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MTVSASSDRILSEAANLGAGPPRRVIDLRRGGRALGGSYLYEGDALITGWHSHDVHQIEYALHGVVEVET DSAHYLLPPQQAAWIPAGLEHQAVMNPDVKTVAVMFDPTLIPDGGDRARILAVSPLIREMMIYALRWHIE RGPGAGDDDGVADGFFRTLAALVCEALDHEAPLSLPTSDNPIVAAAMAYTKQHLDTVTCEEVSRAVSVSE RTLRRLFAETLGLPWRTYLLHARMLRAMALLTAPTQSVQGTATAVGFDSVSSFTRAFTQFCGETPSAYRK RVADASD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4276 | - | - | 100% (287) | AraC family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1013 | - | 2e-10 | 27.72% (184) | helix-turn-helix domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3612 | - | 3e-09 | 32.63% (95) | helix-turn-helix domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3863 | - | 4e-20 | 29.66% (236) | AraC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2370 | - | 1e-143 | 89.16% (286) | AraC family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3833 | - | 4e-20 | 29.66% (236) | AraC family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1337c | - | 9e-24 | 32.47% (231) | AraC family transcriptional regulator |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_0193 | - | 6e-21 | 30.34% (234) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_6546 | - | 1e-122 | 79.70% (271) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_2340 | - | 1e-118 | 75.97% (283) | transcriptional regulatory protein |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4276|M.vanbaalenii_PYR-1 MTVSASSDRILSEAANLGAGPPRRVIDLRRGGRALGGSYLYEGDALITGW
Mflv_2370|M.gilvum_PYR-GCK MTVSASSDRVLSETANL---SPRRVIDLRRGGRALGGSYLYEGDELITGW
MSMEG_6546|M.smegmatis_MC2_155 ----------MTETANL----TRPVIELRRGGRALAGSYLYEGEGLITGW
TH_2340|M.thermoresistible__bu VTVSALSARNLASSAKP------PQIDLRRGGRALGGSYLYEGDKLQTGW
Mb3863|M.bovis_AF2122/97 ------------------------MSENSHHRLATTSLTLPPGARIER--
Rv3833|M.tuberculosis_H37Rv ------------------------MSENSHHRLATTSLTLPPGARIER--
MAV_0193|M.avium_104 ------------------------MSEIGQHGLATSAQTLPPGARIAR--
MAB_1337c|M.abscessus_ATCC_199 ------------------------MLIN---RHLTGVMSVAGGHRINR--
: * :
Mvan_4276|M.vanbaalenii_PYR-1 HSHDVHQIEYALHGVVEVETDSAHYLLPPQQAAWIPAGLEHQAVMNPDVK
Mflv_2370|M.gilvum_PYR-GCK HSHDVHQIEYALHGVVEVETDSAHYLLPPQQAAWIPAGLEHQAVMNPDVK
MSMEG_6546|M.smegmatis_MC2_155 HSHEVHQIEYALHGVVEVETDAAHYLLPPQQAAWIPAGLQHQAVMNPDVK
TH_2340|M.thermoresistible__bu HSHDVHQIEYAIGGVVEVQTRTGHYLLPPQQAAWLPVGLEHSATMNPDVK
Mb3863|M.bovis_AF2122/97 HRHPSHQIVYPSAGAVSVTTHAGTWITPVNRAIWIPAGCWHQHKFHGHTQ
Rv3833|M.tuberculosis_H37Rv HRHPSHQIVYPSAGAVSVTTHAGTWITPVNRAIWIPAGCWHQHKFHGHTQ
MAV_0193|M.avium_104 HRHPLHQIVYPSTGAVSVTTPAGTWITPANRAIWIPAGCWHEHKFHGHTN
MAB_1337c|M.abscessus_ATCC_199 HWHQEHQIVYPASGVLAVTTDEGTWIAPPNRALWIPSGAGHEHRFYGPTQ
