For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_3545 (-)

annotation: hypothetical protein MSMEG_3545
coordinates: 3604423 - 3605046
length: 207

MIVKTTTTRFVAAALTVGALGFGATAFGTPVASAGPAAPVPLKPGDGGCFPFCDGGPGKPGGPGGPGHGG
PGGPGGPGHGGPGGPGGHEGPGGPGRHDGPGPGGPGGPGRHDGPGGPGGPGWHDPGHGPDKGPWWANNRH
DWWDDRQGPPPWGWGPPPPVHWNGGPLPHTINYWGYNLNPVWHDGFRQWGVWLFGIWIPIFGVGFN*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3545--100% (207)hypothetical protein MSMEG_3545
M. smegmatis MC2 155MSMEG_5543-4e-1347.42% (97) hypothetical protein MSMEG_5543
M. smegmatis MC2 155MSMEG_5926-5e-1258.62% (58) putative secreted protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1485cPE_PGRS276e-1642.19% (128) PE-PGRS family protein
M. gilvum PYR-GCKMflv_4416-2e-1340.38% (104) hypothetical protein Mflv_4416
M. tuberculosis H37RvRv0109PE_PGRS12e-1542.40% (125) PE-PGRS family protein
M. leprae Br4923MLBr_01556infB7e-1034.72% (144) translation initiation factor IF-2
M. abscessus ATCC 19977MAB_1439c-6e-2433.50% (200) hypothetical protein MAB_1439c
M. marinum MMMAR_3811-2e-2047.33% (131) hypothetical protein MMAR_3811
M. avium 104MAV_2780-3e-1744.07% (118) hypothetical protein MAV_2780
M. thermoresistible (build 8)TH_3810-1e-1143.43% (99) PUTATIVE -
M. ulcerans Agy99MUL_0391-2e-1646.22% (119) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_5415-7e-1442.07% (145) hypothetical protein Mvan_5415

CLUSTAL 2.0.9 multiple sequence alignment


Mb1485c|M.bovis_AF2122/97           --------------------------------------MSLVIVAPETVA
Rv0109|M.tuberculosis_H37Rv         --------------------------------------MSLLITSPATVA
MUL_0391|M.ulcerans_Agy99           --------------------------------------MSLVRVAPQVVA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRES
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           AAALDVARIGSSIGVANSAAAGSTTSVLAAGADEVSAAIATLFGSHAREY
Rv0109|M.tuberculosis_H37Rv         AAATHLAGIGSALSTANAAAAAPTTALSVAGADEVSVLIAALFEAYAQEY
MUL_0391|M.ulcerans_Agy99           DGVGNLARIGSSIGVANAAAAAATTTMVPAGGDEVSAAVADG------QF
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_4416|M.gilvum_PYR-GCK          -------------------------------MNSPLRKALIAAGG-----
MAV_2780|M.avium_104                -----------------------------------------MFGG-----
MLBr_01556|M.leprae_Br4923          FGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAP
MMAR_3811|M.marinum_M               --------------------MKTYPRLAATGLAMVLG-------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           QAISTQVAAFHDRFAQTLSAAVGSYVSAEATNAAP---LATLEHNVLNAL
Rv0109|M.tuberculosis_H37Rv         QALSAQALAFHDQFVQALNMGAVCYAAAETANATPLQALQTVQQNVLTVV
MUL_0391|M.ulcerans_Agy99           QVLAEPVQTLGQAWLASP-----------------------AGELLDPLV
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_4416|M.gilvum_PYR-GCK          ------TTVLMLAVGCGGSDGR----------------------------
MAV_2780|M.avium_104                ------AAMLVLAVGCGGGHKG----------------------------
MLBr_01556|M.leprae_Br4923          VQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAA
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           NAPTQALLGRPLIGDGAAGAPGT-GQAGGAGGILWGNGGAGGSGAPGQVG
Rv0109|M.tuberculosis_H37Rv         NAPTQALLGRPIIGNGANGLPNT-GQDGGPGGLLFGNGGNGGSGGVDQAG
MUL_0391|M.ulcerans_Agy99           NAPFESLTGRELIGNGAAGVAGVDGGAGQAGGWLFGDGGPGAAATATSAA
TH_3810|M.thermoresistible__bu      --------------------------VDGDG----GSGGRTGLFSKLSRG
Mflv_4416|M.gilvum_PYR-GCK          -----------------------------EETTTSTTTESSVTTTTTTAP
MAV_2780|M.avium_104                -----------------------------GPSTTSTTTP-TTTPSTSVVP
MLBr_01556|M.leprae_Br4923          PHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAPRP
MMAR_3811|M.marinum_M               ----------------------------------LGLAGVGVASEAAAQP
MSMEG_3545|M.smegmatis_MC2_155      ---------------------------MMIVKTTTTRFVAAALTVGALGF
MAB_1439c|M.abscessus_ATCC_199      ----------------------------MNLKS----LVAQGAAVGALAM
Mvan_5415|M.vanbaalenii_PYR-1       ----------------------------MFTRRATITTATILALAGSVAI
                                                                                      

