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LQDSRQRKKQDQRSPTHLTREHPMKTRTVKPAKVFAGCAIALGAALAGCGTNNDGGPTSTSTTTTTTTTT TTTITPAPSGAPEGTPAPGPTGGGGPDGGSGAIPGGPTGGGGPEGGSGSIPGGPTGGGGPEGGGGHIPGV GGGHGGPGGGGGCVDNVGCVSIP
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_3220 | - | - | 100% (163) | hypothetical protein MAB_3220 |
M. abscessus ATCC 19977 | MAB_2532 | - | 1e-34 | 56.80% (125) | hypothetical protein MAB_2532 |
M. abscessus ATCC 19977 | MAB_3131c | - | 2e-11 | 43.00% (100) | translation initiation factor IF-2 (InfB) |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3541 | PE_PGRS55 | 1e-14 | 42.24% (116) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_4416 | - | 1e-33 | 53.62% (138) | hypothetical protein Mflv_4416 |
M. tuberculosis H37Rv | Rv3512 | PE_PGRS56 | 1e-14 | 42.24% (116) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 4e-10 | 41.24% (97) | translation initiation factor IF-2 |
M. marinum M | MMAR_2823 | - | 3e-42 | 59.57% (141) | PE-PGRS family protein |
M. avium 104 | MAV_2780 | - | 4e-45 | 65.38% (130) | hypothetical protein MAV_2780 |
M. smegmatis MC2 155 | MSMEG_5543 | - | 2e-26 | 58.43% (89) | hypothetical protein MSMEG_5543 |
M. thermoresistible (build 8) | TH_3810 | - | 7e-08 | 39.24% (79) | PUTATIVE - |
M. ulcerans Agy99 | MUL_3062 | - | 1e-12 | 51.56% (64) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_2314 | infB | 4e-15 | 52.87% (87) | translation initiation factor IF-2 |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 MSFVLISPEVVSAAAGDLANVGSTISAANKAAAAATTQVLAAGADEVSAR Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 IAALFGMYGLEYQAISAQVAAYHQQFVQTLRTGAASYMLAEATNVEQNLL Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 NLINAPTQTLLGRPLIGDGANATTPGGAGGDGGLLFGSGGNGAPGAPGQA Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGAGGSAGLLGNGGSGGAGGTGAPGGNGGNAGWLYGRGGVGGAGGIGGGT Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGAGGHAWLFGHGGTGGIGGGPGGNGGWLLGNGGHGGAGGIGGGSGGAGG Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 NGGWLLGNGGIGGAGGTGGGAGGTGGNAAWLLGGGGTGGAGGIGGGNGGH Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGNGGWLLGNGGNGGLGGDGDGGTGGGHGGNGGNPGWLLGTAGGGGNGGA Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GSTGTAGGGSGGTGGDGGTGGRGGLLMGAGAGGHGGTGGAGGAGVDGGGA Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGAGGAGGNGGAGGQAALLFGRGGTGGAGGYGGDGGGGGDGFDGTMAGLG Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GTGGSGGTGGDGGAPGNGGAGGAGQLLSHSGVAGASGKGGAGGTGGNGGA Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GSAGADAPAGSGAMGSTGFAGGAGGDGGNGGGSGASQGNGGNGGNGGTGG Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 KGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGNAGAGGTGFTQGADGNAGN Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGAGGTGGTGGAAGTGTGG Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 QQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGNAGA Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGAG Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQD Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGQGGTGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTA Rv3512|M.tuberculosis_H37Rv --------------------PQGADGNAGNGGDGGVGGNGGNGADNTTTA MUL_3062|M.ulcerans_Agy99 -----------------MAFVLAVPDMVAEAAADLAG--VGSVIDAANTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 AAG-TTGGAGGAGGAGGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGT Rv3512|M.tuberculosis_H37Rv AAG-TTGGAGGAGGAGGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGT MUL_3062|M.ulcerans_Agy99 AAGSTTGIVAAAEDEVSAAIAALFSGHGQAYQQISTR------------V TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -----------------------------------------------MQD Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ------------------------------------------------MA Mvan_2314|M.vanbaalenii_PYR-1 ------------------------------------------------MA MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGDGALAGSSGGAGGKGGNGGDAGKAGTGSAPGTAGTGGDGGKGGNGGIG Rv3512|M.tuberculosis_H37Rv GGDGALAGSSGGAGGKGGNGGDAGKAGTGSAPGTAGTGGDGGKGGNGGIG MUL_3062|M.ulcerans_Agy99 AEFHAQFERVFAAGVQAYSGAEAANASFLQDPLQTALN-----ATNKPVQ TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M --------------------MRSQARTTFAVFGGGAMLVLA-----VACG MAV_2780|M.avium_104 ------------------------------MFGGAAMLVLA-----VGCG MAB_3220|M.abscessus_ATCC_1997 SRQRKKQDQRSPTHLTREHPMKTRTVKPAKVFAGCAIALGAAL---AGCG Mflv_4416|M.gilvum_PYR-GCK --------------------MNSPLRKALIAAGGTTVLMLA-----VGCG MLBr_01556|M.leprae_Br4923 GKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRESFG Mvan_2314|M.vanbaalenii_PYR-1 GKARVHELAKELGVTSKEVLARLSEQGEFVKSASSTVEAPVARRLRESYG MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 AAGTTGPVGTGASGGTGGSGGAGGTGGDGGAANGGTAGAGGAGGNGGKGG Rv3512|M.tuberculosis_H37Rv AAGTTGPVGTGASGGTGGSGGAGGTGGDGGAANGGTAGAGGAGGNGGKGG MUL_3062|M.ulcerans_Agy99 DLTGRPLVGNGANG-------VPGTGANG-AAGGWLLGNGGAGGSGAAG- TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M GGE----------------------------------------------- MAV_2780|M.avium_104 GGH----------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 TNN----------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK GSD----------------------------------------------- MLBr_01556|M.leprae_Br4923 GIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAPVQ Mvan_2314|M.vanbaalenii_PYR-1 GSKSDKTKAAPSGNGAAGATVKPSAPQSRPGPKPGPPVAQQPAAPAAPPA MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 DGGAGVTSSTAGNSGGAGGSGGKGGDAGAGGAGATPGANGIAGNGGDGGD Rv3512|M.tuberculosis_H37Rv DGGAGVTSSTAGNSGGAGGSGGKGGDAGAGGAGATPGANGIAGNGGDGGD MUL_3062|M.ulcerans_Agy99 ---------QAGGDGGAAGLIGAGGAGGAG--GNSPLRN--TANGGNGGT TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 VDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPH Mvan_2314|M.vanbaalenii_PYR-1 APP---APPTPAAAPPSPAP----AAPAAATPAEPAAPS-ARPGPTPGPR MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GAAGAVGISGATGAGDGGHGGTGGAGGNGGTGGAGGSGIDGVGGGTGGTG Rv3512|M.tuberculosis_H37Rv GAAGAVGISGATGAGDGGHGGTGAAGGNGGTGGAGGSGIDGVGGGTGGTG MUL_3062|M.ulcerans_Agy99 GGAG------------------GLLFGPGGVGGAGGASFL-----TGGTG TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------NKGPSSTTPTTTPTTTVPSS----- MAV_2780|M.avium_104 -------------------------KGGPS-TTSTTTPTTTPSTSV---- MAB_3220|M.abscessus_ATCC_1997 -------------------------DGGPTSTSTTTTTTTTTTTTI---- Mflv_4416|M.gilvum_PYR-GCK -------------------------GREETTTSTTTESSVTTTTTT---- MLBr_01556|M.leprae_Br4923 PGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAP---- Mvan_2314|M.vanbaalenii_PYR-1 PG----PSAPKPG-APKPAARTPRVGNNPFSSQQPVERPAPRPQGPGGPR MSMEG_5543|M.smegmatis_MC2_155 ------------------------MAMAEPAPPPCVNADGTPCSDIG--- Mb3541|M.bovis_AF2122/97 GNGGNGAIGGAGGDAGGSGNSGGNGGTGGKGGNAGAGGAAGSNGGTVGAN Rv3512|M.tuberculosis_H37Rv GNGGNGAIGGAGGDAGGSGNSGGNGGIGGKGGNAGAGGAAGSNGGTVGAN MUL_3062|M.ulcerans_Agy99 GDGGAGGLFGAGG-------LGGVGGSGNVGGNGGAGGAGGLLAGLVGAG TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M ---------------PSSSPATESSPAPGGPSGTGGPE-GGGGGVPGGP- MAV_2780|M.avium_104 --------------VPSTTPGG-GGTVPGGPTGGGGPG-GGGGSIPGGP- MAB_3220|M.abscessus_ATCC_1997 --------------TPAPSGAPEGTPAPG-PTGGGGPD-GGSGAIPGGP- Mflv_4416|M.gilvum_PYR-GCK --------------APSTPETTMAPETTGAPAPGDPSQPGGGGSIPGGP- MLBr_01556|M.leprae_Br4923 --------------RPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGG- Mvan_2314|M.vanbaalenii_PYR-1 PGPGAGGPRPGGGPRPGASPGSMPPRPQGARPGGGPRP--GGGPRPGGGP MSMEG_5543|M.smegmatis_MC2_155 ----------------TAGPGGATGQIPGGPGGTAGPG-GASGAIPGGP- Mb3541|M.bovis_AF2122/97 GTGGDGGNGGAAGAATAGSNGGAGTGSAGGNGGTGGRGGSGGAGGDGIGG Rv3512|M.tuberculosis_H37Rv GTGGDGGNGGAAGAATAGSNGGAGTGSAGGNGGTGGRGGSGGAGGDGIGG MUL_3062|M.ulcerans_Agy99 --GGDGGSG--------------GLGAAGGDGGNGGRAGLFGGAG-GAGG TH_3810|M.thermoresistible__bu ---------------------------VDGDGGSGGRTGLFSKLS----- . . MMAR_2823|M.marinum_M -------TGSGGPGGGGGSIPG-------GPTGGGGPGGGGGTIPGVGGG MAV_2780|M.avium_104 -------TGGGGPGGGGGSIPG-------GPTGGGGPGGGGGSIPGVGGG MAB_3220|M.abscessus_ATCC_1997 -------TGGGGPEGGSGSIPG-------GPTGGGGPEGGGGHIPGVGGG Mflv_4416|M.gilvum_PYR-GCK -------TGSGGPEGGGGSIPG-------GPTGSGGPDGGGGSIPGGPTI MLBr_01556|M.leprae_Br4923 RP---GAPVGGRSDAGGGNYRG-------GGVG-ALPGGGSGGFRGRPGG Mvan_2314|M.vanbaalenii_PYR-1 RPTPGGAGRPGGGGGGGGNYRG-------GGAGGGAPAAGGGGFRGRPGG MSMEG_5543|M.smegmatis_MC2_155 -------GGAAGPDGATGSIPG-------GPAGTAGPDGATGVIPGGPGG