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MKTTRRVLGTLIATTALVVAACGTNTSESASTADPDSLYGGTLRIASVEDIDALDPLIAYSAESWQVIRA TTRQLVTYPGSKEGIGDDTTVVPDLAESWDVSPDRKTYTFHLRDNITFSGASNREITAHDFVYAVKRFPD PNAQVSAITYFNATFDGFEEYAAEFAKVPTGDLAAVKQFIDTHEIRGFKALDDKTLQLTLTEPASDILDI LTLNFVTPLPEEVTSKYFADSLEFRKNYVSSGPYHIESYDQGKQLTLARVPEYNSEGDPRKAYADKIVFD TTVASADAASQQLQTGTADIALYVRSFPANVIAQYKRTDPDHLHSSASGSAVFISWNNPAEPATPAQAAL KDLKVRQAVNYSLNRADVVRGLGGPDSAIPSNEILTSTTLGFNDENPYPTPEDKGDPDKAKALLADSGHK DLTLSAAYRNTPEFEKIATSVQNALARSGITLRLVPIAGDSWGAFRAYLADKSNLDQWDLAITTWTPDWQ GNSARMTLGGWLNSDFAPGGTWNGVTYHNPQLNAAAARAFAAADPTADWKEANRIASADLAWFPLIERVK TIPTSDRVTNWTWQSLGNNADITNISVNS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4545 | - | - | 100% (589) | extracellular solute-binding protein, family protein 5 |
| M. smegmatis MC2 155 | MSMEG_0643 | - | 1e-29 | 27.83% (460) | extracellular solute-binding protein, family protein 5, |
| M. smegmatis MC2 155 | MSMEG_4354 | - | 2e-19 | 24.17% (480) | dipeptide-binding protein of ABC transport system |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3690c | dppA | 5e-16 | 23.00% (500) | periplasmic dipeptide-binding lipoprotein DppA |
| M. gilvum PYR-GCK | Mflv_2761 | - | 6e-19 | 23.52% (523) | extracellular solute-binding protein |
| M. tuberculosis H37Rv | Rv3666c | dppA | 1e-14 | 22.60% (500) | periplasmic dipeptide-binding lipoprotein DppA |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0426 | - | 1e-06 | 21.49% (377) | peptide ABC transporter DppA |
| M. marinum M | MMAR_5154 | dppA | 1e-12 | 23.72% (607) | periplasmic dipeptide-binding lipoprotein DppA |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4152 | - | 8e-13 | 22.11% (475) | PUTATIVE extracellular solute-binding protein, family 5 |
| M. ulcerans Agy99 | MUL_4240 | dppA | 1e-12 | 23.72% (607) | periplasmic dipeptide-binding lipoprotein DppA |
| M. vanbaalenii PYR-1 | Mvan_0438 | - | 5e-32 | 27.27% (462) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2761|M.gilvum_PYR-GCK -----------------------------------------MARTAVGAA
TH_4152|M.thermoresistible__bu -------------------------------------------------V
Mb3690c|M.bovis_AF2122/97 ---------------------------------------------MVRRM
Rv3666c|M.tuberculosis_H37Rv ---------------------------------------------MVRQM
MMAR_5154|M.marinum_M ----------------------------------------------MRRM
MUL_4240|M.ulcerans_Agy99 MPLMAWGERRRDIANAPIAIRTAPMTMSRVPGALLGGAAGGSMVAVMRRM