Mb1485c|M.bovis_AF2122/97           GAGGAAGLFGTGGAGGAGG-----AGAAGGAGGSGGWLLGNGGVGGAGGQ
Rv0109|M.tuberculosis_H37Rv         GNGGAAGLIGNGGSGGVGGP--GIAGSAGGAGGAGGLLFGNGGPGGAGG-
MUL_0391|M.ulcerans_Agy99           GRGGDAGLIGAGGAGGAGWANSGVAMMAGGAGGDGGLLLGDGGPGSPGAA
TH_3810|M.thermoresistible__bu      GDGGDGGLGGNGGHGGGTGIISLLSLAGNGGNGGNGYRTTDNN-------
Mflv_4416|M.gilvum_PYR-GCK          STPETTMAPETTGAPAPGDPSQP-----GGGGSIPGGPTGSGGPEGGG--
MAV_2780|M.avium_104                STTPGGGGTVPGGPTGGGGPG-------GGGGSIPGGPTGGGGPGGGG--
MLBr_01556|M.leprae_Br4923          SASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGRSDAGGGNY
MMAR_3811|M.marinum_M               G-APTQWCPGDFWDPGWGQNWDMGHCHDNWRGPGPNPQPGHAGPGGPGE-
MSMEG_3545|M.smegmatis_MC2_155      GATAFGTPVASAGPAAPVPLKPGDGGCFPFCDGGPGKPGGPGGPGHGGPG
MAB_1439c|M.abscessus_ATCC_199      GTLGMGAVPAFAQPVG----HP------AYTQDHPNRPHGDDDDDWGG--
Mvan_5415|M.vanbaalenii_PYR-1       GLSGGETTTLAQPPGG-----------VSSTSGPALPVQGPWDQCWGP--
                                    .              .                          .       

Mb1485c|M.bovis_AF2122/97           SLLGGATGGAGGNAGLFGVGGTGGPGGPGGPGGPGGPGGPGGVGGTGGAG
Rv0109|M.tuberculosis_H37Rv         ----------------IGTTGDGGPGGAGG----------NAIG------
MUL_0391|M.ulcerans_Agy99           S---------------FDPTVAGGAGGPGG----------DARG------
TH_3810|M.thermoresistible__bu      -------------------ALDGGHGGNGG-----------NVG------
Mflv_4416|M.gilvum_PYR-GCK          ---------------------GSIPGGPTG--------------------
MAV_2780|M.avium_104                ---------------------GSIPGGPTG--------------------
MLBr_01556|M.leprae_Br4923          R----------------GGGVGALPGGGSGG-------------------
MMAR_3811|M.marinum_M               --------------------PAPGQQGPGG--------------------
MSMEG_3545|M.smegmatis_MC2_155      GPGGPGHGGPGGPGGHEGPGGPGRHDGPGPGG------------------
MAB_1439c|M.abscessus_ATCC_199      ---------------HDG-----RHNN-----------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GLGGTLYGAGGHGGAGGPGPIGGVGGHGGVGGAAGLLGVGGHGGAGGHGA
Rv0109|M.tuberculosis_H37Rv         -----LFGSGGTGGMGG------VGGMGGVG-------------------
MUL_0391|M.ulcerans_Agy99           ------IGDGGRGGDGGPGATGAPGGRGSDGGP-----------------
TH_3810|M.thermoresistible__bu      --FFSLFNLGGAGGWGG---------------------------------
Mflv_4416|M.gilvum_PYR-GCK          --------SGGPDGGGG---------------------------------
MAV_2780|M.avium_104                --------GGGPGGGGG---------------------------------
MLBr_01556|M.leprae_Br4923          -------FRGRPGGGGH---------------------------------
MMAR_3811|M.marinum_M               --------PGGPGGPGE---------------------------------
MSMEG_3545|M.smegmatis_MC2_155      -------PGGPGRHDGP---------------------------------
MAB_1439c|M.abscessus_ATCC_199      ---------GNWRGDDS---------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       ------------NGWDP---------------------------------
                                                   .                                  

