For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TGAAPVLGGTLHVPNPIPGVTGITYRGRVKKRVVVWGTGFVGSMVIAEIVGHPLFELVGVGVSNPDKVGR DVGEICGLGAPVGVTATDDVDALIALKPDALVHYGPTAAQADANIALITRFLRAGIDVCSTAMTPWVWPK MHLNPPNWIEPITEACEVGQSSCFTTGIDPGFANDLFPMTLMGLCSEVRRVRASELLDYTNYTGDYEFEM GIGKPPEHRPLLESPDILIFAWGATVPMIAHAAGVELDEITTTWDKWVTPDDRKTAKGVIGAGNVAAVRF TINGVYRGETRIQLEHVNRIGADAAPDWPTGNDNDVYRVDIEGTPSISQETAFRFTDGSGRDAAAAGCLA TGLRALNAVPAVNQHLPGWVTPLDLPLIPGLGTIR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4350 | dapB | - | 100% (386) | dihydrodipicolinate reductase |
| M. smegmatis MC2 155 | MSMEG_5586 | - | 7e-62 | 36.16% (354) | hypothetical protein MSMEG_5586 |
| M. smegmatis MC2 155 | MSMEG_0407 | - | 4e-49 | 33.61% (357) | hypothetical protein MSMEG_0407 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0949c | - | 9e-58 | 36.26% (353) | hypothetical protein Mb0949c |
| M. gilvum PYR-GCK | Mflv_2763 | - | 0.0 | 87.61% (355) | dihydrodipicolinate reductase |
| M. tuberculosis H37Rv | Rv0926c | - | 9e-58 | 36.26% (353) | hypothetical protein Rv0926c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0258c | - | 1e-101 | 52.49% (362) | putative dihydropicolinate reductase |
| M. marinum M | MMAR_3359 | - | 0.0 | 84.79% (355) | hypothetical protein MMAR_3359 |
| M. avium 104 | MAV_2176 | dapB | 0.0 | 87.89% (355) | dihydrodipicolinate reductase N-terminus domain-containing |
| M. thermoresistible (build 8) | TH_4586 | - | 3e-61 | 37.50% (360) | PUTATIVE dihydrodipicolinate reductase |
| M. ulcerans Agy99 | MUL_4353 | - | 7e-34 | 33.06% (366) | hypothetical protein MUL_4353 |
| M. vanbaalenii PYR-1 | Mvan_3771 | - | 0.0 | 87.04% (355) | dihydrodipicolinate reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0949c|M.bovis_AF2122/97 -----------------------------MAIPVVQLGTGNVGVHSLRAL
Rv0926c|M.tuberculosis_H37Rv -----------------------------MAIPVVQLGTGNVGVHSLRAL
TH_4586|M.thermoresistible__bu ------------------------------MRRVVQFSTGNVGRHSLRTL
MMAR_3359|M.marinum_M -------------------------MSQSGGKRVVVWGTGFVGRMVIPEI
MAV_2176|M.avium_104 -------------------MAAR--MSEHGSKRVVVWGTGFVGKMVIAEI
