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SEIGQHGLATSAQTLPPGARIARHRHPLHQIVYPSTGAVSVTTPAGTWITPANRAIWIPAGCWHEHKFHG HTNFHGVALDPARYRRGPAAPAVLAVTPLMRELIIACSRARDTDAGAHHRMLAVLHDQLQATSVAEPLWI PTAVDGRLRAACALIADNLREPLTLRQIGERIGVGQRTLSRLFRDELAMTFPQWRTQVRLQHALVLLAER RDVTSVAAECGWATPSAFIDTYRRAFGHTPGRLAPRPS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0193 | - | - | 100% (249) | transcriptional regulator, AraC family protein |
| M. avium 104 | MAV_0221 | - | 1e-05 | 26.57% (143) | transcriptional regulator, AraC family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3863 | - | 1e-115 | 80.00% (245) | AraC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2370 | - | 2e-20 | 29.36% (235) | AraC family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3833 | - | 1e-115 | 79.59% (245) | AraC family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1337c | - | 1e-68 | 54.04% (235) | AraC family transcriptional regulator |
| M. marinum M | MMAR_2855 | - | 5e-06 | 27.27% (110) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_4601 | - | 6e-24 | 30.60% (232) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_2340 | - | 6e-19 | 28.88% (232) | transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_2902 | - | 1e-05 | 26.36% (110) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4276 | - | 6e-21 | 30.34% (234) | AraC family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2370|M.gilvum_PYR-GCK ---------------------------------MTVSASSDRVLSETANL
Mvan_4276|M.vanbaalenii_PYR-1 ---------------------------------MTVSASSDRILSEAANL
TH_2340|M.thermoresistible__bu ---------------------------------VTVSALSARNLASSAKP
Mb3863|M.bovis_AF2122/97 --------------------------------------------------
Rv3833|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0193|M.avium_104 --------------------------------------------------
MAB_1337c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_2855|M.marinum_M MARKVVIVGFPGVQPLDVVGPFEVFAGASLLSEGGYDVALASIDERPVAT
MUL_2902|M.ulcerans_Agy99 MARKVVTVGFPGVQPLDVVGPFEVFAGASLLSEGGYDVALASIDERPVAT
MSMEG_4601|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2370|M.gilvum_PYR-GCK ---SPRRVIDLRRGGRALGGSYLYEGDELITGWHSHDVHQIEYALHGVVE
Mvan_4276|M.vanbaalenii_PYR-1 GAGPPRRVIDLRRGGRALGGSYLYEGDALITGWHSHDVHQIEYALHGVVE
TH_2340|M.thermoresistible__bu ------PQIDLRRGGRALGGSYLYEGDKLQTGWHSHDVHQIEYAIGGVVE
Mb3863|M.bovis_AF2122/97 -------MSENSHHRLATTSLTLPPGARIER--HRHPSHQIVYPSAGAVS
Rv3833|M.tuberculosis_H37Rv -------MSENSHHRLATTSLTLPPGARIER--HRHPSHQIVYPSAGAVS
MAV_0193|M.avium_104 -------MSEIGQHGLATSAQTLPPGARIAR--HRHPLHQIVYPSTGAVS
MAB_1337c|M.abscessus_ATCC_199 -------MLIN---RHLTGVMSVAGGHRINR--HWHQEHQIVYPASGVLA
MMAR_2855|M.marinum_M GIGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVALMDWVKAAAGTAR
MUL_2902|M.ulcerans_Agy99 GIGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVALMDWVKAAAGTAR
MSMEG_4601|M.smegmatis_MC2_155 -MRTTVETHDNLARDVLALATDYSYGEVLAP--HRHRRAQFLYGVGGTMD
* : . : *.
Mflv_2370|M.gilvum_PYR-GCK --VETDSAHYLLPPQ---QAAWIPAGLEHQAVMNPDVKTVAVMFDPALIA
Mvan_4276|M.vanbaalenii_PYR-1 --VETDSAHYLLPPQ---QAAWIPAGLEHQAVMNPDVKTVAVMFDPTLIP
TH_2340|M.thermoresistible__bu --VQTRTGHYLLPPQ---QAAWLPVGLEHSATMNPDVKTVAVMFDPQLVP
Mb3863|M.bovis_AF2122/97 --VTTHAGTWITPVN---RAIWIPAGCWHQHKFHGHTQFHGVALDPQRYR
Rv3833|M.tuberculosis_H37Rv --VTTHAGTWITPVN---RAIWIPAGCWHQHKFHGHTQFHGVALDPQRYR
MAV_0193|M.avium_104 --VTTPAGTWITPAN---RAIWIPAGCWHEHKFHGHTNFHGVALDPARYR
