For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MQTERELLTEICERIDRHARGDMHTRIDGLLLSKAAGSSRPDYTVTEPLLVVMARGGKRIMVGDEVYEYR TGEMLIVTASLPVTGHYLETDQPSLGMGLELRPAALAELALRAPARPALRTGSAGSAIAVGNADAEMLDA AARLLRLLDRPDDAPVLAPLVEQEILWRLLTGPHGDTVRQIALADSALTYINRAITWMRDNYASPVRIED LARMAGMSTSVFHRHFRAVTAMSPLQFQKRIRLQQARSLLVSQPGDVAAVAHLVGYDSASQFTREYRRMF GAPPGQDAARLRAAHAPEPALLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4655 | - | - | 100% (303) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_3998 | - | 2e-10 | 28.77% (146) | MmsAB operon regulatory protein |
| M. smegmatis MC2 155 | MSMEG_6839 | - | 1e-09 | 28.12% (96) | transcriptional regulator, AraC family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3863 | - | 2e-07 | 31.07% (103) | AraC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5242 | - | 1e-11 | 31.61% (193) | helix-turn-helix domain-containing protein |
| M. tuberculosis H37Rv | Rv3833 | - | 2e-07 | 31.07% (103) | AraC family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2899c | - | 1e-09 | 29.79% (94) | AraC family transcriptional regulator |
| M. marinum M | MMAR_2855 | - | 2e-06 | 34.15% (82) | transcriptional regulatory protein |
| M. avium 104 | MAV_0193 | - | 8e-08 | 33.00% (100) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_4270 | - | 2e-08 | 30.28% (142) | PUTATIVE putative transcriptional regulator, AraC family |
| M. ulcerans Agy99 | MUL_2902 | - | 8e-06 | 32.93% (82) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3612 | - | 3e-11 | 33.04% (115) | helix-turn-helix domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2855|M.marinum_M -------------------------------------------------M
MUL_2902|M.ulcerans_Agy99 -------------------------------------------------M
MAB_2899c|M.abscessus_ATCC_199 MRSARGPHSGEPGRSGEPHSGRLGRSGEPHSGRLGRSGEPHSGRLGRSGE
Mb3863|M.bovis_AF2122/97 --------------------------------------------------
Rv3833|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0193|M.avium_104 --------------------------------------------------
Mvan_3612|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5242|M.gilvum_PYR-GCK -----------------------------------------MDVLMSLLR
MSMEG_4655|M.smegmatis_MC2_155 --------------------------------------------MQTERE
TH_4270|M.thermoresistible__bu ----------------------------------MKDGPLLELGRVRDRD
MMAR_2855|M.marinum_M ARKVVIVGFPGVQPLDVVGPFEVFAGASLLSEGGYDVALASIDERPVATG
MUL_2902|M.ulcerans_Agy99 ARKVVTVGFPGVQPLDVVGPFEVFAGASLLSEGGYDVALASIDERPVATG
MAB_2899c|M.abscessus_ATCC_199 PHSVVVLALPGTIGFDLATAVEVFR-RVYLADGSRPYLVRVCGTEPVVSA
Mb3863|M.bovis_AF2122/97 -----------------------------MSENSHHRLATTSLTLPPG--
Rv3833|M.tuberculosis_H37Rv -----------------------------MSENSHHRLATTSLTLPPG--
