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VRVVIVDDDVLLREGLASLLDRAGIDVVGLAGDARQVLHLVREKNPDLAIVDIRMPPTFTDEGLGAAHAI RSDSPGTGILVLSAHVEVEDAMELLADERGVGYLLKTRVTAVAELIDAMHRIADGGSVVDPVVVTELIAA HRRNDPLTCLTARERDVLKLMAEGRSNTGIARRLWVAEGTVEKHIQRILTKLGLPEAADDHRRVRAVIAF LNTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4378 | - | - | 100% (214) | two-component system response regulator |
| M. smegmatis MC2 155 | MSMEG_0983 | - | 1e-79 | 68.69% (214) | two-component system response regulator |
| M. smegmatis MC2 155 | MSMEG_3447 | - | 1e-60 | 56.54% (214) | two-component system response regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0867c | narL | 1e-23 | 38.31% (201) | nitrate/nitrite response transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2280 | - | 9e-50 | 48.13% (214) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0844c | narL | 3e-24 | 38.81% (201) | nitrate/nitrite response transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01286 | - | 4e-11 | 34.75% (118) | putative two-component response regulatory protein |
| M. abscessus ATCC 19977 | MAB_4498c | - | 6e-67 | 57.94% (214) | two-component LuxR family response regulator |
| M. marinum M | MMAR_4782 | narL | 5e-25 | 38.81% (201) | nitrate/nitrite response regulator protein NarL |
| M. avium 104 | MAV_0872 | - | 1e-21 | 36.93% (176) | DNA-binding response regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_1532 | - | 8e-51 | 49.07% (214) | two-component system response regulator |
| M. ulcerans Agy99 | MUL_0351 | narL | 6e-25 | 38.81% (201) | nitrate/nitrite response regulator protein NarL |
| M. vanbaalenii PYR-1 | Mvan_2073 | - | 2e-76 | 65.42% (214) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4378|M.smegmatis_MC2_155 -------------MRVVIVDDDVLLREGLASLLDRAG-IDVVGLAGDARQ
Mvan_2073|M.vanbaalenii_PYR-1 ----------MSALKVVVADDDVLLREGLASLLERSG-FDVVGQAGDGEK
MAB_4498c|M.abscessus_ATCC_199 ----------MSAIRVLVADDDTLLREGVASVLEKAG-FEVVGRAGDATA
Mflv_2280|M.gilvum_PYR-GCK -------------MRIVIAEDSALLRAGIERILTDAG-HQVVAGVPDATD
TH_1532|M.thermoresistible__bu -------------MRIVIAEDSALLRAGIERILTDAG-HEVVAGVPDATD
Mb0867c|M.bovis_AF2122/97 -----MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
Rv0844c|M.tuberculosis_H37Rv -----MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
MMAR_4782|M.marinum_M -----MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
MUL_0351|M.ulcerans_Agy99 -----MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
MAV_0872|M.avium_104 --------------------------------------MNVVGEAEDGSA
MLBr_01286|M.leprae_Br4923 MTGPTTDADAATPHRVLIAEDEALIRLDLAEMLRDEG-YDIVGEAADGQE
::*. . *.
MSMEG_4378|M.smegmatis_MC2_155 VLHLVREKNPDLAIVDIRMPPTFTDEGLGAAHAIRSDSPGTGILVLSAHV
Mvan_2073|M.vanbaalenii_PYR-1 LLELVRTRQPALVLTDIRMPPTHTSEGLDAAKIIRQESPEVGIVVLSAHV
MAB_4498c|M.abscessus_ATCC_199 LLELVRTESPNLVVVDIRMPPTHTTEGLEAAQKIRGEHPGIGVLVLSAHV
Mflv_2280|M.gilvum_PYR-GCK LLRLVNDERPDLAILDVRMPPTFTDEGIRAAALLRSQNPESPVLVLSHYV
TH_1532|M.thermoresistible__bu LLRLVNELRPDLAIVDVRMPPTFTDEGIRAAALLRSQNPESPVLVLSHYV
Mb0867c|M.bovis_AF2122/97 ALELIKAHLPDVALLDYRMP---GMDGAQVPAAVRSYELPTRVLLISAHD
Rv0844c|M.tuberculosis_H37Rv ALELIKAHLPDVALLDYRMP---GMDGAQVAAAVRSYELPTRVLLISAHD
MMAR_4782|M.marinum_M ALELIKTHLPDVALLDYRMP---RMDGAQVAAAVRSNELPTRVLLISAHD
MUL_0351|M.ulcerans_Agy99 ALELIETHLPDVALLDYRMP---RMDGAQVAAAVRSNGLPTRVLLISAHD
MAV_0872|M.avium_104 ALELIKSHQPDVALLDYRMP---GMDGAQVAAAVRADGLATRVLLISAHD
MLBr_01286|M.leprae_Br4923 AVELAERHKPDLVIMDVKMP---RRDGIDAASEIASKRIAP-IVVLTAFS
:.* . * :.: * :** :* .. : ::::: .
