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MPEGNPAKPLDGFRVLDFTQNVAGPLAGQVLADLGAEVIKVEAPGGEAARHITAVLPHRPPLATYFLPNN RGKKSVSVDLSTDTARRQILRLADTADVVLEGFRPGVMERMGLGPEDLRARNPKLIYARLSAFGGNGPHG TRPGVDLMVAAEAGMTTGMPTPDGKPQIIPFQLVDNASGHVLAQAVLAALLNRERHGVADTVRVAMYDVA VGLQANQLTMHLNRPSSDAPKRPEQTPAGARRKRVAFATQPSDAFRAADGYLLISAYVPKHWQRLCEIIG QPDLLDDERFIDQRARAINYAELTEELESALAAKTAAQWVELLHEGGLMACLAYTWKQVVTTPLFAENEL ALQVDSGDDAVTVIRTPARYSSFSAVLADPPPATGEHNETLLGES
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2621 | - | - | 100% (395) | acyl-CoA transferase |
| M. ulcerans Agy99 | MUL_1046 | - | 1e-42 | 29.62% (395) | acyl-CoA transferase |
| M. ulcerans Agy99 | MUL_2446 | - | 4e-42 | 32.24% (397) | hypothetical protein MUL_2446 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 0.0 | 78.32% (392) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_4116 | - | 2e-45 | 32.50% (400) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv3272 | - | 0.0 | 78.57% (392) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4651c | - | 4e-41 | 31.61% (348) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_1267 | - | 0.0 | 98.99% (395) | acyl-CoA transferase |
| M. avium 104 | MAV_4237 | - | 1e-177 | 78.54% (396) | YfdE protein |
| M. smegmatis MC2 155 | MSMEG_6773 | - | 7e-57 | 35.73% (389) | CaiB/BaiF family protein |
| M. thermoresistible (build 8) | TH_4341 | - | 2e-44 | 33.25% (397) | PUTATIVE putative L-carnitine dehydratase/bile acid-inducible |
| M. vanbaalenii PYR-1 | Mvan_2229 | - | 6e-47 | 33.58% (405) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2621|M.ulcerans_Agy99 ----MPEGNPAKPLDGFRVLDFTQNVAGPLAGQVLADLGAEVIKVEAPG-
MMAR_1267|M.marinum_M ----MPEGNPAKPLDGFRVLDFTQNVAGPLAGQVLADLGAEVIKVEAPG-
MAV_4237|M.avium_104 MPHETPNGKPPKPLDGFRVLDFTQNIAGPMAGQVLADLGAEVIKIEAPI-
Mb3300|M.bovis_AF2122/97 ----MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPG-
Rv3272|M.tuberculosis_H37Rv ----MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPG-
MSMEG_6773|M.smegmatis_MC2_155 -------------MRGLRVLDFTHVVAGPLCTMTLADLGADVVKIEPPA-
MAB_4651c|M.abscessus_ATCC_199 ---------MTGALDGIRVLELGTLIAGPFAGRLLGDMGAEVLKIEPP--
Mflv_4116|M.gilvum_PYR-GCK -----MAG----PLEGIRVVELGVWVAGPAAGGILADWGADVVKIEPPT-
