For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AMAEPAPPPCVNADGTPCSDIGTAGPGGATGQIPGGPGGTAGPGGASGAIPGGPGGAAGPDGATGSIPGG PAGTAGPDGATGVIPGGPGGTAGPGGASGCIPNVGCATIPAP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5543 | - | - | 100% (113) | hypothetical protein MSMEG_5543 |
| M. smegmatis MC2 155 | MSMEG_3545 | - | 1e-13 | 47.92% (96) | hypothetical protein MSMEG_3545 |
| M. smegmatis MC2 155 | MSMEG_5926 | - | 1e-09 | 36.00% (100) | putative secreted protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2517c | PE_PGRS43b | 9e-15 | 48.19% (83) | hypothetical protein Mb2517c |
| M. gilvum PYR-GCK | Mflv_1054 | - | 3e-48 | 74.11% (112) | hypothetical protein Mflv_1054 |
| M. tuberculosis H37Rv | Rv2490c | PE_PGRS43 | 9e-15 | 48.19% (83) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01556 | infB | 2e-07 | 35.04% (117) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_3220 | - | 7e-27 | 58.43% (89) | hypothetical protein MAB_3220 |
| M. marinum M | MMAR_2823 | - | 1e-24 | 47.17% (106) | PE-PGRS family protein |
| M. avium 104 | MAV_2780 | - | 1e-25 | 52.63% (95) | hypothetical protein MAV_2780 |
| M. thermoresistible (build 8) | TH_3810 | - | 4e-06 | 38.37% (86) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4367 | - | 2e-15 | 48.86% (88) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 3e-12 | 46.43% (84) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 --------------------------------------------------
Rv2490c|M.tuberculosis_H37Rv MSYVIATPEMMATAAFDLARIGSQVSAASAVAAMPTTEVVAAGADEVSAG
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 --------------------------------------------------
Rv2490c|M.tuberculosis_H37Rv IAALFSAHAQEYQALSAQAAAFHDQFVHTLTAAARWYTATEIANAAAMRV
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 --------------------------------------------------
Rv2490c|M.tuberculosis_H37Rv VLGAVNAPTQTLLGRPLIGDGAHGTAPGQPGGAGGLLFGNGGNGAAGAVG
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 --------------------------------------------------
Rv2490c|M.tuberculosis_H37Rv QVGGAGGAAGLFGIGGAGGAGGAGAPGGTGGTGGWLAGGGGVGGMGGAGG
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 --------------------------------------------------
Rv2490c|M.tuberculosis_H37Rv GAGGAGGNAGLFGNGGAGGAGGAGGGAGGAGGNAGWFGHGGAGGVGGVGA
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 --------------------------------------------------
Rv2490c|M.tuberculosis_H37Rv AGANGATPGQDGAAGVAGSDDGAGGDGLAGSDGGDGGAGGVGGNGGRGGW
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 --------------------------------------------------
Rv2490c|M.tuberculosis_H37Rv LLGNGGAGGVGGVGGAGGAGAAGGAGGAGATGINGPAGISAAGGDGGAGG
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 --------------------------------------------------
Rv2490c|M.tuberculosis_H37Rv NGGAGGNGGVGGAGGAGGSAGLLGYVGRAGDGGAGGGGGLGGAPGDGGAG
