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RTTVETHDNLARDVLALATDYSYGEVLAPHRHRRAQFLYGVGGTMDVRTEHGSWLVPTERAVLIPPQTQH AVTMWGVSTRSLYIEPGAVPWFPTRCTVVDVPTLLRELLVAAVAVPLDRPPDARDAALFALTLHEVAGCT SLPLDLPLPQPGALSEQCRRFLAAPRIDTTTGWWANALHVSERTVARLFRKELSMTVAEWQRRACVLHSL RQLTQGVAVSAVASDLGYSSPAAFSTMFSRALGTSPSAFSPRRLNL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4601 | - | - | 100% (257) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_6546 | - | 4e-18 | 28.69% (251) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_3488 | - | 4e-07 | 30.77% (104) | transcriptional regulator, AraC family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3863 | - | 1e-20 | 29.51% (244) | AraC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2370 | - | 5e-16 | 29.39% (262) | AraC family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3833 | - | 2e-20 | 29.51% (244) | AraC family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1109c | - | 2e-59 | 48.13% (241) | AraC family transcriptional regulator |
| M. marinum M | MMAR_3156 | - | 2e-06 | 35.35% (99) | AraC/XylS family transcriptional regulator |
| M. avium 104 | MAV_0193 | - | 5e-24 | 30.60% (232) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_2340 | - | 4e-19 | 30.20% (255) | transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_0821 | - | 9e-05 | 42.62% (61) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4276 | - | 1e-17 | 29.30% (256) | AraC family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4601|M.smegmatis_MC2_155 ---------------------------MR-TTVETHDNLARDV-------
MAB_1109c|M.abscessus_ATCC_199 ---------------------------MRNIPLADVDHLPHEV-------
Mb3863|M.bovis_AF2122/97 ----------------------------------MSENSHHRL-------
Rv3833|M.tuberculosis_H37Rv ----------------------------------MSENSHHRL-------
MAV_0193|M.avium_104 ----------------------------------MSEIGQHGL-------
Mflv_2370|M.gilvum_PYR-GCK --------MTVSASSDRVLSETANL---SPRRVIDLRRGGRAL-------
Mvan_4276|M.vanbaalenii_PYR-1 --------MTVSASSDRILSEAANLGAGPPRRVIDLRRGGRAL-------
TH_2340|M.thermoresistible__bu --------VTVSALSARNLASSAKP------PQIDLRRGGRAL-------
MUL_0821|M.ulcerans_Agy99 MDYLWRMAQAARLIQHRSGVPIYGYRTDPDIPRVSVRRPGPED-------
MMAR_3156|M.marinum_M -MNPNDAGVPPLAFVQMLESPAFDPDAVARLRNIMAREGTDEATLIQRDI
MSMEG_4601|M.smegmatis_MC2_155 -----------------LALATDYSYGEVLAPHRHRRAQFLYGVGGTMDV
MAB_1109c|M.abscessus_ATCC_199 -----------------LPISTDYADGQLLDWHRHRRAQFLYATTGTMIV
Mb3863|M.bovis_AF2122/97 -----------------ATTSLTLPPGARIERHRHPSHQIVYPSAGAVSV
Rv3833|M.tuberculosis_H37Rv -----------------ATTSLTLPPGARIERHRHPSHQIVYPSAGAVSV
MAV_0193|M.avium_104 -----------------ATSAQTLPPGARIARHRHPLHQIVYPSTGAVSV
Mflv_2370|M.gilvum_PYR-GCK -----------------GGSYLYEGDELITGWHSHDVHQIEYALHGVVEV
Mvan_4276|M.vanbaalenii_PYR-1 -----------------GGSYLYEGDALITGWHSHDVHQIEYALHGVVEV
TH_2340|M.thermoresistible__bu -----------------GGSYLYEGDKLQTGWHSHDVHQIEYAIGGVVEV
MUL_0821|M.ulcerans_Agy99 -----------------LGDRARHIHDFPALWYVPAAGLVYIAAAGQVLE
MMAR_3156|M.marinum_M QAPLRWFREAYPGLDIDQATLLGFALAEQAQLTSFGPLSVPLVSAGSVAE
. * :
MSMEG_4601|M.smegmatis_MC2_155 RTEHGSWLVPTERAVLIPPQTQHAVTMWGVS-TRS-LYIEPGA-VPWFPT
MAB_1109c|M.abscessus_ATCC_199 DTDAGTWTVPTHRAVMIPARTRHRVRMFEVR-TGS-LYVEPSA-APWWPT
Mb3863|M.bovis_AF2122/97 TTHAGTWITPVNRAIWIPAGCWHQHKFHGHT-QFHGVALDPQR-YRGGPA
Rv3833|M.tuberculosis_H37Rv TTHAGTWITPVNRAIWIPAGCWHQHKFHGHT-QFHGVALDPQR-YRGGPA
MAV_0193|M.avium_104 TTPAGTWITPANRAIWIPAGCWHEHKFHGHT-NFHGVALDPAR-YRRGPA
Mflv_2370|M.gilvum_PYR-GCK ETDSAHYLLPPQQAAWIPAGLEHQAVMNPDV-KTVAVMFDPAL-IADGGD
Mvan_4276|M.vanbaalenii_PYR-1 ETDSAHYLLPPQQAAWIPAGLEHQAVMNPDV-KTVAVMFDPTL-IPDGGD
TH_2340|M.thermoresistible__bu QTRTGHYLLPPQQAAWLPVGLEHSATMNPDV-KTVAVMFDPQL-VPDAGN
MUL_0821|M.ulcerans_Agy99 PTQFGSLQAGVAMFFDPAALGGDGGSPWPSW-RTHPLLFPFLHGHSGGIL
MMAR_3156|M.marinum_M IVELLTYLPLITTAVKAQFHPDDQGLTVGLWGHTSDRALDCLAVTYAGLA
. . .
MSMEG_4601|M.smegmatis_MC2_155 RCTVVDVPTLLRELLVAAVAVPLDRPPDAR------DAALFALTLHEVAG
MAB_1109c|M.abscessus_ATCC_199 SCVVVDVSPLMHELLSAAADLDVDYDRSGR------GGALITLLLHEIAS
Mb3863|M.bovis_AF2122/97 TPTVLAVNPLMRELIIACSQADRT-DTDEH------HRMLAVLQDQLPTT
Rv3833|M.tuberculosis_H37Rv TPTVLAVNPLMRELVIACSQADRT-DTDEH------HRMLAVLQDQLPTT
MAV_0193|M.avium_104 APAVLAVTPLMRELIIACSRARDT-DAGAH------HRMLAVLHDQLQAT
Mflv_2370|M.gilvum_PYR-GCK RARILAVSPLIREMMIYALRWPIDRGPADAASDDTVADGFFRTMAALVCE
Mvan_4276|M.vanbaalenii_PYR-1 RARILAVSPLIREMMIYALRWHIERGPG-AGDDDGVADGFFRTLAALVCE
TH_2340|M.thermoresistible__bu RARILAVSPLIREMMIYALRWPIDRPHG-----DEISDTFFRTLAHLVSE
MUL_0821|M.ulcerans_Agy99 RLEVPAARRSTWDGAIAAIEAELTTRQQGYG---QAVTAHLTLLLIELAR
MMAR_3156|M.marinum_M LLRLLDMLVRAAPTLTLHLSWPAPAALKDREDDLTAGRLFFDAPMSFLHV
:
MSMEG_4601|M.smegmatis_MC2_155 --------------------CTSLPLDLPLPQ-PGALSEQCRRFLAAPRI
MAB_1109c|M.abscessus_ATCC_199 --------------------FTALPLHVDIPW-SADLAELCRTYLDAPDV
Mb3863|M.bovis_AF2122/97 --------------------SIREPLWVPSPT-DRRLRHACALIADNLTQ