MSMEG_4378|M.smegmatis_MC2_155 EVEDAMELLADE-RGVGYLLKTRVTAVAELIDAMHRIADGGSVVDPVVVT
Mvan_2073|M.vanbaalenii_PYR-1 DVDHAMELLAGG-HAIGYLLKTRVTDVADFVDTLQRIANGASVVDPALVA
MAB_4498c|M.abscessus_ATCC_199 EVEYAAELITSG-DGVGYLLKSRIGDVGEFADACTRVAGGGSIVDPELVR
Mflv_2280|M.gilvum_PYR-GCK EERYAADLIASDTRGFGYLLKDRVADVPAFLDAVEVVGAGGTVLDPEVVS
TH_1532|M.thermoresistible__bu EERYAADLIASDTKGFGYLLKDRVADVPAFLDAVEVVGGGGTVLDPEVVS
Mb0867c|M.bovis_AF2122/97 EPAIVYQALQQG--AAGFLLKD--STRTEIVKAVLDCAKGRDVVAPSLVG
Rv0844c|M.tuberculosis_H37Rv EPAIVYQALQQG--AAGFLLKD--STRTEIVKAVLDCAKGRDVVAPSLVG
MMAR_4782|M.marinum_M ESAIVYQALQQG--AAGFLLKD--STRTEIVKAVLDCAKGRDVVAPSLVG
MUL_0351|M.ulcerans_Agy99 ESAIVYQALQQG--AAGFLLKD--STRTEIVKAVLDCAKGRDVVAPSLVG
MAV_0872|M.avium_104 ESAIVYQALQQG--AAGFVLKD--STRSEIVKAVLDCAQGRDVVAPALVG
MLBr_01286|M.leprae_Br4923 QRDLVERARDAG--AMAYLVKP--FTISDLIPAIALAMSRFSELT-ALER
: . . .:::* : : : :
MSMEG_4378|M.smegmatis_MC2_155 ELIAAHRRNDP--LTCLTARERDVLKLMAEGRSNTGIARRLWVAEGTVEK
Mvan_2073|M.vanbaalenii_PYR-1 ELVSARKRDDP--LAALSAREHEVLTLMAEGLSNGGIGRRLWVTEGTVEK
MAB_4498c|M.abscessus_ATCC_199 ELLSARRKDDP--LSALSQRELEVLELMAQGLSNSGIAGRLWITESTVEK
Mflv_2280|M.gilvum_PYR-GCK QILARSHRRNV--LDALTPRENEVLQLMAEGKTNSAIASGLHMSVGSAEK
TH_1532|M.thermoresistible__bu QILVRSHRRSA--LDELTAREHDVLRLMAEGKTNSAIAGALHISIGSAEK
Mb0867c|M.bovis_AF2122/97 GLAGEIRQRAAPVAPVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKT
Rv0844c|M.tuberculosis_H37Rv GLAGEIRQRAAPVAPVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKT
MMAR_4782|M.marinum_M GLAGEIRQRAAPMAPVLSAREREVLHRIAKGQSIPAIAGELYVAPSTVKT
MUL_0351|M.ulcerans_Agy99 GLAGEIRQRAAPMAPVLSAREREVLHRIAKGQSIPAIAGELYVAPSTVKT
MAV_0872|M.avium_104 GLAAEIRQRAEPTGPVLSAREREVLHRIARGQSIPAIAGELYVAPSTVKT
MLBr_01286|M.leprae_Br4923 EVATLADRLETRKLVERAKGLLQVKQGMTEPEAFKWIQRAAMDRRTTMKR
: : : :* :: : * : :
MSMEG_4378|M.smegmatis_MC2_155 HIQRILTKLGLPEAADDHRRVRAVIAFLNTR
Mvan_2073|M.vanbaalenii_PYR-1 HVRSILTKLNLPETGDDHRRVRAVIMYLETR
MAB_4498c|M.abscessus_ATCC_199 HVHSVMRRLDLGHADEYHRRVLAVLAFLTHR
Mflv_2280|M.gilvum_PYR-GCK HIASIFTKLGLAPDDTENRRVLAVLRYLES-
TH_1532|M.thermoresistible__bu HIASIFTKLGLEPDESENRRVLAVLRYLES-
Mb0867c|M.bovis_AF2122/97 HVQRLYEKLGVSDRAAAVAEAMRQRLLD---
Rv0844c|M.tuberculosis_H37Rv HVQRLYEKLGVSDRAAAVAEAMRQRLLD---
MMAR_4782|M.marinum_M HVQRLYEKLGVSDRAAAVAEAMRQGLLD---
MUL_0351|M.ulcerans_Agy99 HVQRLYEKLGVSDRAAAVAEAMRQGLLD---
MAV_0872|M.avium_104 HVQRLYEKLGVSDRAAAVAEAMRQGLLS---
MLBr_01286|M.leprae_Br4923 VAEVVLETLDTPKDT----------------
: *.