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MSENSHHRLATTSLTLPPGARIERHRHPSHQIVYPSAGAVSVTTHAGTWITPVNRAIWIPAGCWHQHKFH GHTQFHGVALDPQRYRGGPATPTVLAVNPLMRELIIACSQADRTDTDEHHRMLAVLQDQLPTTSIREPLW VPSPTDRRLRHACALIADNLTQPLTLQQIGGRIGVSQRTLSRLFSDELGMTFPQWRTQLRLQHALVLLAE RHDVTSVASECGWATPSAFIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3863 | - | - | 100% (263) | AraC family transcriptional regulator |
| M. bovis AF2122 / 97 | Mb1966c | - | 2e-05 | 30.12% (83) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2370 | - | 2e-20 | 29.54% (237) | AraC family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3833 | - | 1e-156 | 99.62% (263) | AraC family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1337c | - | 1e-71 | 54.13% (242) | AraC family transcriptional regulator |
| M. marinum M | MMAR_2855 | - | 2e-06 | 25.42% (118) | transcriptional regulatory protein |
| M. avium 104 | MAV_0193 | - | 1e-115 | 80.00% (245) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_6546 | - | 1e-23 | 32.59% (224) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_2340 | - | 8e-20 | 30.80% (224) | transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_2902 | - | 4e-06 | 24.58% (118) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4276 | - | 5e-20 | 29.66% (236) | AraC family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3863|M.bovis_AF2122/97 --------------------------------------------------
Rv3833|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0193|M.avium_104 --------------------------------------------------
MAB_1337c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2370|M.gilvum_PYR-GCK ---------------------------------MTVSASSDRVLSETANL
Mvan_4276|M.vanbaalenii_PYR-1 ---------------------------------MTVSASSDRILSEAANL
MSMEG_6546|M.smegmatis_MC2_155 -------------------------------------------MTETANL
TH_2340|M.thermoresistible__bu ---------------------------------VTVSALSARNLASSAKP
MMAR_2855|M.marinum_M MARKVVIVGFPGVQPLDVVGPFEVFAGASLLSEGGYDVALASIDERPVAT
MUL_2902|M.ulcerans_Agy99 MARKVVTVGFPGVQPLDVVGPFEVFAGASLLSEGGYDVALASIDERPVAT
Mb3863|M.bovis_AF2122/97 -------MSENSHHRLATTSLTLPPGARIER--HRHPSHQIVYPSAGAVS
Rv3833|M.tuberculosis_H37Rv -------MSENSHHRLATTSLTLPPGARIER--HRHPSHQIVYPSAGAVS
MAV_0193|M.avium_104 -------MSEIGQHGLATSAQTLPPGARIAR--HRHPLHQIVYPSTGAVS
MAB_1337c|M.abscessus_ATCC_199 -------MLIN---RHLTGVMSVAGGHRINR--HWHQEHQIVYPASGVLA
Mflv_2370|M.gilvum_PYR-GCK ---SPRRVIDLRRGGRALGGSYLYEGDELITGWHSHDVHQIEYALHGVVE
Mvan_4276|M.vanbaalenii_PYR-1 GAGPPRRVIDLRRGGRALGGSYLYEGDALITGWHSHDVHQIEYALHGVVE
MSMEG_6546|M.smegmatis_MC2_155 ----TRPVIELRRGGRALAGSYLYEGEGLITGWHSHEVHQIEYALHGVVE
TH_2340|M.thermoresistible__bu ------PQIDLRRGGRALGGSYLYEGDKLQTGWHSHDVHQIEYAIGGVVE
MMAR_2855|M.marinum_M GIGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVALMDWVKAAAGTAR
MUL_2902|M.ulcerans_Agy99 GIGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVALMDWVKAAAGTAR
: * : . : . *.
Mb3863|M.bovis_AF2122/97 --VTTHAGTWITPVN---RAIWIPAGCWHQHKFHGHTQFHGVALDPQRYR
Rv3833|M.tuberculosis_H37Rv --VTTHAGTWITPVN---RAIWIPAGCWHQHKFHGHTQFHGVALDPQRYR
MAV_0193|M.avium_104 --VTTPAGTWITPAN---RAIWIPAGCWHEHKFHGHTNFHGVALDPARYR
MAB_1337c|M.abscessus_ATCC_199 --VTTDEGTWIAPPN---RALWIPSGAGHEHRFYGPTQFHSVAFDPGVYP
Mflv_2370|M.gilvum_PYR-GCK --VETDSAHYLLPPQ---QAAWIPAGLEHQAVMNPDVKTVAVMFDPALIA
Mvan_4276|M.vanbaalenii_PYR-1 --VETDSAHYLLPPQ---QAAWIPAGLEHQAVMNPDVKTVAVMFDPTLIP