Rv3833|M.tuberculosis_H37Rv --------------------SIREPLWVPSPT-DRRLRHACALIADNLTQ
MAV_0193|M.avium_104 --------------------SVAEPLWIPTAV-DGRLRAACALIADNLRE
Mflv_2370|M.gilvum_PYR-GCK --------------------ALDHEAPLSLPTSDHPIVAAALDYTKRHLD
Mvan_4276|M.vanbaalenii_PYR-1 --------------------ALDHEAPLSLPTSDNPIVAAAMAYTKQHLD
TH_2340|M.thermoresistible__bu --------------------ALDHEAPLSLPTSDHPIVAAAMAYTKEHLQ
MUL_0821|M.ulcerans_Agy99 --------------------LARDVVGDLRRSGEPLLAEVFEVIDRRHAE
MMAR_3156|M.marinum_M PADTLNEVCRFSDPVAYRLAIVDLQRTLDQRSETTSFSEKVRRLLQKEPG
:
MSMEG_4601|M.smegmatis_MC2_155 DTTTGWWANALHVSERTVARLFRKELSMTVAEWQRRACVLHSLRQLTQG-
MAB_1109c|M.abscessus_ATCC_199 SVTNAEWARRLRTSERALTRRFRDEVAMSPAAWRVRARLLAAVPLLRD--
Mb3863|M.bovis_AF2122/97 PLTLQQIGGRIGVSQRTLSRLFSDELGMTFPQWRTQLRLQHALVLLAER-
Rv3833|M.tuberculosis_H37Rv PLTLQQIGGRIGVSQRTLSRLFSDELGMTFPQWRTQLRLQHALVLLAER-
MAV_0193|M.avium_104 PLTLRQIGERIGVGQRTLSRLFRDELAMTFPQWRTQVRLQHALVLLAER-
Mflv_2370|M.gilvum_PYR-GCK TATAEEVSRAVSVSERTLRRLFADTLGLPWRTYLLHARMLRAMAPLAAPA
Mvan_4276|M.vanbaalenii_PYR-1 TVTCEEVSRAVSVSERTLRRLFAETLGLPWRTYLLHARMLRAMALLTAPT
TH_2340|M.thermoresistible__bu SVTAEEVSRAVAVSERTLRRQFRQATGISWRTYLLHARMLKAMALLAAPD
MUL_0821|M.ulcerans_Agy99 PLSLRDVAAEVGMTPGHLTTIVRRRTGRTVQEWIIERRMAQARELLVATD
MMAR_3156|M.marinum_M RRSKHWFAHELSMSTSTLKRRLSEEE-TTFRELRQAFLRERAMLQLLDRS
: . : : . . : *
MSMEG_4601|M.smegmatis_MC2_155 VAVSAVASDLGYSSPAAFSTMFSRALGTSPSAFSPRRLNL----------
MAB_1109c|M.abscessus_ATCC_199 HSVTQVAGRLGYATPAAFSYAFGRAFNIAPSSVR----------------
Mb3863|M.bovis_AF2122/97 HDVTSVASECGWATPSAFIDTYRQAFGHTPGQAAKPMAATRLTRLRRARD
Rv3833|M.tuberculosis_H37Rv HDVTSVASECGWATPSAFIDTYRQAFGHTPGQAAKPMAATRLTRLRRARD
MAV_0193|M.avium_104 RDVTSVAAECGWATPSAFIDTYRRAFGHTPGRLAP-----RPS-------
Mflv_2370|M.gilvum_PYR-GCK QSVQETATAVGFDSVSSFTRAFAQFCGETPSAYRKRVADSD---------
Mvan_4276|M.vanbaalenii_PYR-1 QSVQGTATAVGFDSVSSFTRAFTQFCGETPSAYRKRVADASD--------
TH_2340|M.thermoresistible__bu QSVQETASAVGFDSLSAFTRAFTQFCGETPSAYRHRISTDPHSRPTSADP
MUL_0821|M.ulcerans_Agy99 LAVGEVARRVGISDPGYFSRLFSRAHGTSPRQWRALPPRH----------
MMAR_3156|M.marinum_M LSVSEIATDLGYSDLANFSHAFKRWTGRSPSEFRLSPH------------
* * * . * : : . :*
MSMEG_4601|M.smegmatis_MC2_155 --
MAB_1109c|M.abscessus_ATCC_199 --
Mb3863|M.bovis_AF2122/97 RR
Rv3833|M.tuberculosis_H37Rv RR
MAV_0193|M.avium_104 --
Mflv_2370|M.gilvum_PYR-GCK --
Mvan_4276|M.vanbaalenii_PYR-1 --
TH_2340|M.thermoresistible__bu IG
MUL_0821|M.ulcerans_Agy99 --
MMAR_3156|M.marinum_M --