Mflv_2763|M.gilvum_PYR-GCK -------------------MVG------SDVKRVVIWGTGFVGRMVIAEV
Mvan_3771|M.vanbaalenii_PYR-1 -------------------MACGAASEMTDVKRVVIWGTGFVGRMVIPEV
MSMEG_4350|M.smegmatis_MC2_155 MTGAAPVLGGTLHVPNPIPGVTGITYRGRVKKRVVVWGTGFVGSMVIAEI
MAB_0258c|M.abscessus_ATCC_199 ---------------------------MSDKYPVIVWGTGVVGKLVIREL
MUL_4353|M.ulcerans_Agy99 -------------------------MSGPAKLRVIQWATGGVGKAAIECI
*: .** ** : :
Mb0949c|M.bovis_AF2122/97 IADPEFELTGVWVSSDAKAGKDAAELAGLADSTGVRASTDLNAVLATGPR
Rv0926c|M.tuberculosis_H37Rv IADPEFELTGVWVSSDAKAGKDAAELAGLADSTGVRASTDLNAVLATGPR
TH_4586|M.thermoresistible__bu IGRPDLELVGVHAAGPEKIGRDAAELCGLSEPTGVIATGDLDALLALQPD
MMAR_3359|M.marinum_M VKHPLFELVGVGVSNPDKVGRDVGEICGLSEPVGISATDDVDALIALRPD
MAV_2176|M.avium_104 VKHPLFELVGVGVSNPAKVGRDVADICGLPEPTGVIATDDVDALIALKPD
Mflv_2763|M.gilvum_PYR-GCK VGHPRFELVGVGVSNPDKVGRDVGDICGLGRDLGLTATDDVDALIDLKPD
Mvan_3771|M.vanbaalenii_PYR-1 VRHPQFELVGVGVSNPDKAGRDVGEICGMGRDIGLIATDDVDALIDLKPD
MSMEG_4350|M.smegmatis_MC2_155 VGHPLFELVGVGVSNPDKVGRDVGEICGLGAPVGVTATDDVDALIALKPD
MAB_0258c|M.abscessus_ATCC_199 LDHPVFELAAVLVHDPAKDGVDVGTLVGS-HPTGLAATTDIDAALGTEG-
MUL_4353|M.ulcerans_Agy99 LNHPQLELAGCWVHSAAKHGLDVGTIIGA-ARFGVTATNDVDELLALDAD
: * :**.. . . * * *.. : * *: *: *:: :
Mb0949c|M.bovis_AF2122/97 CAVYNAMADNRLPEALEDYRRILAAGINIVGSGPVFLQYP-WQVIPDEII
Rv0926c|M.tuberculosis_H37Rv CAVYNAMADNRLPEALEDYRRILAAGINIVGSGPVFLQYP-WQVIPDEII
TH_4586|M.thermoresistible__bu CVVYTALGETRPAEAIEQMTKILSAGVNVVGTSLVWLATP-RQAD-EWLR
MMAR_3359|M.marinum_M ALVHYGPTAMHAQDNISLITRFLRAGIDVCSTAMTPWIWPTMHLNPPQWI
MAV_2176|M.avium_104 ALVHYGPTAMHAKENIALITRFLRAGIDVCSTAMTPWVWPTMHLNPPNWI
Mflv_2763|M.gilvum_PYR-GCK ALVHYGPTAARADANIELITRFLRAGIDVCSTAMTPWIWPTMHLNPPNWI
Mvan_3771|M.vanbaalenii_PYR-1 ALVHYGPTAAHAEANIELITRFLRAGIDVCSTAMTPWIWPTMHLNPPNWI
MSMEG_4350|M.smegmatis_MC2_155 ALVHYGPTAAQADANIALITRFLRAGIDVCSTAMTPWVWPKMHLNPPNWI
MAB_0258c|M.abscessus_ATCC_199 TVAYFGPTAQYALENIDNMSRALRSGHNIVSTAMTPWVYP--QVCPPEML
MUL_4353|M.ulcerans_Agy99 CVMYSPQVAD-----EQDVKAILRSGKNVFTP--VGWVYP---DLSKPRV
: * :* :: . . *
Mb0949c|M.bovis_AF2122/97 KPLQDAARAGNSSLYVNGIDPGFANDLLPMALAGTCESIEQIRCMEIVDY