Mb1485c|M.bovis_AF2122/97           AGIAGAAGKGGIFPDGSNGGAGGDAGDGGTGGRGGWLAGAGGAGGDGGIG
Rv0109|M.tuberculosis_H37Rv         --------------------NGGNAGNGGTAG----LFGHGGAGGAGGIG
MUL_0391|M.ulcerans_Agy99           ------------------GGKGGNAGDYGTGG----TGGTGGIGGAGGPG
TH_3810|M.thermoresistible__bu      ---------------------SGVDGVDVVGG-----NPDGGTPGAHGES
Mflv_4416|M.gilvum_PYR-GCK          ----------------------SIPGGPTITG------GPGGGSGSIPGG
MAV_2780|M.avium_104                ----------------------SIPGVGGGGG------GPGGGGGCVG--
MLBr_01556|M.leprae_Br4923          ----------------------GGGGRPGQRG------GAAGAFGRPGGA
MMAR_3811|M.marinum_M               ----------------------GPGGPGGPGE------GPGGPGGPH---
MSMEG_3545|M.smegmatis_MC2_155      ----------------------GGPGGPGWHD-------PGHGPDKGPWW
MAB_1439c|M.abscessus_ATCC_199      ----------------------RRDRDRDWRD-------DGRWQDDRREW
Mvan_5415|M.vanbaalenii_PYR-1       ----------------------NCWGPGPWGP-------GGYGPGMTG--
                                                                            .   .     

Mb1485c|M.bovis_AF2122/97           GTGGAGGAGFSRALIVAGDNGGDGGNGGMGGAGGAGGPGGAGGLISLLGG
Rv0109|M.tuberculosis_H37Rv         SADGG--------------LGGGGGNGRFMGNGGVGGAGGYG-------A
MUL_0391|M.ulcerans_Agy99           SPGGT--------------PGAQGFRAGDAGNGGVGGIGGDGG--HIKGH
TH_3810|M.thermoresistible__bu      HTPGVY-------------TDRQGEDGEDGTGTGIGGRGGNGG-----SS
Mflv_4416|M.gilvum_PYR-GCK          P------------------------TINIPVP------------------
MAV_2780|M.avium_104                -------------------------NVCGAYP------------------
MLBr_01556|M.leprae_Br4923          PRRGRKSKR---------QKRQEYDSMQAPVVGGVRLPHGNGETIRLARG
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      ANNRH--------------DWWDDRQGPPPWGWGPPPPVHWNG------G
MAB_1439c|M.abscessus_ATCC_199      RDN----------------PWHYDQR--PPWGWAPPPRAEWRGPLPDRWG
Mvan_5415|M.vanbaalenii_PYR-1       -----------------------------PGGYGGPGMMGPGG-----YG
                                                                                      

Mb1485c|M.bovis_AF2122/97           QGAGGDGGDGGAGGVGGDRGAGANGNQAVNAGAGGAGGHGGDPGAGGAGG
Rv0109|M.tuberculosis_H37Rv         SGDGGNAGNGGLGGVFGD---------------------------GGAGG
MUL_0391|M.ulcerans_Agy99           GGAGGIGGTGGAGVIGGDG------------------------VIGGDGQ
TH_3810|M.thermoresistible__bu      SGTHPMAEDGEHVKALDGR----------------------------PGL
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ASLSDFAEKIDANPAALVQALFNLG---------------EMVTATQSVG
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      PLPHTINYWGYNLNPVWHDG------------------------------
MAB_1439c|M.abscessus_ATCC_199      PPPQAFDYWGHRVQPVWDDG------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       PGTMDPGQWGPGMMGPGQWG------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           TGGAGSTIGAHGAAGASPTSGGNGGAGGNGAHFSSGGKAGGNGGAGGAGG
Rv0109|M.tuberculosis_H37Rv         TGGLGDVN-------------------------------GGLAGIGGNAG
MUL_0391|M.ulcerans_Agy99           AGSAGEFPGDR----------------------------GGSGGAGARGG
TH_3810|M.thermoresistible__bu      DGGNGSH--------------------------------GGNGGHGGRGG
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          DETLELLGSEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGDEDELQVRPP
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      ---------------------------------------FRQWGVWLFGI
MAB_1439c|M.abscessus_ATCC_199      ---------------------------------------FRTWGFWLFGI
Mvan_5415|M.vanbaalenii_PYR-1       ---------------------------------------PGQYGPGMMGP
                                                                                      

