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MIVKTTTTRFVAAALTVGALGFGATAFGTPVASAGPAAPVPLKPGDGGCFPFCDGGPGKPGGPGGPGHGG PGGPGGPGHGGPGGPGGHEGPGGPGRHDGPGPGGPGGPGRHDGPGGPGGPGWHDPGHGPDKGPWWANNRH DWWDDRQGPPPWGWGPPPPVHWNGGPLPHTINYWGYNLNPVWHDGFRQWGVWLFGIWIPIFGVGFN*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_3545 | - | - | 100% (207) | hypothetical protein MSMEG_3545 |
M. smegmatis MC2 155 | MSMEG_5543 | - | 4e-13 | 47.42% (97) | hypothetical protein MSMEG_5543 |
M. smegmatis MC2 155 | MSMEG_5926 | - | 5e-12 | 58.62% (58) | putative secreted protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1485c | PE_PGRS27 | 6e-16 | 42.19% (128) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_4416 | - | 2e-13 | 40.38% (104) | hypothetical protein Mflv_4416 |
M. tuberculosis H37Rv | Rv0109 | PE_PGRS1 | 2e-15 | 42.40% (125) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 7e-10 | 34.72% (144) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_1439c | - | 6e-24 | 33.50% (200) | hypothetical protein MAB_1439c |
M. marinum M | MMAR_3811 | - | 2e-20 | 47.33% (131) | hypothetical protein MMAR_3811 |
M. avium 104 | MAV_2780 | - | 3e-17 | 44.07% (118) | hypothetical protein MAV_2780 |
M. thermoresistible (build 8) | TH_3810 | - | 1e-11 | 43.43% (99) | PUTATIVE - |
M. ulcerans Agy99 | MUL_0391 | - | 2e-16 | 46.22% (119) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_5415 | - | 7e-14 | 42.07% (145) | hypothetical protein Mvan_5415 |
CLUSTAL 2.0.9 multiple sequence alignment Mb1485c|M.bovis_AF2122/97 --------------------------------------MSLVIVAPETVA Rv0109|M.tuberculosis_H37Rv --------------------------------------MSLLITSPATVA MUL_0391|M.ulcerans_Agy99 --------------------------------------MSLVRVAPQVVA TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRES MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 AAALDVARIGSSIGVANSAAAGSTTSVLAAGADEVSAAIATLFGSHAREY Rv0109|M.tuberculosis_H37Rv AAATHLAGIGSALSTANAAAAAPTTALSVAGADEVSVLIAALFEAYAQEY MUL_0391|M.ulcerans_Agy99 DGVGNLARIGSSIGVANAAAAAATTTMVPAGGDEVSAAVADG------QF TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------MNSPLRKALIAAGG----- MAV_2780|M.avium_104 -----------------------------------------MFGG----- MLBr_01556|M.leprae_Br4923 FGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAP MMAR_3811|M.marinum_M --------------------MKTYPRLAATGLAMVLG------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 QAISTQVAAFHDRFAQTLSAAVGSYVSAEATNAAP---LATLEHNVLNAL Rv0109|M.tuberculosis_H37Rv QALSAQALAFHDQFVQALNMGAVCYAAAETANATPLQALQTVQQNVLTVV MUL_0391|M.ulcerans_Agy99 QVLAEPVQTLGQAWLASP-----------------------AGELLDPLV TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK ------TTVLMLAVGCGGSDGR---------------------------- MAV_2780|M.avium_104 ------AAMLVLAVGCGGGHKG---------------------------- MLBr_01556|M.leprae_Br4923 VQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAA MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 NAPTQALLGRPLIGDGAAGAPGT-GQAGGAGGILWGNGGAGGSGAPGQVG Rv0109|M.tuberculosis_H37Rv NAPTQALLGRPIIGNGANGLPNT-GQDGGPGGLLFGNGGNGGSGGVDQAG MUL_0391|M.ulcerans_Agy99 NAPFESLTGRELIGNGAAGVAGVDGGAGQAGGWLFGDGGPGAAATATSAA TH_3810|M.thermoresistible__bu --------------------------VDGDG----GSGGRTGLFSKLSRG Mflv_4416|M.gilvum_PYR-GCK -----------------------------EETTTSTTTESSVTTTTTTAP MAV_2780|M.avium_104 -----------------------------GPSTTSTTTP-TTTPSTSVVP MLBr_01556|M.leprae_Br4923 PHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAPRP MMAR_3811|M.marinum_M ----------------------------------LGLAGVGVASEAAAQP MSMEG_3545|M.smegmatis_MC2_155 ---------------------------MMIVKTTTTRFVAAALTVGALGF MAB_1439c|M.abscessus_ATCC_199 ----------------------------MNLKS----LVAQGAAVGALAM Mvan_5415|M.vanbaalenii_PYR-1 ----------------------------MFTRRATITTATILALAGSVAI Mb1485c|M.bovis_AF2122/97 GAGGAAGLFGTGGAGGAGG-----AGAAGGAGGSGGWLLGNGGVGGAGGQ Rv0109|M.tuberculosis_H37Rv GNGGAAGLIGNGGSGGVGGP--GIAGSAGGAGGAGGLLFGNGGPGGAGG- MUL_0391|M.ulcerans_Agy99 GRGGDAGLIGAGGAGGAGWANSGVAMMAGGAGGDGGLLLGDGGPGSPGAA TH_3810|M.thermoresistible__bu GDGGDGGLGGNGGHGGGTGIISLLSLAGNGGNGGNGYRTTDNN------- Mflv_4416|M.gilvum_PYR-GCK STPETTMAPETTGAPAPGDPSQP-----GGGGSIPGGPTGSGGPEGGG-- MAV_2780|M.avium_104 STTPGGGGTVPGGPTGGGGPG-------GGGGSIPGGPTGGGGPGGGG-- MLBr_01556|M.leprae_Br4923 SASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGRSDAGGGNY MMAR_3811|M.marinum_M G-APTQWCPGDFWDPGWGQNWDMGHCHDNWRGPGPNPQPGHAGPGGPGE- MSMEG_3545|M.smegmatis_MC2_155 GATAFGTPVASAGPAAPVPLKPGDGGCFPFCDGGPGKPGGPGGPGHGGPG MAB_1439c|M.abscessus_ATCC_199 GTLGMGAVPAFAQPVG----HP------AYTQDHPNRPHGDDDDDWGG-- Mvan_5415|M.vanbaalenii_PYR-1 GLSGGETTTLAQPPGG-----------VSSTSGPALPVQGPWDQCWGP-- . . . Mb1485c|M.bovis_AF2122/97 SLLGGATGGAGGNAGLFGVGGTGGPGGPGGPGGPGGPGGPGGVGGTGGAG Rv0109|M.tuberculosis_H37Rv ----------------IGTTGDGGPGGAGG----------NAIG------ MUL_0391|M.ulcerans_Agy99 S---------------FDPTVAGGAGGPGG----------DARG------ TH_3810|M.thermoresistible__bu -------------------ALDGGHGGNGG-----------NVG------ Mflv_4416|M.gilvum_PYR-GCK ---------------------GSIPGGPTG-------------------- MAV_2780|M.avium_104 ---------------------GSIPGGPTG-------------------- MLBr_01556|M.leprae_Br4923 R----------------GGGVGALPGGGSGG------------------- MMAR_3811|M.marinum_M --------------------PAPGQQGPGG-------------------- MSMEG_3545|M.smegmatis_MC2_155 GPGGPGHGGPGGPGGHEGPGGPGRHDGPGPGG------------------ MAB_1439c|M.abscessus_ATCC_199 ---------------HDG-----RHNN----------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 GLGGTLYGAGGHGGAGGPGPIGGVGGHGGVGGAAGLLGVGGHGGAGGHGA Rv0109|M.tuberculosis_H37Rv -----LFGSGGTGGMGG------VGGMGGVG------------------- MUL_0391|M.ulcerans_Agy99 ------IGDGGRGGDGGPGATGAPGGRGSDGGP----------------- TH_3810|M.thermoresistible__bu --FFSLFNLGGAGGWGG--------------------------------- Mflv_4416|M.gilvum_PYR-GCK --------SGGPDGGGG--------------------------------- MAV_2780|M.avium_104 --------GGGPGGGGG--------------------------------- MLBr_01556|M.leprae_Br4923 -------FRGRPGGGGH--------------------------------- MMAR_3811|M.marinum_M --------PGGPGGPGE--------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------PGGPGRHDGP--------------------------------- MAB_1439c|M.abscessus_ATCC_199 ---------GNWRGDDS--------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 ------------NGWDP--------------------------------- . Mb1485c|M.bovis_AF2122/97 AGIAGAAGKGGIFPDGSNGGAGGDAGDGGTGGRGGWLAGAGGAGGDGGIG Rv0109|M.tuberculosis_H37Rv --------------------NGGNAGNGGTAG----LFGHGGAGGAGGIG MUL_0391|M.ulcerans_Agy99 ------------------GGKGGNAGDYGTGG----TGGTGGIGGAGGPG TH_3810|M.thermoresistible__bu ---------------------SGVDGVDVVGG-----NPDGGTPGAHGES Mflv_4416|M.gilvum_PYR-GCK ----------------------SIPGGPTITG------GPGGGSGSIPGG MAV_2780|M.avium_104 ----------------------SIPGVGGGGG------GPGGGGGCVG-- MLBr_01556|M.leprae_Br4923 ----------------------GGGGRPGQRG------GAAGAFGRPGGA MMAR_3811|M.marinum_M ----------------------GPGGPGGPGE------GPGGPGGPH--- MSMEG_3545|M.smegmatis_MC2_155 ----------------------GGPGGPGWHD-------PGHGPDKGPWW MAB_1439c|M.abscessus_ATCC_199 ----------------------RRDRDRDWRD-------DGRWQDDRREW Mvan_5415|M.vanbaalenii_PYR-1 ----------------------NCWGPGPWGP-------GGYGPGMTG-- . . Mb1485c|M.bovis_AF2122/97 GTGGAGGAGFSRALIVAGDNGGDGGNGGMGGAGGAGGPGGAGGLISLLGG Rv0109|M.tuberculosis_H37Rv SADGG--------------LGGGGGNGRFMGNGGVGGAGGYG-------A MUL_0391|M.ulcerans_Agy99 SPGGT--------------PGAQGFRAGDAGNGGVGGIGGDGG--HIKGH TH_3810|M.thermoresistible__bu HTPGVY-------------TDRQGEDGEDGTGTGIGGRGGNGG-----SS Mflv_4416|M.gilvum_PYR-GCK P------------------------TINIPVP------------------ MAV_2780|M.avium_104 -------------------------NVCGAYP------------------ MLBr_01556|M.leprae_Br4923 PRRGRKSKR---------QKRQEYDSMQAPVVGGVRLPHGNGETIRLARG MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 ANNRH--------------DWWDDRQGPPPWGWGPPPPVHWNG------G MAB_1439c|M.abscessus_ATCC_199 RDN----------------PWHYDQR--PPWGWAPPPRAEWRGPLPDRWG Mvan_5415|M.vanbaalenii_PYR-1 -----------------------------PGGYGGPGMMGPGG-----YG Mb1485c|M.bovis_AF2122/97 QGAGGDGGDGGAGGVGGDRGAGANGNQAVNAGAGGAGGHGGDPGAGGAGG Rv0109|M.tuberculosis_H37Rv SGDGGNAGNGGLGGVFGD---------------------------GGAGG MUL_0391|M.ulcerans_Agy99 GGAGGIGGTGGAGVIGGDG------------------------VIGGDGQ TH_3810|M.thermoresistible__bu SGTHPMAEDGEHVKALDGR----------------------------PGL Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ASLSDFAEKIDANPAALVQALFNLG---------------EMVTATQSVG MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 PLPHTINYWGYNLNPVWHDG------------------------------ MAB_1439c|M.abscessus_ATCC_199 PPPQAFDYWGHRVQPVWDDG------------------------------ Mvan_5415|M.vanbaalenii_PYR-1 PGTMDPGQWGPGMMGPGQWG------------------------------ Mb1485c|M.bovis_AF2122/97 TGGAGSTIGAHGAAGASPTSGGNGGAGGNGAHFSSGGKAGGNGGAGGAGG Rv0109|M.tuberculosis_H37Rv TGGLGDVN-------------------------------GGLAGIGGNAG MUL_0391|M.ulcerans_Agy99 AGSAGEFPGDR----------------------------GGSGGAGARGG TH_3810|M.thermoresistible__bu DGGNGSH--------------------------------GGNGGHGGRGG Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 DETLELLGSEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGDEDELQVRPP MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 ---------------------------------------FRQWGVWLFGI MAB_1439c|M.abscessus_ATCC_199 ---------------------------------------FRTWGFWLFGI Mvan_5415|M.vanbaalenii_PYR-1 ---------------------------------------PGQYGPGMMGP Mb1485c|M.bovis_AF2122/97 LVGNGGAGGAGGNGAPGAPPSGGDPNGGGGGAGGAGGKGGDGGAQAGDGG Rv0109|M.tuberculosis_H37Rv FVRNGGAGGNG---------------------------------QLGSGA MUL_0391|M.ulcerans_Agy99 NGGDGGAGGAGG-------------------------------HALAEGF TH_3810|M.thermoresistible__bu FLGIGGSGGWGG----------------------------------HGGN Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 VVTVMGHVDHGK-------------------------------TRLLDTI MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 WIPIFGVGFN---------------------------------------- MAB_1439c|M.abscessus_ATCC_199 WIPLVSVG------------------------------------------ Mvan_5415|M.vanbaalenii_PYR-1 GPWDY--------------------------------------------- Mb1485c|M.bovis_AF2122/97 AGGAGGKGGNGGNGATGATGLNGLGAGADGTDGGKGGNGGAGGGGGAGGQ Rv0109|M.tuberculosis_H37Rv VSSAGGMGGNGG-------------------------------------- MUL_0391|M.ulcerans_Agy99 