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 --------------------------------------------------
Rv2490c|M.tuberculosis_H37Rv GNGGSWLAAGDGGAGGHGGDPGLGGAGGAGGASGGAGARAGANGLAAGND
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 --------------------------------------------------
Rv2490c|M.tuberculosis_H37Rv GPVSGGNGGKGGNGAHAPVAGGHGGNGGAGGNGGLVGDGGAGGHGGDGAA
MUL_4367|M.ulcerans_Agy99 --------------------------------------------MSFVSV
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 ------------------------------------------------MA
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 ------MTAIFLGSSGTPGEDGGNGGAGGAGGAGGAHAGDGGAGGAGGNG
Rv2490c|M.tuberculosis_H37Rv GAGYADMTAIFLGSSGTPGEDGGNGGAGGAGGAGGAHAGDGGAGGAGGNG
MUL_4367|M.ulcerans_Agy99 GPGLLEAAARDLAGLGAGLREANLAAAGATVGVLPAAGDEVSAAIAELFG
Mvan_1264|M.vanbaalenii_PYR-1 --------MMFLAPPGGP------GPISAAIQLTSTGSEATEPWYVVSFG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 GKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRESFG
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 GAGGAGGNGAHGFNAVLVSDGGNGGDGGAGGRGGDGGAGGAGGDAPAGRA
Rv2490c|M.tuberculosis_H37Rv GAGGAGGNGAHGFNAVLVSDGGNGGDGGAGGRGGDGGAGGAGGDAPAGRA
MUL_4367|M.ulcerans_Agy99 GFG--REYQAMGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQELEQQ
Mvan_1264|M.vanbaalenii_PYR-1 GSGAPTPNNLAASLVDLS-----------GTSCG----------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 GIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAPVQ
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 GSQGVGGDGGAGGAGGAPGNGGSGGRGDMAFKDGDGGAGGDGGDP-GAGG
Rv2490c|M.tuberculosis_H37Rv GSQGVGGDGGAGGAGGAPGNGGSGGRGDMAFKDGDGGAGGDGGDP-GAGG
MUL_4367|M.ulcerans_Agy99 ALGVVNAPSMALFGRPSIGNGVDG-------VAGTGQAGGAGGILWGNGG
Mvan_1264|M.vanbaalenii_PYR-1 ----------------LICNGQDG-------------TGQNGGILFGNGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 VDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPH
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 KGG-AGGAGATEGVTGATGATVHSGGNGGKGGNGADATVAGANGGKGGAG
Rv2490c|M.tuberculosis_H37Rv KGG-AGGAGATEGVTGATGATVHSGGNGGKGGNGADATVAGANGGKGGAG
MUL_4367|M.ulcerans_Agy99 NGG-LGAAGANGGAGGSAG-LIGTGGVGGAGGVGA----AGMTGGSGGAG
Mvan_1264|M.vanbaalenii_PYR-1 SGWNSEIAGVSGGNGGNAGLFGGNGGNGGNG----------LGSGDGGNG
TH_3810|M.thermoresistible__bu ------------------------------------------VDGDGGSG
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 PGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAPRPSA
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 GNGGLVGDGGAGGDGGSGAAGANGANVGEDGADGTLSGQPGEGSEANGGQ
Rv2490c|M.tuberculosis_H37Rv GNGGLVGDGGAGGDGGSGAAGANGANVGEDGADGTLSGQPGEGSEANGGQ
MUL_4367|M.ulcerans_Agy99 GGGGWLWG--AGGSG--GAAGAGGS----GGSGGWLWGNAGQTAGAGVG-
Mvan_1264|M.vanbaalenii_PYR-1 GDAGLFSLFGRGGNGGNGGVGIAGA-----------TGAVGAPGVAGAT-