Mvan_2229|M.vanbaalenii_PYR-1 -----MAG----PLEGLRVVELGVWVAGPAAGGILADWGADVVKIEPPG-
TH_4341|M.thermoresistible__bu --MGDRAGRSVQVLEGIRVLELSGFAYVPSAGAILADWGADVIKVEHPAH
: *:**::: * . * * **:*:*:* *
MUL_2621|M.ulcerans_Agy99 GEAAR----HITAVLPHRPPLATYFLPNNRGKKSVSVDLSTDTARRQILR
MMAR_1267|M.marinum_M GEAAR----HITAVLPHRPPLATYFLPNNRGKKSVSVDLSTDTARRQILR
MAV_4237|M.avium_104 GEAAR----HITAVLPGRPPLATLFLPHNRGKKSVLADLRDDEAKQRILR
Mb3300|M.bovis_AF2122/97 GEAAR----QITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLR
Rv3272|M.tuberculosis_H37Rv GEAAR----QITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLR
MSMEG_6773|M.smegmatis_MC2_155 GEIGR----RIG--PPWRDGQSVIWQSVNRNKRSLTLDLKTPAGRRAARR
MAB_4651c|M.abscessus_ATCC_199 GAPDP----LRTWGQAEVDGHHVFWTVHARNKKAITLDLRTEAGRALFLD
Mflv_4116|M.gilvum_PYR-GCK GDPARTFGRMLGIPPQDRHHVSPPFQMDNRGKRSVVLDLASPDGRRSARE
Mvan_2229|M.vanbaalenii_PYR-1 GDPARTFGRMLGIQPQDRHHVSPPFQMDNRGKRSVVLDLATADGQSSARE
TH_4341|M.thermoresistible__bu GDPSR--GITIGGIPPGTGGFTFMWELANRGKRSVGIDVSTDDGRRLVLE
* : *.*::: *: .:
MUL_2621|M.ulcerans_Agy99 LADTADVVLEGFRPGVMERMGLGPEDLRARNPKLIYARLSAFGGNGPHGT
MMAR_1267|M.marinum_M LADTADVVLEGFRPGVMERMGLGPEDLRARNPKLIYARLSAFGGNGPHGT
MAV_4237|M.avium_104 LVDTADVVLEGFRPGVMERMGLGPEELQGRNPRLVYARLSAYGGNGPEGS
Mb3300|M.bovis_AF2122/97 LADTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGS
Rv3272|M.tuberculosis_H37Rv LADTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGS
MSMEG_6773|M.smegmatis_MC2_155 MARQADVVVESFRPGVMTDLDLGYDTLASANPALVYCSISAFGQAGPASD
MAB_4651c|M.abscessus_ATCC_199 LVDKSDVIVENFRPGTLERWGLGYDVLAQRNKGIILVRVSGYGQTGPDAH
Mflv_4116|M.gilvum_PYR-GCK LIDGADVFVTNIRVGGLRRIGLDFEALAAANPRLVYGLITGYGTEGPDAD
Mvan_2229|M.vanbaalenii_PYR-1 LLAGADVFLTNIRTGALRRIGLDFPAVAAANPQLIYGLITGYGSDGPDAD
TH_4341|M.thermoresistible__bu LAKSADVFLTSYLPGVREKLRITEDDIRGVNPSIVYAVGSGQGHHGPENA
: :**.: * : : * :: :. * **
MUL_2621|M.ulcerans_Agy99 RPGVDLMVAAEAG-MTTGMPTPDGKPQIIPF-QLVDNASGHVLAQAVLAA
MMAR_1267|M.marinum_M RPGVDLMVAAEAG-MTTGMPTPDGKPQIIPF-QLVDNASGHVLAQAVLAA
MAV_4237|M.avium_104 RPGVDLMVAAESG-MTTGMPTPTGKPQIIPF-QLVDAASGHVLAQAVLAA
Mb3300|M.bovis_AF2122/97 RPGIDLVVAAEAG-MTTGMPTPEGKPQIIPF-QLVDNASGHVLAQAVLAA