Rv0926c|M.tuberculosis_H37Rv KPLQDAARAGNSSLYVNGIDPGFANDLLPMALAGTCESIEQIRCMEIVDY
TH_4586|M.thermoresistible__bu APLEQACKAGNSSLFVSGIDPGYSADTAVHSALSLVTRARSVTVQEIFDY
MMAR_3359|M.marinum_M QPITEACTLGESSCFTTGIDPGFANDLFPMTLMGLCSEVQRVRASELLDY
MAV_2176|M.avium_104 APITEACELGESSCFTTGIDPGFANDLFPMTLMGLCSEVRRVRASELLDY
Mflv_2763|M.gilvum_PYR-GCK EPVTVACELGESSCFTTGIDPGFANDLFPMTLMGLCSEVRTVRASELLDY
Mvan_3771|M.vanbaalenii_PYR-1 EPITVACELGESSCFTTGIDPGFANDLFPMTLMGLCSEVRRVRASELLDY
MSMEG_4350|M.smegmatis_MC2_155 EPITEACEVGQSSCFTTGIDPGFANDLFPMTLMGLCSEVRRVRASELLDY
MAB_0258c|M.abscessus_ATCC_199 ADIQHACEAGQTSCFTTGIDPGFANDLFPMTLLGVGGRVDSVLVQELLDY
MUL_4353|M.ulcerans_Agy99 KAVADAAVAGGVTLHGSGIHPGGITERFPLMVSSLSSAITHVRAEEFSDI
: *. * : . .**.** : . : *: *
Mb0949c|M.bovis_AF2122/97 ATYDSAVVMFDVMGFGKPMDQIPMLLQPGVLSLAWGSVVRQLAAGLGISL
Rv0926c|M.tuberculosis_H37Rv ATYDSAVVMFDVMGFGKPMDQIPMLLQPGVLSLAWGSVVRQLAAGLGISL
TH_4586|M.thermoresistible__bu ANYDDWEFTGTTMGFGSAPDDEPMLLMPGVITAMFGGLVRNLADQLGVEL
MMAR_3359|M.marinum_M TNYEG--DYEKEMGIGREPEFSPMLENRDVLIFAWGATVPMIAHAAGIML
MAV_2176|M.avium_104 TNYEG--DYEVEMGIGREPEYSPMLENRDVLIFAWGATVPMIAHAAGIML
Mflv_2763|M.gilvum_PYR-GCK TNYEG--DYDREMGIGKPPEFTPMLENPDILVFAWGATVPMIAHAAGIML
Mvan_3771|M.vanbaalenii_PYR-1 TNYEG--DYDREMGIGRPPEYRPMLENPDILVFAWGATVPMIAHAAGIML
MSMEG_4350|M.smegmatis_MC2_155 TNYTG--DYEFEMGIGKPPEHRPLLESPDILIFAWGATVPMIAHAAGVEL
MAB_0258c|M.abscessus_ATCC_199 QYYNG--DFSTPMGLGAPMDQPAVLEIPEVLILAWGHTIPMIADAVGVKL
MUL_4353|M.ulcerans_Agy99 RTYNAPDVVRDIMGFGVPHAQAMQGPMAALLESGFKMSVRMIANHMGFHI
* **:* :: : : :* *. :
Mb0949c|M.bovis_AF2122/97 DGVEEMYVREPAPEAFNI----ASGHIPKGSAAALRFEVLGLVDGVPAVV
Rv0926c|M.tuberculosis_H37Rv DGVEEMYVREPAPEAFNI----ASGHIPKGSAAALRFEVLGLVDGVPAVV
TH_4586|M.thermoresistible__bu DDVRQRTERWFTTERIEC----RLTTVEPGGMAAVRFAVEGMRDDEPVIT
MMAR_3359|M.marinum_M DEITTTWEKWVTPTERKS----AKGLIKAGHVAAVRFTINGVYQGETRIQ
MAV_2176|M.avium_104 DEITTTWDKWVTPTERTT----AKGVIKPGHVAAVRFTINGVYRGETRIQ
Mflv_2763|M.gilvum_PYR-GCK DEITTTWDKWVTPDERRT----AKGVIAPGNVAAVRFTINGVYRGETRIQ
Mvan_3771|M.vanbaalenii_PYR-1 DEITTTWDKWVTPTERKT----AKGVIAPGHVAAVRFTVNGVYRGETRIQ
MSMEG_4350|M.smegmatis_MC2_155 DEITTTWDKWVTPDDRKT----AKGVIGAGNVAAVRFTINGVYRGETRIQ