TH_3810|M.thermoresistible__bu GRTGLFSKLSRGGDG-----------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 SPSSMSPRPGGAVGGGGPRPPRTGVP----------------RPGGGRPG
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 GGVGGGGAGGAGGDGGAGSSALGSGGNGGRGDAGQAGGAGGAGGAGGAGG
Rv2490c|M.tuberculosis_H37Rv GGVGGGGAGGAGGDGGAGSSALGSGGNGGRGDAGQAGGAGGAGGAGGAGG
MUL_4367|M.ulcerans_Agy99 ---GAGGAGGAGDAGDQGVSGVAPGEAGAVGFAGGAGGAGGAGGNG-VGG
Mvan_1264|M.vanbaalenii_PYR-1 ---GATGVT-SNVTGGNGADAVGYGATGAAGAAGAAGAAGKAGAVG-SAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 APVGGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGGRPGQRGG
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK -----------------------------------------MRYKTSVLG
Mb2517c|M.bovis_AF2122/97 SVSGDGGPGGKGGAGGAGGAGASGG-----GGGKGASGADSAEAVGGAGG
Rv2490c|M.tuberculosis_H37Rv SVSGDGGPGGKGGAGGAGGAGASGG-----GGGKGASGADSAEAVGGAGG
MUL_4367|M.ulcerans_Agy99 GVNGAGGAGGAGGVGGGGGAGASGVGAGVAGGDGGTGGAGGAAGVGGAAG
Mvan_1264|M.vanbaalenii_PYR-1 TAGSAGAPGVWGNAGLPGAAGAAGG-----------AGAIGTAGVAGAAG
TH_3810|M.thermoresistible__bu ---GDGGLGGNGGHGGG-------------------TGIISLLSLAGNGG
MMAR_2823|M.marinum_M -----------------------------------------MRSQARTTF
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --MQDSRQRKKQDQRSPTHLTREHP----------------MKTRTVKPA
MLBr_01556|M.leprae_Br4923 AAGAFGRPGGAPRRGRKSKRQKRQE-----------YDSMQAPVVGGVRL
MSMEG_5543|M.smegmatis_MC2_155 -------------------MAMAEPAPPPCVNADG---------------
Mflv_1054|M.gilvum_PYR-GCK TFGPMLFAGAAATAIATAPLTFAQPAPPPCFNADG---------------
Mb2517c|M.bovis_AF2122/97 KGGDGGVGGVGGDGGPGGDGGAGGAAPAGQVGSHG--VGGVGGDGGLGGA
Rv2490c|M.tuberculosis_H37Rv KGGDGGVGGVGGDGGPGGDGGAGGAAPAGQVGSHG--VGGVGGDGGLGGA
MUL_4367|M.ulcerans_Agy99 TGGTGGAAGVAGTGGDGGDGGAGGAGSDASLAGQAGFAGGSGGAGGVGGS
Mvan_1264|M.vanbaalenii_PYR-1 TAGATGGTGVGGNGGAGQAGGIGGTGAAGAAGQAG-------TAGETGVT
TH_3810|M.thermoresistible__bu NGGN-GYRTTDNNALDGGHGGNGGNVGFFSLFNLG---------------
MMAR_2823|M.marinum_M AVFGGGAMLVLA--VACGGGENKGPSSTTPTTTPT---------------
MAV_2780|M.avium_104 -MFGGAAMLVLA--VGCGGGHKGGPS-TTSTTTPT---------------
MAB_3220|M.abscessus_ATCC_1997 KVFAGCAIALGAALAGCGTNNDGGPTSTSTTTTTT---------------
MLBr_01556|M.leprae_Br4923 PHGNGETIRLARGASLSDFAEKIDANPAALVQALFN--------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 GGNGGDGGHGSDGGDGGDGGDPGAG----GLGGLGGDSGNGTRAASGVDA
Rv2490c|M.tuberculosis_H37Rv GGNGGDGGHGSDGGDGGDGGDPGAG----GLGGLGGDSGNGTRAASGVDA
MUL_4367|M.ulcerans_Agy99 AGAGGVNGSGGDGGAGAAGGAGGASATVAGSGGVGGDGGAGGAAGGGVGA
Mvan_1264|M.vanbaalenii_PYR-1 GGVGGIGGQGTEGGTGGVGG----------VGGVGATGG-----------
TH_3810|M.thermoresistible__bu -GAGGWGGSGVDG-------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 SDHGPGSGGNGGNGGNGAQASVAGGAGGNGGDGGNAGRVGDGGAGGNGGD
Rv2490c|M.tuberculosis_H37Rv SDHGPGSGGNGGNGGNGAQASVAGGAGGNGGDGGNAGRVGDGGAGGNGGD
MUL_4367|M.ulcerans_Agy99 ASLG----GDGGHAG-------AGGAGGEGLSGG----FNTGAAGGIGGA