Rv3272|M.tuberculosis_H37Rv RPGIDLVVAAEAG-MTTGMPTPEGKPQIIPF-QLVDNASGHVLAQAVLAA
MSMEG_6773|M.smegmatis_MC2_155 RPGVDGIMQAVTG-LMSTLGEPESGPAKVQV-PAADMVTGYLASIAVLAA
MAB_4651c|M.abscessus_ATCC_199 KAGYASVAEAASG-LRHLNGFPGGPPPRMAL-SIGDTLAGMFAAQGALAA
Mflv_4116|M.gilvum_PYR-GCK RPAFDVAAFWARAGLAHLLTRPGDVPPFQRG-GMGDHMAGMTLAGAICAA
Mvan_2229|M.vanbaalenii_PYR-1 RPAYDVAAFWARSGLAHLLTRPGEAPPFQRG-GMGDHMAGMTLAGAVCAA
TH_4341|M.thermoresistible__bu AGGFDQTSFWYRTGMASALTEAGGHPPELPGPGFGDLSSGVALAGGISAA
. : . * * :* : . **
MUL_2621|M.ulcerans_Agy99 LLNRERHGVADTVRVAMYDVAVGLQANQLTMHLNRPSSDAPKRPEQTPAG
MMAR_1267|M.marinum_M LLNRERHGVADTVRVAMYDVAVGLQANQLTMHLNRPSSDAPKRPEQTPAG
MAV_4237|M.avium_104 LLNRERHGVADVVRVAMYDVAVSLQASQLTIHLNKPNADH-KPSDSASKP
Mb3300|M.bovis_AF2122/97 LLHRERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQ-PKPEPAPKA
Rv3272|M.tuberculosis_H37Rv LLHRERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQ-PKPEPAPKA
MSMEG_6773|M.smegmatis_MC2_155 LHEVRDGGRGQHLDVSLYNATILLQQIGFTSYLASG-----------AEP
MAB_4651c|M.abscessus_ATCC_199 LYRRTVTGRGQVVDAALTESCLAVQESTIPDYDVGRVVRG-------PSG
Mflv_4116|M.gilvum_PYR-GCK LVARARTGTGQLVSTSLYRQGAYTVSFDLTTFLITGNP-----------I
Mvan_2229|M.vanbaalenii_PYR-1 LVARARTGAGQLVSTSLYRQGAYTVSFDLNTFLLTGHP-----------I
TH_4341|M.thermoresistible__bu LLHRERTGAGVAVHGSLLATGMWMMQPSIVATEVTGEPE----------F
* * . : :: :
MUL_2621|M.ulcerans_Agy99 ARRKRVAFATQPSDAFRAADG--YLLISAYVPKHWQRLCEIIGQPDLLDD
MMAR_1267|M.marinum_M ARRKRVAFATQPSDAFRAADG--YLLISAYVPKHWQRLCEIIGRPDLLDD
MAV_4237|M.avium_104 KRRKGVGFATQPSDAFKAADG--YLVISAYVPKHWDKLCEVIGRPDLRDD
Mb3300|M.bovis_AF2122/97 KRRKGVGFATQPSDAFRTADG--YIVISAYVPKHWQKLCYLIGRPDLVED
Rv3272|M.tuberculosis_H37Rv KRRKGVGFATQPSDAFRTADG--YIVISAYVPKHWQKLCYLIGRPDLVED
MSMEG_6773|M.smegmatis_MC2_155 QRLGSAAPYAAPNEALPTADG--WIMIAAYDPARWNALCDALGAPDLSSD
MAB_4651c|M.abscessus_ATCC_199 TRLEG----IAPSNIYQSADGS-WVVIAANQDTVFRRLCEAMGRPELSSD
Mflv_4116|M.gilvum_PYR-GCK AIGQREVMGNPCMNNYSAADGKRFWLVGLQGDRHWPALCAAVQRPDWPTD
Mvan_2229|M.vanbaalenii_PYR-1 AIGQRETMGNPCMNNYTAADGRRFWLVGLQGERHWPALCAAVERTDWLSD
TH_4341|M.thermoresistible__bu RWLDRFETTNPLVNSYRTADGRYIGLTVLHADKHWREFCEAIGHPELADD
: :*** : : :* : .: *
MUL_2621|M.ulcerans_Agy99 ERFIDQRARAINYAELTEELESALAAKTAAQWVELLHEGG-LMACLAYTW