MAB_0258c|M.abscessus_ATCC_199 DKIDTVYEKWATPTEISYGSAPNTGTIPAGHCAAVRFEIRGWVGGEPKIV
MUL_4353|M.ulcerans_Agy99 DPMIRATHEIAVATSDIAS---DVLPIAADTVAGRKFRWQTLADGKPVIT
* : . .. : . *. :* . . :
Mb0949c|M.bovis_AF2122/97 LEHVTRLR-ADLCPEWPQPAQ-PGGSYRIEISGEPCYAMDI-CLS---SR
Rv0926c|M.tuberculosis_H37Rv LEHVTRLR-ADLCPEWPQPAQ-PGGSYRIEISGEPCYAMDI-CLS---SR
TH_4586|M.thermoresistible__bu VEHVTRLT-PAAAPDWEFPPDNQPGVHRVVVEGEPRIELNT-HVS---QP
MMAR_3359|M.marinum_M LEHVNRIG-HDAAPDWPSGH--DDDVYRVDIEGTPSIFQET-AFRFTDGS
MAV_2176|M.avium_104 LEHVNRIG-LDAAPDWPSGH--DNDVYRVDIEGTPSIFQET-AFRFTDGS
Mflv_2763|M.gilvum_PYR-GCK LEHVNRIG-HDAAPDWPSGT--ESDVYRVDIEGTPSIFQET-AFRFTDGS
Mvan_3771|M.vanbaalenii_PYR-1 LEHVNRIG-SDAAPDWPSGN--ENDVYRVDIEGTPSIFQET-AFRFTDGS
MSMEG_4350|M.smegmatis_MC2_155 LEHVNRIG-ADAAPDWPTGN--DNDVYRVDIEGTPSISQET-AFRFTDGS
MAB_0258c|M.abscessus_ATCC_199 IEHVNRIT-NDTAPQWPRAQSVDNDAYRIEIKGSPNITQET-VFR-DERS
MUL_4353|M.ulcerans_Agy99 AAVNWLMGQADMHPDWSFGE--RGERFEIEITGNPSVSLVFKGLQPTSIT
: *:* ..: : * * .
Mb0949c|M.bovis_AF2122/97 HGDHNHAGLVATAMRIVNAIPAVVAAEPGIRTTLDLPLITGEGRYAAA--
Rv0926c|M.tuberculosis_H37Rv HGDHNHAGLVATAMRIVNAIPAVVAAEPGIRTTLDLPLITGEGRYAAA--
TH_4586|M.thermoresistible__bu FFDVTEAGCIATAARVINAIDWVCDAPPGLVEAADIPPTSLIRGLMW---
MMAR_3359|M.marinum_M GRDPATAGCLATGMRALNAVPAVNDLPPGWVTALDLPLIPGAGTIR----
MAV_2176|M.avium_104 GRDAAAAGCLATGLRALNAVPAVNELRPGWVTPLDLPLIPGTGTIR----
Mflv_2763|M.gilvum_PYR-GCK GRDAAAAGCLATGLRALNAVPAVNDLSPGWVTALDLPLIPGVGTIR----
Mvan_3771|M.vanbaalenii_PYR-1 GRDAAAAGCLATGLRALNAVPAVNDLSPGWVTALDLPLIPGLGTIR----
MSMEG_4350|M.smegmatis_MC2_155 GRDAAAAGCLATGLRALNAVPAVNQHLPGWVTPLDLPLIPGLGTIR----
MAB_0258c|M.abscessus_ATCC_199 G-DGAIGGCLATGMRAINAIPAVIDAKPGFLTPLDLPLIAGRGTIRI---
MUL_4353|M.ulcerans_Agy99 EGLQRNPGVVATANHCANAIPVVCAADPGIATYLDLPLFAGRPARASRGL
* :**. : **: * ** *:* .
Mb0949c|M.bovis_AF2122/97 --
Rv0926c|M.tuberculosis_H37Rv --
TH_4586|M.thermoresistible__bu --
MMAR_3359|M.marinum_M --
MAV_2176|M.avium_104 --
Mflv_2763|M.gilvum_PYR-GCK --
Mvan_3771|M.vanbaalenii_PYR-1 --
MSMEG_4350|M.smegmatis_MC2_155 --
MAB_0258c|M.abscessus_ATCC_199 --
MUL_4353|M.ulcerans_Agy99 ER