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------AGGVGGKGIQGG------QGLQGGQGGD
TH_3810|M.thermoresistible__bu ----------------------VDVVGGNP-------------------D
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 ------------------------------TPCSDIGTAGPGGATG----
Mflv_1054|M.gilvum_PYR-GCK ------------------------------TPCTALGTAGPGGAAG----
Mb2517c|M.bovis_AF2122/97 GAAGANGANSGAPGSDALALGQPGGNGGQGDAGQAGGAGGAGGAG---GS
Rv2490c|M.tuberculosis_H37Rv GAAGANGANSGAPGSDALALGQPGGNGGQGDAGQAGGAGGAGGAGGAGGS
MUL_4367|M.ulcerans_Agy99 GGAGGTGGDSGGVGGVNGDGGAGGGGGRGGDGGSSTSTSGVGGAG---GA
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGDATSMG-EAGATGGKGGNGGNGGRGSLFGRGGNAGNG-----
TH_3810|M.thermoresistible__bu GGTPGAHGESHTPGVYTDRQGE------DGEDGTGTGIGGRGGNG-----
MMAR_2823|M.marinum_M -----------------------------TTVPSS--PSSSPATE-----
MAV_2780|M.avium_104 -----------------------------TTPSTSVVPSTTPGG------
MAB_3220|M.abscessus_ATCC_1997 -----------------------------TTTTTTITPAPSGAPE-----
MLBr_01556|M.leprae_Br4923 ---------LGEMVTATQSVGDETLELLGSEMNYNVQVVSPEDEDR----
MSMEG_5543|M.smegmatis_MC2_155 ------------------------------------QIPGGPGGTAGPGG
Mflv_1054|M.gilvum_PYR-GCK ------------------------------------AIPGGPAGEAGPGG
Mb2517c|M.bovis_AF2122/97 VSGDGGAGGNGGAGGNGGVGASGGAGARGANGIDSIGGTGGAGGGGGDG-
Rv2490c|M.tuberculosis_H37Rv VSGDGGAGGNGGAGGNGGVGASGGAGARGANGIDSIGGTGGAGGGGGDG-
MUL_4367|M.ulcerans_Agy99 GGNGGNAGFGVSAGGTGGSAGDGGAGG-GAGGVDGVGGASGNGGAAGAG-
Mvan_1264|M.vanbaalenii_PYR-1 --------------GNGGTGGNGGNGG--------TGGTGGNGGTGGTG-
TH_3810|M.thermoresistible__bu ------------------------------------GSSSGTHPMAEDGE
MMAR_2823|M.marinum_M ----------------------------------SSPAPGGPSGTGGPEG
MAV_2780|M.avium_104 ----------------------------------GGTVPGGPTGGGGPGG
MAB_3220|M.abscessus_ATCC_1997 ----------------------------------GTPAPG-PTGGGGPDG
MLBr_01556|M.leprae_Br4923 --------------------------------ELLEPFDLTYGEDQGDED
MSMEG_5543|M.smegmatis_MC2_155 ASGAIPGGPGGAAGPDGATGSIP-------------GGPAGTAGPDGATG
Mflv_1054|M.gilvum_PYR-GCK ASGAIPGGPAGEAGPGGASGAIP-------------GGPAGEAGPGGVSG
Mb2517c|M.bovis_AF2122/97 GAGGVG-GHGGDGGVGGAAPSG----TVGSHGTGGVGGDGGLGGAGGVGG
Rv2490c|M.tuberculosis_H37Rv GAGGVG-GHGGDGGVGGAAPSG----TVGSHGTGGVGGDGGLGGAGGVGG
MUL_4367|M.ulcerans_Agy99 GAGGSGIGAGIDGGAGGAGGTGGAAGFPGGGGTTGAWGTGGAGGAGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGIG-GAGSTGGTGGTGGTG---------GTGGTGGTGGTGGTGGTGG
TH_3810|M.thermoresistible__bu HVKALDGRPGLDGGNGSHGGNG---------GHGGRGGFLGIGGSGGWGG
MMAR_2823|M.marinum_M GGGGVPGGPTGSGGPGGGGGSIP-------------GGPTGGGGPGGGGG
MAV_2780|M.avium_104 GGGSIPGGPTGGGGPGGGGGSIP-------------GGPTGGGGPGGGGG
MAB_3220|M.abscessus_ATCC_1997 GSGAIPGGPTGGGGPEGGSGSIP-------------GGPTGGGGPEGGGG
MLBr_01556|M.leprae_Br4923 ELQVRPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVGV
. * *.