MMAR_1267|M.marinum_M ERFIDQRARAINYAELTEELESALAAKTAAQWVELLHEGG-LMACLAYTW
MAV_4237|M.avium_104 ERFADQRSRALNYPELTEELEKALAAKTADEWVRLLQAAG-LMACHAYTW
Mb3300|M.bovis_AF2122/97 QRFAEQRSRSINYAELTAELELALASKTATEWVQLLQANG-LMACLAHTW
Rv3272|M.tuberculosis_H37Rv QRFAEQRSRSINYAELTAELELALASKTATEWVQLLQANG-LMACLAHTW
MSMEG_6773|M.smegmatis_MC2_155 ARFATNDDRVRNRPALRTELGRLLRARTTQVWLDVLSARD-ILCAPVNGY
MAB_4651c|M.abscessus_ATCC_199 ARFANHVARGRNQDDLDAIIAQWAAQRLPTDIIDVLSAAG-VIAGPINTV
Mflv_4116|M.gilvum_PYR-GCK ERFATGRARAANAAELIAELDAIFARRTLAEWTEVFAAHPDLFWSPINSM
Mvan_2229|M.vanbaalenii_PYR-1 ERFATGRARAANAVELIAELDTVFAGKTLEEWAEVFSGQPDLFWSPINSM
TH_4341|M.thermoresistible__bu ERFADHDARAANSAACVKLLDEIFATRTLEHWKAVLSAQG-AQWAVIQQC
** * * : : ::
MUL_2621|M.ulcerans_Agy99 KQVVTTPLFAENELALQVD-------------SGDDAVTVIRTPARYSSF
MMAR_1267|M.marinum_M KQVVTTPLFAENELALQVG-------------SGDDAVTVIRTPARYSSF
MAV_4237|M.avium_104 KQVVGTPLFAENELALQVG-------------EGADAVTVIRTPARYSSF
Mb3300|M.bovis_AF2122/97 KQVVDTPLFAESDLTLEVG-------------RGADTITVIRTPARYASF
Rv3272|M.tuberculosis_H37Rv KQVVDTPLFAENDLTLEVG-------------RGADTITVIRTPARYASF
MSMEG_6773|M.smegmatis_MC2_155 GQVVASPEYAASGLHRPIGPIDTPGLVLGPSQPAAPPDTAPPAPGQHSAE
MAB_4651c|M.abscessus_ATCC_199 ADVVQDPQLKAREMLVEHFDERLGRSVLG---PGVVPVLSESPGGVRNAG
Mflv_4116|M.gilvum_PYR-GCK EDVIGDEQFHAAGGIVYVPD------------DEAGSVPMVATPADFHGT
Mvan_2229|M.vanbaalenii_PYR-1 EDVIADEQFHASGGIVYVPD------------SDGGAVPMVATPADFHGT
TH_4341|M.thermoresistible__bu AETRSDPQVVANGYLQAVDY------------GGGRSISLVPAPVQYGDG
:. . .
MUL_2621|M.ulcerans_Agy99 SAVLA----DPPPATGEHNET------LLGES-------
MMAR_1267|M.marinum_M SAVLA----EPPAATGEHNET------LLGES-------
MAV_4237|M.avium_104 EAASAGWATDPPPALGQHTEE------YLGAPQTAS---
Mb3300|M.bovis_AF2122/97 RAVVT----DPPPTAGEHNAV------FLARP-------
Rv3272|M.tuberculosis_H37Rv RAVVT----DPPPTAGEHNAV------FLARP-------
MSMEG_6773|M.smegmatis_MC2_155 VLAEYGLSEDEVAALIEHGVV------NDVAPSRAAS--
MAB_4651c|M.abscessus_ATCC_199 PARPGQDNDDVYVGLLGKSAQ------DIERLRAEGVL-
Mflv_4116|M.gilvum_PYR-GCK PAQIRCSAPELGAHTEEVLT-------ELAQRTNRST--
Mvan_2229|M.vanbaalenii_PYR-1 PAEVRCAAPELGEHTEEVLA-------ELAQWTNRSM--
TH_4341|M.thermoresistible__bu PPRLR-PAPELGANTEEVLLDNGLEWEEIERLKDQRVIT
: