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MRLRRLAIVLLVGIVAVLPAGCGDLVTPAPPGYFSMYITEPEHTLVPGNTTENQGGRILRSLFTALVEFN NETAAVEYTGVAESITSHDNVNWTIKLKPGWTFHNGEPVTAQSYVDAWNYTALSTNAQGSSSFLANVDGF DDLQGDPAHKIAPRATQMRGLHVVDDVTFTVRLNTPFAIYPMTLGYTAFLPLPKAFFRDPVKFGVHPIGN GPFKADGDWVRGVGFTLSRYDQYAGEKKAKAKGLIWRVYTEGLTAYTDMQAGALDIQLDLPDAAYENAKA EFGSAYLERPRPDITSLGFPMYDPRYRDVRVRQAISMAIDREAITQVIFSGTRTPATSYGSAVVYGYRKG ACGKLCELHVDEANKLLDEAHFDRNKPIELWYSSSSTGALSWVQAIGNQLQSNLKVPYLLKSLPWSQFLP LQDGKGMTGPFRSGWVMDYPSIYNFLESLYGTVALPPNGSNYVFYSNPAFDELLRQGNNEPTVELATKAY QKAEDLLFKDLPAAPLFYEVNQAVHSKRVRNVKIGIQDCIEYADVEVVQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0426 | - | - | 100% (539) | peptide ABC transporter DppA |
| M. abscessus ATCC 19977 | MAB_0719 | - | 1e-15 | 22.87% (551) | putative oligopeptide ABC transporter, solute-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3690c | dppA | 2e-77 | 34.85% (548) | periplasmic dipeptide-binding lipoprotein DppA |
| M. gilvum PYR-GCK | Mflv_2761 | - | 1e-19 | 25.15% (517) | extracellular solute-binding protein |
| M. tuberculosis H37Rv | Rv3666c | dppA | 6e-77 | 34.67% (548) | periplasmic dipeptide-binding lipoprotein DppA |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_5154 | dppA | 2e-74 | 34.38% (541) | periplasmic dipeptide-binding lipoprotein DppA |
| M. avium 104 | MAV_0464 | - | 4e-77 | 35.53% (546) | extracellular solute-binding protein, family protein 5 |
| M. smegmatis MC2 155 | MSMEG_1084 | - | 7e-21 | 25.88% (537) | peptide/opine/nickel uptake family protein ABC transporter, |
| M. thermoresistible (build 8) | TH_4152 | - | 1e-18 | 22.69% (498) | PUTATIVE extracellular solute-binding protein, family 5 |
| M. ulcerans Agy99 | MUL_4240 | dppA | 6e-75 | 34.57% (541) | periplasmic dipeptide-binding lipoprotein DppA |
| M. vanbaalenii PYR-1 | Mvan_3773 | - | 9e-18 | 25.89% (336) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3690c|M.bovis_AF2122/97 ---------------------------------------------MVRRM
Rv3666c|M.tuberculosis_H37Rv ---------------------------------------------MVRQM
MMAR_5154|M.marinum_M ----------------------------------------------MRRM
MUL_4240|M.ulcerans_Agy99 MPLMAWGERRRDIANAPIAIRTAPMTMSRVPGALLGGAAGGSMVAVMRRM
MAV_0464|M.avium_104 --------------------------------------------------
MAB_0426|M.abscessus_ATCC_1997 ----------------------------------------------MRLR
Mflv_2761|M.gilvum_PYR-GCK -----------------------------------------MARTAVGAA
Mvan_3773|M.vanbaalenii_PYR-1 ----------------------------------------------MRTV
TH_4152|M.thermoresistible__bu -------------------------------------------------V
MSMEG_1084|M.smegmatis_MC2_155 ---------------------------------------------MRQSV
Mb3690c|M.bovis_AF2122/97 RAALAALATGLLVLAPVAGCGGGVLSPDVVLVNGGE-PPNPLIPTGTNDS
Rv3666c|M.tuberculosis_H37Rv RAALAALATGLLVLAPVAGCGGGVLSPDVVLVNGGE-PPNPLIPTGTNDS
MMAR_5154|M.marinum_M RATLAVVAV-LLAVSPVAACGGGVLSPDLVLVNGGE-PPNPLIPTGTNDS
MUL_4240|M.ulcerans_Agy99 RATLAVVAV-LLAVSPVAACGGGVLSPDLVLVNGGE-PPNPLIPTGTNDS
