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MRRVAVLAVPDVVAFDLSIPIEVFGRVRLADGMNGYRVQVCGTEPTVSAGPLRIATDHGLEALADADTII VPGRENLPTQTPAPVVTALRDAYASGATIASICTGAFVLADTGLLDGRRATTHWAAADLFRANFPAVDLD PDVLYVDAGRILTSAGASAGVDLCLHMVQRDHGAAAAANAAKMAVAPLHRSGGQAQFIIRNQPPASVIGE KTHLSEVLVWIEQNAHRELTLSDIADHAATSIRTLNRRFQAETGQTPMQWVTGVRIRHAQELLERTSLSV ERIGRDVGFTSAANFREQFRRLSGVAPQVYRNTFRERTQDIPHTTSTALASA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6839 | - | - | 100% (332) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_5193 | - | 3e-64 | 43.44% (320) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_5563 | - | 6e-64 | 42.20% (327) | AraC-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0053 | - | 8e-12 | 34.71% (121) | hypothetical protein Mb0053 |
| M. gilvum PYR-GCK | Mflv_1437 | - | 3e-60 | 38.53% (327) | AraC family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0052 | - | 8e-12 | 34.71% (121) | hypothetical protein Rv0052 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2899c | - | 1e-117 | 65.71% (315) | AraC family transcriptional regulator |
| M. marinum M | MMAR_2855 | - | 6e-43 | 33.96% (318) | transcriptional regulatory protein |
| M. avium 104 | MAV_4981 | - | 9e-45 | 35.22% (318) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_3120 | - | 1e-55 | 39.12% (317) | PUTATIVE transcriptional regulator, AraC family with |
| M. ulcerans Agy99 | MUL_2902 | - | 5e-41 | 33.33% (318) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5349 | - | 3e-59 | 39.88% (331) | AraC family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6839|M.smegmatis_MC2_155 MR------------------------------------------------
MAB_2899c|M.abscessus_ATCC_199 MRSARGPHSGEPGRSGEPHSGRLGRSGEPHSGRLGRSGEPHSGRLGRSGE
Mflv_1437|M.gilvum_PYR-GCK ------------------------------------------------MA
Mvan_5349|M.vanbaalenii_PYR-1 ------------------------------------------------MA
TH_3120|M.thermoresistible__bu --------------------------------------------------
MMAR_2855|M.marinum_M -------------------------------------------------M
MUL_2902|M.ulcerans_Agy99 -------------------------------------------------M
MAV_4981|M.avium_104 -------------------------------------------MADSSAT
Mb0053|M.bovis_AF2122/97 --------------------------------------------------
Rv0052|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_6839|M.smegmatis_MC2_155 --RVAVLAVPDVVAFDLSIPIEVFGRVRLADGMNGYRVQVCG---TEPTV
MAB_2899c|M.abscessus_ATCC_199 PHSVVVLALPGTIGFDLATAVEVFRRVYLADGSRPYLVRVCG---TEPVV
Mflv_1437|M.gilvum_PYR-GCK IKAVSTLVLDGLAVFEFGVVCEVFGIDRSADGVPNFDFKVCGPEPGEPLR
Mvan_5349|M.vanbaalenii_PYR-1 IRSVSALVLDNLAMFEFGVICEVFGIDRSADGVPNFDFKVCGPEAGSPLR
TH_3120|M.thermoresistible__bu ---VAALVLDGLAIFEFGVICEVFGVDRTDDGVPPVDFTVCGPRAGQPVR
MMAR_2855|M.marinum_M ARKVVIVGFPGVQPLDVVGPFEVFAGASLLSE-GGYDVALASID-ERPVA
MUL_2902|M.ulcerans_Agy99 ARKVVTVGFPGVQPLDVVGPFEVFAGASLLSE-GGYDVALASID-ERPVA
MAV_4981|M.avium_104 PRVVVIVVFDDVTMLDVAGAGEVFAEANRFG--ADYLLKIASVD-GRDVT
Mb0053|M.bovis_AF2122/97 --------------------------------MPSFDVVFVGHRRGEVRS
Rv0052|M.tuberculosis_H37Rv --------------------------------MPSFDVVFVGHRRGEVRS
. . .
