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M. ulcerans Agy99 MUL_4367 (-)

annotation: PE-PGRS family protein
coordinates: 4845511 - 4848744
length: 1077
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*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4367--100% (1077)PE-PGRS family protein
M. ulcerans Agy99MUL_0572-0.047.82% (918) PE-PGRS family protein
M. ulcerans Agy99MUL_3062-0.049.21% (884) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3538PE_PGRS540.049.77% (1302) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-0.047.42% (852) triple helix repeat-containing collagen
M. tuberculosis H37RvRv3514PE_PGRS570.053.25% (1232) PE-PGRS family protein
M. leprae Br4923MLBr_01183-5e-1340.22% (92) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-1e-6037.04% (459) hypothetical protein MAB_4284c
M. marinum MMMAR_5294-0.071.60% (1081) PE-PGRS family protein
M. avium 104MAV_4827-4e-2647.34% (169) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-16140.57% (1092) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-4e-4239.26% (326) PUTATIVE -
M. vanbaalenii PYR-1Mvan_1264-0.049.54% (769) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mb3538|M.bovis_AF2122/97            MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAGADEVSAR
Rv3514|M.tuberculosis_H37Rv         MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAGADEVSAR
MUL_4367|M.ulcerans_Agy99           MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGVLPAAGDEVSAA
MMAR_5294|M.marinum_M               MSFVSVAPSLLDAAARDLAGLGAGLREANLAAAGATMGVLPAAGDEVSAA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      -----------------------------------MHERLRERAGGVRKT
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------MMFLAPPGGPGPISAA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------MSIIDFILNLFRDPVEAA
MAV_4827|M.avium_104                --------------------------------MNIVLGVSMAPSSIQMVV
                                                                                      

Mb3538|M.bovis_AF2122/97            IAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYASAEA------AA
Rv3514|M.tuberculosis_H37Rv         IAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYASAEA------AA
MUL_4367|M.ulcerans_Agy99           IAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQE
MMAR_5294|M.marinum_M               IAELFGGFGREYQAVGARMALLHDDFVRALTAGGSAYGQAEALNMWPLQE
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      LSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPESPLPDLKPRWERPTTA
Mflv_5091|M.gilvum_PYR-GCK          ---------------MVTFGGGATPTPTSLGAAAVDLSGTSCGLICNGQD
Mvan_1264|M.vanbaalenii_PYR-1       IQLTSTGSEATEPWYVVSFGGSGAPTPNNLAASLVDLSGTSCGLICNGQD
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNP
MAV_4827|M.avium_104                LEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQ
                                                                                      

Mb3538|M.bovis_AF2122/97            AEQIVLGVINAPTQALLGRPLIGDGANATTPGG-AGGAGGLLFGNGGAGA
Rv3514|M.tuberculosis_H37Rv         AEQIVLGVINAPTQALLGRPLIGDGANATTPGG-AGGAGGLLFGNGGAGA
MUL_4367|M.ulcerans_Agy99           LEQQALGVVNAPSMALFGRPSIGNGVDGVAGTGQAGGAGGILWGNGGNGG
MMAR_5294|M.marinum_M               LEQQALGVVNAPSMALFGRPLIGNGVDGVAGTGQAGGAGGILWGNGGNGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      PDSETPSITQPQ-----GRDTAADPAEQQATS--TNTTDQPTSDSLGAQP
Mflv_5091|M.gilvum_PYR-GCK          GTGQNGGILFGN-----GGSGWNSDVVGMDGG--NGGNGGLFGGNGGNGG
Mvan_1264|M.vanbaalenii_PYR-1       GTGQNGGILFGN-----GGSGWNSEIAGVSGG--NGGNAGLFGGNGGNGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      IHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIAS
MAV_4827|M.avium_104                LSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMG
                                                                                      