HDGAAGTGGMGG-------------------------------------- TH_3810|M.thermoresistible__bu GGDTDADGGNGG-------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 RKANVREAEAGG-------------------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 GGKALAATHQDGSMGAGGAGGNGGAGGMGGDGGNGAKGTFDNGGDGVGGN Rv0109|M.tuberculosis_H37Rv -----------------LVFGNGGPGGLGGPG------------------ MUL_0391|M.ulcerans_Agy99 ------------------DGGNGADGGDGHSGD----------------- TH_3810|M.thermoresistible__bu ------------------DGGNGGSAGRGGTGG----------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ----------------ITQHIGAYQVGVDLDGSERLITFIDTPG------ MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 GGNGGSRGIGGAGGIGGAGSTAGADGARGATPTSGGNGGTGGNGANATVA Rv0109|M.tuberculosis_H37Rv --------------------------------TSAGNGGMGGN------- MUL_0391|M.ulcerans_Agy99 -----------------------------PSWRSGGDGGNGGN------- TH_3810|M.thermoresistible__bu --------------------------------LRGVFGINGGN------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ------------------------------HEAFTAMRARGAKATDIAIL MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 GGAGGAGGKGGNGGLVGNGGAGGKGGDGMAGVAGSSPTTAGESGTSGQNG Rv0109|M.tuberculosis_H37Rv -----------AVGLFGQGGAGGAGGSGFG-------------------- MUL_0391|M.ulcerans_Agy99 ------------GAYGGSGGQGGLNGDGATR------------------- TH_3810|M.thermoresistible__bu ----------------GRAGLGGRGXXX---------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 VVAADDGVMPQTVEAINHAQAADVPIVVAVN---------------KIDK MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 GAGGAGGAGGRGGDFGGDGGTGGAGGNGADGGAGGNGANGANATTPGAKG Rv0109|M.tuberculosis_H37Rv ----AGIPGGRGGD------------------------------------ MUL_0391|M.ulcerans_Agy99 ---AAHGVQGTMGD------------------------------------ TH_3810|M.thermoresistible__bu ---XGGGVGAAVRS------------------------------------ Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 EGADPAKIRG---------------------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 GDGGHGGPGAQGGNGGQGGPGGLAGNLFGQNGIQGVGGSGGKGGAGGLAG Rv0109|M.tuberculosis_H37Rv ------------------------------------------GGSGGLIG MUL_0391|M.ulcerans_Agy99 ------------------------------------------GGDGGDGG TH_3810|M.thermoresistible__bu -------------------------------------------GNGVFSG Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ----------------------------------------QLTEYGLVAE MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 DGGNGANGNFAFGDGNGGHGGNGGNPGAGGQGGSGGAGSTPGAKGAHGFT Rv0109|M.tuberculosis_H37Rv DGG------------------TGGGAGAGDAAAS---------------- MUL_0391|M.ulcerans_Agy99 NGS----------TTSDQVDIDGGNGGYGGWGFNGG-------------- TH_3810|M.thermoresistible__bu GGG-------------------TPSAGFGVPTTIQFP------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 DFG-----------GDTMFIDISAKVGTNIEALLEAVLLT---------- MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 PTSGGDGGDGGNGGH--SQVVGGNGGDGGNGGNGGSAGTGGNGGRGGDGA Rv0109|M.tuberculosis_H37Rv --------AGGNGGN--ARLIG-------------------NGGDGGPGM MUL_0391|M.ulcerans_Agy99 --------NGGNGGDGGTRPKG--------------TLFFRSGGDGGFGG TH_3810|M.thermoresistible__bu ------------AGSCTSRAVS---------------------REGIMPS Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -----ADAALDLRANSGMEAQG---------------VAIEAHLDRGRGP MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 FGGMSANATNPGENGPNGNPGGNGGAGGAGGAGLNGGNGGAGGNGGLGGF