MAB_0426|M.abscessus_ATCC_1997 ----------------------------------------------MRLR
Mvan_0438|M.vanbaalenii_PYR-1 ----------------------------------------MHIFRRALII
MSMEG_4545|M.smegmatis_MC2_155 -------------------------------------MKTTRRVLGTLIA
Mflv_2761|M.gilvum_PYR-GCK VLAVCALVLSLTGCNTGERVDLGDGAGGALIAAIAGEPDQLDPHKTTAYF
TH_4152|M.thermoresistible__bu SNLVAVLLIAATGCAPGQRVDLGDLSG-NLIAAIAGEPDQLDPHKTSAYF
Mb3690c|M.bovis_AF2122/97 RAALAALATGLLVLAPVAGCGGGVLSPDVVLVNGGEPPNPLIPTGTNDSN
Rv3666c|M.tuberculosis_H37Rv RAALAALATGLLVLAPVAGCGGGVLSPDVVLVNGGEPPNPLIPTGTNDSN
MMAR_5154|M.marinum_M RATLAVVAV-LLAVSPVAACGGGVLSPDLVLVNGGEPPNPLIPTGTNDSY
MUL_4240|M.ulcerans_Agy99 RATLAVVAV-LLAVSPVAACGGGVLSPDLVLVNGGEPPNPLIPTGTNDSY
MAB_0426|M.abscessus_ATCC_1997 RLAIVLLVGIVAVLPAGCGDLVTPAPPGYFSMYITEPEHTLVPGNTTENQ
Mvan_0438|M.vanbaalenii_PYR-1 ACVASLAAFGVAACGSDDSSGGGGGSGGDITVNATSFPDYIDPQLSYTVE
MSMEG_4545|M.smegmatis_MC2_155 TTALVVAACGTNTSESASTADPDSLYGGTLRIASVEDIDALDPLIAYSAE
. . . : * :
Mflv_2761|M.gilvum_PYR-GCK SFEVLENVFDTLVEPDQD-------LQMKPALAESWEVS-PDQLTWTFRL
TH_4152|M.thermoresistible__bu SFQVLENVFDTLVEPDED-------LRMRPALAESWQVS-ADQRVWTFRL
Mb3690c|M.bovis_AF2122/97 GGRIIDRLFAGLMSYD---------AVGKPSLEVAQSIESADNVNYRITV
Rv3666c|M.tuberculosis_H37Rv GGRIIDRLFAGLMSYD---------AVGKPSLEVAQSIESADNVNYRITV
MMAR_5154|M.marinum_M GGRIIDRLFAGLVSYD---------AKGKPSLEVAQSIDTTDNVNYRILL
MUL_4240|M.ulcerans_Agy99 GGRIIDRLFAGLVSYD---------AKGKPSLEVAQSIDTTDNVNYRILL
MAB_0426|M.abscessus_ATCC_1997 GGRILRSLFTALVEFNNE-------TAAVEYTGVAESITSHDNVNWTIKL
Mvan_0438|M.vanbaalenii_PYR-1 GWEVLWNVYTPLLTYRHARGKE--GTEVVPALAEALPDISPDGKTYKLKL
MSMEG_4545|M.smegmatis_MC2_155 SWQVIRATTRQLVTYPGSKEGIGDDTTVVPDLAESWDVS-PDRKTYTFHL
. .:: *: : * : : :
Mflv_2761|M.gilvum_PYR-GCK RPGVTFHDGT--PLAAEDVVFSYRR---------IIDEQLANSDKFSSVQ
TH_4152|M.thermoresistible__bu RPGVTFHDGS--PLTADDVVFSYRR---------IIDEHLTNVDRLSAVT
Mb3690c|M.bovis_AF2122/97 KPGWKFTDGS--PVTAHSFVDAWNYGA-LSTNAQLQQHFFSPIEGFDDVA
Rv3666c|M.tuberculosis_H37Rv KPGWKFTDGS--PVTAHSFVDAWNYGA-LSTNAQLQQHFFSPIEGFDDVA
MMAR_5154|M.marinum_M KPGWRFTDGS--PVTAHSFVDAWNYGA-LSTNAQLQQHFFSPIEGYEEVA
MUL_4240|M.ulcerans_Agy99 KPGWGFTDGS--PVTAHSFVDAWNYGA-LSTNAQLQQHFFSPIEGYEEVA
MAB_0426|M.abscessus_ATCC_1997 KPGWTFHNGE--PVTAQSYVDAWNYTA-LSTNAQGSSSFLANVDGFDDLQ
Mvan_0438|M.vanbaalenii_PYR-1 RPNMKYSDGT--PIKASDFTYAIQR---LFKTDSGGSVFYNVIAGATEYA
MSMEG_4545|M.smegmatis_MC2_155 RDNITFSGASNREITAHDFVYAVKRFPDPNAQVSAITYFNATFDGFEEYA
: . : .. : * . . : .
Mflv_2761|M.gilvum_PYR-GCK ---------------AVEAPDPS---------TVVIRVDRPTPNMLTNLG
TH_4152|M.thermoresistible__bu ---------------EVTAVDPL---------TVRITVARPTPNLLTNLG
Mb3690c|M.bovis_AF2122/97 GAPGDKSR---TTMSGLRVVNDL---------EFTVRLKAPTIDFTLRLG
Rv3666c|M.tuberculosis_H37Rv GAPGDKSR---TTMSGLRVVNDL---------EFTVRLKAPTIDFTLRLG
MMAR_5154|M.marinum_M GEPGEGKP---TTMSGLHVVNNR---------EFTVRLRAPTIDFMLSLG
MUL_4240|M.ulcerans_Agy99 GEPGEGKP---TTMSGLHVVNNR---------EFTVRLRAPTIDFMLSLG
MAB_0426|M.abscessus_ATCC_1997 GDPAHKIAPRATQMRGLHVVDDV---------TFTVRLNTPFAIYPMTLG
Mvan_0438|M.vanbaalenii_PYR-1 DGAADTIT-------GITTDDGTG--------DITIQLTEPNGTFDNLLG
MSMEG_4545|M.smegmatis_MC2_155 AEFAKVPTGDLAAVKQFIDTHEIRGFKALDDKTLQLTLTEPASDILDILT
. . . : : * *
Mflv_2761|M.gilvum_PYR-GCK GFKGMAIVSRAN----VESGRIATHPVGTGPFSFLGQ--------KSGDS
TH_4152|M.thermoresistible__bu GFKGMAIVQRAN----VETGRIATHPVGTGPFEFRGA--------RSGDS
Mb3690c|M.bovis_AF2122/97 HSSFYPLPDSAF----RDMAAFGRNPIGNGPYKLADGPAG--PAWEHNVR
Rv3666c|M.tuberculosis_H37Rv HSSFYPLPDSAF----RDMAAFGRNPIGNGPYKLADGPAG--PAWEHNVR
MMAR_5154|M.marinum_M HSSFYPLPEAAF----KDMAAFGRNPIGNGPYRLDSGGEE--PAWEHNVK
MUL_4240|M.ulcerans_Agy99 HSSFYPLPEAAF----KDMAAFGRNPIGNGPYRLDSGGEE--PAWEHNVK
MAB_0426|M.abscessus_ATCC_1997 YTAFLPLPKAFF----RDPVKFGVHPIGNGPFKADG-------DWVRGVG
Mvan_0438|M.vanbaalenii_PYR-1 LMFAAPIPQSTP----LDADATNNPPPASGPFMFTTVDAPRTLTMERNPQ
MSMEG_4545|M.smegmatis_MC2_155 LNFVTPLPEEVTSKYFADSLEFRKNYVSSGPYHIES--------YDQGKQ
.: . : ..**: .
Mflv_2761|M.gilvum_PYR-GCK ISLRANPDYWAG-PPGVAGVTFRFI----PEPSTALSALQAGEVDWTDS-
TH_4152|M.thermoresistible__bu ITLVANDDHWAG-PPRLNGVTFRFI----SEPATALSALQAGEIDWTDA-
Mb3690c|M.bovis_AF2122/97 IDLVPNPDYHGNRKPRNKGLRFEFY----ANLDTAYADLLSGNLDVLDT-
Rv3666c|M.tuberculosis_H37Rv IDLVPNPDYHGNRKPRNKGLRFEFY----ANLDTAYADLLSGNLDVLDT-
MMAR_5154|M.marinum_M IDLVPNPDYRGNRKPRNKGLRFEFY----ANLETAYSDLLSGNLDVLDT-
MUL_4240|M.ulcerans_Agy99 IDLVPNPDYRGNRKPRNKGLRFEFY----ANLETAYSDLLSGNLDVLDT-
MAB_0426|M.abscessus_ATCC_1997 FTLSRYDQYAGEKKAKAKGLIWRVY----TEGLTAYTDMQAGALDIQLD-
Mvan_0438|M.vanbaalenii_PYR-1 FQTVKDAGADEVADAGVDKITLIEN----KNQSAQVTDIMQNKVDFMMDP
MSMEG_4545|M.smegmatis_MC2_155 LTLARVPEYNSEGDPRKAYADKIVFDTTVASADAASQQLQTGTADIALYV
: . . : : . *
Mflv_2761|M.gilvum_PYR-GCK --VPPQRVSQLRDDESLQLTVTPSNDYWYLALN----QARAPWNDVR---
TH_4152|M.thermoresistible__bu --IPTQRVTQLRNDDSLTLAVTPSNDYWYLALN----HARAPWHDLR---
Mb3690c|M.bovis_AF2122/97 --IPPSALTVYQRDLGDHATSGPAAINQTLDTP----LRLPHFGGEEGRL
Rv3666c|M.tuberculosis_H37Rv --IPPSALTVYQRDLGDHATSGPAAINQTLDTP----LRLPHFGGEEGRL
MMAR_5154|M.marinum_M --IPSSALTVYGRDLGDNATSGPAAINQTLDTP----LRLAHFGGEEGRL
MUL_4240|M.ulcerans_Agy99 --IPSSALTVYGRDLGDNATSGPAAINQTLDTP----LRLAHFGGEEGRL
MAB_0426|M.abscessus_ATCC_1997 --LPDAAYENAKAEFGSAYLERPRPDITSLGFP----MYDPRYRDVR---
Mvan_0438|M.vanbaalenii_PYR-1 --VPSDRLQEVKSRYSDRFRMEDSINTYYMFMN----TERAPFNDVR---
MSMEG_4545|M.smegmatis_MC2_155 RSFPANVIAQYKRTDPDHLHSSASGSAVFISWNNPAEPATPAQAALKDLK
.* : . .
Mflv_2761|M.gilvum_PYR-GCK VRQAIAYAIDRDAIVQATSYG-TAAANQLAIPEGNPWFTPYDRYREDGEE
TH_4152|M.thermoresistible__bu VRRAIAFGIDREAIVTATGYG-TATANQLAIPPGDFWYTHYDRYRYD---
Mb3690c|M.bovis_AF2122/97 RRLALSAAINRPQICQQIFAG-TRSPARDFTARSLPGFDPNLPGNEVLDY
Rv3666c|M.tuberculosis_H37Rv RRLALSAAINRPQICQQIFAG-TRSPARDFTARSLPGFDPNLPGNEVLDY
MMAR_5154|M.marinum_M RRLALSAAIDRPQICQQIFNG-TRSAARDFTARSLPGFDPHIPGNEALDF
MUL_4240|M.ulcerans_Agy99 RRLALSAAIDRPQICQQIFNG-TRSAARDFTARSLPGFDPHIPGNEALDF
MAB_0426|M.abscessus_ATCC_1997 VRQAISMAIDREAITQVIFSG-TRTPATSYGSAVVYGYRKGACG-KLCEL
Mvan_0438|M.vanbaalenii_PYR-1 VRQAINYAIDPEALN-RIFGG-RLHPTQQVLPPGMPGYQEYKLYPGP---
MSMEG_4545|M.smegmatis_MC2_155 VRQAVNYSLNRADVVRGLGGPDSAIPSNEILTSTTLGFNDENPYPTPEDK
* *: .:: : . . :
Mflv_2761|M.gilvum_PYR-GCK -GLETARDLLRQANAT----PGDLDMLVTTEYPETVTAAQIVADNLAPLG
TH_4152|M.thermoresistible__bu --LDRARALLDEARAAGVDPPRRLDMLVTGDYPQTVTAAQIIADNVAPLG
Mb3690c|M.bovis_AF2122/97 -DPQRARRLWAQADAIS-PWSGRYAIAYNADAGHRDWVDAVANSIKNVLG
Rv3666c|M.tuberculosis_H37Rv -DPQRARRLWAQADAIS-PWSGRYAIAYNADAGHRDWVDAVANSIKNVLG
MMAR_5154|M.marinum_M -NPQRARQLWAQANAIS-PWSGSYAIAYNADSGHQEWVDTVANSIKNVLG
MUL_4240|M.ulcerans_Agy99 -NPQRARQLWAQANAIS-PWSGSYAIAYNADSGHQEWVDAVANSIKNVLG
MAB_0426|M.abscessus_ATCC_1997 -HVDEANKLLDEAHFDR-NKPIELWYSS-SSTGALSWVQAIGNQLQSNLK
Mvan_0438|M.vanbaalenii_PYR-1 -DMDKARALIAEANPAD-----RDITVWTDDEPDRKRIGEYYHDLLTQLG
MSMEG_4545|M.smegmatis_MC2_155 GDPDKAKALLADSGHKD-----LTLSAAYRNTPEFEKIATSVQNALARSG
: *. * :: . .
