAIL
MAV_3737|M.avium_104 -----------------------------MKVTK-NAVLTAAAAGGIAAA
MUL_2071|M.ulcerans_Agy99 -----------------------------MEFIA-TTMKTAVGAAAIAAA
MLBr_02591|M.leprae_Br4923 GLNKGDKVRIAGMDVGKVEALKIDGDHVVIKFSIGTNRIGTASRLGIRTD
. : .
Mflv_1515|M.gilvum_PYR-GCK VALGGAATASADTEVQWLGQPGELVN----------------GTVVQHWT
Mvan_5241|M.vanbaalenii_PYR-1 VGVVGAGSASADAEVQYLGQPGELVN----------------GSVIQHWT
MAB_1026c|M.abscessus_ATCC_199 AGLALMPTAGADTT---LGQQGRLTN----------------GDVVQAWT
Mb1961c|M.bovis_AF2122/97 ATFAAPVALAAYPITGKLGSELTMTDTV--------------GQVVLGWK
Rv1926c|M.tuberculosis_H37Rv ATFAAPVALAAYPITGKLGSELTMTDTV--------------GQVVLGWK
MMAR_2839|M.marinum_M ATITAPIAFAAYPITGKFGSELKMTDSV--------------GQVVLGWT
TH_4151|M.thermoresistible__bu LALATAAPAPARPGVADFGATQHLHD----------------GGVTIAYT
MSMEG_5412|M.smegmatis_MC2_155 GTAPAAFGDASAVTTSTLGSAAKLNN----------------GDVVQAWT
MAV_3737|M.avium_104 SVFAATPAVAAP-NIQGFGVSEQLVD----------------GPLVTDYT
MUL_2071|M.ulcerans_Agy99 SVFGAASASAAPPTIQGFGTSERLVD----------------GPMVTSYT
MLBr_02591|M.leprae_Br4923 TVLGKKVLEVETRGTQLLRPGDSLPLGQSTTPYQSYDAFFDATKVASGWN
: : : :.
Mflv_1515|M.gilvum_PYR-GCK VSHLKPSTDTIP--------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 VTGLKPSSDVIP--------------------------------------
MAB_1026c|M.abscessus_ATCC_199 ISDLKVSTDQLP--------------------------------------
Mb1961c|M.bovis_AF2122/97 VSDLKSSTAVIPG-------------------------------------
Rv1926c|M.tuberculosis_H37Rv VSDLKSSTAVIPG-------------------------------------
MMAR_2839|M.marinum_M VSDLKSSSDVIPG-------------------------------------
TH_4151|M.thermoresistible__bu LEELEPSDDVVSN-------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 VTDLKPSSDTIP--------------------------------------
MAV_3737|M.avium_104 VSNLQPSNVSIPG-------------------------------------
MUL_2071|M.ulcerans_Agy99 VGNLQLSDVTIAG-------------------------------------
MLBr_02591|M.leprae_Br4923 IDTIKQSLKVVSETIDQTYPHLSAALDGVAKFSDTIGARDKEIKHLIAQA
: :: * :.
Mflv_1515|M.gilvum_PYR-GCK YQPVGTLWEATASDEAVAGNVTPIISNLNARAKNGDTYR---VLFGVATT
Mvan_5241|M.vanbaalenii_PYR-1 YRPVGTLWEATATDEAIAGTVTPIVSNLNARAENGDTYR---VLFGVATE
MAB_1026c|M.abscessus_ATCC_199 YQPKGTLWEATATDEAIQGSVIPIVANFNAKANDGETYR---VLYGVASA
Mb1961c|M.bovis_AF2122/97 YPVAGQVWEATATVNAIRGSVTPAVSQFNARTADGINYR---VLWQAAGP
Rv1926c|M.tuberculosis_H37Rv YPVAGQVWEATATVNAIRGSVTPAVSQFNARTADGINYR---VLWQAAGP
MMAR_2839|M.marinum_M YPVAGQVWEATATVNAISGPVTPAISQFNARTADGVNYR---VLWQASGP
TH_4151|M.thermoresistible__bu VALQGRLWEVSVTVEAVEGAATPVIPFFNARSADGQNYR---ALFTAVGE
MSMEG_5412|M.smegmatis_MC2_155 YEVRGKLWEVTATDEAVQGNVTPIVSNFNVRAADGTNYR---ALFQVATP
MAV_3737|M.avium_104 YTPKGTLYQADISVRSDGGVVTPMVHDFIARGPNGQNYR---VIDNVAVP
MUL_2071|M.ulcerans_Agy99 YLPQGQLYSADVTGRSVTGTITPLVSSFSARAANGDTYG---VVNEVPAP
MLBr_02591|M.leprae_Br4923 NQVASVLGDRGAQVDRLLVNTKTLIAAFNERGRAVDALLGNVAAFAAQVQ
. : . . : : : . .