MAV_0464|M.avium_104 MAVLATAAAALLVVASLAGCGGGVLSPDLVVVNGGE-PPNPLVPTGTNDS
MAB_0426|M.abscessus_ATCC_1997 RLAIVLLVGIVAVLPAGCGDLVTPAPPGYFSMYITE-PEHTLVPGNTTEN
Mflv_2761|M.gilvum_PYR-GCK VLAVCALVLSLTGCNTGERVDLGDGAGGALIAAIAG-EPDQLDPHKTTAY
Mvan_3773|M.vanbaalenii_PYR-1 VLATCVFLAALTGCSPGDRVDLGAGAADALIAAIAG-EPDQLDPHKTTSY
TH_4152|M.thermoresistible__bu SNLVAVLLIAATGCAPGQRVDLGD-LSGNLIAAIAG-EPDQLDPHKTSAY
MSMEG_1084|M.smegmatis_MC2_155 TRLHATLLSVIVAIAALAGCSRGPVQTGNVFVIAIESEADILDPQVAGGW
. . . . * * :
Mb3690c|M.bovis_AF2122/97 NGGRIIDRLFAGLMSYD----------AVGKPSLEVAQSIESADNVNYRI
Rv3666c|M.tuberculosis_H37Rv NGGRIIDRLFAGLMSYD----------AVGKPSLEVAQSIESADNVNYRI
MMAR_5154|M.marinum_M YGGRIIDRLFAGLVSYD----------AKGKPSLEVAQSIDTTDNVNYRI
MUL_4240|M.ulcerans_Agy99 YGGRIIDRLFAGLVSYD----------AKGKPSLEVAQSIDTTDNVNYRI
MAV_0464|M.avium_104 QGGRILDRLFAGLMSYD----------AAGNPAPEVAQSIESGDNVNYRI
MAB_0426|M.abscessus_ATCC_1997 QGGRILRSLFTALVEFNN--------ETAAVEYTGVAESITSHDNVNWTI
Mflv_2761|M.gilvum_PYR-GCK FSFEVLENVFDTLVEPDQ--------DLQMKPALAESWEVSP-DQLTWTF
Mvan_3773|M.vanbaalenii_PYR-1 FSFEVLENVFDTLVEPDG--------NLQMQPALARAWEVSP-DQLTWTF
TH_4152|M.thermoresistible__bu FSFQVLENVFDTLVEPDE--------DLRMRPALAESWQVSA-DQRVWTF
MSMEG_1084|M.smegmatis_MC2_155 VSWRINRQIFEPLVDEDLSMPSSEATVPPLRPGLAESWDISD-DGLEYTF
. .: :* *:. : : .: * : :
Mb3690c|M.bovis_AF2122/97 TVKPGWKFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGFDDVAG
Rv3666c|M.tuberculosis_H37Rv TVKPGWKFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGFDDVAG
MMAR_5154|M.marinum_M LLKPGWRFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGYEEVAG
MUL_4240|M.ulcerans_Agy99 LLKPGWGFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGYEEVAG
MAV_0464|M.avium_104 VLKPGWRFTDGSPVTAHSFVDAWNYGALSTNAQLQQSFFSPIDGYDALAA
MAB_0426|M.abscessus_ATCC_1997 KLKPGWTFHNGEPVTAQSYVDAWNYTALSTNAQGSSSFLANVDGFDDLQG
Mflv_2761|M.gilvum_PYR-GCK RLRPGVTFHDGTPLAAEDVVFSYRR--------IIDEQLANSDKFSSVQA
Mvan_3773|M.vanbaalenii_PYR-1 HLRPGVTFHDGTPLTADDVVFSYRR--------IIDEQLANSDKFSSVAA
TH_4152|M.thermoresistible__bu RLRPGVTFHDGSPLTADDVVFSYRR--------IIDEHLTNVDRLSAVTE
MSMEG_1084|M.smegmatis_MC2_155 HIRKDVKFHDGTPLDARAVEYNVRR-MWDKSSPMYNARAAGQTGFVWKFL
:: . * :* *: * . . :
Mb3690c|M.bovis_AF2122/97 APGDKSR---TTMSGLRVVNDLEFTVRLKAPTIDFTLRLG----HSSFYP
Rv3666c|M.tuberculosis_H37Rv APGDKSR---TTMSGLRVVNDLEFTVRLKAPTIDFTLRLG----HSSFYP
MMAR_5154|M.marinum_M EPGEGKP---TTMSGLHVVNNREFTVRLRAPTIDFMLSLG----HSSFYP
MUL_4240|M.ulcerans_Agy99 EPGEGKP---TTMSGLHVVNNREFTVRLRAPTIDFMLSLG----HSSFYP
MAV_0464|M.avium_104 --GQPQQ---TTMTGLRVVNDLEFTVRLKAPTVDFKLRLG----HSAFYP
MAB_0426|M.abscessus_ATCC_1997 DPAHKIAPRATQMRGLHVVDDVTFTVRLNTPFAIYPMTLG----YTAFLP
Mflv_2761|M.gilvum_PYR-GCK VEAPDPS---------------TVVIRVDRPTPNMLTNLG----GFKGMA
Mvan_3773|M.vanbaalenii_PYR-1 VDAPDPN---------------TVVIRVDRPTPNMLTNLG----GFKGMA
TH_4152|M.thermoresistible__bu VTAVDPL---------------TVRITVARPTPNLLTNLG----GFKGMA
MSMEG_1084|M.smegmatis_MC2_155 DSVQTVD-------------DHTLKMRLSQPFSEFLRMLAQGGNGSTAIM
. : : * *.