Mb3538|M.bovis_AF2122/97            AGAPGQAGGPGGPAGLWGNGGPGGAGGSGGGTGGAGGAGGWLFGVGGAGG
Rv3514|M.tuberculosis_H37Rv         AGAPGQAGGPGGPAGLWGNGGPGGAGGSGGGTGGAGGAGGWLFGVGGAGG
MUL_4367|M.ulcerans_Agy99           LGAAGANGGAGGSAGLIGTGGVGGAGGVGA--------------------
MMAR_5294|M.marinum_M               SGAAGANGGAGGSAGLIGTGGVGGAGGVGA--------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TAQVARQVQAPATDPAPAAPSLRPISGLLS--------------------
Mflv_5091|M.gilvum_PYR-GCK          NGLGGGNGGNGGNAGAFALFGNGGNGGNGG--------------------
Mvan_1264|M.vanbaalenii_PYR-1       NGLGSGDGGNGGDAGLFSLFGRGGNGGNGG--------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GNQVMSPSGNVDSFNRGPLLDLSFGDLQFGN-------------------
MAV_4827|M.avium_104                YERTAVLLVEPDTATLAVVETSDGS-------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            VGGAGGGTGGAGGPGGLIWGGGGAGGVGGAGGGTGGAGG-----------
Rv3514|M.tuberculosis_H37Rv         VGGAGGGTGGAGGPGGLIWGGGGAGGVGGAGGGTGGAGG-----------
MUL_4367|M.ulcerans_Agy99           -AGMTGGSGGAGGGGGWLWGAGGSG-------------------------
MMAR_5294|M.marinum_M               -VGMAGGSGGAGGSGGWLWGAGGAGGVGGAGGVGAGAGGIGGHGGAGGAG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      -VVTLGTTLIPNAPT----EPADMP-------------------------
Mflv_5091|M.gilvum_PYR-GCK          -VGVVGATGAVGAPG----VAGATG-------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -VGIAGATGAVGAPG----VAGATG-------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -RDTTAIGDGAVAVGGSNSGP-----------------------------
MAV_4827|M.avium_104                IPDVYKQQIRAESYG-----------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               GVARSLLFGTGGAGGAGGVGGGGVAGVDSGTPGGAGGGGGVGGAGGAGGV
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------RAELLFGAGGAG
Rv3514|M.tuberculosis_H37Rv         --------------------------------------RAELLFGAGGAG
MUL_4367|M.ulcerans_Agy99           -------------------------------------------------G
MMAR_5294|M.marinum_M               GGGSRSLLFGAGGVGGEGASGGLGGGGGAGASGVGFDMAGGAGGDGGAGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ------------------------------------------------GV
Mflv_5091|M.gilvum_PYR-GCK          ------------------------------------------------AT
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------------------AT
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------------------------------IAS
MAV_4827|M.avium_104                -----------------------------------------------DAA
                                                                                      

Mb3538|M.bovis_AF2122/97            GAGGAGTDGGPGATGGTGGHGGVGGDGGWLAPGGAGGAGGQGGAGGAGSD
Rv3514|M.tuberculosis_H37Rv         GAG---TDGGPGATGGTGGHGGVGGDGGWLAPGGAGGAGGQGGAGGAGSD
MUL_4367|M.ulcerans_Agy99           AAGAGGSGGSGGWLWGNAGQTAGAGVGGAGGAGGAGDAGDQGVSGVAPGE
MMAR_5294|M.marinum_M               AAGAGGAGGSGGWLWGNAGQTAGAGVGGAGGAGGAGGAGDHGVSSIAPGE
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      WAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDPTQIVNWLIYQ
Mflv_5091|M.gilvum_PYR-GCK          GVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAGAVGSAGAAGEAGET
Mvan_1264|M.vanbaalenii_PYR-1       GVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAGAVGSAGTAGSAGAP
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADID
MAV_4827|M.avium_104                GQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEP
                                                                                      

Mb3538|M.bovis_AF2122/97            GGALGGTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQGGTGGAGGD
Rv3514|M.tuberculosis_H37Rv         GGALGGTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQGGTGGAGGD
MUL_4367|M.ulcerans_Agy99           AGAVGFAGGAGGAGGAGGNGVGGGVNGAGGAGGAGGVGGGGGAGASGVGA
MMAR_5294|M.marinum_M               AGAVGFAGGAGGAGGAGGNGVGGGVNGAGGVGGAGGAGGGGGAGASGVGA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      P--LHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTADNPNGGTG
Mflv_5091|M.gilvum_PYR-GCK          G--TWGNAGLPGKAGDAGGAGAVGAAGAAGTVGTAGATGGTGTGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1       G--VWGNAGLPGAAGAAGGAGAIGTAGVAGAAGTAGATGGTGVGGNGGAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      KSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHNQANIGTS
MAV_4827|M.avium_104                ETALARGAALAAANAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVD
                                                                                      

Mb3538|M.bovis_AF2122/97            GVLGGVGGTGGKGGVGGVAGLGGAGGAAG---------------------
Rv3514|M.tuberculosis_H37Rv         GVLGGVGGTGGKGGVGGVAGLGGAGGAAG---------------------
MUL_4367|M.ulcerans_Agy99           GVAGGDGGTGGAGGAAGVGGAAGTGGTG----------------------
MMAR_5294|M.marinum_M               GVAGGDGGTGGAGGAAGVGGAAGSGGVGGAAGVAGTGGDGGAGGSGGASD
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GLLFGDGGHGYDGSAAGLAGGNGG--------------------------
Mflv_5091|M.gilvum_PYR-GCK          -GVGGVGGTGAAG-AAGGAGGLGE--------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -QAGGIGGTGAAG-AAGQAGTAGE--------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      TSAGGSAAVGGNAGLAGNAGLAGN--------------------------
MAV_4827|M.avium_104                PEPGDDELAYSAVGEEDAES------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ------------------------QLFSAGGAAGAVGVG-----------
Rv3514|M.tuberculosis_H37Rv         ------------------------QLFSASGAAGNAGVGGAGGQGGDGGA
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               QGAAGVNPGEAGAVGFAGGAGGAGGAGGDSGAGGVNGSGGVGGAGGAGGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -----------------------------------------GTGGQGGAG
Rv3514|M.tuberculosis_H37Rv         GGAGADADQPGATGGTGFAGGAGGAGGAGGSSGAGGTNGSGGAGGQGGAG
MUL_4367|M.ulcerans_Agy99           --------------------------------------GAAGVAGTGGDG
MMAR_5294|M.marinum_M               GGAGASGVGAGVAGGDGGTGGAGGAAGVGGAAGSGGVGGAAGVAGTGGDG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ---------------------------------------NAGLFGNGGNG
Mflv_5091|M.gilvum_PYR-GCK          ---------------------------------------TGTTGGAGGVG
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------------------------TGVTGGVGGIG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------------AGLAGNAGLA
MAV_4827|M.avium_104                ----------------------------------------PTVVIEKLFL
                                                                                      

Mb3538|M.bovis_AF2122/97            GMGGSGADNASG--------IGADGGAGGTGGNAGAGGAGGAAGTGGTGG
Rv3514|M.tuberculosis_H37Rv         GAGGAGADNPTG--------IGGTGGDGGTGGAAGAGGAGGAAGTGGTGG
MUL_4367|M.ulcerans_Agy99           GDGGAGGAGSDASLAGQAGFAGGSGGAGGVGGSAGAGGVNGSGGDGGAGA
MMAR_5294|M.marinum_M               GDGGAGGAGSDASVAGQAGFAGGSGGAGGVGGSAGAGGVNGSGGDGGAGA
TH_3810|M.thermoresistible__bu      ----VDGD-------------GGSGGRTGLFSKLSRGGDGG---------
MSMEG_0868|M.smegmatis_MC2_155      GVGWAGLD-------------GGNGGSGGLLMGIGGAGGAGGVGADGTSA
Mflv_5091|M.gilvum_PYR-GCK          GQGTAGGT-------------GGVGGIGGAGSTGAVGGVGGKGIQGGQG-
Mvan_1264|M.vanbaalenii_PYR-1       GQGTEGGT-------------GGVGGVGGVGATGGAGGVGGKGIQGGQG-
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GNAGLAGN-------------AGLAGNAGLAGNAGLAGNAGLAGNAGLAG
MAV_4827|M.avium_104                PEDSEPRR-------------RPVLLVGSGLAVVGISAVLALEIALAIG-
                                                                                      

Mb3538|M.bovis_AF2122/97            VVGAAG----KAGIGGTGGQGGAGGAGSAG--------------TDATAT
Rv3514|M.tuberculosis_H37Rv         MIGTTG----NAGVGGAGGQGGDGGAGGAG--------------ADADQP
MUL_4367|M.ulcerans_Agy99           AGGAGGASATVAGSGGVGGDGGAGGAAG-----------------GGVGA
MMAR_5294|M.marinum_M               AGGAGGASATVAGSGGVGGDGGAGGAAG-----------------GGVGA
TH_3810|M.thermoresistible__bu      -------------DGGLGGNGGHGGGTG--------------------II
MSMEG_0868|M.smegmatis_MC2_155      H-----------VDGGTGGTGGTGGGTGGTGGIGGTGGGLFGLLGHSGST
Mflv_5091|M.gilvum_PYR-GCK          ------------LQGGKGGDGGAGGKGG-----------------DADSM
Mvan_1264|M.vanbaalenii_PYR-1       ------------LQGGQGGDGGTGGTGG-----------------DATSM
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------NAGLAGNAGLAGNAG--------------------LA
MAV_4827|M.avium_104                --------------IRTTGTVALQPTPN-----------------QHLIV
                                                                                      

Mb3538|M.bovis_AF2122/97            GATGGTGFSGGAGGAGGAGG--NTGVGGTNGSGGQGGTGGAGGAGGAGGV
Rv3514|M.tuberculosis_H37Rv         GATGGTGFAGGAGGAGGAGG--SSGAGGTNGSGGAGGTGGQGGAGGAGGA
MUL_4367|M.ulcerans_Agy99           ASLGGDGGHAGAGGAGGEGLSGGFNTGAAGGIGGAGGAGGTGGD------
MMAR_5294|M.marinum_M               AGLGGDGGHAGAGGAGGEGLSGGFNTGAAGGIGGAGGAGGTGGD------
TH_3810|M.thermoresistible__bu      SLLSLAG-NGGNGGNG---------YRTTDNNALDGGHGGNGG-------
MSMEG_0868|M.smegmatis_MC2_155      GAAGAAG-NGGDGGNGGFGYVLIAGPNVTVGSETRGGTGGAGG-------
Mflv_5091|M.gilvum_PYR-GCK          GSAGATGGKGGNGGNGGRGG--LFGKGGNAGNGADGGTGGAGG-------
Mvan_1264|M.vanbaalenii_PYR-1       GEAGATGGKGGNGGNGGRGS--LFGRGGNAGNGGNGGTGGNGG-------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG-------
MAV_4827|M.avium_104                PTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAP------
                                                                                      