* * *** *. *.: * * . :: * ::* *:* * *. : .:
Mvan_4276|M.vanbaalenii_PYR-1 TVAVMFDPTLIPDGGDRARILAVSPLIREMMIYALRWHIERGPG-AGDDD
Mflv_2370|M.gilvum_PYR-GCK TVAVMFDPALIADGGDRARILAVSPLIREMMIYALRWPIDRGPADAASDD
MSMEG_6546|M.smegmatis_MC2_155 TVAVMFDPQMIPDGGTRARIIAVSPLIREMMIYGLRWPIDRADG-----D
TH_2340|M.thermoresistible__bu TVAVMFDPQLVPDAGNRARILAVSPLIREMMIYALRWPIDRPHG-----D
Mb3863|M.bovis_AF2122/97 FHGVALDPQRYRGGPATPTVLAVNPLMRELIIACSQADRTDTDE------
Rv3833|M.tuberculosis_H37Rv FHGVALDPQRYRGGPATPTVLAVNPLMRELVIACSQADRTDTDE------
MAV_0193|M.avium_104 FHGVALDPARYRRGPAAPAVLAVTPLMRELIIACSRARDTDAGA------
MAB_1337c|M.abscessus_ATCC_199 FHSVAFDPGVYPVELASPTVIAVSPLLRELIITCSDPGDLPEEE------
.* :** . ::**.**:**::*
Mvan_4276|M.vanbaalenii_PYR-1 GVADGFFRTLAALVCEALDHEAPLSLPTSDNPIVAAAMAYTKQHLDTVTC
Mflv_2370|M.gilvum_PYR-GCK TVADGFFRTMAALVCEALDHEAPLSLPTSDHPIVAAALDYTKRHLDTATA
MSMEG_6546|M.smegmatis_MC2_155 EISDGFFQTLANLVAEALDHEAPLSLPTSDNPIVAAALAYTKEHLDSVTA
TH_2340|M.thermoresistible__bu EISDTFFRTLAHLVSEALDHEAPLSLPTSDHPIVAAAMAYTKEHLQSVTA
Mb3863|M.bovis_AF2122/97 --HHRMLAVLQDQLPTTSIREPLWVPSPTDRRLRHACALIADNLTQPLTL
Rv3833|M.tuberculosis_H37Rv --HHRMLAVLQDQLPTTSIREPLWVPSPTDRRLRHACALIADNLTQPLTL
MAV_0193|M.avium_104 --HHRMLAVLHDQLQATSVAEPLWIPTAVDGRLRAACALIADNLREPLTL
MAB_1337c|M.abscessus_ATCC_199 --VARLRVVLIDQLR-HSPEQALRLPTPHDERLAEACALVEEDLTQVWTV
: .: : :. .. * : *. . : *
Mvan_4276|M.vanbaalenii_PYR-1 EEVSRAVSVSERTLRRLFAETLGLPWRTYLLHARMLRAMALLTAPTQSVQ
Mflv_2370|M.gilvum_PYR-GCK EEVSRAVSVSERTLRRLFADTLGLPWRTYLLHARMLRAMAPLAAPAQSVQ
MSMEG_6546|M.smegmatis_MC2_155 EQVSRAVSVSERTLRRLFADTIGMSWRTYLLHARMLRAMALLADQDQSVQ
TH_2340|M.thermoresistible__bu EEVSRAVAVSERTLRRQFRQATGISWRTYLLHARMLKAMALLAAPDQSVQ
Mb3863|M.bovis_AF2122/97 QQIGGRIGVSQRTLSRLFSDELGMTFPQWRTQLRLQHALVLLAE-RHDVT
Rv3833|M.tuberculosis_H37Rv QQIGGRIGVSQRTLSRLFSDELGMTFPQWRTQLRLQHALVLLAE-RHDVT
MAV_0193|M.avium_104 RQIGERIGVGQRTLSRLFRDELAMTFPQWRTQVRLQHALVLLAE-RRDVT
MAB_1337c|M.abscessus_ATCC_199 ADLGRRVGASERTLTRLFRTDMGMTYPQWRTQIRLHHALRLLAE-DRPVT
::. :...:*** * * .:.: : : *: :*: *: : *
Mvan_4276|M.vanbaalenii_PYR-1 GTATAVGFDSVSSFTRAFTQFCGETPSAYRKRVADASD----------
Mflv_2370|M.gilvum_PYR-GCK ETATAVGFDSVSSFTRAFAQFCGETPSAYRKRVADSD-----------
MSMEG_6546|M.smegmatis_MC2_155 ATATAVGFENLSSFTRCFAQFCGETPSNYRRRATGS------------
TH_2340|M.thermoresistible__bu ETASAVGFDSLSAFTRAFTQFCGETPSAYRHRISTDPHSRPTSADPIG
Mb3863|M.bovis_AF2122/97 SVASECGWATPSAFIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
Rv3833|M.tuberculosis_H37Rv SVASECGWATPSAFIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
MAV_0193|M.avium_104 SVAAECGWATPSAFIDTYRRAFGHTPGRLAP-----RPS---------
MAB_1337c|M.abscessus_ATCC_199 YVAHQCGWATPSAFIDVYRRTLGQTPGTYAAP-----VTR--------
.* *: . *:* : : *.**.