MSMEG_6546|M.smegmatis_MC2_155 --VETDAAHYLLPPQ---QAAWIPAGLQHQAVMNPDVKTVAVMFDPQMIP
TH_2340|M.thermoresistible__bu --VQTRTGHYLLPPQ---QAAWLPVGLEHSATMNPDVKTVAVMFDPQLVP
MMAR_2855|M.marinum_M RVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPDPIFIR
MUL_2902|M.ulcerans_Agy99 RVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPDPIFIR
* . . :: . . . . : * **
Mb3863|M.bovis_AF2122/97 GGPATPTVLAVNPLMRELIIACSQADRTDTDE--------HHRMLAVLQD
Rv3833|M.tuberculosis_H37Rv GGPATPTVLAVNPLMRELVIACSQADRTDTDE--------HHRMLAVLQD
MAV_0193|M.avium_104 RGPAAPAVLAVTPLMRELIIACSRARDTDAGA--------HHRMLAVLHD
MAB_1337c|M.abscessus_ATCC_199 VELASPTVIAVSPLLRELIITCSDPGDLPEEE--------VARLRVVLID
Mflv_2370|M.gilvum_PYR-GCK DGGDRARILAVSPLIREMMIYALRWPIDRGPADAASDDTVADGFFRTMAA
Mvan_4276|M.vanbaalenii_PYR-1 DGGDRARILAVSPLIREMMIYALRWHIERGPG-AGDDDGVADGFFRTLAA
MSMEG_6546|M.smegmatis_MC2_155 DGGTRARIIAVSPLIREMMIYGLRWPIDRADG-----DEISDGFFQTLAN
TH_2340|M.thermoresistible__bu DAGNRARILAVSPLIREMMIYALRWPIDRPHG-----DEISDTFFRTLAH
MMAR_2855|M.marinum_M SSPKVWTAAGVTAGIDLALALVEGDHGTEIAQ------TVARWLVLYLRR
MUL_2902|M.ulcerans_Agy99 SSPKVWTAAGVTAGIDLALALVEGDHGTEIAQ------TVARWLVLYLRR
.*.. : : : :
Mb3863|M.bovis_AF2122/97 QLPTTSIREPLWVPSPTDRRLRHACALIADNLTQPLTLQQIGGRIGVSQR
Rv3833|M.tuberculosis_H37Rv QLPTTSIREPLWVPSPTDRRLRHACALIADNLTQPLTLQQIGGRIGVSQR
MAV_0193|M.avium_104 QLQATSVAEPLWIPTAVDGRLRAACALIADNLREPLTLRQIGERIGVGQR
MAB_1337c|M.abscessus_ATCC_199 QLR-HSPEQALRLPTPHDERLAEACALVEEDLTQVWTVADLGRRVGASER
Mflv_2370|M.gilvum_PYR-GCK LVCEALDHEAPLSLPTSDHPIVAAALDYTKRHLDTATAEEVSRAVSVSER
Mvan_4276|M.vanbaalenii_PYR-1 LVCEALDHEAPLSLPTSDNPIVAAAMAYTKQHLDTVTCEEVSRAVSVSER
MSMEG_6546|M.smegmatis_MC2_155 LVAEALDHEAPLSLPTSDNPIVAAALAYTKEHLDSVTAEQVSRAVSVSER
TH_2340|M.thermoresistible__bu LVSEALDHEAPLSLPTSDHPIVAAAMAYTKEHLQSVTAEEVSRAVAVSER
MMAR_2855|M.marinum_M PGGQTQFAAPVWMPRAKRPSIRDVQEAIEAQPGGPHSIEELAHRAAMSPR
MUL_2902|M.ulcerans_Agy99 PCGQTQFAAPVWMPRAKRPSIRDVQEAIEAQPGGPHSIEELAHRAAMSPR
. . : . : ::. . . *
Mb3863|M.bovis_AF2122/97 TLSRLFSDELGMTFPQWRTQLRLQHALVLLAE-RHDVTSVASECGWATPS
Rv3833|M.tuberculosis_H37Rv TLSRLFSDELGMTFPQWRTQLRLQHALVLLAE-RHDVTSVASECGWATPS
MAV_0193|M.avium_104 TLSRLFRDELAMTFPQWRTQVRLQHALVLLAE-RRDVTSVAAECGWATPS
MAB_1337c|M.abscessus_ATCC_199 TLTRLFRTDMGMTYPQWRTQIRLHHALRLLAE-DRPVTYVAHQCGWATPS
Mflv_2370|M.gilvum_PYR-GCK TLRRLFADTLGLPWRTYLLHARMLRAMAPLAAPAQSVQETATAVGFDSVS
Mvan_4276|M.vanbaalenii_PYR-1 TLRRLFAETLGLPWRTYLLHARMLRAMALLTAPTQSVQGTATAVGFDSVS
MSMEG_6546|M.smegmatis_MC2_155 TLRRLFADTIGMSWRTYLLHARMLRAMALLADQDQSVQATATAVGFENLS
TH_2340|M.thermoresistible__bu TLRRQFRQATGISWRTYLLHARMLKAMALLAAPDQSVQETASAVGFDSLS
MMAR_2855|M.marinum_M HFTRVFTGEVGEAPRQYVERVRTEAARRQLEETEDTVVAIAARCGFGTAE
MUL_2902|M.ulcerans_Agy99 HFTRVFTGEVGEAPGRYVERVRTEAARRQLEETEDTVVAIAARCGFGTAE
: * * . . : : * * * * * *: . .
Mb3863|M.bovis_AF2122/97 AFIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
Rv3833|M.tuberculosis_H37Rv AFIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
MAV_0193|M.avium_104 AFIDTYRRAFGHTPGRLAP-----RPS---------
MAB_1337c|M.abscessus_ATCC_199 AFIDVYRRTLGQTPGTYAAP-----VTR--------
Mflv_2370|M.gilvum_PYR-GCK SFTRAFAQFCGETPSAYRKRVADSD-----------
Mvan_4276|M.vanbaalenii_PYR-1 SFTRAFTQFCGETPSAYRKRVADASD----------
MSMEG_6546|M.smegmatis_MC2_155 SFTRCFAQFCGETPSNYRRRATGS------------
TH_2340|M.thermoresistible__bu AFTRAFTQFCGETPSAYRHRISTDPHSRPTSADPIG
MMAR_2855|M.marinum_M TMRRNFIRRVGISPDQYRKAFA--------------
MUL_2902|M.ulcerans_Agy99 TMRRNFIRRVGISPDQYRKAFA--------------
:: : : * :*.