Mb3690c|M.bovis_AF2122/97 LPDSAFRDMAAFGRNPIGNGPYKLADGPAGPAWEHNVRIDLVPNPDYHGN
Rv3666c|M.tuberculosis_H37Rv LPDSAFRDMAAFGRNPIGNGPYKLADGPAGPAWEHNVRIDLVPNPDYHGN
MMAR_5154|M.marinum_M LPEAAFKDMAAFGRNPIGNGPYRLDSGGEEPAWEHNVKIDLVPNPDYRGN
MUL_4240|M.ulcerans_Agy99 LPEAAFKDMAAFGRNPIGNGPYRLDSGGEEPAWEHNVKIDLVPNPDYRGN
MAV_0464|M.avium_104 LPQAAFRDMAAFGRHPIGNGPYQLAGGPDGPAWEHNVRIDLRPNPDYHGN
MAB_0426|M.abscessus_ATCC_1997 LPKAFFRDPVKFGVHPIGNGPFKADG-----DWVRGVGFTLSRYDQYAGE
Mflv_2761|M.gilvum_PYR-GCK IVSRANVESGRIATHPVGTGPFSFLG------QKSGDSISLRANPDYWAG
Mvan_3773|M.vanbaalenii_PYR-1 IVSRANVESGRIATQPVGTGPFRFLG------QKSGDSISLAANPNYWDG
TH_4152|M.thermoresistible__bu IVQRANVETGRIATHPVGTGPFEFRG------ARSGDSITLVANDDHWAG
MSMEG_1084|M.smegmatis_MC2_155 SPTALQTYGEDVADHPVGTGPFKFKER------IRGERIDLVRNDDYWGK
.. :*:*.**: . : * ::
Mb3690c|M.bovis_AF2122/97 RKPRNKGLRFEFYANLDTAYADLLSGNLDVLDTIPPSALTVYQRDLGDHA
Rv3666c|M.tuberculosis_H37Rv RKPRNKGLRFEFYANLDTAYADLLSGNLDVLDTIPPSALTVYQRDLGDHA
MMAR_5154|M.marinum_M RKPRNKGLRFEFYANLETAYSDLLSGNLDVLDTIPSSALTVYGRDLGDNA
MUL_4240|M.ulcerans_Agy99 RKPRNKGLRFEFYANLETAYSDLLSGNLDVLDTIPSSALTVYGRDLGDNA
MAV_0464|M.avium_104 RKPRNKGLRFEFYANLDTAYADLLSGNLDVLDTIPPSALPVYRRDLGERV
MAB_0426|M.abscessus_ATCC_1997 KKAKAKGLIWRVYTEGLTAYTDMQAGALDIQLDLPDAAYENAKAEFGSAY
Mflv_2761|M.gilvum_PYR-GCK -PPGVAGVTFRFIPEPSTALSALQAGEVDWTDSVPPQRVSQLRDDESLQL
Mvan_3773|M.vanbaalenii_PYR-1 -PPGVSGVTYRFISEPSTALSALQAGEIDWTDSVPPQRVTQLRDDESLEL
TH_4152|M.thermoresistible__bu -PPRLNGVTFRFISEPATALSALQAGEIDWTDAIPTQRVTQLRNDDSLTL
MSMEG_1084|M.smegmatis_MC2_155 -VPYIDGVVFRPLPDPSARTAALRSGDVDMIAVPNPDSIDNLVS-EGYQL
. *: :. .: : : : :* :* .