MAV_0193|M.avium_104 -----------------------------MSEIGQHGLATSAQTLPPG--
Mvan_3612|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5242|M.gilvum_PYR-GCK PQAVLSKVITGAGSWGVRKPRYGDPAFCLMLEGSCVLDADGLDSIALSQG
MSMEG_4655|M.smegmatis_MC2_155 LLTEICERIDRHARGDMHTRIDGLLLSKAAGSSRPDYTVTEPLLVVMARG
TH_4270|M.thermoresistible__bu QIRAAVADIFCPHGLDVRKGSGLDASVRAQAAGSIKLVWVTYGAPVRIDV
MMAR_2855|M.marinum_M IGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVALMDWVKAAAGTARR
MUL_2902|M.ulcerans_Agy99 IGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVALMDWVKAAAGTARR
MAB_2899c|M.abscessus_ATCC_199 GPFGIATDLGLEAVSEAETIVVPARDNPTAPLP-EGVLDALRGAYERGTR
Mb3863|M.bovis_AF2122/97 -------ARIERHRHPSHQIVYPSAG-------------AVSVTTHAGTW
Rv3833|M.tuberculosis_H37Rv -------ARIERHRHPSHQIVYPSAG-------------AVSVTTHAGTW
MAV_0193|M.avium_104 -------ARIARHRHPLHQIVYPSTG-------------AVSVTTPAGTW
Mvan_3612|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5242|M.gilvum_PYR-GCK -------DFLLLPETPEFTLSAGPEATPS--------FSALDHSPHTRHG
MSMEG_4655|M.smegmatis_MC2_155 GKRIMVGDEVYEYRTGEMLIVTASLP--------------VTGHYLETDQ
TH_4270|M.thermoresistible__bu PPPSEPFHLVQIPLQGYLSVTSGDEEVVSDSALASMPDPRLPCTMRWEAH
MMAR_2855|M.marinum_M VVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPDPIFIRS
MUL_2902|M.ulcerans_Agy99 VVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPDPIFIRS
MAB_2899c|M.abscessus_ATCC_199 IASICAGAFTLAEAGILDGKRATTHWLAADLFRERYPAVHLDADVLYVDE
Mb3863|M.bovis_AF2122/97 ITPVNRAIWIPAGCWHQHKFHGHTQFHGVALDPQRYRGGPATPTVLAVNP
Rv3833|M.tuberculosis_H37Rv ITPVNRAIWIPAGCWHQHKFHGHTQFHGVALDPQRYRGGPATPTVLAVNP
MAV_0193|M.avium_104 ITPANRAIWIPAGCWHEHKFHGHTNFHGVALDPARYRRGPAAPAVLAVTP
Mvan_3612|M.vanbaalenii_PYR-1 --------MLPPARYLMR---------AKDLVDARYSEPITVDDLAAAAG
Mflv_5242|M.gilvum_PYR-GCK DASAPVTMRMLGGYFRFDPANAALLVALLPPVIHVRGGDPDAPRLTRLVE
MSMEG_4655|M.smegmatis_MC2_155 PSLGMGLELRPAALAELALRAPARPALRTGSAGSAIAVGNADAEMLDAAA
TH_4270|M.thermoresistible__bu CSEVIVRIDDDVLHRHLESLLGHPVKAPLHFSLGMPLDSGPGSSWRAAID
MMAR_2855|M.marinum_M SPKVWTAAGVTAGIDLALALVEGDHGTEIAQTVARWLVLYLRRPGGQTQF
MUL_2902|M.ulcerans_Agy99 SPKVWTAAGVTAGIDLALALVEGDHGTEIAQTVARWLVLYLRRPCGQTQF
MAB_2899c|M.abscessus_ATCC_199 G-QVLTSAGAAAGLDLCLHIVARDHGAAVAAEAARVAVAPLHRDGGQAQY
Mb3863|M.bovis_AF2122/97 LMRELIIACSQA--------------DRTDTDEHHRMLAVLQDQLPTTSI
Rv3833|M.tuberculosis_H37Rv LMRELVIACSQA--------------DRTDTDEHHRMLAVLQDQLPTTSI
MAV_0193|M.avium_104 LMRELIIACSRA--------------RDTDAGAHHRMLAVLHDQLQATSV
Mvan_3612|M.vanbaalenii_PYR-1 LSRAHFSR-------------------MFSKTFGESPRAYLQTR----RL
Mflv_5242|M.gilvum_PYR-GCK LIAEEADADGACR-------------DAILQRLVEVLLIEAARVQSAPDL
MSMEG_4655|M.smegmatis_MC2_155 RLLRLLDRPDDAP---------------VLAPLVEQEILWRLLTGPHGDT
TH_4270|M.thermoresistible__bu MMITELDRDGGLLK------------FPLVSAQLESLILTGLLTAQPHNY
.