Mb3538|M.bovis_AF2122/97            GADNPTGIGGAGGTGGAGGTGGTGGAAGAGGAGGAVGTGGTGGVVGDVGN
Rv3514|M.tuberculosis_H37Rv         GADNPTGIG------GTGGDGGTGGAAGAGGAGGAAGTGGTGGMIGTTGN
MUL_4367|M.ulcerans_Agy99           -------------------SGGVGGVNGDGGAGGGGGRGGDGGS------
MMAR_5294|M.marinum_M               -------------------SGGVGGVNGDGGAGGGGGRGGDGGSSTTVAG
TH_3810|M.thermoresistible__bu      -------------------NVGFFSLFNLG--GAGGWGG--SGVDG----
MSMEG_0868|M.smegmatis_MC2_155      -------------------TGGQSTAAGPGKGGGGGGGG--GGAIL----
Mflv_5091|M.gilvum_PYR-GCK          -------------------AGGTGGTGGAGGTGGTGGTGGIGGAGS----
Mvan_1264|M.vanbaalenii_PYR-1       -------------------NGGTGGTGGNGGTGGTGGTGGIGGAGS----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------NAGLAGNAAVAGNAAVAGNAAVAG-------
MAV_4827|M.avium_104                -------------------PPAAPPLPEAPPIPAAPPVVPVPVVVP----
                                                                                      

Mb3538|M.bovis_AF2122/97            AGIGG---------------------------------------------
Rv3514|M.tuberculosis_H37Rv         AGVGG---------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               VGGAGGAGGAGGDSGMVAGAGGTGGQAGDGGFGGFGGAGIDGGGAAGARG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               GDGGAGGVGGAAEATGTGGAGGSGGAAGGGGSGASAVGAGLAGGAGGDGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               IGGAAGAGGSGFVAGADGNGGFGGAGGAGGAGDQGVSGAAPGEAGAVGFA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               GGAGGAGGAGGNGVGGGVNGAGGVGGAGGAGGGGGAGASGVGAGVAGGDG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               GAGGAGGAAGVGGAAGSGGVGGAAGVAGTGGDGGAGGSGGASDQGAAGVN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               PGEAGAVGFAGGAGGAGGVGGDSGAGGVNGSGGVGGAGGAGGGGGAGASG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               VGAGVAGGDGGTGGAGGAAGVGGAAGTGGVGGAAGVAGTGGDGGAGGSGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               ASDQGAAGVNPGEAGAVGFAGGAGGAGGAGGDSGAGGVNGSGGVGGAGGA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               GGGGGAGASGVGAGVAGGDGGTGGAGGAAGVGGAAGTGGVGGAAGVAGTG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               GDGGAGGSGGASDQGAAGVNPGEAGTVGFAGGAGGAGGVGGDSGAGGVNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               SGGVGGAGGAGGGGGAGASGVGAGVAGGDGGTGGAGGAAGVGGAAGSGGV
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               GGAAGVAGTGGDGGDGGAGGAGSDASVAGQAGFAGGSGGAGGVGGSAGAG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               GVNGSGGDGGAGGTGGIGGASATTAGVGGAGGAGGAGGTTGGGVGAAGLG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -------------------------TGGKGG----------------AGG
Rv3514|M.tuberculosis_H37Rv         -------------------------AGGQGGDGGAGGAGADADQPGATGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               GDGGHAGAGGAGGEGLSGGFNTGAAGGIGGAGGAGGTGGDSGGVGGVNGD
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            TGFAGGAGGAGGQGGSSGAGGTNGSGGAGGTGGQGGAGGAGGAGADNPTG
Rv3514|M.tuberculosis_H37Rv         TGFAGGAGGAGKAGGSSSAGGTNSSGSAGGTGRQSGTGGAGGAGADNPTG
MUL_4367|M.ulcerans_Agy99           ---------------STSTSGVGGAGGAGGNGGNAGFGVS-------AGG
MMAR_5294|M.marinum_M               GGAGGIGGRGGDGGSSTSTSGVGGAGGAGGNGGNAGFGVG-------AGG
TH_3810|M.thermoresistible__bu      ---------------VDVVGGNPDGGTPGAHGESHTPGV--------YTD
MSMEG_0868|M.smegmatis_MC2_155      ---------------IGANGGTVDGHAIGGNGGNGGNGS--------TTA
Mflv_5091|M.gilvum_PYR-GCK          ---------------TGGTGGTGGTGGTGGTGGTGGTGG--------TGG
Mvan_1264|M.vanbaalenii_PYR-1       ---------------TGGTGGTGGTGGTGGTGGTGGTGG--------TGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------NAAVGGVLNTGVSGAIGGSSHVGG---------AI
MAV_4827|M.avium_104                ---------------PVPVPVPVRIPVPDPVSPPQLLAP--------PRL
                                                                                      

