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RYKTSVLGTFGPMLFAGAAATAIATAPLTFAQPAPPPCFNADGTPCTALGTAGPGGAAGAIPGGPAGEAG PGGASGAIPGGPAGEAGPGGASGAIPGGPAGEAGPGGVSGSTNPGGVSGAAGPDGVSGCIPNVGCATIPV G*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1054 | - | - | 100% (142) | hypothetical protein Mflv_1054 |
| M. gilvum PYR-GCK | Mflv_4416 | - | 5e-19 | 47.83% (92) | hypothetical protein Mflv_4416 |
| M. gilvum PYR-GCK | Mflv_3843 | - | 4e-12 | 38.26% (115) | hypothetical protein Mflv_3843 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1485c | PE_PGRS27 | 3e-14 | 49.38% (81) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 1e-14 | 45.16% (93) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01556 | infB | 5e-10 | 34.75% (141) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_3220 | - | 6e-22 | 43.09% (123) | hypothetical protein MAB_3220 |
| M. marinum M | MMAR_2823 | - | 2e-22 | 41.09% (129) | PE-PGRS family protein |
| M. avium 104 | MAV_2780 | - | 8e-25 | 43.28% (134) | hypothetical protein MAV_2780 |
| M. smegmatis MC2 155 | MSMEG_5543 | - | 5e-48 | 74.11% (112) | hypothetical protein MSMEG_5543 |
| M. thermoresistible (build 8) | TH_3810 | - | 6e-07 | 37.93% (87) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4367 | - | 2e-13 | 49.48% (97) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-12 | 45.68% (81) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAGADEVSAR
MUL_4367|M.ulcerans_Agy99 MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGVLPAAGDEVSAA
Mb1485c|M.bovis_AF2122/97 MSLVIVAPETVAAAALDVARIGSSIGVANSAAAGSTTSVLAAGADEVSAA
Mvan_1264|M.vanbaalenii_PYR-1 --MMFLAP------------------PGGPGPISAAIQLTSTGSEATEPW
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 ----MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARR
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv IAALFGGFGLEYQAISAQVAAYHQR--FVQALSTGAGAYASAEAA-----
MUL_4367|M.ulcerans_Agy99 IAELFGGFGREYQAMGARVALLHDD--FVRALTAGGSAYGQAEALNMWPL
Mb1485c|M.bovis_AF2122/97 IATLFGSHAREYQAISTQVAAFHDR--FAQTLSAAVGSYVSAEATNAAPL
Mvan_1264|M.vanbaalenii_PYR-1 YVVSFGGSG----------APTPNN--LAASLVDLSGTSCG---------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 LRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGAT
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv -AAEQIVLGVINAPTQALLGRPLIGDGAN-ATTPGGAGGAGGLLFGNGGA
MUL_4367|M.ulcerans_Agy99 QELEQQALGVVNAPSMALFGRPSIGNGVDGVAGTGQAGGAGGILWGNGGN
Mb1485c|M.bovis_AF2122/97 ATLEHNVLNALNAPTQALLGRPLIGDGAAGAPGTGQAGGAGGILWGNGGA
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------LICNGQD---GTGQNG---GILFGNGGS
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 TAAPVQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQG
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GA-AGAPGQAGGPGGPAG--LWGNGGPGGAGGSGGGTGGAGGAGGWLF--
MUL_4367|M.ulcerans_Agy99 GG-LGAAGANGGAGGSAG--LIGTGGVGGAGG------------------
Mb1485c|M.bovis_AF2122/97 GG-SGAPGQVGGAGGAAG--LFGTGGAGGAGGAGAAGGAGGSGGWLLGNG
Mvan_1264|M.vanbaalenii_PYR-1 GWNSEIAGVSGGNGGNAG--LFGGNGGNGGNG------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 TPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPP
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GVGGAGGVGGAGGGTGGAGGPGGLIWGGGGAGGVGGAGGGTGGAGGRAEL
MUL_4367|M.ulcerans_Agy99 -VGAAG----MTGGSGGAGGGGGWLWGAGGSGGAAGAGG-----------