Mb3690c|M.bovis_AF2122/97 TSGPAAINQTLDTPLRLPHFGGEEGRLRRLALSAAINRPQICQQIFAGTR
Rv3666c|M.tuberculosis_H37Rv TSGPAAINQTLDTPLRLPHFGGEEGRLRRLALSAAINRPQICQQIFAGTR
MMAR_5154|M.marinum_M TSGPAAINQTLDTPLRLAHFGGEEGRLRRLALSAAIDRPQICQQIFNGTR
MUL_4240|M.ulcerans_Agy99 TSGPAAINQTLDTPLRLAHFGGEEGRLRRLALSAAIDRPQICQQIFNGTR
MAV_0464|M.avium_104 TAGPAAINQSLDTPLRLPHFGGEEGRLRRLALSAAINRAQICRQIFADTR
MAB_0426|M.abscessus_ATCC_1997 LERPRPDITSLGFPMYDPRYRDVR---VRQAISMAIDREAITQVIFSGTR
Mflv_2761|M.gilvum_PYR-GCK TVTPSNDYWYLALNQARAPWNDVR---VRQAIAYAIDRDAIVQATSYGTA
Mvan_3773|M.vanbaalenii_PYR-1 AVTPSNDYWYLALNEAREPWNDVR---VRQAVAYAVDRDAIVQATSYGTA
TH_4152|M.thermoresistible__bu AVTPSNDYWYLALNHARAPWHDLR---VRRAIAFGIDREAIVTATGYGTA
MSMEG_1084|M.smegmatis_MC2_155 SEGTPPHTWYLSFNMKDR-YTSIP--EVRQAINLAVDREGMAKDMLRGSV
. * : . * *: .::* : .:
Mb3690c|M.bovis_AF2122/97 SPARDFTARSLPGFDPNLPGNEVLDYDPQRARRLWAQADAIS-PWSGRYA
Rv3666c|M.tuberculosis_H37Rv SPARDFTARSLPGFDPNLPGNEVLDYDPQRARRLWAQADAIS-PWSGRYA
MMAR_5154|M.marinum_M SAARDFTARSLPGFDPHIPGNEALDFNPQRARQLWAQANAIS-PWSGSYA
MUL_4240|M.ulcerans_Agy99 SAARDFTARSLPGFDPHIPGNEALDFNPQRARQLWAQANAIS-PWSGSYA
MAV_0464|M.avium_104 SPARDFTARSLPGFDPNIAGSDALDFDPERARRLWAQADAIS-AWSGSYP
MAB_0426|M.abscessus_ATCC_1997 TPATSYGSAVVYGYRKGACG-KLCELHVDEANKLLDEAHFDR-NKPIELW
Mflv_2761|M.gilvum_PYR-GCK AANQLAIPEGNPWFTPYDRYREDGEEGLETARDLLRQANAT----PGDLD
Mvan_3773|M.vanbaalenii_PYR-1 AVNQLAIPQGNPWFTPYDRYRDDGEQGLETARTLLREAGAQ----PRELD
TH_4152|M.thermoresistible__bu TANQLAIPPGDFWYTHYDRYRYD----LDRARALLDEARAAGVDPPRRLD
MSMEG_1084|M.smegmatis_MC2_155 TPAWGVQALSAGGYVE---RKDIYQRNLDKARQLLASVGLADGFQTTLIT
: . : : *. * .. .
Mb3690c|M.bovis_AF2122/97 IAYNADAGHRDWVDAVANSIKNVLGIDAVAAPQPTFAGFRTQIT-NRAID
Rv3666c|M.tuberculosis_H37Rv IAYNADAGHRDWVDAVANSIKNVLGIDAVAAPQPTFAGFRTQIT-NRAID
MMAR_5154|M.marinum_M IAYNADSGHQEWVDTVANSIKNVLGIEAMGAPQPTFAGLRTQIT-NRTID
MUL_4240|M.ulcerans_Agy99 IAYNADSGHQEWVDAVANSIKNVLGIEAMGAPQPTFAGLRTQIT-NRTID
MAV_0464|M.avium_104 IAYNADAGHQDWVDAVANGIKNVLGIDALGAPQPTFAGFRTQIT-NRSIG
MAB_0426|M.abscessus_ATCC_1997 YSS-SSTGALSWVQAIGNQLQSNLKVPYLLKSLP-WSQFLPLQD-GKGMT
Mflv_2761|M.gilvum_PYR-GCK MLVTTEYPETVTAAQIVADNLAPLGITVNIRTVDFATWLDEQ---NSGNF
Mvan_3773|M.vanbaalenii_PYR-1 MLVTTEYPETVTAAQIIADNLAPLGISVKIRTVDFATWLDEQ---NSGNF