MAB_1337c|M.abscessus_ATCC_199 --VTTDEGTWIAPPN---RALWIPSGAGHEHRFYGPTQFHSVAFDPGVYP
MMAR_2855|M.marinum_M RVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPDPIFIR
MUL_2902|M.ulcerans_Agy99 RVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPDPIFIR
MSMEG_4601|M.smegmatis_MC2_155 --VRTEHGSWLVPTE---RAVLIPPQTQHAVTMWG-VSTRSLYIEPGAVP
* . . :: . . . . : : :*
Mflv_2370|M.gilvum_PYR-GCK DGGDRARILAVSPLIREMMIYALRWPIDRGPADAASDDTVADGFFRTMAA
Mvan_4276|M.vanbaalenii_PYR-1 DGGDRARILAVSPLIREMMIYALRWHIERGPG-AGDDDGVADGFFRTLAA
TH_2340|M.thermoresistible__bu DAGNRARILAVSPLIREMMIYALRWPIDRPHG-----DEISDTFFRTLAH
Mb3863|M.bovis_AF2122/97 GGPATPTVLAVNPLMRELIIACSQADRTDTDE--------HHRMLAVLQD
Rv3833|M.tuberculosis_H37Rv GGPATPTVLAVNPLMRELVIACSQADRTDTDE--------HHRMLAVLQD
MAV_0193|M.avium_104 RGPAAPAVLAVTPLMRELIIACSRARDTDAGA--------HHRMLAVLHD
MAB_1337c|M.abscessus_ATCC_199 VELASPTVIAVSPLLRELIITCSDPGDLPEEE--------VARLRVVLID
MMAR_2855|M.marinum_M SSPKVWTAAGVTAGIDLALALVEGDHGTEIAQ------TVARWLVLYLRR
MUL_2902|M.ulcerans_Agy99 SSPKVWTAAGVTAGIDLALALVEGDHGTEIAQ------TVARWLVLYLRR
MSMEG_4601|M.smegmatis_MC2_155 WFPTRCTVVDVPTLLRELLVAAVAVPLDRPPD-------ARDAALFALTL
* . : : :
Mflv_2370|M.gilvum_PYR-GCK LVCEALDHEAPLSLPTSDHPIVAAALDYTKRHLDTATAEEVSRAVSVSER
Mvan_4276|M.vanbaalenii_PYR-1 LVCEALDHEAPLSLPTSDNPIVAAAMAYTKQHLDTVTCEEVSRAVSVSER
TH_2340|M.thermoresistible__bu LVSEALDHEAPLSLPTSDHPIVAAAMAYTKEHLQSVTAEEVSRAVAVSER
Mb3863|M.bovis_AF2122/97 QLPTTSIREPLWVPSPTDRRLRHACALIADNLTQPLTLQQIGGRIGVSQR
Rv3833|M.tuberculosis_H37Rv QLPTTSIREPLWVPSPTDRRLRHACALIADNLTQPLTLQQIGGRIGVSQR
MAV_0193|M.avium_104 QLQATSVAEPLWIPTAVDGRLRAACALIADNLREPLTLRQIGERIGVGQR
MAB_1337c|M.abscessus_ATCC_199 QLR-HSPEQALRLPTPHDERLAEACALVEEDLTQVWTVADLGRRVGASER
MMAR_2855|M.marinum_M PGGQTQFAAPVWMPRAKRPSIRDVQEAIEAQPGGPHSIEELAHRAAMSPR
MUL_2902|M.ulcerans_Agy99 PCGQTQFAAPVWMPRAKRPSIRDVQEAIEAQPGGPHSIEELAHRAAMSPR
MSMEG_4601|M.smegmatis_MC2_155 HEVAGCTSLPLDLPLPQPGALSEQCRRFLAAPRIDTTTGWWANALHVSER
. . : : . . *
Mflv_2370|M.gilvum_PYR-GCK TLRRLFADTLGLPWRTYLLHARMLRAMAPLAAPAQSVQETATAVGFDSVS
Mvan_4276|M.vanbaalenii_PYR-1 TLRRLFAETLGLPWRTYLLHARMLRAMALLTAPTQSVQGTATAVGFDSVS
TH_2340|M.thermoresistible__bu TLRRQFRQATGISWRTYLLHARMLKAMALLAAPDQSVQETASAVGFDSLS
Mb3863|M.bovis_AF2122/97 TLSRLFSDELGMTFPQWRTQLRLQHALVLLAE-RHDVTSVASECGWATPS
Rv3833|M.tuberculosis_H37Rv TLSRLFSDELGMTFPQWRTQLRLQHALVLLAE-RHDVTSVASECGWATPS
MAV_0193|M.avium_104 TLSRLFRDELAMTFPQWRTQVRLQHALVLLAE-RRDVTSVAAECGWATPS
MAB_1337c|M.abscessus_ATCC_199 TLTRLFRTDMGMTYPQWRTQIRLHHALRLLAE-DRPVTYVAHQCGWATPS
MMAR_2855|M.marinum_M HFTRVFTGEVGEAPRQYVERVRTEAARRQLEETEDTVVAIAARCGFGTAE
MUL_2902|M.ulcerans_Agy99 HFTRVFTGEVGEAPGRYVERVRTEAARRQLEETEDTVVAIAARCGFGTAE
MSMEG_4601|M.smegmatis_MC2_155 TVARLFRKELSMTVAEWQRRACVLHSLRQLTQ-GVAVSAVASDLGYSSPA
. * * . . : : : * * * *: :
Mflv_2370|M.gilvum_PYR-GCK SFTRAFAQFCGETPSAYRKRVADSD-----------
Mvan_4276|M.vanbaalenii_PYR-1 SFTRAFTQFCGETPSAYRKRVADASD----------
TH_2340|M.thermoresistible__bu AFTRAFTQFCGETPSAYRHRISTDPHSRPTSADPIG
Mb3863|M.bovis_AF2122/97 AFIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
Rv3833|M.tuberculosis_H37Rv AFIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
MAV_0193|M.avium_104 AFIDTYRRAFGHTPGRLAP-----RPS---------
MAB_1337c|M.abscessus_ATCC_199 AFIDVYRRTLGQTPGTYAAP-----VTR--------
MMAR_2855|M.marinum_M TMRRNFIRRVGISPDQYRKAFA--------------
MUL_2902|M.ulcerans_Agy99 TMRRNFIRRVGISPDQYRKAFA--------------
MSMEG_4601|M.smegmatis_MC2_155 AFSTMFSRALGTSPSAFSPRRLNL------------
:: : : * :*.