Mb3538|M.bovis_AF2122/97            IGGAGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVGNAGIGGTGGTGGVG
Rv3514|M.tuberculosis_H37Rv         IGGTGGDGGTGGAAGAGGAGGAAGTGGTGGMIGTTGNAGVG---------
MUL_4367|M.ulcerans_Agy99           TGGSAGDGGAG---------------------------------------
MMAR_5294|M.marinum_M               TGGSAGDGGAGGFGGAGIDGSGAAGARGG---------------------
TH_3810|M.thermoresistible__bu      RQGEDGEDGTG---------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      AGGNGGTGGTGRVIAEGTGSTAEGTATGG---------------------
Mflv_5091|M.gilvum_PYR-GCK          TGGTGGKGGTG---------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGGKGGTG---------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      NESLGGSGSVG---------------------------------------
MAV_4827|M.avium_104                SVPQPVQPPVR---------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GAGGAGAAAAAGSSATGGAGFAGGAGGEGGAGGNSGVGGTNGSGGAGGAG
Rv3514|M.tuberculosis_H37Rv         -----------------------------GAGGSSGAGGTNGSGGAGGTD
MUL_4367|M.ulcerans_Agy99           -------------------------------------GGAGGVDGVGGAS
MMAR_5294|M.marinum_M               ------------------------------DGGAGGGGGAGGVDGVGGAS
TH_3810|M.thermoresistible__bu      -------------------------------------TGIGGRG------
MSMEG_0868|M.smegmatis_MC2_155      ------------------------------DGGHSTGTGIGGNGGIGSVY
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------GTGGAGGTGGDGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------GTGGDGGTGGTGGTGGTG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------------GSTAVGGGAH
MAV_4827|M.avium_104                ------------------------------------------------VP
                                                                                      

Mb3538|M.bovis_AF2122/97            GKGGTGGAGGSGADNPTGAGFAGGAGGTGGAAGAGGAG------------
Rv3514|M.tuberculosis_H37Rv         GQGGAGGAGGAGADNPTGIGGTGGDGGTGGAAGAGGAG------------
MUL_4367|M.ulcerans_Agy99           GNGGAAGAGGAGGSG-IGAGIDGGAGGAGGTG------------------
MMAR_5294|M.marinum_M               GNGGAAGAGGAGGSG-IGAGIDGGAGGDGGIG------------------
TH_3810|M.thermoresistible__bu      --GNGGSSSGTHPMAEDGEHVKALDGRPG---------------------
MSMEG_0868|M.smegmatis_MC2_155      AYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGD
Mflv_5091|M.gilvum_PYR-GCK          GTGGTGGTGGTGGTGGAGDGTGGTGGTGG---------------------
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGTGGTGGTGGAGDGLGGTGGTGG---------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      TGVGGGVSTGVGVGSHVGGGISESLGGSG---------------------
MAV_4827|M.avium_104                QPPSPPQVGGTVPQSPPQHQTPPGEGTPP---------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ---------------------------------------------GATGT
Rv3514|M.tuberculosis_H37Rv         ---------------------------------------------GAAGT
MUL_4367|M.ulcerans_Agy99           ------------------------------------------------GA
MMAR_5294|M.marinum_M               ------------------------------------------------GA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      NGGDALVMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGS
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GGTGGVVGATGSAGIGGAGGRGGDGGDGASGLG------LGLSGFDGGQG
Rv3514|M.tuberculosis_H37Rv         GGTGGMIGTTGNAGVGGAGGQGGDGGAGGAGADADQPGATGGTGFAGGAG
MUL_4367|M.ulcerans_Agy99           AGFPGGGGTTGAWGTGGAGGAGGAGGAGDHGGVGVNPGDSGTAGWAGGAG
MMAR_5294|M.marinum_M               AGFPGGGGTTGAWGTGGAGGAGGSGGAGDHGGVGVNPGDSGTAGWAGGAG
TH_3810|M.thermoresistible__bu      -------------LDGGNGSHGGN----------------------GGHG
MSMEG_0868|M.smegmatis_MC2_155      ITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNG
Mflv_5091|M.gilvum_PYR-GCK          --------------TGGQGGQGGQG-------------------GTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       --------------TGGFGGQGGQG-------------------GTGGTG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------SVGGSTAVGGG--------------------AHTGVG
MAV_4827|M.avium_104                -------------KPDGPGNYGGGHVP------------------TPGAG
                                                                                      