MSMEG_6839|M.smegmatis_MC2_155 SAGPLRIATDHGLEALADADTIIVPGRENLPT-QTPAPVVTALRDAYASG
MAB_2899c|M.abscessus_ATCC_199 SAGPFGIATDLGLEAVSEAETIVVPARDNPTA-PLPEGVLDALRGAYERG
Mflv_1437|M.gilvum_PYR-GCK TSVGATITPDHGLDDLVGADLVAIPAIASRQG-TYLPEALDAIRRAAESG
Mvan_5349|M.vanbaalenii_PYR-1 TSVGATIIPDHGLDHLVGADLVAIPAIGGSD---YLPEALDAVRRAAESG
TH_3120|M.thermoresistible__bu TSFGATLTPDSGLDGLAGADLVAIPAIRQDD---YLPEALDAVRAAADAG
MMAR_2855|M.marinum_M TGIGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVALMDWVKAAAGTA
MUL_2902|M.ulcerans_Agy99 TGIGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVALMDWVKAAAGTA
MAV_4981|M.avium_104 TSIGTRLGVTDAVSSIESADTVLVAGSDNLPRRPIDPELVEAVKSVADRT
Mb0053|M.bovis_AF2122/97 DNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDWVREAHRHT
Rv0052|M.tuberculosis_H37Rv DNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDWVREAHRHT
: . : : ... : :: .
MSMEG_6839|M.smegmatis_MC2_155 ATIASICTGAFVLADTGLLDGRRATTHWAAADLFRANFPAVDLDPDVLYV
MAB_2899c|M.abscessus_ATCC_199 TRIASICAGAFTLAEAGILDGKRATTHWLAADLFRERYPAVHLDADVLYV
Mflv_1437|M.gilvum_PYR-GCK SIILTVCSGAFVAGAAGLLDGRPCTTHWMHADALAEMYPTAKVDRNVLFV
Mvan_5349|M.vanbaalenii_PYR-1 SIILTVCSGAFVAGAAGLLDGRPCTTHWMHADELARMYPTAKVDRNVLFV
TH_3120|M.thermoresistible__bu AIILTVCSGAFLAGAAGLLDGRPCTTHWGLTEELARRYPTARVDRNVLYV
MMAR_2855|M.marinum_M RRVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPDPIFI
MUL_2902|M.ulcerans_Agy99 RRVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPDPIFI
MAV_4981|M.avium_104 RRLASICTGSFILGQAGLLDGRRATTHWHDVRLFARAFPEITVEPDALFV
Mb0053|M.bovis_AF2122/97 LLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHL
Rv0052|M.tuberculosis_H37Rv LLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHL
::*:* : . :*:*:* .**** : . : .:
MSMEG_6839|M.smegmatis_MC2_155 DAG-RILTSAGASAGVDLCLHMVQRDHGAAAAANAAKMAVAPLHRSGGQA
MAB_2899c|M.abscessus_ATCC_199 DEG-QVLTSAGAAAGLDLCLHIVARDHGAAVAAEAARVAVAPLHRDGGQA
Mflv_1437|M.gilvum_PYR-GCK DDG-NLITSAGTAAGIDACLHLVRREMGSEVTNKIARRMVVPPQRDGGQR
Mvan_5349|M.vanbaalenii_PYR-1 DDG-NLITSAGTAAGIDACLHLVRRELGSEVTNKIARRMVVPPQRDGGQR
TH_3120|M.thermoresistible__bu DDG-DLITSAGTAAGIDACLHLVRRELGSEVTNTIARHMVVPPQRDGGQR
MMAR_2855|M.marinum_M RSSPKVWTAAGVTAGIDLALALVEGDHGTEIAQTVARWLVLYLRRPGGQT
MUL_2902|M.ulcerans_Agy99 RSSPKVWTAAGVTAGIDLALALVEGDHGTEIAQTVARWLVLYLRRPCGQT
MAV_4981|M.avium_104 CDG-DVFTSAGISSGIDLALALVEMDYGTELVRAVARWLVVYLKRAGGQS
Mb0053|M.bovis_AF2122/97 PER--VITAAGVSSGIDMGLRLVELLVSREAAEASQ--------------
Rv0052|M.tuberculosis_H37Rv PER--VITAAGVSSGIDMGLRLVELLVSREAAEASQ--------------
: *:** ::*:* * :* . .