Mb1485c|M.bovis_AF2122/97 GVGGAGGQSLLGGATGGAGGNAG-LFGVGGTGGPGGPGG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ----------LGSGDGGNGGDAG-LFSLFGRGGNGGNGG-----------
TH_3810|M.thermoresistible__bu -----------VDGDGGSGGRTG-LFSKLSRGGDGGDGG-----------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 APRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPG----------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv LFGAGGAGGAGTDGGPGATGGTGGHGGVGGDGGWLAPGGAGGAGGQGGAG
MUL_4367|M.ulcerans_Agy99 ---------------------------SGGSGGWLWG-------------
Mb1485c|M.bovis_AF2122/97 ---------PGGPGGPGGPGGVGGTGGAGGLGGTLYGAGGHGG-------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GAGSDGGALGGTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQGGTG
MUL_4367|M.ulcerans_Agy99 -------------NAGQTAGAG-----------------VGGAGGAGGAG
Mb1485c|M.bovis_AF2122/97 -----AGGPGPIGGVGGHGGVGGAAG-------------LLGVGGHGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------------VGIAGATG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 ----------------------------------------APVGGRSDAG
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GAGGDGVLGGVGGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGAVGVGG
MUL_4367|M.ulcerans_Agy99 DAGDQGVSG-----------------------------------------
Mb1485c|M.bovis_AF2122/97 GHGAAGIAG-----------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 AVGAPGVAG-----------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 GGNYRGGGVG----------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv TGGQGGAGGAGAAGADAPASTGLTGGTGFAGGAGGVGGQGGNA-IAGGIN
MUL_4367|M.ulcerans_Agy99 ------------------VAPGEAGAVGFAGGAGGAGGAGGNG-VGGGVN
Mb1485c|M.bovis_AF2122/97 -----------------AAGKGGIFPDGSNGGAGGDAGDGGTGGRGGWLA
Mvan_1264|M.vanbaalenii_PYR-1 -------------------------ATGATGVTSNVTGGNGADAVGYGAT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 -----------------ALPGGGSGGFRGRPGGGGHGGGGRPGQRGGAAG
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GSGGAGGTGGQGGAGGMGGSGADNASGIGADGGAGGTGGNAGAGGAGGAA
MUL_4367|M.ulcerans_Agy99 GAGGAGGAGGVGGGGGAGASGVG----AGVAGGDGGTGGAGGAAGVGGAA
Mb1485c|M.bovis_AF2122/97 GAGGAGGDGGIGGTGGAGGAGFSR--ALIVAGDNGGDGGNGGMGGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 GAAGAAGAAGAAGKAGAVG--------------SAGTAGSAGAPGVWGNA
TH_3810|M.thermoresistible__bu ----LGGNGGHGGGTGIIS-------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 AFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGA
Mflv_1054|M.gilvum_PYR-GCK ------------------MRYKTSVLGTFG--------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GTGGTGGVVGAAGKAGIGGTGGQGGAGGAGSAGTDATATGATGGTGFSGG
MUL_4367|M.ulcerans_Agy99 GTGGTG------GAAGVAGTGGDGGDGGAGGAGSDASLAGQAG---FAGG
Mb1485c|M.bovis_AF2122/97 GPGGAG---GLISLLGGQGAGGDGGDGGAGGVGGDR-GAGANGNQAVNAG
Mvan_1264|M.vanbaalenii_PYR-1 G-----------------LPGAAGAAGGAGAIGTAG-VAGAAG----TAG
TH_3810|M.thermoresistible__bu ----------------LLSLAGNGGNGGNGYRTTDN-----------NAL
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 ----------------MQDSRQRKKQDQRSPTHLTR--------------
MLBr_01556|M.leprae_Br4923 SLSDFAEKIDANPAALVQALFNLGEMVTATQSVGDETLELLGSEMNYNVQ
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv AGGAGGAGGNTGVGGTNGSGGQGGTGGAGGAGGAGGVGADNPTGIGGTGG