Mb3538|M.bovis_AF2122/97            GQGGDGGSAGAGGINGAGGAGGDGGDGGDGATGAAG-LGDNGGVG-----
Rv3514|M.tuberculosis_H37Rv         GAGGSGGSSCAGGTNGSGGAGGTCGQVVAGGAGISFSNGSNGGTG-----
MUL_4367|M.ulcerans_Agy99           GAGGAGGSAAFNGVNGAG--------------------------------
MMAR_5294|M.marinum_M               GAGGAGGSAAVNGVNGAG--------------------------------
TH_3810|M.thermoresistible__bu      GRGGFLGIG-----------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGT
Mflv_5091|M.gilvum_PYR-GCK          GQGGLGGGG-----------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GQGGLGGVG-----------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGVSTG--------------------------------------------
MAV_4827|M.avium_104                GSGGSGGGHVP---------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ----GDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDN
Rv3514|M.tuberculosis_H37Rv         ----GTGGVGGTGGDGGNAGTG-AGDPGKGGTGGTGGTGGSGGAGGSGGA
MUL_4367|M.ulcerans_Agy99           ----GAGGNGGAGGGGGAGASG-IGAGVAGGDGGTGGTGGAAGTGGAA--
MMAR_5294|M.marinum_M               ----GAGGNGGAGGGGGAGASG-IGAGVAGGDGGTGGTGGAAGTGGAA--
TH_3810|M.thermoresistible__bu      ----GSGGWGGHGGNGGD-------TDADGGNGGDGGNGGSAGRGGTG--
MSMEG_0868|M.smegmatis_MC2_155      FVNAGANGNGGAGGAGGV-------SEGEGGTGGHGGDGGRGGDGALG--
Mflv_5091|M.gilvum_PYR-GCK          ----GTGGQGGTGGTGGQGG-----TGGTGGTGGTGGTGGAGGDGGLG--
Mvan_1264|M.vanbaalenii_PYR-1       ----GTGGTGGTGGTGGQGG-----TGGTGGTGGTGGTGGAGGDGGLG--
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------VGVGSHVGGGISES-----LGGSGSVGGSTAVGGGAHTGVGG--
MAV_4827|M.avium_104                -----TPGAGGSGGSGGG-------HVPTPGTGGPGGTGGSGGGHVPTP-
                                                                                      

Mb3538|M.bovis_AF2122/97            NFNGGQGGAGGQGGQGGLG-------------------------------
Rv3514|M.tuberculosis_H37Rv         NFNGGTGGTGGTGGKGGLN-------------------------------
MUL_4367|M.ulcerans_Agy99           ----GTGGTGGAAGAAG---------------------------------
MMAR_5294|M.marinum_M               ----GTGGTGGAAGAAG---------------------------------
TH_3810|M.thermoresistible__bu      ----GLRGVFGINGGNG---------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ----GNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAG
Mflv_5091|M.gilvum_PYR-GCK          ----GLGGFGGSGGTGG---------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----GLGGFGGVGGTGG---------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----GVNTGVGVGSHVG---------------------------------
MAV_4827|M.avium_104                ----GAGTPGGSGG------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -----------GASTTSINANGGAGGNGGTGGKGGAGGAGTLGVGGSGGT
Rv3514|M.tuberculosis_H37Rv         -----------TDGLSSATS--GTGGTGGTGGKGGTGGAGDDSAGGTGGT
MUL_4367|M.ulcerans_Agy99           --------------------------SAGDGGAGGAGG------------
MMAR_5294|M.marinum_M               --------------------------TAGDGGAGGAGG------------
TH_3810|M.thermoresistible__bu      -----------------------------RAGLGGRGX------------
MSMEG_0868|M.smegmatis_MC2_155      RIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSN
Mflv_5091|M.gilvum_PYR-GCK          -----------------------------QGGLGGPGG------------
Mvan_1264|M.vanbaalenii_PYR-1       -----------------------------QGGQGGPGG------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------GGISESLGGSGS------------
MAV_4827|M.avium_104                ----------------------------GHLPFPGAGS------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GGDGGDAGAGGGGGFGG----------------------AAGKAGGGGNG
Rv3514|M.tuberculosis_H37Rv         GGAGGNAGAGGLANTGG----------------------TAGNAGIGGDG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GVGGDGGEGATGLGLD-LSGFAGGQGGQGGAGGNAGAGGING-AGGTGGT
Rv3514|M.tuberculosis_H37Rv         GQGGNGGQGDSGSGLGGQPGFAGGAGGKGGAGGSSGAGGTNG-SGGAGGA
MUL_4367|M.ulcerans_Agy99           -----AGDDGSAGVVSGDPGTAGKAGGAGG-AGGVGGNGVAGGVNGSGGA
MMAR_5294|M.marinum_M               -----AGDDGSAGVVSGDPGTAGKAGGAGG-AGGAGGNGVAGGANGSGGA
TH_3810|M.thermoresistible__bu      ---------------------XXXGGGVG--AAVRSGNGVFS---GGGGT
MSMEG_0868|M.smegmatis_MC2_155      SGINGGHGGNGGQGTIEANGPSAVASGIG--AGGNGGDGIDG---GLGGN
Mflv_5091|M.gilvum_PYR-GCK          --------------------STGGAGGAGGQAGTAGKGGLFG---GSGSA
Mvan_1264|M.vanbaalenii_PYR-1       --------------------STGGAGGAGGQAGVAGKGGLFG---GSGSA
MLBr_01183|M.leprae_Br4923          ---------------------MPLFLNAEPQALTAAANTLEG--LSAATV
MAB_4284c|M.abscessus_ATCC_199      ---------------------VGGSTAVGGGAHTSAINDALGGSGSVGGS
MAV_4827|M.avium_104                -----------------------TPGGSGGGHLPTPGAGTPG-----GGL
                                                                             .     .  

Mb3538|M.bovis_AF2122/97            GGAGGDG-APATLIGGPDGGDGGQGGIG---GDGGNAGFGAGVPGDGGIG
Rv3514|M.tuberculosis_H37Rv         GGQGGAGGAGISFSNGSNGGTGGTGGVGGTGGDGGNAGTGAGDPGKGGTG
MUL_4367|M.ulcerans_Agy99           GGAGGAGGTGGAGASGVPASVDGGDGGAGGAG------GAAGTGGSGGSA
MMAR_5294|M.marinum_M               GGAGGAGGTGGAGASGVPASVAGGDGGAGGAGGAAGSGGAAGTGGSGGSA
TH_3810|M.thermoresistible__bu      PSAGFGVPTTIQFPAGSCTSRAVSREG-----------------------
MSMEG_0868|M.smegmatis_MC2_155      GGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYG
Mflv_5091|M.gilvum_PYR-GCK          GKAGATGAAGASGGKGAQGATGAQGATG----------------------
Mvan_1264|M.vanbaalenii_PYR-1       GTAGVTGASGASGGKGAQGATGAQGATG----------------------
MLBr_01183|M.leprae_Br4923          ASNAAAAQLTTEIAPPAADDVSILLAHF----------------------
MAB_4284c|M.abscessus_ATCC_199      TAVGGGAHTSAINESMNSSINASHSSSMN---------------------
MAV_4827|M.avium_104                GGFGGGHAPAPGGGLGGGGGHAPAPGGG----------------------
                                       .                                              

Mb3538|M.bovis_AF2122/97            GTGGAGGAGGAGGAGDAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLA
Rv3514|M.tuberculosis_H37Rv         GTGGTGGSGGAGGSGGANFNG------GTGGTGGTGGTGGKGGMGGIAGD
MUL_4367|M.ulcerans_Agy99           GNTGAGGAGG---------------------------------AGGAGGS
MMAR_5294|M.marinum_M               GNTGAGGAGGDGGVGGA--------GGNAEGPGLFGYDGGMGGAGGAGGS
TH_3810|M.thermoresistible__bu      ------------------------------------------------IM
MSMEG_0868|M.smegmatis_MC2_155      STLGGNATGTATAGKGG--------EASNGGVAGNGGNALVMAAGTTGVA
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------------AQGA
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------------AQGA
MLBr_01183|M.leprae_Br4923          ----------------------------------------------FSGH
MAB_4284c|M.abscessus_ATCC_199      -----------------------------------------------ESF
MAV_4827|M.avium_104                -------------------------------------------------L
                                                                                      

Mb3538|M.bovis_AF2122/97            SAASGDGGNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAGAGG-------
Rv3514|M.tuberculosis_H37Rv         GGPGGDGGNAGVGGKGGTNGNGG--SGGTGGTGGAGGNAGAGG-------
MUL_4367|M.ulcerans_Agy99           AASTGVNGDGGAGGAGGVGGLGGD-SAATAGGGGAGGDG-----------
MMAR_5294|M.marinum_M               AGSTGVNGDGGAGGAGGVGGLGGD-SAATAGGGGAGGDGGAGGAAGAGAG
TH_3810|M.thermoresistible__bu      PSSRAASARAGAACASSTSRSRRS-FCCSRA-------------------
MSMEG_0868|M.smegmatis_MC2_155      TGNTATGGDGGAATTAGATGGAGG-FSNIAAIHGAITDS-----------
Mflv_5091|M.gilvum_PYR-GCK          TGATGAAGKAGATGAAGAAGAAGS-AGTTGAQGSAGTN------------
Mvan_1264|M.vanbaalenii_PYR-1       TGATGASGAQGSAGSAGSAGVAGS-AGTTGAQGSAGTN------------
MLBr_01183|M.leprae_Br4923          GRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETANHDSL----------
MAB_4284c|M.abscessus_ATCC_199      GSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH------------
MAV_4827|M.avium_104                GGFGGGHSGGGLGGLGGGHK------------------------------
                                           .  *                                       

