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VDPAEHARHTRDVYDRLAPVWSATTDDGPFNGLLERPALRSLIPRPLAGRSVLDAGCGSGAQCAWLLGEG ADVTGLDLSPAMVDQARQRCGSAAKLMVADLADDLPLEPRSFDGVTCSLALHYLRDWQVPLASFARILRP GGWVVISLDHPFGAPLPDQRGGYFQHQLVSDTWNKADVEVTQHFWRRPLGQVADAFADAGLLIERISEPR PSAEAIRRFPAELRNVVDSPSFIVYRLRYWGAPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1977 | - | - | 100% (244) | putative methyltransferase |
| M. abscessus ATCC 19977 | MAB_4103c | - | 3e-10 | 37.76% (98) | methyltransferase |
| M. abscessus ATCC 19977 | MAB_0868c | - | 3e-09 | 29.20% (137) | hypothetical protein MAB_0868c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1550 | - | 5e-11 | 39.39% (99) | methyltransferase |
| M. gilvum PYR-GCK | Mflv_4692 | - | 1e-09 | 32.65% (98) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv1523 | - | 5e-11 | 39.39% (99) | methyltransferase |
| M. leprae Br4923 | MLBr_02273 | ubiE | 2e-08 | 36.61% (112) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. marinum M | MMAR_2640 | - | 7e-11 | 42.45% (106) | methyltransferase |
| M. avium 104 | MAV_3903 | - | 2e-10 | 30.22% (225) | methyltransferase, UbiE/COQ5 family protein |
| M. smegmatis MC2 155 | MSMEG_3286 | - | 8e-31 | 38.53% (218) | methyltransferase |
| M. thermoresistible (build 8) | TH_2937 | - | 2e-09 | 27.00% (200) | PUTATIVE Methyltransferase type 11 |
| M. ulcerans Agy99 | MUL_3115 | - | 5e-11 | 42.45% (106) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4620 | - | 8e-12 | 35.45% (110) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_1977|M.abscessus_ATCC_1997 -------------------------MDPAEHARHTRDVYDRLAPVWSATT
MSMEG_3286|M.smegmatis_MC2_155 ----------------------------MPDTVGPQPQYETFADEFLDHA
Mb1550|M.bovis_AF2122/97 -------------------------MTITALTVTLPLLWRRLTTAGVKYA
Rv1523|M.tuberculosis_H37Rv -------------------------MTITALTVTLPLLWRRLTTAGVKYA
Mflv_4692|M.gilvum_PYR-GCK --------------------------------MTSSTFWS-----AGRYD
TH_2937|M.thermoresistible__bu ----------------------------------VTTNWA-----AGRYE
MMAR_2640|M.marinum_M MSRTAERADRLSIRYPVCSPTAQVRRSCRGRRMVARVAESDRRRWDRRYA
MUL_3115|M.ulcerans_Agy99 ---------------------------------MARVAESDRRRWDRRYA
MLBr_02273|M.leprae_Br4923 -----------------MPPGSVDVVSRAALDKDPRDVVAMFDDVAHRYD
MAV_3903|M.avium_104 -------MTRSTDAVPTPHATAEQVEAARHDSKLAQVLYHDWEAETYDEK
Mvan_4620|M.vanbaalenii_PYR-1 ------------------------------------------MSFVVASE
MAB_1977|M.abscessus_ATCC_1997 DDGPFNGLLERPALRSLIPRPLAG-------RSVLDAGCGSG--------
MSMEG_3286|M.smegmatis_MC2_155 RDGFYNAHYDRPACLALIG-DVAG-------RTILDAACGPG--------
Mb1550|M.bovis_AF2122/97 DQGHFVGSAGVPAADAGGRDAASEQIARWTQTCTVVLVCGHGPAKWAFRS
Rv1523|M.tuberculosis_H37Rv DQGHFVGSAGVPAADAGGRDAASEQIARWTQTCTVVLVCGHGPAKWAFRS
Mflv_4692|M.gilvum_PYR-GCK AVGDRIAPIAREVVDAADARRP------LRDAAVVDLACGTG--------
TH_2937|M.thermoresistible__bu AVGERIAPIADEVLDAAARRTP------LRGATLVDLACGTG--------
MMAR_2640|M.marinum_M SLGPAAVSAARPPALLQAHLKLVP-----TAGRALDLGCGQG--------
MUL_3115|M.ulcerans_Agy99 SLGPAAVSAVRPPALLQAHLKLVP-----AAGRALDLGCGQG--------
MLBr_02273|M.leprae_Br4923 LTNTVLSLGQDRYWRRATRSALRIG----PGQKVLDLAAGTA--------
MAV_3903|M.avium_104 WSISYDQRCIDYARGRFDAIVPEHVLRELPYDRALELGCGTG--------
Mvan_4620|M.vanbaalenii_PYR-1 AYGRFMGRYAEPLAEAFVAFAGVG-----VGDKVLDVGCGPG--------
: .* .