MUL_4367|M.ulcerans_Agy99 SGGAGGVGGSAGAGGVNGSGGDGGAGAAGGAGGASAT-------VAGSGG
Mb1485c|M.bovis_AF2122/97 AGGAGGHGGDPGAGGAGGTGGAGSTIGAHGAAGASPT-------SGGNGG
Mvan_1264|M.vanbaalenii_PYR-1 ATGGTGVGGNGGAGQAGGIGGTGAAGAAGQAGTAGET--------GVTGG
TH_3810|M.thermoresistible__bu DGGHGGNGGNVGFFSLFNLGGAG--------------------------G
MMAR_2823|M.marinum_M -------MRSQARTTFAVFGG-----------------------------
MAV_2780|M.avium_104 -----------------MFGG-----------------------------
MAB_3220|M.abscessus_ATCC_1997 ----EHPMKTRTVKPAKVFAG-----------------------------
MLBr_01556|M.leprae_Br4923 VVSPEDEDRELLEPFDLTYGEDQGDEDELQVRPPVVTVMG-----HVDHG
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv TGGKGGAGGAGGQGGSSGAGGTNGSGGAGGTGGQGGAGGAGGAGADNPTG
MUL_4367|M.ulcerans_Agy99 VGGDGGAGGAAG--------------------------------------
Mb1485c|M.bovis_AF2122/97 AGGNGAHFSSGGKAG-----------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 VGGIGGQGTEGG--------------------------------------
TH_3810|M.thermoresistible__bu WGGSG---------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 KTRLLDTIRKAN--------------------------------------
Mflv_1054|M.gilvum_PYR-GCK ---------------------------------PMLFAGAAATAIATAPL
MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------------M
Rv3508|M.tuberculosis_H37Rv IGGAGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVGNAGIGGTGGTGGVG
MUL_4367|M.ulcerans_Agy99 --------------------------------GGVGAASLGGDGGHAGAG
Mb1485c|M.bovis_AF2122/97 --------------------------------GNGGAGGAGGLVGNGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------------TGGVGGVGGVGATGGAG
TH_3810|M.thermoresistible__bu ---------------------------------VDGVDVVGG-NPDGGTP
MMAR_2823|M.marinum_M -----------------------------------GAMLVLA--VACGGG
MAV_2780|M.avium_104 -----------------------------------AAMLVLA--VGCGGG
MAB_3220|M.abscessus_ATCC_1997 -----------------------------------CAIALGAALAGCGTN
MLBr_01556|M.leprae_Br4923 ----------------------------------VREAEAGGITQHIGAY
Mflv_1054|M.gilvum_PYR-GCK TFAQPAPPPCFNAD------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 AMAEPAPPPCVNAD------------------------------------
Rv3508|M.tuberculosis_H37Rv GAGGAGAAAAAGSS--ATGGAGFAGGAGGEGGAGGNSGVGGTNGSGGAGG
MUL_4367|M.ulcerans_Agy99 GAGGEGLSGGFNTG--AAGGIGGAGGAGGTGGDSG--GVGGVNGDGGAGG
Mb1485c|M.bovis_AF2122/97 GAGGNGAPGAPPSGGDPNGGGGGAGGAGGKGGDGG--AQAGDGGAGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 GVGGKGIQGGQGLQ----GGQGGDGGTGGTGGDAT-----SMGEAGATGG
TH_3810|M.thermoresistible__bu GAHGESHTPGVYTD------RQGEDGEDGTG-----------------TG
MMAR_2823|M.marinum_M ENKGPSSTTPTTTP------------------------------------
MAV_2780|M.avium_104 HKGGPS-TTSTTTP------------------------------------
MAB_3220|M.abscessus_ATCC_1997 NDGGPTSTSTTTTT------------------------------------
MLBr_01556|M.leprae_Br4923 QVGVDLDGSERLITFIDTPGHEAFTAMRARGAKAT---------------
Mflv_1054|M.gilvum_PYR-GCK ------------------------GTPCTALGTAGPG-------------
MSMEG_5543|M.smegmatis_MC2_155 ------------------------GTPCSDIGTAGPG-------------
Rv3508|M.tuberculosis_H37Rv AGGKGGTGGAGGSGADNPTGAGFAGGAGGTGGAAGAGGAGGATGTGG-TG
MUL_4367|M.ulcerans_Agy99 GGGRGGDGGSSTS----TSGVGGAGGAGGNGGNAGFGVSAGGTG------
Mb1485c|M.bovis_AF2122/97 KGGNGGNGATGATG-LNGLGAGADGTDGGKGGNGGAGGGGGAGGQGGKAL
Mvan_1264|M.vanbaalenii_PYR-1 KGGNGGNGG--------------RGSLFGRGGNAGNG-------------
