For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SALKVVVADDDVLLREGLASLLERSGFDVVGQAGDGEKLLELVRTRQPALVLTDIRMPPTHTSEGLDAAK IIRQESPEVGIVVLSAHVDVDHAMELLAGGHAIGYLLKTRVTDVADFVDTLQRIANGASVVDPALVAELV SARKRDDPLAALSAREHEVLTLMAEGLSNGGIGRRLWVTEGTVEKHVRSILTKLNLPETGDDHRRVRAVI MYLETR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2073 | - | - | 100% (217) | two component LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0263 | - | 3e-48 | 48.36% (213) | two component LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4386 | - | 5e-44 | 43.13% (211) | two component LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0867c | narL | 2e-21 | 36.63% (202) | nitrate/nitrite response transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0968 | - | 3e-44 | 45.21% (219) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0844c | narL | 1e-21 | 36.68% (199) | nitrate/nitrite response transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01286 | - | 1e-12 | 37.14% (105) | putative two-component response regulatory protein |
| M. abscessus ATCC 19977 | MAB_4498c | - | 5e-74 | 61.29% (217) | two-component LuxR family response regulator |
| M. marinum M | MMAR_4782 | narL | 1e-22 | 37.19% (199) | nitrate/nitrite response regulator protein NarL |
| M. avium 104 | MAV_5280 | - | 2e-18 | 28.43% (204) | two-component system response regulator |
| M. smegmatis MC2 155 | MSMEG_0983 | - | 2e-93 | 79.26% (217) | two-component system response regulator |
| M. thermoresistible (build 8) | TH_1532 | - | 1e-44 | 42.06% (214) | two-component system response regulator |
| M. ulcerans Agy99 | MUL_0351 | narL | 1e-22 | 37.19% (199) | nitrate/nitrite response regulator protein NarL |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0867c|M.bovis_AF2122/97 -----MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
Rv0844c|M.tuberculosis_H37Rv -----MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
MMAR_4782|M.marinum_M -----MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
MUL_0351|M.ulcerans_Agy99 -----MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
Mvan_2073|M.vanbaalenii_PYR-1 ----------MSALKVVVADDDVLLREGLASLLERSG-FDVVGQAGDGEK
MSMEG_0983|M.smegmatis_MC2_155 ----------MSGLQVVVADDDVLLREGLSSLLDRSG-FDVVGQAADATE
MAB_4498c|M.abscessus_ATCC_199 ----------MSAIRVLVADDDTLLREGVASVLEKAG-FEVVGRAGDATA
Mflv_0968|M.gilvum_PYR-GCK ----------MTGLRVVLAEDAPLLRAGIVTVLESDG-HQVCAAVESADE
TH_1532|M.thermoresistible__bu -------------MRIVIAEDSALLRAGIERILTDAG-HEVVAGVPDATD
MAV_5280|M.avium_104 ------MTDPAPEITVLLVDDQDLVRSGLRRILRRKDGFVIVAECADGDE
MLBr_01286|M.leprae_Br4923 MTGPTTDADAATPHRVLIAEDEALIRLDLAEMLRDEG-YDIVGEAADGQE
::: :* *.* .: * . : . ..
Mb0867c|M.bovis_AF2122/97 ALELIKAHLPDVALLDYRMP---GMDGAQVPAAVRSYELPTRVLLISAHD
Rv0844c|M.tuberculosis_H37Rv ALELIKAHLPDVALLDYRMP---GMDGAQVAAAVRSYELPTRVLLISAHD
MMAR_4782|M.marinum_M ALELIKTHLPDVALLDYRMP---RMDGAQVAAAVRSNELPTRVLLISAHD
MUL_0351|M.ulcerans_Agy99 ALELIETHLPDVALLDYRMP---RMDGAQVAAAVRSNGLPTRVLLISAHD
Mvan_2073|M.vanbaalenii_PYR-1 LLELVRTRQPALVLTDIRMPPTHTSEGLDAAKIIRQESPEVGIVVLSAHV
MSMEG_0983|M.smegmatis_MC2_155 LLTLVREKTPQLAVVDIRMPPTNTTEGLDAAKVIRSEFPDTGILVLSAHV
MAB_4498c|M.abscessus_ATCC_199 LLELVRTESPNLVVVDIRMPPTHTTEGLEAAQKIRGEHPGIGVLVLSAHV
Mflv_0968|M.gilvum_PYR-GCK LRAAVRAHNPDLVVTDVRMPPTHTDEGIRVAIELRRATPGLPVVILSQYT
TH_1532|M.thermoresistible__bu LLRLVNELRPDLAIVDVRMPPTFTDEGIRAAALLRSQNPESPVLVLSHYV
MAV_5280|M.avium_104 VPAAVAAHRPDVVVMDLRMR---RVDGIEATRRLGGRPP---VLALTTFN
MLBr_01286|M.leprae_Br4923 AVELAERHKPDLVIMDVKMP---RRDGIDAASEIASKRIAP-IVVLTAFS
* :.: * :* :* .. : :: :: .