Mflv_2761|M.gilvum_PYR-GCK ITVNIRTVDFATWLDEQ-------NSGNFDMLMMGWLGNID-PDDFYYAQ
TH_4152|M.thermoresistible__bu ITVDIRTVDFATWLDEQ-------NNGTFDMLMMGWLGNID-PDDYYYAQ
Mb3690c|M.bovis_AF2122/97 IDAVAAPQPTFAGFRTQIT-----NRAIDSAFRAGWQGDYP-SMIGFLAP
Rv3666c|M.tuberculosis_H37Rv IDAVAAPQPTFAGFRTQIT-----NRAIDSAFRAGWRGDYP-SMIEFLAP
MMAR_5154|M.marinum_M IEAMGAPQPTFAGLRTQIT-----NRTIDTAFRAGWQGDFP-SMIEFLAP
MUL_4240|M.ulcerans_Agy99 IEAMGAPQPTFAGLRTQIT-----NRTIDTAFRAGWQGDFP-SMIEFLAP
MAB_0426|M.abscessus_ATCC_1997 VPYLLKSLP-WSQFLPLQD-----GKGMTGPFRSGWVMDYP-SIYNFLES
Mvan_0438|M.vanbaalenii_PYR-1 FNATLKVIAGDVYWTTVGNQ----STPDVDTGFADWFQDFP-HPDDFFRP
MSMEG_4545|M.smegmatis_MC2_155 ITLRLVPIAGDSWGAFRAYLADKSNLDQWDLAITTWTPDWQGNSARMTLG
. . * :
Mflv_2761|M.gilvum_PYR-GCK HHT------DGTSNAQKFSNPEVDRLLDAGRVETDEQTRKAGYARAATLI
TH_4152|M.thermoresistible__bu HHT------DGASNAQRFSDPEVDRLLDAARAEPDRDRRKALYDRAATLI
Mb3690c|M.bovis_AF2122/97 LFT-----AGAGSNDVGYINPEFDAALAAAEAAPTLTESHELVNDAQRIL
Rv3666c|M.tuberculosis_H37Rv LFT-----AGAGSNDVGYINPEFDAALAAAEAAPTLTESHELVNDAQRIL
MMAR_5154|M.marinum_M LYG-----TGAGSNDVGYSNQEFDDALAAAAAAPTLQEADRLANVAQRIL
MUL_4240|M.ulcerans_Agy99 LYG-----TGAGSNDVGYSNQEFDDALAAAAAAPTLQEADRLANVAQRIL
MAB_0426|M.abscessus_ATCC_1997 LYGTV-ALPPNGSNYVFYSNPAFDELLRQGNNEPTVELATKAYQKAEDLL
Mvan_0438|M.vanbaalenii_PYR-1 LLHGDSILPTNGNNLSRANIAENNAKMDELVTKQITDEGVEQQYADLDRA
MSMEG_4545|M.smegmatis_MC2_155 GWLNSDFAPGGTWNGVTYHNPQLNAAAARAFAAADP---TADWKEANRIA
* :
Mflv_2761|M.gilvum_PYR-GCK ADEVSYIYLYNPSVIQAWNPALSGYEAR-RDGAVRFRSASLDSDGNV---
TH_4152|M.thermoresistible__bu ADRVSYLFLYNPAVVQAWSPDLSGYRAR-RDAAVRFRDASLNRDGLNRDG
Mb3690c|M.bovis_AF2122/97 FHDMPVVPLWDYISVVGWSSQVSNVTVT-WNGLPDYENIVKA--------
Rv3666c|M.tuberculosis_H37Rv FHDMPVVPLWDYISVVGWSSQVSNVTVT-WNGLPDYENIVKA--------
MMAR_5154|M.marinum_M FHDMPTIPLWDYIAVVGWSTEVSNVQVT-WNGLPDYENLVKA--------
MUL_4240|M.ulcerans_Agy99 FHDMPTIPLWDYIAVVGWSTEVSNVQVT-WNGLPDYENLVKA--------
MAB_0426|M.abscessus_ATCC_1997 FKDLPAAPLFYEVNQAVHSKRVRNVKIG-IQDCIEYADVEVVQ-------
Mvan_0438|M.vanbaalenii_PYR-1 YMEQAVWAPYGNEQFTTFLSERMDFDKS-YHHLLFKQDFTSFALK-----
MSMEG_4545|M.smegmatis_MC2_155 SADLAWFPLIERVKTIPTSDRVTNWTWQSLGNNADITNISVNS-------
. . .
Mflv_2761|M.gilvum_PYR-GCK --
TH_4152|M.thermoresistible__bu PP
Mb3690c|M.bovis_AF2122/97 --
Rv3666c|M.tuberculosis_H37Rv --
MMAR_5154|M.marinum_M --
MUL_4240|M.ulcerans_Agy99 --
MAB_0426|M.abscessus_ATCC_1997 --
Mvan_0438|M.vanbaalenii_PYR-1 --
MSMEG_4545|M.smegmatis_MC2_155 --