Mflv_1515|M.gilvum_PYR-GCK QGVN---------------PAPLAQGHKTSGKIYFDVTGEAP--------
Mvan_5241|M.vanbaalenii_PYR-1 QGVN---------------PSTLAQGQKTTGKIYFDVTGQQP--------
MAB_1026c|M.abscessus_ATCC_199 QGVN---------------PGTLSQGEKTTGKIYFDVTGANP--------
Mb1961c|M.bovis_AF2122/97 DTIS---------------GATIPQGEQSTGKIYFDVTGPSP--------
Rv1926c|M.tuberculosis_H37Rv DTIS---------------GATIPQGEQSTGKIYFDVTGPSP--------
MMAR_2839|M.marinum_M NTIS---------------GATIPQGASSTGKIYFDVTGPAP--------
TH_4151|M.thermoresistible__bu EALS---------------GATLGQGQETEGNIYFDVTGAPP--------
MSMEG_5412|M.smegmatis_MC2_155 QGVN---------------PSTIPQGEKASGKIYFDVTGPEP--------
MAV_3737|M.avium_104 NGLS---------------PAPIPQGTESTGTLYFDVTGAPP--------
MUL_2071|M.ulcerans_Agy99 GGLN---------------PAPILQGNSQSGVLYF---------------
MLBr_02591|M.leprae_Br4923 RLINDNPNLNHVLEQLHQLSGILVQHKDDLANTLIQVAAFLPSLNEAIGS
:. . : * . . :
Mflv_1515|M.gilvum_PYR-GCK ---------------------DSVFYSTGDAEELLWLQAPPPATGSGTSG
Mvan_5241|M.vanbaalenii_PYR-1 ---------------------DSVFYSDGGSEVLLWLEAPP-APATGSAG
MAB_1026c|M.abscessus_ATCC_199 ---------------------ETVTYTSGDEDLLTWKAAPAAAPAQRSGG
Mb1961c|M.bovis_AF2122/97 ---------------------TIVAMNNGMEDLLIWEP------------
Rv1926c|M.tuberculosis_H37Rv ---------------------TIVAMNNGMEDLLIWEP------------
MMAR_2839|M.marinum_M ---------------------TIVAMNNGMEDLMIWGP------------
TH_4151|M.thermoresistible__bu ---------------------TEVVYNDAVQDRLIWR-------------
MSMEG_5412|M.smegmatis_MC2_155 ---------------------TTVVYNAGGKDLLVWDKPAASATAPSGTG
MAV_3737|M.avium_104 ---------------------NGVVYNDGMQDVLMWTS-NVPSSAPGAPN
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 GPFFKVVLHNLAPYQILQPWVDAAFKKRGIDPENFWRSAGLPEFRFPDPN
Mflv_1515|M.gilvum_PYR-GCK STSGSSSSGASSAPSAAAETTAPETPAS---------------TPAAEPA
Mvan_5241|M.vanbaalenii_PYR-1 --SGASGYGSEASPSAAADTATPETPGT---------------TPAAETP
MAB_1026c|M.abscessus_ATCC_199 S-TQSHGSTPAPATSTAPTTATPAPAAVPAGSQGTPLPAGSQGTPVDEQA
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2839|M.marinum_M --------------------------------------------------
TH_4151|M.thermoresistible__bu --------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 QSRPATASSPATAAPTAAAEAESEAATDAETEATPAPAAASTAEGGTEAT
MAV_3737|M.avium_104 SPAPGAPNSPAPGAPPAPAAHT----------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 GTRFPNGAPPPAPPVLEGTPENPGPAVPPGSPCSYTPAHPGGNNTIGDEM
Mflv_1515|M.gilvum_PYR-GCK AVGSATPASVPSGSSGTPLPE----GSSGTPLP-EGSSGTPLPEGSS---
Mvan_5241|M.vanbaalenii_PYR-1 TSVVPTPVAAPAGSSGTPLPE----GSSGTPLP-EGSSGTPLPAGAAPVE
MAB_1026c|M.abscessus_ATCC_199 PAATPTPTVAPVTATPTPAPATPTPGAEGTPLNSTAVPASPAPATATP--
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2839|M.marinum_M --------------------------------------------------
TH_4151|M.thermoresistible__bu --------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 PAGAGSRATDLPAATAAEAETEATATDAETTPVTEETPAAPAPEGTTPVS
MAV_3737|M.avium_104 --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 GLPRPWNPLPCAGATAGPYGGPAFPAPIDVQTSPPNPDGLPLLPGIAIAG
Mflv_1515|M.gilvum_PYR-GCK --------------GTPLPANAAPPAEAAP-APVPAAA--------TPAP
Mvan_5241|M.vanbaalenii_PYR-1 A------------GPAPVPAGVAPAPHGSSGTPLPAGAPAVEGVQPAPAP
MAB_1026c|M.abscessus_ATCC_199 --------------AVPVPEGAAPQTGTPPVAAVPGVP-AVPASDSVPHG
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2839|M.marinum_M --------------------------------------------------
TH_4151|M.thermoresistible__bu --------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 LGTPAAEGTPAVEGAPAGASAGNVATAVPPAAPAEGAPAEVADPALVPAG
MAV_3737|M.avium_104 --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 RPGDPAPNVPG--TPVPLPPNAPPGARTEQLAPAAPAQDSSAPHEPREQL
Mflv_1515|M.gilvum_PYR-GCK AAPTTTVAVPAPPA---------
Mvan_5241|M.vanbaalenii_PYR-1 GAPTTTVVVPAPPA---------
MAB_1026c|M.abscessus_ATCC_199 QRAAGSQGTPVSTEG--------
Mb1961c|M.bovis_AF2122/97 -----------------------
Rv1926c|M.tuberculosis_H37Rv -----------------------
MMAR_2839|M.marinum_M -----------------------
TH_4151|M.thermoresistible__bu -----------------------
MSMEG_5412|M.smegmatis_MC2_155 VQPTTTVPAPAPTTAPVSHGPAA
MAV_3737|M.avium_104 -----------------------
MUL_2071|M.ulcerans_Agy99 -----------------------
MLBr_02591|M.leprae_Br4923 SAPLINPGGTGGSGGAGGSRN--