MMAR_2855|M.marinum_M AAPVW--MPRAKRPSIRDVQEAIEAQPGGPHSIEELAHRAAMSPRHFTRV
MUL_2902|M.ulcerans_Agy99 AAPVW--MPRAKRPSIRDVQEAIEAQPGGPHSIEELAHRAAMSPRHFTRV
MAB_2899c|M.abscessus_ATCC_199 VIRN----RRRAEVSLGEILAWIEHNAHRELSLEDLATEASTSVRSLNRR
Mb3863|M.bovis_AF2122/97 REPLW--VPSPTDRRLRHACALIADNLTQPLTLQQIGGRIGVSQRTLSRL
Rv3833|M.tuberculosis_H37Rv REPLW--VPSPTDRRLRHACALIADNLTQPLTLQQIGGRIGVSQRTLSRL
MAV_0193|M.avium_104 AEPLW--IPTAVDGRLRAACALIADNLREPLTLRQIGERIGVGQRTLSRL
Mvan_3612|M.vanbaalenii_PYR-1 ERAAS--LLRHTDRSVADICVMVGLQSVG----------------SFTTS
Mflv_5242|M.gilvum_PYR-GCK AGPHRGLITGLADPVLAPALRALHADIAHGWTVEGLARTASVSRAVFAQK
MSMEG_4655|M.smegmatis_MC2_155 VRQIA--LADSALTYINRAITWMRDNYASPVRIEDLARMAGMSTSVFHRH
TH_4270|M.thermoresistible__bu TTALLADSGPAPPRAIRRALDYIESESDRAITTARLAAHVGISARALQRG
: : : :
MMAR_2855|M.marinum_M FTGEVGEAPRQYVERVRTEAARRQLEETED----TVVAIAARCGFGTAET
MUL_2902|M.ulcerans_Agy99 FTGEVGEAPGRYVERVRTEAARRQLEETED----TVVAIAARCGFGTAET
MAB_2899c|M.abscessus_ATCC_199 FRAETGQTPMQWLTGVRVRHAQQLLERSAD----SVEWIGREVGFGSPAN
Mb3863|M.bovis_AF2122/97 FSDELGMTFPQWRTQLRLQHALVLLAERHD-----VTSVASECGWATPSA
Rv3833|M.tuberculosis_H37Rv FSDELGMTFPQWRTQLRLQHALVLLAERHD-----VTSVASECGWATPSA
MAV_0193|M.avium_104 FRDELAMTFPQWRTQVRLQHALVLLAERRD-----VTSVAAECGWATPSA
Mvan_3612|M.vanbaalenii_PYR-1 FARTYGMPPAAYRASMPPAAVHARIP---------SCILQRDT---RPKA
Mflv_5242|M.gilvum_PYR-GCK FTRAMGLTPMQYLLEWRVAVAKDLMRSERL----SIAQLAQRVGYQSATA
MSMEG_4655|M.smegmatis_MC2_155 FRAVTAMSPLQFQKRIRLQQARSLLVSQPG----DVAAVAHLVGYDSASQ
TH_4270|M.thermoresistible__bu FQEHVGCSPMDYLRDVRLRRARDLLSEADPSAEVTVTEVALECGFMHLGR
* . . : . : :
MMAR_2855|M.marinum_M MRRNFIRRVGISPDQYRKAFA--------------
MUL_2902|M.ulcerans_Agy99 MRRNFIRRVGISPDQYRKAFA--------------
MAB_2899c|M.abscessus_ATCC_199 FREQFRRLTGVSPLAYRNTFRAQSA----------
Mb3863|M.bovis_AF2122/97 FIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
Rv3833|M.tuberculosis_H37Rv FIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
MAV_0193|M.avium_104 FIDTYRRAFGHTPGRLAP-----RPS---------
Mvan_3612|M.vanbaalenii_PYR-1 DTRVDKTAHGEKTG---------------------
Mflv_5242|M.gilvum_PYR-GCK FTTAFTRVAGAPPTEFARTLAPGGV----------
MSMEG_4655|M.smegmatis_MC2_155 FTREYRRMFGAPPGQDAARLRAAHAPEPALLP---
TH_4270|M.thermoresistible__bu FSVEYRRRFGESPSETLRR----------------
* .