TH_3810|M.thermoresistible__bu IGGRGGNG----------------GSSSGTHPMAEDG-------------
MMAR_2823|M.marinum_M ------------------------TTTVPSS--PSSS-------------
MAV_2780|M.avium_104 ------------------------TTTPSTSVVPSTT-------------
MAB_3220|M.abscessus_ATCC_1997 ------------------------TTTTTTTITPAPS-------------
MLBr_01556|M.leprae_Br4923 -----------------DIAILVVAADDGVMPQTVEAIN-----------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GVVGATGSAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAG
MUL_4367|M.ulcerans_Agy99 ------GSAGDGGAGG---------------------------------G
Mb1485c|M.bovis_AF2122/97 AATHQDGSMGAGGAGGNG-------------------------------G
Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------G
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK -----------------------------------GAAGAIP--------
MSMEG_5543|M.smegmatis_MC2_155 -----------------------------------GATGQIP--------
Rv3508|M.tuberculosis_H37Rv AGGINGAGGAGGNG--GDGGDGATGAAGLGDNGGVGGDGGAGGAAGNGGN
MUL_4367|M.ulcerans_Agy99 AGGVDGVGGASGNG--GAAGAGGAGGSGIG----AGIDGGAGGAGGTGGA
Mb1485c|M.bovis_AF2122/97 AGGMGGDGGNGAKGTFDNGGDGVGGNGGNGGSRGIGGAGGIGGAGSTAGA
Mvan_1264|M.vanbaalenii_PYR-1 NGGTGGNGGNGGTG--GTGGNGGTGG--------TGGTGGIGGAGSTGG-
TH_3810|M.thermoresistible__bu -EHVKALDGR------------------------PGLDGGNGSHGGNGG-
MMAR_2823|M.marinum_M -----------------------------------PATESSPAP------
MAV_2780|M.avium_104 -----------------------------------PGG-GGTVP------
MAB_3220|M.abscessus_ATCC_1997 -----------------------------------GAPEGTPAP------
MLBr_01556|M.leprae_Br4923 ----------------------------------HAQAADVPIVVAVNKI
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv AGVGLTAKAGDGGAAGNGGNGG----AGGAGGAGDNNFNGGQGGAGGQGG
MUL_4367|M.ulcerans_Agy99 AGF-----PGGGGTTGAWGTGG----AGGAGGAG----------------
Mb1485c|M.bovis_AF2122/97 DGARG-ATPTSGGNGGTGGNGANATVAGGAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------TGGTGGTGGTGG----TGGTGGTG----------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 DKE-----------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv QGGLGGASTTSINANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGD
MUL_4367|M.ulcerans_Agy99 ------------------------------------GAGDHGGVGVNPGD
Mb1485c|M.bovis_AF2122/97 ------------------------------------GKGGNGGLVGNGGA
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------GTGGTGGTGGKGGT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK -------------------------------------------GGPAGEA
MSMEG_5543|M.smegmatis_MC2_155 -------------------------------------------GGPGGTA
Rv3508|M.tuberculosis_H37Rv AGSGGGGGFGGAAGKAGGGGNGGRGGDGGDGASGLGLGLSGFDGGQGGQG
MUL_4367|M.ulcerans_Agy99 SGTAG------------------------------------WAGGAGGAG
Mb1485c|M.bovis_AF2122/97 GGKGGDGMAGVAGSSPTTAGESG---------------TSGQNGGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGG-------------------------------------DGGTGGTG
TH_3810|M.thermoresistible__bu ------------------------------------------HGGRGGFL
MMAR_2823|M.marinum_M -------------------------------------------GGPSGTG
MAV_2780|M.avium_104 -------------------------------------------GGPTGGG
MAB_3220|M.abscessus_ATCC_1997 -------------------------------------------G-PTGGG
MLBr_01556|M.leprae_Br4923 ------------------------------------------GADPAKIR
.
Mflv_1054|M.gilvum_PYR-GCK GPGGASG------------------------------------AIPGGPA
MSMEG_5543|M.smegmatis_MC2_155 GPGGASG------------------------------------AIPGGPG
Rv3508|M.tuberculosis_H37Rv GAGGSAG-AGGINGAGGAGGNGGDGGDGATGAAGLGD--NGGVGGDGGAG
MUL_4367|M.ulcerans_Agy99 GAGGSAA-FNGVNGAGGAGGNGGAGGGGGAGASGIG---AGVAGGDGGTG
Mb1485c|M.bovis_AF2122/97 GAGGRGGDFGGDGGTGGAGGNGADGGAGGNGANGANATTPGAKGGDGGHG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGG----TGGTGGTGGTGGTGGAG------------DGLGGTGGTG
TH_3810|M.thermoresistible__bu GIGGSGG-------WGGHGGNGGD------------------TDADGGNG
MMAR_2823|M.marinum_M GPEGGGG------------------------------------GVPGGPT
MAV_2780|M.avium_104 GPGGGGG------------------------------------SIPGGPT
MAB_3220|M.abscessus_ATCC_1997 GPDGGSG------------------------------------AIPGGPT
MLBr_01556|M.leprae_Br4923 GQLTEYG---------------------------------LVAEDFGGDT
* . **
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GAAGNGGNAGVG--------LTAKAGDGGAAGNGGNGGAGGAGGAGDNNF
MUL_4367|M.ulcerans_Agy99 GTGG-------------------AAGTGGAAGTGGTGGAAGAAGS-----
Mb1485c|M.bovis_AF2122/97 GPGAQGGNGGQGGPGGLAGNLFGQNGIQGVGGSGGKGGAGGLAGDGGNGA
Mvan_1264|M.vanbaalenii_PYR-1 -------------------------GTGGFGGQGGQGGTG----------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 MFIDIS--------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK -------------------------------GEAGPGGASGAIP------
MSMEG_5543|M.smegmatis_MC2_155 -------------------------------GAAGPDGATGSIP------
Rv3508|M.tuberculosis_H37Rv NGGQGGAGGQGGQGGLGGASTTSINANGGAGGNGGTGGKGGAGGAGTLGV
MUL_4367|M.ulcerans_Agy99 ------------------------------AGDGGAGGAGGAGDDGSAGV
Mb1485c|M.bovis_AF2122/97 NG--------------------NFAFGDGNGGHGGNGGNPGAGGQGGSGG
Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------GTGGQGGLGGVGGTGGTG-
TH_3810|M.thermoresistible__bu -------------------------------GDGGNGGSAGRG-------
MMAR_2823|M.marinum_M -------------------------------GSGGPGGGGGSIP------
MAV_2780|M.avium_104 -------------------------------GGGGPGGGGGSIP------
MAB_3220|M.abscessus_ATCC_1997 -------------------------------GGGGPEGGSGSIP------
MLBr_01556|M.leprae_Br4923 ----------------------------AKVGTNIEALLEAVLLTADAAL
* .
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GGSGGTGGDGGDAGSGGGGGFGGAAGKAGGGGNGGVGGDGGEGASGLGLG
MUL_4367|M.ulcerans_Agy99 VS--------GDPG---------TAGKAGGAG------------------
Mb1485c|M.bovis_AF2122/97 AG--------STPGAKGAHGFTPTSGGDGGDGGNG--------------G
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 DLR-----------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK -----------GGPAGEAGPGGVSGSTNPGGVS-----------------
MSMEG_5543|M.smegmatis_MC2_155 -----------GGPAGTAGPDGATG-VIPGGPG-----------------
Rv3508|M.tuberculosis_H37Rv LSGFDGGQGGQGGAGGSAGAGGINGAGGAGGTGGAGGDGAPATLIGGPDG
MUL_4367|M.ulcerans_Agy99 ---------GAGGVGGNGVAGGVNGSGGAGGAG-----------------
Mb1485c|M.bovis_AF2122/97 HSQVVGGNGGDGGNGGNGGSAGTGGNGGRGGDGAFGGMSANATNPGENGP
Mvan_1264|M.vanbaalenii_PYR-1 ---------GTGGTGGQGGTGGTGGTGGTGGTG-----------------
TH_3810|M.thermoresistible__bu ------------GTGGLRGVFGINGGNGRAGLG-----------------
MMAR_2823|M.marinum_M -----------GGPTGGGGPG--GGGGTIPGVG-----------------
MAV_2780|M.avium_104 -----------GGPTGGGGPG--GGGGSIPGVG-----------------
MAB_3220|M.abscessus_ATCC_1997 -----------GGPTGGGGPE--GGGGHIPGVG-----------------
MLBr_01556|M.leprae_Br4923 ---------ANSGMEAQGVAIEAHLDRGRGPVATVLVQRG----------
* . .
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GDGGQGGIGGDGGNAGFGAGVPGDGGDGGNAGFGAGVPGDGGIGGTGGAG
MUL_4367|M.ulcerans_Agy99 -----------------------------------------------GAG
Mb1485c|M.bovis_AF2122/97 ---------------------------------------NGNPGGNGGAG
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------------------------GAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_1054|M.gilvum_PYR-GCK ------------------------------------------------GA
MSMEG_5543|M.smegmatis_MC2_155 ------------------------------------------------GT
Rv3508|M.tuberculosis_H37Rv GAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGA
MUL_4367|M.ulcerans_Agy99 GTGGAGASGVP-----------------------------ASVDGGDGGA
Mb1485c|M.bovis_AF2122/97 GAGGAGLNGGNGGAGGNGGLGGFGGNGAAG-----ANGVAVGAPGQPGGA
Mvan_1264|M.vanbaalenii_PYR-1 GDGGLGG------------------------------------LGGFGGV
TH_3810|M.thermoresistible__bu GRGXXX---------------------------------------XGGGV
MMAR_2823|M.marinum_M -----------------------------------------------GGG
MAV_2780|M.avium_104 -----------------------------------------------GGG
MAB_3220|M.abscessus_ATCC_1997 -----------------------------------------------GGH
MLBr_01556|M.leprae_Br4923 --------------------------------------------TLRIGD
*
Mflv_1054|M.gilvum_PYR-GCK AGPDG--------------------------------------VSGCIPN
MSMEG_5543|M.smegmatis_MC2_155 AGPGG--------------------------------------ASGCIPN
Rv3508|M.tuberculosis_H37Rv GGAGGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGR
MUL_4367|M.ulcerans_Agy99 GGAGG-----------AAGTGGSG------------GSAGNTGAGGAGGA
Mb1485c|M.bovis_AF2122/97 GGHGG-----------AGGNGGAGG--------NGGQGVVSDGAGGAGGA
Mvan_1264|M.vanbaalenii_PYR-1 GGTGG-----------QGGQGGPGG-----------------STGGAGGA
TH_3810|M.thermoresistible__bu GAAVR---------------------------------------SGNGVF
MMAR_2823|M.marinum_M GGPGG--------------------------------------GGGCIGN
MAV_2780|M.avium_104 GGPGG--------------------------------------GGGCVGN
MAB_3220|M.abscessus_ATCC_1997 GGPGG--------------------------------------GGGCVDN
MLBr_01556|M.leprae_Br4923 SVVAG------------------------------------DAYGRVRRM
. .
Mflv_1054|M.gilvum_PYR-GCK VGCATIPVG-----------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 VGCATIPAP-----------------------------------------
Rv3508|M.tuberculosis_H37Rv GGDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGINGAGGTGGTGGA
MUL_4367|M.ulcerans_Agy99 GGAGGSAASTGVNGDG-----------------------GAGGAGGVGGL
Mb1485c|M.bovis_AF2122/97 GGDGGAPGDGANGGNGQGAGAFAGGGGGRGGDGGNAGNAGAGGPGGTGST
Mvan_1264|M.vanbaalenii_PYR-1 GGQAGVAGKGGLFGGS-----------------------GSAGTAGVTGA
TH_3810|M.thermoresistible__bu SGGGGTPSAG------------------------------FGVPTTIQFP
MMAR_2823|M.marinum_M I-CGSYP-------------------------------------------
MAV_2780|M.avium_104 V-CGAYP-------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 VGCVSIP-------------------------------------------
MLBr_01556|M.leprae_Br4923 VDEHGVDIEAALPSSP-------------------VQVIGFTSVPGAGDN
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GGDGQNGTTGVASEGGAGGQGGD----GGQGGIGGAGGNAGFGAGVPGDG
MUL_4367|M.ulcerans_Agy99 GGDS-------AATAGGGGAGGD----GGKGGAGGAGVNGVGG----GDG
Mb1485c|M.bovis_AF2122/97 AGKAGPAG-SILHDGGNGGHGGHGAASGGNGGPGGHGGNGGNG-GTGANG
Mvan_1264|M.vanbaalenii_PYR-1 SGAS----------GGKGAQGAT----GAQGATGAQGATGATG----ASG
TH_3810|M.thermoresistible__bu AGSC------------------------TSRAVSREGIMPSSR-------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 FLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDSALKETSQLNL
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAA
MUL_4367|M.ulcerans_Agy99 GKGGTGGAGGAGGAGSDGIIPSNGGLGGNGGNGGNGGQ-----------A
Mb1485c|M.bovis_AF2122/97 GNGGIGGTGGAGSTGAKGVLGTNEGDGGDGGRGGNGGRGGNGGQGLTG-A
Mvan_1264|M.vanbaalenii_PYR-1 AQGSAGSAGSAGVAGSAGTTGAQGSAGTNGANGANGSQ------------
TH_3810|M.thermoresistible__bu -----AASARAGAACASSTSRSRRSFCCSRA-------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 ILKGDNAGTVEALEEALMGIQVDDEVALRVIDRG----------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv SGDGGNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGTAGN
MUL_4367|M.ulcerans_Agy99 FGDG------------------VGGAGGIGGKGGNAAIGTIVING-----
Mb1485c|M.bovis_AF2122/97 GGNGG-----------------TGGTPGNGGNGGNGASGDLVTSPGD---
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------GAAGKAGATGTTGATG-----------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 ----------------------VGGITETNVNLASASDAIIIGFN-----
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv AGIGGAGGRGGDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGINGA
MUL_4367|M.ulcerans_Agy99 ---------------------------------------------GVGGA
Mb1485c|M.bovis_AF2122/97 --------------------------------------GGGGGRGGDAGR
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------------AAGD
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 ----------------------------------------------VRAE
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GGTGGTGGAGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAG
MUL_4367|M.ulcerans_Agy99 GGSGGLGGATEDG-------------------------------------
Mb1485c|M.bovis_AF2122/97 GGDAGLGGSSGPG------------------------------------G
Mvan_1264|M.vanbaalenii_PYR-1 AGDPGSEAVDING-------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 GKATELASREGVEIR-----------------------------------
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv VPGDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTG
MUL_4367|M.ulcerans_Agy99 ------VGGVGCAGGAG---------------------GNGGRGDMLFT-
Mb1485c|M.bovis_AF2122/97 TPGDWGTGGTGGTGGTGGQGANG-----GLTGGRGGTGGNGGAGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 --------GAGGAGGAG---------------------GEGGEGG-----
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 ---------------------------YYLVIYQAIDDIEKALRGMLKPI
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv LASAASGDGGNGGAGGAGGNGGAGGLGGGGGTGGTNGNGGLGGGGGNGGA
MUL_4367|M.ulcerans_Agy99 ----------VGGSGGTGGDGGGGGSASGSGTGGSGGTGGVGGIGGDGKL
Mb1485c|M.bovis_AF2122/97 ---------HNGSQPGMGGNGGAGGFG-GNGFAGVGGRGGMGGSGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 ----------AGGAGGDGSEGGAGGSG-GAGGSGTGGAGGAGGSGGSGGS
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 YEENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTD
Mflv_1054|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GGAGGTPTGSGTEGTGGDGGDAGAGGNGGSATGVGNGGNGGDGGNGGDGG
MUL_4367|M.ulcerans_Agy99 G------------------------------------GFGGDGGDGGDGG
Mb1485c|M.bovis_AF2122/97 GDAG--------------------------PFGTGTGGTGGHGGQGGGGG
Mvan_1264|M.vanbaalenii_PYR-1 G------------------------------------GAGGSGGAAGDSD
TH_3810|M.thermoresistible__bu --------------------------------------------------
MMAR_2823|M.marinum_M --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 N------------------------------------LTVTSLRREKDDV
Mflv_1054|M.gilvum_PYR-GCK ------------------------------------------
MSMEG_5543|M.smegmatis_MC2_155 ------------------------------------------
Rv3508|M.tuberculosis_H37Rv NGAPGGFGGGAGAGGLG--GSGAGGGTDGDDGNGGSPGTDGS
MUL_4367|M.ulcerans_Agy99 FGVIGGQGGGGGFGGLG--GTGAGG-APSDKGINGEPGNPG-
Mb1485c|M.bovis_AF2122/97 FSILLGLGGLGGLGSPGSIATGTAGGAGGGGGFGGLGGGEFV
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------------
TH_3810|M.thermoresistible__bu ------------------------------------------
MMAR_2823|M.marinum_M ------------------------------------------
MAV_2780|M.avium_104 ------------------------------------------
MAB_3220|M.abscessus_ATCC_1997 ------------------------------------------
MLBr_01556|M.leprae_Br4923 TEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA-------