Mb1485c|M.bovis_AF2122/97           LVGNGGAGGAGGNGAPGAPPSGGDPNGGGGGAGGAGGKGGDGGAQAGDGG
Rv0109|M.tuberculosis_H37Rv         FVRNGGAGGNG---------------------------------QLGSGA
MUL_0391|M.ulcerans_Agy99           NGGDGGAGGAGG-------------------------------HALAEGF
TH_3810|M.thermoresistible__bu      FLGIGGSGGWGG----------------------------------HGGN
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          VVTVMGHVDHGK-------------------------------TRLLDTI
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      WIPIFGVGFN----------------------------------------
MAB_1439c|M.abscessus_ATCC_199      WIPLVSVG------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       GPWDY---------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           AGGAGGKGGNGGNGATGATGLNGLGAGADGTDGGKGGNGGAGGGGGAGGQ
Rv0109|M.tuberculosis_H37Rv         VSSAGGMGGNGG--------------------------------------
MUL_0391|M.ulcerans_Agy99           HDGAAGTGGMGG--------------------------------------
TH_3810|M.thermoresistible__bu      GGDTDADGGNGG--------------------------------------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          RKANVREAEAGG--------------------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GGKALAATHQDGSMGAGGAGGNGGAGGMGGDGGNGAKGTFDNGGDGVGGN
Rv0109|M.tuberculosis_H37Rv         -----------------LVFGNGGPGGLGGPG------------------
MUL_0391|M.ulcerans_Agy99           ------------------DGGNGADGGDGHSGD-----------------
TH_3810|M.thermoresistible__bu      ------------------DGGNGGSAGRGGTGG-----------------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ----------------ITQHIGAYQVGVDLDGSERLITFIDTPG------
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GGNGGSRGIGGAGGIGGAGSTAGADGARGATPTSGGNGGTGGNGANATVA
Rv0109|M.tuberculosis_H37Rv         --------------------------------TSAGNGGMGGN-------
MUL_0391|M.ulcerans_Agy99           -----------------------------PSWRSGGDGGNGGN-------
TH_3810|M.thermoresistible__bu      --------------------------------LRGVFGINGGN-------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ------------------------------HEAFTAMRARGAKATDIAIL
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GGAGGAGGKGGNGGLVGNGGAGGKGGDGMAGVAGSSPTTAGESGTSGQNG
Rv0109|M.tuberculosis_H37Rv         -----------AVGLFGQGGAGGAGGSGFG--------------------
MUL_0391|M.ulcerans_Agy99           ------------GAYGGSGGQGGLNGDGATR-------------------
TH_3810|M.thermoresistible__bu      ----------------GRAGLGGRGXXX----------------------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          VVAADDGVMPQTVEAINHAQAADVPIVVAVN---------------KIDK
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GAGGAGGAGGRGGDFGGDGGTGGAGGNGADGGAGGNGANGANATTPGAKG
Rv0109|M.tuberculosis_H37Rv         ----AGIPGGRGGD------------------------------------
MUL_0391|M.ulcerans_Agy99           ---AAHGVQGTMGD------------------------------------
TH_3810|M.thermoresistible__bu      ---XGGGVGAAVRS------------------------------------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          EGADPAKIRG----------------------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GDGGHGGPGAQGGNGGQGGPGGLAGNLFGQNGIQGVGGSGGKGGAGGLAG
Rv0109|M.tuberculosis_H37Rv         ------------------------------------------GGSGGLIG
MUL_0391|M.ulcerans_Agy99           ------------------------------------------GGDGGDGG
TH_3810|M.thermoresistible__bu      -------------------------------------------GNGVFSG
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ----------------------------------------QLTEYGLVAE
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           DGGNGANGNFAFGDGNGGHGGNGGNPGAGGQGGSGGAGSTPGAKGAHGFT
Rv0109|M.tuberculosis_H37Rv         DGG------------------TGGGAGAGDAAAS----------------
MUL_0391|M.ulcerans_Agy99           NGS----------TTSDQVDIDGGNGGYGGWGFNGG--------------
TH_3810|M.thermoresistible__bu      GGG-------------------TPSAGFGVPTTIQFP-------------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          DFG-----------GDTMFIDISAKVGTNIEALLEAVLLT----------
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           PTSGGDGGDGGNGGH--SQVVGGNGGDGGNGGNGGSAGTGGNGGRGGDGA
Rv0109|M.tuberculosis_H37Rv         --------AGGNGGN--ARLIG-------------------NGGDGGPGM