Rv0109|M.tuberculosis_H37Rv FG----------------GPGGAGGSG----------------------- MUL_0391|M.ulcerans_Agy99 WGG----------NGYGGVGGGNGGAG----------------------- TH_3810|M.thermoresistible__bu ------------------SRAASARAG----------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 VATVLVQRGTLRIGDSVVAGDAYGRVRRMVDEHG---------------- MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 GGNGAAGANGVAVGAPGQPGGAGGHGGAGGNGGAGGNGGQGVVSDGAGGA Rv0109|M.tuberculosis_H37Rv ---------GTIFGFAGTPGPS---------------------------- MUL_0391|M.ulcerans_Agy99 ---------GTAYTSGGVYAGGPVQPGTEGTGPSGDHGG-------FGGS TH_3810|M.thermoresistible__bu ---------AACASSTSRSRRSFCCSRA---------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 --------VDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADR MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 GGAGGDGGAPGDGANGGNGQGAGAFAGGGGGRGGDGGNAGNAGAGGPGGT Rv0109|M.tuberculosis_H37Rv -------------------------------------------------- MUL_0391|M.ulcerans_Agy99 GGIGGHGGQAP--------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 RSARKRNALAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEA MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 GSTAGKAGPAGSILHDGGNGGHGGHGAASGGNGGPGGHGGNGGNGGTGAN Rv0109|M.tuberculosis_H37Rv -------------------------------------------------- MUL_0391|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 LMGIQVDDEVALRVIDRGVGGITETNVNLASASDAIIIGFNVRAEGKATE MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 GGNGGIGGTGGAGSTGAKGVLGTNEGDGGDGGRGGNGGRGGNGGQGLTGA Rv0109|M.tuberculosis_H37Rv -------------------------------------------------- MUL_0391|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 LASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFRS MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 GGNGGTGGTPGNGGNGGNGASGDLVTSPGDGGGGGRGGDAGRGGDAGLGG Rv0109|M.tuberculosis_H37Rv -------------------------------------------------- MUL_0391|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 SKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEV MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 SSGPGGTPGDWGTGGTGGTGGTGGQGANGGLTGGRGGTGGNGGAGGTGGT Rv0109|M.tuberculosis_H37Rv -------------------------------------------------- MUL_0391|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 REGFECGMTLGYSDIKEGDVIESYELVEKQRA------------------ MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 GHNGSQPGMGGNGGAGGFGGNGFAGVGGRGGMGGSGGTGGTGDAGPFGTG Rv0109|M.tuberculosis_H37Rv -------------------------------------------------- MUL_0391|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 TGGTGGHGGQGGGGGFSILLGLGGLGGLGSPGSIATGTAGGAGGGGGFGG Rv0109|M.tuberculosis_H37Rv -------------------------------------------------- MUL_0391|M.ulcerans_Agy99 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_4416|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MMAR_3811|M.marinum_M -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1439c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5415|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 LGGGEFV Rv0109|M.tuberculosis_H37Rv ------- MUL_0391|M.ulcerans_Agy99 ------- TH_3810|M.thermoresistible__bu ------- Mflv_4416|M.gilvum_PYR-GCK ------- MAV_2780|M.avium_104 ------- MLBr_01556|M.leprae_Br4923 ------- MMAR_3811|M.marinum_M ------- MSMEG_3545|M.smegmatis_MC2_155 ------- MAB_1439c|M.abscessus_ATCC_199 ------- Mvan_5415|M.vanbaalenii_PYR-1 -------