Mb0867c|M.bovis_AF2122/97 EPAIVYQALQ------QGAAGFLLKD--STRTEIVKAVLDCAKGRDVVAP
Rv0844c|M.tuberculosis_H37Rv EPAIVYQALQ------QGAAGFLLKD--STRTEIVKAVLDCAKGRDVVAP
MMAR_4782|M.marinum_M ESAIVYQALQ------QGAAGFLLKD--STRTEIVKAVLDCAKGRDVVAP
MUL_0351|M.ulcerans_Agy99 ESAIVYQALQ------QGAAGFLLKD--STRTEIVKAVLDCAKGRDVVAP
Mvan_2073|M.vanbaalenii_PYR-1 DVDHAMELLA-----GGHAIGYLLKTRVTDVADFVDTLQRIANGASVVDP
MSMEG_0983|M.smegmatis_MC2_155 EVEHATELLA-----SGHGIGYLLKSRVTDVSDFVETLERIAKGASVVDP
MAB_4498c|M.abscessus_ATCC_199 EVEYAAELIT-----SGDGVGYLLKSRIGDVGEFADACTRVAGGGSIVDP
Mflv_0968|M.gilvum_PYR-GCK SVGSLDQLLDRTEDAGRAGLGYLLKDRVAHVRHFLDAVRDIASGATIIDP
TH_1532|M.thermoresistible__bu EERYAADLIA----SDTKGFGYLLKDRVADVPAFLDAVEVVGGGGTVLDP
MAV_5280|M.avium_104 EDELLSGALR------AGAAGFVLKD--SSAEELIRAVRAVARGEGYLDP
MLBr_01286|M.leprae_Br4923 QRDLVERARD------AGAMAYLVKP--FTISDLIPAIALAMSRFSELT-
. . .:::* : : :
Mb0867c|M.bovis_AF2122/97 SLVGGLAGEIRQRAAP----VAPVLSAREREVLNRIACGQSIPAIAAELY
Rv0844c|M.tuberculosis_H37Rv SLVGGLAGEIRQRAAP----VAPVLSAREREVLNRIACGQSIPAIAAELY
MMAR_4782|M.marinum_M SLVGGLAGEIRQRAAP----MAPVLSAREREVLHRIAKGQSIPAIAGELY
MUL_0351|M.ulcerans_Agy99 SLVGGLAGEIRQRAAP----MAPVLSAREREVLHRIAKGQSIPAIAGELY
Mvan_2073|M.vanbaalenii_PYR-1 ALVAELVSARKRDDP------LAALSAREHEVLTLMAEGLSNGGIGRRLW
MSMEG_0983|M.smegmatis_MC2_155 ALVSELVSARRRDDP------LAALSAREQEVLNLMAEGRSNAGIARRLW
MAB_4498c|M.abscessus_ATCC_199 ELVRELLSARRKDDP------LSALSQRELEVLELMAQGLSNSGIAGRLW
Mflv_0968|M.gilvum_PYR-GCK DIVVALVGASRRRGV------LATLTPREQEVLGLMAQGLTNPQIAQRLV
TH_1532|M.thermoresistible__bu EVVSQILVRSHRRSA------LDELTAREHDVLRLMAEGKTNSAIAGALH
MAV_5280|M.avium_104 AVTSRVLTTYRKAAPGPHGAAIAELTTRERDVLTLIGKGLSNSEIADELC
MLBr_01286|M.leprae_Br4923 ALEREVATLADRLETR----KLVERAKGLLQVKQGMTEPEAFKWIQRAAM
: : : : :* : : *
Mb0867c|M.bovis_AF2122/97 VAPSTVKTHVQRLYEKLGVSDRAAAVAEAMRQRLLD---
Rv0844c|M.tuberculosis_H37Rv VAPSTVKTHVQRLYEKLGVSDRAAAVAEAMRQRLLD---
MMAR_4782|M.marinum_M VAPSTVKTHVQRLYEKLGVSDRAAAVAEAMRQGLLD---
MUL_0351|M.ulcerans_Agy99 VAPSTVKTHVQRLYEKLGVSDRAAAVAEAMRQGLLD---
Mvan_2073|M.vanbaalenii_PYR-1 VTEGTVEKHVRSILTKLNLPETGDDHRRVRAVIMYLETR
MSMEG_0983|M.smegmatis_MC2_155 VTEGTVEKHVRSILTKLNLTETADDHRRVRAVITYLESR
MAB_4498c|M.abscessus_ATCC_199 ITESTVEKHVHSVMRRLDLGHADEYHRRVLAVLAFLTHR
Mflv_0968|M.gilvum_PYR-GCK VSEAAVRKHVGNIFAKLPLSAD--GDRRVLAVLTYLNEH
TH_1532|M.thermoresistible__bu ISIGSAEKHIASIFTKLGLEPDESENRRVLAVLRYLES-
MAV_5280|M.avium_104 ISGVTVKSHIGRIFGKLDLRDRAAAIVYAYDNGIVAPR-
MLBr_01286|M.leprae_Br4923 DRRTTMKRVAEVVLETLDTPKDT----------------
: . : *