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TLNNDYAFGAEERERLVAIESLWDAGSQALLAEVGLSAGWNCLELGAGGGSLVEWMVEQGATVTAIDLDT RFVEHLRSDTVTVVESDIRRTELPQAAFDLVHARLVLEHLVDRRQVFDRLIAALRPGGWLVVEDFNWSTF AFEGFDGDEVVNAVEACLTLMRRSGVEVNYGRRMVADLVDAGFVAVRGEGRVRIVDSTAPGFAFFKHSLE SLSDDIVAAGLISAEQVEFVRRRLEQDARLTTPMMVAALGRRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5353 | - | - | 100% (254) | putative methyltransferase |
| M. smegmatis MC2 155 | MSMEG_2350 | - | 6e-08 | 32.08% (106) | hypothetical protein MSMEG_2350 |
| M. smegmatis MC2 155 | MSMEG_4303 | - | 2e-07 | 29.37% (126) | methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0862 | - | 3e-09 | 25.59% (211) | hypothetical protein Mb0862 |
| M. gilvum PYR-GCK | Mflv_2895 | - | 4e-07 | 30.08% (133) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv0839 | - | 4e-09 | 25.59% (211) | hypothetical protein Rv0839 |
| M. leprae Br4923 | MLBr_01713 | - | 3e-08 | 33.33% (105) | hypothetical protein MLBr_01713 |
| M. abscessus ATCC 19977 | MAB_1977 | - | 1e-07 | 32.32% (99) | putative methyltransferase |
| M. marinum M | MMAR_4799 | - | 1e-10 | 27.70% (213) | hypothetical protein MMAR_4799 |
| M. avium 104 | MAV_0854 | - | 7e-09 | 26.54% (211) | methyltransferase-UbiE family protein |
| M. thermoresistible (build 8) | TH_0144 | - | 8e-08 | 28.38% (148) | methyltransferase |
| M. ulcerans Agy99 | MUL_0368 | - | 4e-10 | 29.76% (168) | hypothetical protein MUL_0368 |
| M. vanbaalenii PYR-1 | Mvan_2098 | - | 1e-07 | 31.25% (128) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01713|M.leprae_Br4923 MSAFVPDVPNRIPDDPSSIDSTAFHGMLTLTGERTI---PDLDIENYWFR
Mvan_2098|M.vanbaalenii_PYR-1 MSASVTDGP---TEDP---------APMALTGERTV---PGVAEENYWFR
Mb0862|M.bovis_AF2122/97 ------------MNDKRRAIYTHGYHESVLRSHRRR---TAENSAGYLL-
Rv0839|M.tuberculosis_H37Rv ------------MNDKRRAIYTHGYHESVLRSHRRR---TAENSAGYLL-
MMAR_4799|M.marinum_M ------------MNDERRAVYTHGHHESVLRGHRQR---TVANSAGYLS-
MUL_0368|M.ulcerans_Agy99 ------------MNDERRAVYTHGHHESVLRGHRQR---TVANSAGYLS-
MAV_0854|M.avium_104 ------------MNDQHRATYTHGHHESVLRSHRRR---TAEDSAGYLL-
Mflv_2895|M.gilvum_PYR-GCK -----------MTDVKQHWEERYSQRDRIWSGHVNR---WLAEVAAPLK-
TH_0144|M.thermoresistible__bu ----------------------------MWSGRVNA---RLAEVAGELP-
MSMEG_5353|M.smegmatis_MC2_155 ----------MTLNNDYAFGAEERERLVAIESLWDAGSQALLAEVG----
MAB_1977|M.abscessus_ATCC_1997 ---------MDPAEHARHTRDVYDRLAPVWSATTDDGPFNGLLERPALR-
.