MSMEG_5543|M.smegmatis_MC2_155 --------------VIPGGPGGTAGPGGAS--------------------
Mflv_1054|M.gilvum_PYR-GCK S-------------TNPGGVSGAAGPDGVS--------------------
Mb2517c|M.bovis_AF2122/97 AGGNGGIGITVGGAGGAGGNGGDPGAGGRGGLGGDSGNGTSAANGVDASK
Rv2490c|M.tuberculosis_H37Rv AGGNGGIGITVGGAGGAGGNGGDPGAGGRGGLGGDSGNGTSAANGVDASK
MUL_4367|M.ulcerans_Agy99 AGDHGGVGVNPGDSGTAGWAGGAGGAGGAG--------GSAAFNGVNGAG
Mvan_1264|M.vanbaalenii_PYR-1 TGGKGGT----GGTGGDGGTGGTGGTGGTG--------------------
TH_3810|M.thermoresistible__bu HGGNG------GDTDADGGNGGDGGNGGSA--------------------
MMAR_2823|M.marinum_M T--------------IPGVGGGGGGPGGGG--------------------
MAV_2780|M.avium_104 S--------------IPGVGGGGGGPGGGG--------------------
MAB_3220|M.abscessus_ATCC_1997 H--------------IPGVGGGHGGPGGGG--------------------
MLBr_01556|M.leprae_Br4923 DLDGSERLITFIDTPGHEAFTAMRARGAKAT-------------------
. . .. .
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 HGPLTGGDGGVGGNGAKAAAAGGDGGQGGDGGNAGLFGDGGAGGDGADGT
Rv2490c|M.tuberculosis_H37Rv HGPLTGGDGGVGGNGAKAAAAGGDGGQGGDGGNAGLFGDGGAGGDGADGT
MUL_4367|M.ulcerans_Agy99 GAGGNGGAGGGGGAGASGIGAGVAGGDGGTGGTGGAAGTGGAAGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 ---GTGGTGGTGGTGGTGGAGDGLGGTGGTGGTGGFGGQGGQGGTGGTG-
TH_3810|M.thermoresistible__bu -------------------------GRGGTGGLRGVFGING---------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 ----------------DIAILVVAADDGVMPQTVEAINHAQAADVPIVVA
MSMEG_5543|M.smegmatis_MC2_155 ----------GCIPNVGCATIPAP--------------------------
Mflv_1054|M.gilvum_PYR-GCK ----------GCIPNVGCATIPVG--------------------------
Mb2517c|M.bovis_AF2122/97 AAEALG--GDGGAGGAGGKGGDAGDIGDGGDGGKGGDGAHGALGGLTVAG
Rv2490c|M.tuberculosis_H37Rv AAEALG--GDGGAGGAGGKGGDAGDIGDGGDGGKGGDGAHGALGGLTVAG
MUL_4367|M.ulcerans_Agy99 AAGAAGSAGDGGAGGAGGAGDDGSAGVVSGDPGTAG--KAGGAGGAGGVG
Mvan_1264|M.vanbaalenii_PYR-1 --------GQGGLGGVGGTGGTGGTGGTGGQGGTGG------TGGTGGTG
TH_3810|M.thermoresistible__bu --------GNGRAG-LGGRGXXXXGGGVG----------------AAVRS
MMAR_2823|M.marinum_M ----------GCIGNI-CGSYP----------------------------
MAV_2780|M.avium_104 ----------GCVGNV-CGAYP----------------------------
MAB_3220|M.abscessus_ATCC_1997 ----------GCVDNVGCVSIP----------------------------
MLBr_01556|M.leprae_Br4923 VNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLE
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 GNGGAGGAGGAGGAGGAFLGDGGNGGAGGQGGAGRGGSPGGG-GGVGGHG
Rv2490c|M.tuberculosis_H37Rv GNGGAGGAGGAGGAGGAFLGDGGNGGAGGQGGAGRGGSPGGG-GGVGGHG
MUL_4367|M.ulcerans_Agy99 GNGVAGGVNGSGGAG----GAGGAGGTGGAGASGVPASVDGGDGGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGAGGDGGLGGLG----GFGGVGGTGGQGGQGGPGGSTGGAGGAGGQA
TH_3810|M.thermoresistible__bu GNGVFSGGGGTPSAG-----------------FGVPTTIQFPAGSCTSR-
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 AVLLTADAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLVQRGTLRIGD
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 GAGGDAGMNGGGGTGGQGGNGAAGGAGWSPDSDLKGFDGFDGGSGGAGGD
Rv2490c|M.tuberculosis_H37Rv GAGGDAGMNGGGGTGGQGGNGAAGGAGWSPDSDLKGFDGFDGGSGGAGGD
MUL_4367|M.ulcerans_Agy99 GAAGTGGSGGSAGNTGAGGAGGAGGAGGSAAS--TGVNG-DGGAGGAGGV
