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VNPNDAGVPPLAFVQMLESPAFDPDAVARLRNIMAREGTDEATLIQRDIQAPLRWFREAYPGLDIDQATL LGFALAEQAQLTSFGPLSVPLVSAGSVAEIVELLTYLPLITTAVKAQFHPDDQGLTVGLWGHTSDRALDC LAVTYAGLALLRLLDMLVRAAPTLTLHLSWPAPAALKDREDDLTAGRLFFDAPMSFLHVPADTLNEVCRF SDPVAYRLAIVDLQRTLDQRSETTSFSEKVRRLLQKEPGRRSKHWFAHELSMSTSTLKRRLSEEETTFRE LRQAFLRERAMLQLLDRSLSVSEIATDLGYSDLANFSHAFKRWTGRSPSEFRLSPH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3156 | - | - | 100% (336) | AraC/XylS family transcriptional regulator |
| M. marinum M | MMAR_3320 | - | 3e-11 | 26.62% (293) | AraC/XylS family transcriptional regulator |
| M. marinum M | MMAR_5276 | - | 5e-08 | 24.26% (272) | AraC/XylS family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1430 | - | 1e-14 | 25.44% (342) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4594 | - | 1e-142 | 76.20% (332) | helix-turn-helix domain-containing protein |
| M. tuberculosis H37Rv | Rv1395 | - | 1e-14 | 25.44% (342) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2050 | - | 1e-117 | 65.66% (332) | putative HTH-type transcriptional regulator AraC |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_4601 | - | 3e-06 | 35.35% (99) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_3718 | - | 5e-12 | 29.86% (144) | PUTATIVE putative aldehyde dehydrogenase |
| M. ulcerans Agy99 | MUL_4350 | - | 4e-08 | 29.27% (123) | AraC/XylS family transcriptional regulator |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3156|M.marinum_M ---------MNPNDAGVPPLAFVQMLESPAFDPDAVARLRNIMAREGTDE
Mflv_4594|M.gilvum_PYR-GCK MDWAQGARSVKFSNAGVPPVAFVQMLESQALDPDAVARLRTIMAREGTDE
MAB_2050|M.abscessus_ATCC_1997 ---------MKLDDSGMPALAFLQMLDSEALGHDASIALRSIMVREHVTE
Mb1430|M.bovis_AF2122/97 --MGHLPPPAEVRHPVYATRVLCEVANERGVPTADVLAGTAIEPADLDDP
Rv1395|M.tuberculosis_H37Rv --MGHLPPPAEVRHPVYATRVLCEVANERGVPTADVLAGTAIEPADLDDP
TH_3718|M.thermoresistible__bu ----------------VAAADLIDTAVEAGIPADRCLRGTWLTRSDLAAA
MUL_4350|M.ulcerans_Agy99 ----------MSVVRGTGLSNYPNLVSELGGDPAALLRAAGVREQDVGNY
MSMEG_4601|M.smegmatis_MC2_155 -------------------------MRTTVETHDNLARDVLALATDYSYG
:
MMAR_3156|M.marinum_M ATLIQRDIQAPLRWFREAYPGLDIDQATLLGFALAEQAQLTSFGPLSVPL
Mflv_4594|M.gilvum_PYR-GCK ATLMQHDVQAPLRWFRDLYPDLDVDRATLLGFSFAGQAQLTSFGPLSVPL
MAB_2050|M.abscessus_ATCC_1997 SMLVGRDAQVPLRWFREIYSDFDCDQGTRLGFAFAEHAKLTSFGALSVPL
Mb1430|M.bovis_AF2122/97 DAVVG--ALDEITAVRRLLARLPDDAG--IGIDVGSRFALTHFGLFGFAV
Rv1395|M.tuberculosis_H37Rv DAVVG--ALDEITAVRRLLARLPDDAG--IGIDVGSRFALTHFGLFGFAV
TH_3718|M.thermoresistible__bu DRLIT--AEQELRIVRNVLAATEHPTA--LAGSAGARYQLPRAGFLGFAL
MUL_4350|M.ulcerans_Agy99 DAFIP-----VRAVIRAIETAAAATGTHDFGRQLAQRQGIEILGPVGVAA
MSMEG_4601|M.smegmatis_MC2_155 EVLAP------------------------------HRHRRAQF------L
. :
MMAR_3156|M.marinum_M VSAGSVAEIVEL-LTYLPLITTAVKAQFHPDDQGLTVGLWGHTSDRALDC
Mflv_4594|M.gilvum_PYR-GCK VSAGSVAEIVEL-LTYLPLITTAINAQFRPNDQGLTVGLWGHTGDRALDC
MAB_2050|M.abscessus_ATCC_1997 VSAGSVAEVVEL-LAYLPVITTALSPSFHSTERGLTIGLTGRTGDAGLNC
Mb1430|M.bovis_AF2122/97 MSCGTLRELLTIAMRYFALTTMHVDITLFETADDCLVELDASHLPADVRG
Rv1395|M.tuberculosis_H37Rv MSCGTLRELLTIAMRYFALTTMHVDITLFETADDCLVELDASHLPADVRG
TH_3718|M.thermoresistible__bu LSSNTLGDAIRVGIRFWRLTSVFERVTLEVNRQTTAIVLDDRDVPADVRQ
MUL_4350|M.ulcerans_Agy99 RTAATVADALMIFHTFMAAYSPAIHIEITPLARTQRSVVAIEIVPDDP--
MSMEG_4601|M.smegmatis_MC2_155 YGVGGTMDVRTEHGSWLVPTERAVLIPPQTQHAVTMWGVSTRSLYIEPGA
: : :
MMAR_3156|M.marinum_M LAVTYAGLALLRLLD---MLVRAAPTLTLHLSWPAPAALKDREDDLT-AG
Mflv_4594|M.gilvum_PYR-GCK LAVTYTGSALLRLLD---MLVSDALTVTLHLSWSAPVSLNKLAAEMVLAG
MAB_2050|M.abscessus_ATCC_1997 LAVTYGGLALLRLLD---MLAGAVPNIELHLSHSAPESW--VLHDEVLAG
Mb1430|M.bovis_AF2122/97 FFIERDIAGIIATTTSFALPLAAKYADQVSAELAVDAELLRPLLELVPVH
Rv1395|M.tuberculosis_H37Rv FFIERDIAGIIATTTSFALPLAAKYADQVSAELAVDAELLRPLLELVPVH
TH_3718|M.thermoresistible__bu FLVERDAATMVGVTP--AL-LGGPLPDGVRMSLRRRPNGDAAVEELV---
MUL_4350|M.ulcerans_Agy99 IPCPHTLELALGVSLGVFRLLMGADYTPLAVHLPHDPLTPPTTYVRYFEC
MSMEG_4601|M.smegmatis_MC2_155 VPWFPTRCTVVDVPT----LLRELLVAAVAVPLDRPPDAR----------
. : :
MMAR_3156|M.marinum_M RLFFDAPMSFLHVPADTLNEVCRFSDPVAYRLAIVDLQRTLDQRSETTSF
Mflv_4594|M.gilvum_PYR-GCK RLFFDAPMSYLHVPVNALNEVCRFSDPLAYRLAVAELRRTLDEQSGATSF
MAB_2050|M.abscessus_ATCC_1997 RIFFDAPSSFVHVPAATLEEVCRFSDPVAYRIAVTDLQRTLDQRR-DTSV
Mb1430|M.bovis_AF2122/97 DVAFGRAHNRVHFPRAMFDEPLPQADRHTLEMCIAQCDVLMQRNERRRGI
Rv1395|M.tuberculosis_H37Rv DVAFGRAHNRVHFPRAMFDEPLPQADRHTLEMCIAQCDVLMQRNERRRGI
TH_3718|M.thermoresistible__bu DVSYGADRNAITFPTALLDRPLAAANPAVAAQCIAQCDELLARHQDEPTV
MUL_4350|M.ulcerans_Agy99 TPHFAERRSGFTVRSTDLVRPLHRDELAHRAVVDYLSSITPLGAGIVESV
MSMEG_4601|M.smegmatis_MC2_155 ----DAALFALTLHEVAGCTSLPLDLPLPQPGALSEQCRRFLAAPRIDTT
. .
MMAR_3156|M.marinum_M SEKVRRLLQKEPGRR-SKHWFAHELSMSTSTLKRRLSEEETTFRELRQAF
Mflv_4594|M.gilvum_PYR-GCK SKKVRRLLDEDPGQR-SCQRVADELSVSTSTLKRRLAEEGTTFRELRQSC
MAB_2050|M.abscessus_ATCC_1997 SEKVRDLLEKDPGKT-NISRTAGELSISPSTLKRRLREEGTTFRELRQSF
Mb1430|M.bovis_AF2122/97 TALVRSKLFRDSGLFPTFTDVAGELDMHPRTLRRRLAEEGTSFRALLGEA
Rv1395|M.tuberculosis_H37Rv TALVRSKLFRDSGLFPTFTDVAGELDMHPRTLRRRLAEEGTSFRALLGEA
TH_3718|M.thermoresistible__bu ASRVRRRLARDPGAVPLMRTLATEMGFTERTLRRRLAREGTGYRSLIDEV
MUL_4350|M.ulcerans_Agy99 RTMARQLLPTG---ATTLEVVAAQFHLHPKTLQRRLADESTTFAALIDEV
MSMEG_4601|M.smegmatis_MC2_155 TG-----------------WWANALHVSERTVARLFRKELSMTVAEWQRR
* : . *: * : * :
MMAR_3156|M.marinum_M LRERAMLQLLDRSLSVSEIATDLGYSDLANFSHAFKRWTGRSPSEFRLSP
Mflv_4594|M.gilvum_PYR-GCK LRESAMMLLITRSMSASQIATELGYGDLANFSHAFKRWTGRSPSEYRRSQ
MAB_2050|M.abscessus_ATCC_1997 LQERAILRILDRSVSVSEIAAELGYADLTNFTHAFKRWTGRSPRHFRKTR
Mb1430|M.bovis_AF2122/97 RSTVAVDLLRNVGLTVQQVSTRLGYTEVSTFSHAFKRWYGVAPSEYSRRG
Rv1395|M.tuberculosis_H37Rv RSTVAVDLLRNVGLTVQQVSTRLGYTEVSTFSHAFKRWYGVAPSEYSRRG
TH_3718|M.thermoresistible__bu RGARAADLLS-GGATVKQVAQQLGYSEPAAFHHAFVRWHALPPARFRRAD
MUL_4350|M.ulcerans_Agy99 RKETADRYLRTTAMSLSHLARELGYAEQSVLTRSCKRWFGIGPAAYRAKT
MSMEG_4601|M.smegmatis_MC2_155 ACVLHSLRQLTQGVAVSAVASDLGYSSPAAFSTMFSRALGTSPSAFSPRR
. : . :: *** . : : * . * :
MMAR_3156|M.marinum_M H--------
Mflv_4594|M.gilvum_PYR-GCK R--------
MAB_2050|M.abscessus_ATCC_1997 D--------
Mb1430|M.bovis_AF2122/97 ---------
Rv1395|M.tuberculosis_H37Rv ---------
TH_3718|M.thermoresistible__bu VR-------
MUL_4350|M.ulcerans_Agy99 RVRATPRRR
MSMEG_4601|M.smegmatis_MC2_155 LNL------