TH_4152|M.thermoresistible__bu MLVTGDYPQTVTAAQIIADNVAPLGITVDIRTVDFATWLDEQ---NNGTF
MSMEG_1084|M.smegmatis_MC2_155 STDGSGQIMPAQMAEFIQQNLAEIGIKVNIQTQEWISYLGVWARGMQDGV
. : : . : :
Mb3690c|M.bovis_AF2122/97 SAFRAGWQGDYPSMIGFLAPLFTAG----AGSNDVGYINPEFDAALAAAE
Rv3666c|M.tuberculosis_H37Rv SAFRAGWRGDYPSMIEFLAPLFTAG----AGSNDVGYINPEFDAALAAAE
MMAR_5154|M.marinum_M TAFRAGWQGDFPSMIEFLAPLYGTG----AGSNDVGYSNQEFDDALAAAA
MUL_4240|M.ulcerans_Agy99 TAFRAGWQGDFPSMIEFLAPLYGTG----AGSNDVGYSNQEFDDALAAAA
MAV_0464|M.avium_104 SAFRSGWQGDYPSMIEFLAPLFATG----AGSNDVGYSSPRFDAALATAE
MAB_0426|M.abscessus_ATCC_1997 GPFRSGWVMDYPSIYNFLESLYGTVALPPNGSNYVFYSNPAFDELLRQGN
Mflv_2761|M.gilvum_PYR-GCK DMLMMGWLGNIDPDDFYYAQHHTDG-----TSNAQKFSNPEVDRLLDAGR
Mvan_3773|M.vanbaalenii_PYR-1 DMLMMGWLGNIDPDDFYYAQHHTDG-----TSNAQKFSDPEVDRLLDASR
TH_4152|M.thermoresistible__bu DMLMMGWLGNIDPDDYYYAQHHTDG-----ASNAQRFSDPEVDRLLDAAR
MSMEG_1084|M.smegmatis_MC2_155 GMAQMSWGMTSPYWLYIVTSSELQAP---NGPNVGYYSSPALDKAMNNAI
.* .* : . .* : .
Mb3690c|M.bovis_AF2122/97 AAPTLTESHELVNDAQRILFHDMPVVPLWDYISVVGWSSQVSNVTVTWNG
Rv3666c|M.tuberculosis_H37Rv AAPTLTESHELVNDAQRILFHDMPVVPLWDYISVVGWSSQVSNVTVTWNG
MMAR_5154|M.marinum_M AAPTLQEADRLANVAQRILFHDMPTIPLWDYIAVVGWSTEVSNVQVTWNG
MUL_4240|M.ulcerans_Agy99 AAPTLQEADRLANVAQRILFHDMPTIPLWDYIAVVGWSTEVSNVQVTWNG
MAV_0464|M.avium_104 AAPDLPQAAALANDAQRILFHDMPVVPLWNYISVVGWSGEVSHVTVTWNG
MAB_0426|M.abscessus_ATCC_1997 NEPTVELATKAYQKAEDLLFKDLPAAPLFYEVNQAVHSKRVRNVKIGIQD
Mflv_2761|M.gilvum_PYR-GCK VETDEQTRKAGYARAATLIADEVSYIYLYNPSVIQAWNPALSGYEARRDG
Mvan_3773|M.vanbaalenii_PYR-1 VETDEAARKEQYAGAATLIADKVSYIYLYNPSVIQAWNPALSGYEARRDG
TH_4152|M.thermoresistible__bu AEPDRDRRKALYDRAATLIADRVSYLFLYNPAVVQAWSPDLSGYRARRDA
MSMEG_1084|M.smegmatis_MC2_155 IALDPQEAEQWWRRANNIVSDEAALVPIVNDKAPYVLAPYVSGFVSASEE
* :: . . : : :
Mb3690c|M.bovis_AF2122/97 LPDYENIVKA----------
Rv3666c|M.tuberculosis_H37Rv LPDYENIVKA----------
MMAR_5154|M.marinum_M LPDYENLVKA----------
MUL_4240|M.ulcerans_Agy99 LPDYENLVKA----------
MAV_0464|M.avium_104 LPDYENIVKA----------
MAB_0426|M.abscessus_ATCC_1997 CIEYADVEVVQ---------
Mflv_2761|M.gilvum_PYR-GCK AVRFRSASLDSDGNV-----
Mvan_3773|M.vanbaalenii_PYR-1 AVRFRSATFGADGGA-----
TH_4152|M.thermoresistible__bu AVRFRDASLNRDGLNRDGPP
MSMEG_1084|M.smegmatis_MC2_155 WYDLTSVKLEQ---------
.