Mvan_1264|M.vanbaalenii_PYR-1 GVAGKGGLFGGSGSAGTAGVTGASGAS---------------GGKGAQGA
TH_3810|M.thermoresistible__bu -AVSREGIMPS--------------------------------SRAASAR
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 SVVAGDAYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPGAGDNFLVVD
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 GGAGGAGGTQTGDGGDGGAGGLGGAGGVGGNGVDGFDINETTGRDG-DGG
Rv2490c|M.tuberculosis_H37Rv GGAGGAGGTQTGDGGDGGAGGLGGAGGVGGNGVDGFDINETTGRDGGDGG
MUL_4367|M.ulcerans_Agy99 GGLGGDSAATAGGGGAGGDGGKGGAGGAGVNGVG--------------GG
Mvan_1264|M.vanbaalenii_PYR-1 TGAQGATGAQGATGATGASGAQGSAGSAG---------------------
TH_3810|M.thermoresistible__bu AGAACASSTSRSRRSFCCSRA-----------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 EDRIARQIADRRSARKRNALAARSRKRISLEDLDSALKETSQLNLILKGD
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 DGGYGGWGGAGGNGGAGGSAPAGEVGNRGVGGDGGDGGSGGDAGNGGLGG
Rv2490c|M.tuberculosis_H37Rv DGGYGGWGGAGGNGGAGGSAPAGEVGNRGVGGDGGDGGSGGDAGNGGLGG
MUL_4367|M.ulcerans_Agy99 DGGKGGTGGAGGAGGAGSDGIIPSNG--GLGGNGGNGGNGGQAFGDGVGG
Mvan_1264|M.vanbaalenii_PYR-1 --------SAGVAGSAGTTGAQGSAGTNGANGANGSQGAAGKAGATGTTG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 NAGTVEALEEALMGIQVDDEVALRVIDRGVGGITETNVNLASASDAIIIG
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 DGFTYLADFDGEPGGDGGDGGDGGWGRPGGQGGFGSTSGAHGKAGFGAPG
Rv2490c|M.tuberculosis_H37Rv DGFTYLADFDGEPGGDGGDGGDGGWGRPGGQGGFGSTSGAHGKAGFGAPG
MUL_4367|M.ulcerans_Agy99 ---------AGGIGGKGGNAAIGTIVINGGVGGAGG-SGGLGGATEDGVG
Mvan_1264|M.vanbaalenii_PYR-1 ---------ATGAAGDAGDPGSEAVDINGGAGGAGG------------AG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 FNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQL
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 GDGGDGGNGGHGGDGNGSFADAGDGGPGGNGGNGGLGGAGRDGGAPGGDG
Rv2490c|M.tuberculosis_H37Rv GDGGDGGNGGHGGDGNGSFADAGDGGPGGNGGNGGLGGAGRDGGAPGGDG
MUL_4367|M.ulcerans_Agy99 GVGCAGGAGGNGGRGDMLFTVGGSGGTGGDGG----GGGSASGSGTGGSG
Mvan_1264|M.vanbaalenii_PYR-1 GEGGEGGAGGAGGDG----SEGGAGGSGGAGG-----------SGTGGAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 GRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTS
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
Mb2517c|M.bovis_AF2122/97 GDGGTGGSGGFGAPPPRSIGGGDGGDGGRGGDGGRGAGGLTSGGVGSSGE
Rv2490c|M.tuberculosis_H37Rv GDGGTGGSGGFGAPPPRSIGGGDGGDGGRGGDGGRGAGGLTSGGVGSSGE
MUL_4367|M.ulcerans_Agy99 GTGGVGGIGGDGK------LGGFGGDGGDGGDGGFGVIGGQGGGGGFGG-
Mvan_1264|M.vanbaalenii_PYR-1 GAGGSGGSGG---------SGGAGGSGGAAGDSD----------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 LRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA-------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------
Mb2517c|M.bovis_AF2122/97 SGGSGNGRGDPGSGGSGGEGGEGGPSISVNVT
Rv2490c|M.tuberculosis_H37Rv SGGSGNGRGDPGSGGSGGEGGEGGPSISVNVT
MUL_4367|M.ulcerans_Agy99 LGGTGAG-GAPSDKGINGEPGNPG--------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------
TH_3810|M.thermoresistible__bu --------------------------------
MMAR_2823|M.marinum_M --------------------------------
MAV_2780|M.avium_104 --------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------