MLBr_01713|M.leprae_Br4923 RHQVVYQWLAQRCTGCEVLEAGCGEGYGADLIVDVAY--RVIAVDYDEAT
Mvan_2098|M.vanbaalenii_PYR-1 RHEVVYRRLVDRCAGRDVLEAGCGEGYGAALIAEVAR--SVIGLDYDESA
Mb0862|M.bovis_AF2122/97 ---------PYLVPGLSVLDVGCGPGTITVDLAARVVPGSVTGVEPTDDA
Rv0839|M.tuberculosis_H37Rv ---------PYLVPGLSVLDVGCGPGTITVDLAARVVPGSVTGVEPTDDA
MMAR_4799|M.marinum_M ---------PHLRAGLSVLDIGCGPGTITVDLAARVAPATVTAVEPTDAA
MUL_0368|M.ulcerans_Agy99 ---------PHLRAGLSVLDIGCGPGTITVDLAARVAPGTVTAVEPTDAA
MAV_0854|M.avium_104 ---------AHLTPGLSVLDVGCGPGTITADLAARVAPGQVTAVDQAADV
Mflv_2895|M.gilvum_PYR-GCK ---------PGR-----ALDLGCGEGGDTLWLAEHG--WEVVGVDISDTA
TH_0144|M.thermoresistible__bu ---------PGR-----ALDVGCGEGADAMWLAERG--WQVTAVDISQTA
MSMEG_5353|M.smegmatis_MC2_155 -----------LSAGWNCLELGAGGGSLVEWMVEQG--ATVTAIDLDTRF
MAB_1977|M.abscessus_ATCC_1997 ------SLIPRPLAGRSVLDAGCGSGAQCAWLLGEG--ADVTGLDLSPAM
*: *.* * : * .::
MLBr_01713|M.leprae_Br4923 VAHVRSRYPR-----VQVMQANLIELPLADASVDVVVNFQVIEHLW-NQA
Mvan_2098|M.vanbaalenii_PYR-1 VAHVRARYPR-----VDMRHGNLAALPLPTASVDVVVNFQVIEHLW-DQG
Mb0862|M.bovis_AF2122/97 LSLARAEAQLHRLSNISFTTSDVHKLDFPDDAFDVVHAHQVLQHVA-DPV
Rv0839|M.tuberculosis_H37Rv LSLARAEAQLHRLSNISFTTSDVHKLDFPDDAFDVVHAHQVLQHVA-DPV
MMAR_4799|M.marinum_M LNLARAEVQRCDVSNVAFVTSDVHALDFPDDVFDVVHAHQVLQHVA-DPV
MUL_0368|M.ulcerans_Agy99 LNLGRAEAQRCDVSNVAFVTSDVHALDFPDDVFDVVHAHQVLQHVA-DPV
MAV_0854|M.avium_104 LEVARAEAEQRNLSNVSFGTADVHRLDFADDTFDVVHAHQVLQHLS-DPV
Mflv_2895|M.gilvum_PYR-GCK LRRAAEEADKRGLADRVQLRQTDLSASFPDGVFDLVSAQFLQSMVHLDRE
TH_0144|M.thermoresistible__bu LDRAAAEAASRGLT--IDFQRHELPATFPDGQFELVSAHFLHSEVELDRV
MSMEG_5353|M.smegmatis_MC2_155 VEHLRSDTVT-------VVESDIRRTELPQAAFDLVHARLVLEHLV-DRR
MAB_1977|M.abscessus_ATCC_1997 VDQARQRCGS---AAKLMVADLADDLPLEPRSFDGVTCSLALHYLR-DWQ
: : .: * : :
MLBr_01713|M.leprae_Br4923 QFVSECARVLRPSGLLMVSTPNRITFSPG-RDTSINPFHTRELN---ADE
Mvan_2098|M.vanbaalenii_PYR-1 QFVAECARVLRPGGVLLMSTPNRITFSPG-RDTPVNPFHTRELN---AAE
Mb0862|M.bovis_AF2122/97 RALQEMRRVCTPGGIVAARDADYSGFIWF-PKLPALDRWLDLYERAARAN
Rv0839|M.tuberculosis_H37Rv RALQEMRRVCTPGGIVAARDADYSGFIWF-PKLPALDRWLDLYERAARAN
MMAR_4799|M.marinum_M QALREMKRVCAPGGLVAARDADYAGFIWY-PQLPALDHWLKLYQRAARAN