Mb3541|M.bovis_AF2122/97 VGGGKGGNGADGEVGGAGGAGGSGPNTSPGGNGGQGGQGGSGGAGGAAGA Rv3512|M.tuberculosis_H37Rv VGGGKGGNGADGEVGGAGGAGGSGPNTSPGGNGGQGGQGGSGGAGGAAGA MUL_3062|M.ulcerans_Agy99 MGATGGHSGGD---GGAGGDAG-----LLFGTGGAGGAGG-HAFDGDGGA TH_3810|M.thermoresistible__bu ----RGGDGGD---GGLG------------GNGGHGGGTGIISLLSLAGN .. * * . . MMAR_2823|M.marinum_M GGGPGGGGGCIGNI-CGSYP------------------------------ MAV_2780|M.avium_104 GGGPGGGGGCVGNV-CGAYP------------------------------ MAB_3220|M.abscessus_ATCC_1997 HGGPGGGGGCVDNVGCVSIP------------------------------ Mflv_4416|M.gilvum_PYR-GCK TGGPGGGSGSIPGGPTINIPVP---------------------------- MLBr_01556|M.leprae_Br4923 GGHGGGGRPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVGG Mvan_2314|M.vanbaalenii_PYR-1 G--GGGGRPGQRGGAAGAFGRPGGAPKRGRKSKRAKRAEYENMQAPVVGG MSMEG_5543|M.smegmatis_MC2_155 TAGPGGASGCIPNVGCATIPAP---------------------------- Mb3541|M.bovis_AF2122/97 GGAGGGANGTAGNGGQGGAGGTGGAGAASSATNGGSGGAGGTGGAGGTGG Rv3512|M.tuberculosis_H37Rv GGAGGGANGTAGNGGQGGAGGTGGAGAASSATNGGSGGAGGTGGDGGSGG MUL_3062|M.ulcerans_Agy99 GGAGGNAGLMFSSGGSGGVGGAG-------SIDGGAGGAGGDAGWLGGGG TH_3810|M.thermoresistible__bu GGNGGNGYRTTDNN----------------ALDGGHGGNGGNVGFFSLFN *.. . MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 VRLP------------------------------------HGNGETIRLA Mvan_2314|M.vanbaalenii_PYR-1 VRLP------------------------------------HGNGETIRLA MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 AGGDGVGGAGGGNGGHGGDAGDGGNGANGNNRSSGSFLAAGGTGGAAGDG Rv3512|M.tuberculosis_H37Rv AGG--TGG-------------------------------AGGTGGAAGDG MUL_3062|M.ulcerans_Agy99 AGG------------------------------------AGGFG-TISDG TH_3810|M.thermoresistible__bu LGG---------------------------------------------AG MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 RGASLSDFAEKIDANPAALVQALFNLGEMVTATQSVGDETLELLGSEMNY Mvan_2314|M.vanbaalenii_PYR-1 RGASLSDFAEKINANPASLVQALFNLGEMVTATQSVGDETLELLGGEMNY MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GQGGQGGAGGGAGGQGGAGGAGGTGGNGGNITGGTAGTAGAAGNGGAAGK Rv3512|M.tuberculosis_H37Rv GQGGQGGAGGGAGGQGGAGGAGGTGGNGGNITGGTAGTAGAAGNGGAAGK MUL_3062|M.ulcerans_Agy99 GAGGRGGGGGQLLGNGGAGGAGGQGGNDG-------GAGGLGGNGVLIGN TH_3810|M.thermoresistible__bu GWGGSGVDGVDVVGGNPDGGTPG-------------AHGESHTPGVYTDR MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 NVQVVSPEDEDRELLEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHGKT Mvan_2314|M.vanbaalenii_PYR-1 VVQVVSPEDEDRELLESFDLTYGEDEGGEEDLEIRPPVVTVMGHVDHGKT MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGAGGQGGTGGGTGGQGGAGGDGGAGGTGGDRTVGGGTVPAGSGGQGGNA Rv3512|M.tuberculosis_H37Rv GGAGGQGGTGGGTGGQGGAGGDGGAGGTGGDRTVGGGTVPAGSGGQGGNA MUL_3062|M.ulcerans_Agy99 GGNGGVGGVGETPGGDGGGGISGLLLGADG------FNAPAGSSPVHALQ TH_3810|M.thermoresistible__bu QGEDGEDGTGTGIGGRGGNGGS-----SSG-------THPMAEDGEHVKA MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 RLLDTIRKANVREAEAGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAF Mvan_2314|M.vanbaalenii_PYR-1 RLLDTIRNATVREGEAGGITQHIGAYQVTVDLDGTERPITFIDTPGHEAF MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGGGAGGQGGADGGSGGDGGDAGTGGNGGNGGNRNSGNGTGGAGGNGGGG Rv3512|M.tuberculosis_H37Rv GGGGAGGQGGADGGSGGDGGDAGTGGNGGNGGNRNSGNGTGGAGGNGGGG MUL_3062|M.ulcerans_Agy99 QQALAAINAPVQELTG----------------RPLIGNGLPGSAG----- TH_3810|M.thermoresistible__bu LDGRPGLDG----------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 TAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKID Mvan_2314|M.vanbaalenii_PYR-1 TAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKID MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ANGGAGGAGGSGGGTGGNGGAGGDAGDAGNGGNGNGTGNGGNGGNGGIAG Rv3512|M.tuberculosis_H37Rv ANGGAGGAGGSGGGTGGNGGAGGDAGDAGNGGNGNGTGNGGNGGNGGIAG MUL_3062|M.ulcerans_Agy99 ----SGAAGAPGGWLLGDGGAGGSAAATPG-------AAGGAGGAAGLVG TH_3810|M.thermoresistible__bu ----------------GNGSHGG---------------NGGHGGRGGFLG MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 KEGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLLT Mvan_2314|M.vanbaalenii_PYR-1 KEGADPAKIRGQLTEYGLVPEEYGGDAMFVDISAKQGTNIEALLEAVILT MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 MGGNGGAGTGSGNGGNGGSGGNGGNAGMGGNSGTGSGDGGAGGNGGAAGT Rv3512|M.tuberculosis_H37Rv MGGNGGAGTGSGNGGNGGSGGNGGNAGMGGNSGTGSGDGGAGGNGGAAGT MUL_3062|M.ulcerans_Agy99 AGGAGGAGANTGIS-NPGFGGAGGAGGAG--AGAGGGVGEAGGAGGLLGA TH_3810|M.thermoresistible__bu IGGSGGWG---------GHGGNGGD------TDADGGNGGDGGNGGSAGR MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ADAALDLRANSGMEAQGVAIEAHLDRGRGPVAT--VLVQRGTLRIGDSVV Mvan_2314|M.vanbaalenii_PYR-1 ADASLDLRANPDMEAQGVAIEAHLDRGRGPVAT--VLIQRGTLRVGDSVV MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGTGGDGGLTGTGGTGGSGGTGGDGGNGGNGGNGADNTANMTAQAGGDGG Rv3512|M.tuberculosis_H37Rv GGTGGDGGLTGTGGTGGSGGTGGDGGNGGNG---ADNTANMTAQAGGDGG MUL_3062|M.ulcerans_Agy99 GGTGGGGGVAPSLVDGGTGGAGGAGGAGGLFG----------GIFGAGGG TH_3810|M.thermoresistible__bu GGTGG-----------------------------------LRGVFGINGG MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 AGDAYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDR Mvan_2314|M.vanbaalenii_PYR-1 AGDAYGRVRRMVDEHGEDVEEALPSRPVQVIGFTSVPGAGDNFLVVDEDR MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 NGGDGGFGGGAGAGGGGLTAGANGTGGQGGAGGDGGNGAIGGHGPLTDDP Rv3512|M.tuberculosis_H37Rv NGGDGGFGGGAGAGGGGLTAGANGTGGQGGAGGDGGNGAIGGHGPLTDDP MUL_3062|M.ulcerans_Agy99 DGGAGGFTG-----------GIDGAGGVGGAGGN---------------- TH_3810|M.thermoresistible__bu NGRAG--------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 IARQIADRRSARKRNALAARSRKRISLEDLDSALKETSQLNLILKGDNAG Mvan_2314|M.vanbaalenii_PYR-1 