MAB_1977|M.abscessus_ATCC_1997 ----------AQCAWLLGEGADVTG--LDLSPAMVDQARQRCGSAAKLMV
MSMEG_3286|M.smegmatis_MC2_155 ----------LYAEELAKRGASLIG--FDQSPRMVELARARVP-SGDFRV
Mb1550|M.bovis_AF2122/97 WCTSRSCDTLPVALRYRLQSNPLVG--KLTTKYFLPLGTRQVGDHVVFFN
Rv1523|M.tuberculosis_H37Rv WCTSRSCDTLPVALRYRLQSNPLVG--KLTTKYFLPLGTRQVGDHVVFFN
Mflv_4692|M.gilvum_PYR-GCK ----------SAALDAAARGARVTG--VDITPELIAIAAERDGAAAVRWR
TH_2937|M.thermoresistible__bu ----------SAALSATARGAAVTG--VDITSELIALAAGKPGGSTVTWV
MMAR_2640|M.marinum_M ----------LGAVWLARRGLDVLG--LDISPVAIAQARDLAERSGVSAR
MUL_3115|M.ulcerans_Agy99 ----------LGAVWLARRGLDVLG--LDISPVAIAQARDLAERSGVSAR
MLBr_02273|M.leprae_Br4923 ----------VSTAELSKSGAWCVA--ADFSVRMLATG----GARKVPKV
MAV_3903|M.avium_104 ----------FFLLNLIQSGVARRGSVTDLSPGMVKVATRNGQSLGLDID
Mvan_4620|M.vanbaalenii_PYR-1 ----------ALTARLRSVGADIAA--IDPSPPFIDAIRRSFPDVDVRQG
. . : :
MAB_1977|M.abscessus_ATCC_1997 ADLADDLP-------------------LEP-RSFDGVTCSLALHYLRDWQ
MSMEG_3286|M.smegmatis_MC2_155 HDLAGPLD-------------------WLPSQSVDAVLLALALEYVDDRT
Mb1550|M.bovis_AF2122/97 FGYEEDPPMALPLSESDEPNRYCIQLYHQTASQVDLTGKEVLEVSCGA-G
Rv1523|M.tuberculosis_H37Rv FGYEEDPPMALPLSESDEPNRYCIQLYHQTASQVDLTGKEVLEVSCGA-G
Mflv_4692|M.gilvum_PYR-GCK TGDASDT--------------------GLPATSFDAAVSNMGIIFVEP-A
TH_2937|M.thermoresistible__bu TADAADT--------------------GLKTASFDVAVSNMGIIFVPP-D
MMAR_2640|M.marinum_M CCFDVVD---------------------LDDGLPDGPPVDVIVCHNFRDR
MUL_3115|M.ulcerans_Agy99 CRFDVVD---------------------LDDGLPDGPPVDLIVCHNFRDR
MLBr_02273|M.leprae_Br4923 AADATQLP--------------------FSDGVFDAVTISFGLRNIADYQ
MAV_3903|M.avium_104 GRVADAEG------------------IPYEDDTFDLVVGHAVLHHIPDVE
Mvan_4620|M.vanbaalenii_PYR-1 PAE--ELP--------------------YDSAAFDAALAQLVVHFMTDPV
*
MAB_1977|M.abscessus_ATCC_1997 VPLASFARILRPGGWVVISL------------------------------
MSMEG_3286|M.smegmatis_MC2_155 AMLREFHRVLRPAGALVLSR------------------------------
Mb1550|M.bovis_AF2122/97 GGASYIARNLGPASYTGLDLNPASIDLCRAKHRLPGLQFVQGDAQNLPFP
Rv1523|M.tuberculosis_H37Rv GGASYIARNLGPASYTGLDLNPASIDLCRAKHRLPGLQFVQGDAQNLPFP
Mflv_4692|M.gilvum_PYR-GCK RQVAEVVRLLKPGGVFAFSS------------------WVRSVSN--PLF
TH_2937|M.thermoresistible__bu RQVAELARLLKPGGVLSFSA------------------WIRTDEN--PFS
MMAR_2640|M.marinum_M RLDAAIIDRLAPGGLVALVA------------------------------
MUL_3115|M.ulcerans_Agy99 RLDAAIIERLAPGGLVALVA------------------------------
MLBr_02273|M.leprae_Br4923 AALREMARVTRPGGQLVVCEFS----------------------------
MAV_3903|M.avium_104 LSLREVIRVLRPGGRFVFAGEPTSAG------------DVYARELSTLTW
Mvan_4620|M.vanbaalenii_PYR-1 AGLRQMSRVTRPGGVVAACVWDG---------------------------
. *..
MAB_1977|M.abscessus_ATCC_1997 --------DHPFGAPLPDQRGGYFQHQLVSDT---WNKADVEVTQHFWRR
MSMEG_3286|M.smegmatis_MC2_155 --------MHPTGDWLR-HGGNYFETRVVEET---WSRG---WNVRYWLA
Mb1550|M.bovis_AF2122/97 DESFDAVVNVEASHQYPDFRGFLAEVARVLRPGGHFLYTDSRRNPVVAEW
Rv1523|M.tuberculosis_H37Rv DESFDAVVNVEASHQYPDFRGFLAEVARVLRPGGHFLYTDSRRNPVVAEW
Mflv_4692|M.gilvum_PYR-GCK DPVLAVLGPPATSTFSPDQWGDEAVLTERLGS--QFDGVDVRRGDHRWEF
TH_2937|M.thermoresistible__bu DPVAEVLGPPPAG-FSPDQWGDAETLTERLTP--HFDAIDLIRGLHPWEF
MMAR_2640|M.marinum_M ----------------------LSEVGAAAGT---------------YRA
MUL_3115|M.ulcerans_Agy99 ----------------------LSEVGAAAGT---------------YRA
MLBr_02273|M.leprae_Br4923 -----------------------TPTNALVAN---------VYTEYLMRA
MAV_3903|M.avium_104 RIATNVTKLPGLGSWRRPQAELDESSRAAALEAIVDLHTFTPGDLERMAA
Mvan_4620|M.vanbaalenii_PYR-1 --PTGALAPFWDAVHVVDPEAEDEALLSGARSGHLTELFEAAGLRDVVED
MAB_1977|M.abscessus_ATCC_1997 PLGQVADAFADAGLLIERISEPRPSAEAIRRFPAELRNVVDSPS------
MSMEG_3286|M.smegmatis_MC2_155 PLERTCSELRDAGFLIEELREPRPTEEAARRDPQAYQRLAQAPEGFMTIR
Mb1550|M.bovis_AF2122/97 EAALADAPLRTISQRDIGAQAKRGLDANTARSQEAIG--RRAPVLLAGLT
Rv1523|M.tuberculosis_H37Rv EAALADAPLRTISQRDIGAQAKRGLDANTARSQEAIG--RRAPVLLAGLT
Mflv_4692|M.gilvum_PYR-GCK ESMPAAMRFLTSESPMHVETFRRAETSQRARLAAEFEDALRPHLEPSGSV
TH_2937|M.thermoresistible__bu DSPATALHFLRTESPVHVEIFRRAGPARRERLAAAFRSALRPHAGPAGTV
MMAR_2640|M.marinum_M APGELSAAFAELDPIAAGEGDGRAWLLARA--------------------
MUL_3115|M.ulcerans_Agy99 APGELSTAFAELDPIAAGEGDGRAWLLARA--------------------
MLBr_02273|M.leprae_Br4923 LPQVARLVSSNPDAYIYLAESIRAWPDQVTLACQLSRTGWASPRWRNLTG
MAV_3903|M.avium_104 NAGATEVRTVSEEFTAAMFGWPVRTFEASVPPGRLGWGWAKFAFNGWKTL
Mvan_4620|M.vanbaalenii_PYR-1 SIAVDVVHPTFEQWWEPYTYGVGPAGDYVQQLDDEGRARLESAARERLGK
MAB_1977|M.abscessus_ATCC_1997 -FIVYRLRYWGAPA--------------
MSMEG_3286|M.smegmatis_MC2_155 AVPDFRLRRPAAGR--------------
Mb1550|M.bovis_AF2122/97 RCAVRVLDWDLRRGGGFSYRIYLFAKD-
Rv1523|M.tuberculosis_H37Rv RCAVRVLDWDLRRGGGFSYRIYLFAKD-
Mflv_4692|M.gilvum_PYR-GCK AFLSPYVVVTATLRG-------------
TH_2937|M.thermoresistible__bu GFTAPYVIVTARRRG-------------
MMAR_2640|M.marinum_M ----------------------------
MUL_3115|M.ulcerans_Agy99 ----------------------------
MLBr_02273|M.leprae_Br4923 GIVALHAADKPVR---------------
MAV_3903|M.avium_104 SWVDANIWRRVVPKGWFYNVMVTGVKPT
Mvan_4620|M.vanbaalenii_PYR-1 GPFTVTAVAWAARGTA------------