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               IAGSAGDGGHAGAGGAGGAGLSGGFNTGAAGGIGGAGGAGGTGGDSGGVG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               GVNGDGGAGGIGGHGGDGGSSTSTPGVGGAGGAGGDGGSAGIGVGVAGNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               GDAGAGGAGGSGGAGIDGSAATGAHGGAGGSGGVGGQATNSAGVGGDGGA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               GGAGGNGGAGANGTASPGVPGPGAGGDAGAGGNGGAGGGSGARNGDGGDG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5294|M.marinum_M               GVGGRGGDGHIHPGGSRINGGDGGVGGAAGLAGVNGASAAGNAGHGGDGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ----------------------------LANTGGTAGNAGIGGAGGRGGD
Rv3514|M.tuberculosis_H37Rv         ----------------------------LANTGGTAGNAGIGGDGGQGGN
MUL_4367|M.ulcerans_Agy99           ------------------------------GKGGAGGAGVNGVGGGDGGK
MMAR_5294|M.marinum_M               AGGNGSVGAAGADGVGAGATGGFGSQGGDGGKGGAGGAGVNGVGGGDGGK
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ------------------------------------TAISGHGGAGNGGN
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------GANGAN
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------GANGAN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GGAGDSGALSQDGNGFAGGQGGQGGAGGNAGAGGING--AGGTGGTGGAG
Rv3514|M.tuberculosis_H37Rv         GGQGDSGSGLGGQPGFAGGPGGKGGAGGNAGTGGTNGSGAGGAGGQGGAG
MUL_4367|M.ulcerans_Agy99           GG---TGGAGGAGGAGSDGIIPSNGGLG----------------------
MMAR_5294|M.marinum_M               GGSGGTGGAGGAGGAGSDGILPSNGGLGGLGGSGGLGGAGGAGTDGGASG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGKGADGWVQAYDPAGPVGSKIAN--------------------------
Mflv_5091|M.gilvum_PYR-GCK          GSQGAAGKAGATGTTGATG-------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GSQGAAGKAGATGTTGATG-------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GDGAPAT-----LIGGPD--GGDGGQGGGAGFGSGVAGAAGAGGNGGKGG
Rv3514|M.tuberculosis_H37Rv         GAGISFSNGSNGGTGGTGGVGGTGGDGGNAGTGAGDPGKGGTGGTGGTGG
MUL_4367|M.ulcerans_Agy99           ----------------------------GNGGNGGNGGQAFGDGVGGAGG
MMAR_5294|M.marinum_M               ATGTYGNGGTGGAGGAGGNATGGAGEGGGLGGNGGTGGQAFGDGVGGAGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------SSAVAGNGGDGG
Mflv_5091|M.gilvum_PYR-GCK          -----------------------------------------AAGEDGDAG
Mvan_1264|M.vanbaalenii_PYR-1       -----------------------------------------AAGDAGDPG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            DGGTGGTGGTNFAGGQGGAGGRGGAGGNGANGVGDNAAGGDGGNGGAGGL
Rv3514|M.tuberculosis_H37Rv         SGGAGGSGGANFNGGTGGTGGTGGTGGKGGMGG----IAGDGGPGGDGGN
MUL_4367|M.ulcerans_Agy99           IGGKGGNAAIGTIVINGGVGGAGGSGGLGGATE--DGVGGVGCAGGAGGN
MMAR_5294|M.marinum_M               IGGKGGNAAIGTLVVNGGVGGAGGSGGLGGATE--NGVGGVGGAGGAGGN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      VNGTGG--------ASGGDGGNGGNTSVWKSGG--QTADGEHNTGGNGGN
Mflv_5091|M.gilvum_PYR-GCK          SGGSG---------INGGAGGAGG-------------AGGEGGEGGDGGK
Mvan_1264|M.vanbaalenii_PYR-1       SEAVD---------INGGAGGAGG-------------AGGEGGEGGAGGA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GGGGGTGGTNGNGGLGGGGGNGGAGGAGGTPTGSGTEGTGGDGGDAGAGG
Rv3514|M.tuberculosis_H37Rv         AGVGGKGGTNGNGGSGGTGGTGGPGGSGGAPTGSGTGGKGGAGGDGGDGA
MUL_4367|M.ulcerans_Agy99           GGRGDM-----LFTVGGSGGTGGDGGGGGSASGSGTGGSGGTGGVGGIGG
MMAR_5294|M.marinum_M               GGRGDT-----LFTAGGSGGTGGHGGGGGSASGSGTGGSGGTGGVGGIGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGDG---------SEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGG
Mflv_5091|M.gilvum_PYR-GCK          GGAG---------AEGGAGGGGGAGGSGAGGAG-------GAGGSGGSGG
Mvan_1264|M.vanbaalenii_PYR-1       GGDG---------SEGGAGGSGGAGGSGTGGAG-------GAGGSGGSGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            NGGSATGVGNGGNGGDGGNGGDGGN--GAPGGFGGGAGAGGLGGSGAGGG
Rv3514|M.tuberculosis_H37Rv         DGGAATGVGDGGDGGNGGNGGNGGTGVGSPGGLGGAGGTGGLGGAGAGGG
MUL_4367|M.ulcerans_Agy99           DGK------LGGFGGDGGDGGDGGFGVIGGQGGGGGFGGLGGTGAGGAPS
MMAR_5294|M.marinum_M               DGK------VGGSGGDGGDGGDGGSGVIGGQGGGGGIGGFGGTGAGGAPS
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      NGG------ADGTPGTAGTTGANNP-------------------------
Mflv_5091|M.gilvum_PYR-GCK          SGG------SGGSGGAAGDSDD----------------------------
Mvan_1264|M.vanbaalenii_PYR-1       SGG------AGGSGGAAGDSD-----------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            TDGDDGNGGSPGTDGS
Rv3514|M.tuberculosis_H37Rv         ADGDDGDDGQPGNNGS
MUL_4367|M.ulcerans_Agy99           DKGINGEPGNPG----
MMAR_5294|M.marinum_M               DNGTNGEPGNPG----
TH_3810|M.thermoresistible__bu      ----------------
MSMEG_0868|M.smegmatis_MC2_155      ----------------
Mflv_5091|M.gilvum_PYR-GCK          ----------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------
MLBr_01183|M.leprae_Br4923          ----------------
MAB_4284c|M.abscessus_ATCC_199      ----------------
MAV_4827|M.avium_104                ----------------