IARQIADRRSARKRNALAARTRKRISLEDLDSALKETSQLNLILKGDNSG MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGNGGTGGNGGTGGTGGAGIGSLGGGTGGDGGNGGTGGNGGTGGEGGEVG Rv3512|M.tuberculosis_H37Rv GGNGGTGGNGGTGGTGGAGIGSLGGGTGGDGGNG---GNGGTGGEGGEVG MUL_3062|M.ulcerans_Agy99 --TGLLGGPGGSGGSGGDGIAKLGFNVDG--------GAGGAGVNGGFLF TH_3810|M.thermoresistible__bu -------------------------------------------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 TVEALEEALMGIQVDDEVALRVIDRGVGGITETNVNLASASDAIIIGFNV Mvan_2314|M.vanbaalenii_PYR-1 TVEALEEALLGIQVDDEVELRVIDRGVGGVTETNVNLASASDAIIIGFNV MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GAGGTGGAAGNGGDGGTGGTGGGDGGAGGTGGTGGTGGLGDPRVGGSGGD Rv3512|M.tuberculosis_H37Rv GAGGTGGAAGNGGDGGTGGTGGGDGGAGGTGGTGGTGGLGDPRVGGSGGD MUL_3062|M.ulcerans_Agy99 GSGGTG---GFGGVGGVG-TSTGIGGAGGRGGNAG-LLFSDAGVGGFGGF TH_3810|M.thermoresistible__bu --------------------------LGGRGXXXX--------------- MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 RAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRA Mvan_2314|M.vanbaalenii_PYR-1 RAEGKATELANREGVEIRYYSIIYQAIDEIESALKGMLKPVYEEKELGRA MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGTGGSGGAAGNGGNGGNAGAGGNGNGGTGGAGGIGGTGGNGGDAEPGVP Rv3512|M.tuberculosis_H37Rv GGTGGSGGAAGNGGNGGNAGAGGNGNGGTGGAGGIGGTGGNGGDAEPGVP MUL_3062|M.ulcerans_Agy99 GGTGGNAGWLGSGGSGG-AGGGSNGDGGAGGTGGSGGQ--IVGDGGAGGA TH_3810|M.thermoresistible__bu ---GGGVGAAVRSGNGVFSGGGGTPSAGFGVPTTIQFP---AGSCTSRAV MMAR_2823|M.marinum_M -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01556|M.leprae_Br4923 EIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRR Mvan_2314|M.vanbaalenii_PYR-1 EIRAIFRSSKVGNIAGCLVQSGIMRRNAKARLLRDNVVVAENLTISSLKR MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 PGAGGAGGAGTTGGKGGTGGNGSGTGSGGTGGDGGTGGGGGNGGTGWNGG Rv3512|M.tuberculosis_H37Rv PGAGGAGGAGTTGGKGGTGGNGSGTGSGGTGGDGGTGGGGGNGGTGWNGG MUL_3062|M.ulcerans_Agy99 GGQGDLLAAGGSGGDGGQGGDAVLIGTGGNGGNGASGVLAGIGGD--GGS TH_3810|M.thermoresistible__bu SREGIMPSSRAASARAGAACASSTSRSRRSFCCSRA-------------- MMAR_2823|M.marinum_M ---------------------------------------- MAV_2780|M.avium_104 ---------------------------------------- MAB_3220|M.abscessus_ATCC_1997 ---------------------------------------- Mflv_4416|M.gilvum_PYR-GCK ---------------------------------------- MLBr_01556|M.leprae_Br4923 EKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA Mvan_2314|M.vanbaalenii_PYR-1 EKDDVTEVRDGYECGLTLTYSDIKEGDVIETYELVEKART MSMEG_5543|M.smegmatis_MC2_155 ---------------------------------------- Mb3541|M.bovis_AF2122/97 KGDTGSGGGAGDGGKAPAGGTGGAGGDGGAGGKGGSGGV- Rv3512|M.tuberculosis_H37Rv KGDTGSGGGAGDGGKAPAGGTGGAGGDGGAGGKGGSGGV- MUL_3062|M.ulcerans_Agy99 RGLLLGEDGVNGEAAPPMTHIVLLGGDFPAAAS------- TH_3810|M.thermoresistible__bu ----------------------------------------