MSMEG_6839|M.smegmatis_MC2_155 QFIIRNQPPASVIGEKTHLSEVLVWIEQNAHRELTLSDIADHAATSIRTL
MAB_2899c|M.abscessus_ATCC_199 QYVIRNRRRAEVS-----LGEILAWIEHNAHRELSLEDLATEASTSVRSL
Mflv_1437|M.gilvum_PYR-GCK QYIDQPIPVKCSER----FAPQLDWILANLDKPHTVTSLSRRAHMSGRTF
Mvan_5349|M.vanbaalenii_PYR-1 QYIDQPIPVKCSER----FAPHLDWILANLDKPHTVTTLARRAHMSGRTF
TH_3120|M.thermoresistible__bu QFIDQPIPVRHSEG----FAPHLDWILSNLDKTHTVASLARRANMSPRTF
MMAR_2855|M.marinum_M QFAAPVWMPRAKRPS---IRDVQEAIEAQPGGPHSIEELAHRAAMSPRHF
MUL_2902|M.ulcerans_Agy99 QFAAPVWMPRAKRPS---IRDVQEAIEAQPGGPHSIEELAHRAAMSPRHF
MAV_4981|M.avium_104 QFSALVEAEPPPRSP---LRKVTAAISADPAADHSVKSLSARASLSTRQL
Mb0053|M.bovis_AF2122/97 -----------------------LMIEYDPQPPVDAGSLAKASPATHRLA
Rv0052|M.tuberculosis_H37Rv -----------------------LMIEYDPQPPVDAGSLAKASPATHRLA
* : :: : : *
MSMEG_6839|M.smegmatis_MC2_155 NRRFQAETGQTPMQWVTGVRIRHAQELLERTSLSVERIGRDVGFTSAANF
MAB_2899c|M.abscessus_ATCC_199 NRRFRAETGQTPMQWLTGVRVRHAQQLLERSADSVEWIGREVGFGSPANF
Mflv_1437|M.gilvum_PYR-GCK ARRFVEETGRTPMQWITDQRVLYARRMLEETTLDIDRIAEQSGFGTATLL
Mvan_5349|M.vanbaalenii_PYR-1 ARRFVEETGRTPMQWVTDQRVLFARRMLEETNLDIDRIAEQSGFGTATLL
TH_3120|M.thermoresistible__bu ARRFVEETGRTPMQWVTDQRVLYARRLLEETDLDIHRIAARCGFGSTTLL
MMAR_2855|M.marinum_M TRVFTGEVGEAPRQYVERVRTEAARRQLEETEDTVVAIAARCGFGTAETM
MUL_2902|M.ulcerans_Agy99 TRVFTGEVGEAPGRYVERVRTEAARRQLEETEDTVVAIAARCGFGTAETM
MAV_4981|M.avium_104 TRLFQSELGTTPARYVEMVRIDAARAALDAGR-SVAESARLAGFGSAETL
Mb0053|M.bovis_AF2122/97 LEFYQHRL------------------------------------------
Rv0052|M.tuberculosis_H37Rv LEFYQHRL------------------------------------------
. : .
MSMEG_6839|M.smegmatis_MC2_155 REQFRRLSGVAPQVYRNTFR-----ERTQDIPHTTSTALASA
MAB_2899c|M.abscessus_ATCC_199 REQFRRLTGVSPLAYRNTFR-----AQSA-------------
Mflv_1437|M.gilvum_PYR-GCK RHHFRRLIGVTPSDYRKRFN-----AHAP-EVAEIA------
Mvan_5349|M.vanbaalenii_PYR-1 RHHFRRIIGVTPSDYRRRFN-----STASQDVAVIA------
TH_3120|M.thermoresistible__bu RHHFRRVIGVTPSDYRRRFACGSTTSGSTESGAEVTD-----
MMAR_2855|M.marinum_M RRNFIRRVGISPDQYRKAFA----------------------
MUL_2902|M.ulcerans_Agy99 RRNFIRRVGISPDQYRKAFA----------------------
MAV_4981|M.avium_104 RRVFVEHLGLSPKAYRDRFRT----AARG-------------
Mb0053|M.bovis_AF2122/97 ------------------------------------------
Rv0052|M.tuberculosis_H37Rv ------------------------------------------