MUL_0391|M.ulcerans_Agy99           --------NGGNGGDGGTRPKG--------------TLFFRSGGDGGFGG
TH_3810|M.thermoresistible__bu      ------------AGSCTSRAVS---------------------REGIMPS
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          -----ADAALDLRANSGMEAQG---------------VAIEAHLDRGRGP
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           FGGMSANATNPGENGPNGNPGGNGGAGGAGGAGLNGGNGGAGGNGGLGGF
Rv0109|M.tuberculosis_H37Rv         FG----------------GPGGAGGSG-----------------------
MUL_0391|M.ulcerans_Agy99           WGG----------NGYGGVGGGNGGAG-----------------------
TH_3810|M.thermoresistible__bu      ------------------SRAASARAG-----------------------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          VATVLVQRGTLRIGDSVVAGDAYGRVRRMVDEHG----------------
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GGNGAAGANGVAVGAPGQPGGAGGHGGAGGNGGAGGNGGQGVVSDGAGGA
Rv0109|M.tuberculosis_H37Rv         ---------GTIFGFAGTPGPS----------------------------
MUL_0391|M.ulcerans_Agy99           ---------GTAYTSGGVYAGGPVQPGTEGTGPSGDHGG-------FGGS
TH_3810|M.thermoresistible__bu      ---------AACASSTSRSRRSFCCSRA----------------------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------VDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADR
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GGAGGDGGAPGDGANGGNGQGAGAFAGGGGGRGGDGGNAGNAGAGGPGGT
Rv0109|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_0391|M.ulcerans_Agy99           GGIGGHGGQAP---------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          RSARKRNALAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEA
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GSTAGKAGPAGSILHDGGNGGHGGHGAASGGNGGPGGHGGNGGNGGTGAN
Rv0109|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_0391|M.ulcerans_Agy99           --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          LMGIQVDDEVALRVIDRGVGGITETNVNLASASDAIIIGFNVRAEGKATE
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GGNGGIGGTGGAGSTGAKGVLGTNEGDGGDGGRGGNGGRGGNGGQGLTGA
Rv0109|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_0391|M.ulcerans_Agy99           --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          LASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFRS
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GGNGGTGGTPGNGGNGGNGASGDLVTSPGDGGGGGRGGDAGRGGDAGLGG
Rv0109|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_0391|M.ulcerans_Agy99           --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          SKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEV
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           SSGPGGTPGDWGTGGTGGTGGTGGQGANGGLTGGRGGTGGNGGAGGTGGT
Rv0109|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_0391|M.ulcerans_Agy99           --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          REGFECGMTLGYSDIKEGDVIESYELVEKQRA------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           GHNGSQPGMGGNGGAGGFGGNGFAGVGGRGGMGGSGGTGGTGDAGPFGTG
Rv0109|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_0391|M.ulcerans_Agy99           --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           TGGTGGHGGQGGGGGFSILLGLGGLGGLGSPGSIATGTAGGAGGGGGFGG
Rv0109|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_0391|M.ulcerans_Agy99           --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mflv_4416|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2780|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MMAR_3811|M.marinum_M               --------------------------------------------------
MSMEG_3545|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1439c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_5415|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1485c|M.bovis_AF2122/97           LGGGEFV
Rv0109|M.tuberculosis_H37Rv         -------
MUL_0391|M.ulcerans_Agy99           -------
TH_3810|M.thermoresistible__bu      -------
Mflv_4416|M.gilvum_PYR-GCK          -------
MAV_2780|M.avium_104                -------
MLBr_01556|M.leprae_Br4923          -------
MMAR_3811|M.marinum_M               -------
MSMEG_3545|M.smegmatis_MC2_155      -------
MAB_1439c|M.abscessus_ATCC_199      -------
Mvan_5415|M.vanbaalenii_PYR-1       -------