MUL_0368|M.ulcerans_Agy99 QALREMKRVGAPGGLVAARDADYAGFIWY-PQLPALDHWLQLYQRAARAN
MAV_0854|M.avium_104 AALREMRRVCRPGGIVAVRDADYAGFIWY-PELPALDLWRDLYRRVARAN
Mflv_2895|M.gilvum_PYR-GCK RIFAAAARAVAPGGVLIVVDHAAA--------------------------
TH_0144|M.thermoresistible__bu RILRRAAEAVVPGGLLLIVDHGAP--------------------------
MSMEG_5353|M.smegmatis_MC2_155 QVFDRLIAALRPGGWLVVEDFNWSTFAFEGFDGDEVVNAVEACLTLMRRS
MAB_1977|M.abscessus_ATCC_1997 VPLASFARILRPGGWVVISLDHPFGAPLP---------------------
. *.* :
MLBr_01713|M.leprae_Br4923 LTQLLITADFSEVAMYGLFHGPRLKEMDARHGGSIIDAQIARAVSNAPWP
Mvan_2098|M.vanbaalenii_PYR-1 LTELIESADFAMEAMLGVFHGRRLAEIDARHGGSVIDAQIARALADAPWP
Mb0862|M.bovis_AF2122/97 GGEPDAGRRLLSWARAAGFDDVTPTASVWCFATASAREWWGLVWADRILQ
Rv0839|M.tuberculosis_H37Rv GGEPDAGRRLLSWARAAGFDDVTPTASVWCFATASAREWWGLVWADRILQ
MMAR_4799|M.marinum_M GGEPDAGRRLLSWARQAGFADITPTGSMWCYATDEMRAWWGGMWAERILR
MUL_0368|M.ulcerans_Agy99 GGEPDAGRRLLSWARQAGFADITPTGSMWCYATDEMRAWWGGMWADRILR
MAV_0854|M.avium_104 RGEPDAGRRLLSWARQAGFDDITPTGSLWCYATPETRDWWGGMWADRILH
Mflv_2895|M.gilvum_PYR-GCK ----------PPWAPPEVHEHRFSTVDEVLATIDLGEGSWERLRADVVER
TH_0144|M.thermoresistible__bu ----------PPWAPDHVHEFEFPSAQEVVESLQLPEGQWELLRAEPVKR
MSMEG_5353|M.smegmatis_MC2_155 GVEVNYGRRMVADLVDAGFVAVRGEGRVRIVDSTAPGFAFFKHSLESLSD
MAB_1977|M.abscessus_ATCC_1997 ---DQRGGYFQHQLVSDTWNKADVEVTQHFWRRPLGQVADAFADAGLLIE
MLBr_01713|M.leprae_Br4923 PELVADVAAVTAADFDIIEASAGPEASDGRDVDESLDLIAIAVRR--
Mvan_2098|M.vanbaalenii_PYR-1 AELLADIESVTIEDFDLVPADG-----THRDIDDSLDLVAIAVRT--
Mb0862|M.bovis_AF2122/97 SDLAHQLVDSGLATAAQLEEISTAWREWAAAPDGWLAIPHGEILCRA
Rv0839|M.tuberculosis_H37Rv SDLAHQLVDSGLATAAQLEEISTAWREWAAAPDGWLAIPHGEILCRA
MMAR_4799|M.marinum_M SDLSAQLLGSGMASAADLEAISQAWRDWAAAPDGWLGIPNGEILCRV
MUL_0368|M.ulcerans_Agy99 SDLSAQLLGSGMASAADLEAISQAWRDWAAAPDGWLGIPNGEILCRV
MAV_0854|M.avium_104 STVARDLVSLGLAAREQLEEISAAWREWAAAPDGWIAIPHGEIICRA
Mflv_2895|M.gilvum_PYR-GCK DAIGPDGEAGVLRDNLIVVRRCA------------------------
TH_0144|M.thermoresistible__bu DAVGPDGQQGTLIDNVIMLRRR-------------------------
MSMEG_5353|M.smegmatis_MC2_155 DIVAAGLISAEQVEFVRRRLEQDARLTTPMMVAALGRRP--------
MAB_1977|M.abscessus_ATCC_1997 RISEPRPSAEAIRRFPAELRNVVDSPSFIVYRLRYWGAPA-------