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MAIRVAAIGTGNVGRHALRQLITNPAYELTAVWVSSPEKAGKDAGDLAGLEVTTGIKATDSLDEVLATEP ECAVYTAMADNRLPDALEDYRRILAAGVNVVGSSAVFLQYPWQVLPEELVKPIEDAAHAGGASLFVNGID PGFANDLLPLALAGTCQQIEQIRCMEIVDYATYDSATVMLDVMGFGKSLDETPMLLQPGVLSLAWGSVVR QLAAGLGIELDAVTEEHTRVPAPEDFDIAAGHISEGTTAAMRFEVRGMVDGKPAVVLEHVTRLRDDLCPE WPQPAQEGGSYRVEVTGEPSYALDLCLSSPYGDHNHAGLVATAARVVNAIPAVFAAPPGIRTTLDMPLIT GKGLYAAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5586 | - | - | 100% (358) | hypothetical protein MSMEG_5586 |
| M. smegmatis MC2 155 | MSMEG_0407 | - | 7e-66 | 38.79% (348) | hypothetical protein MSMEG_0407 |
| M. smegmatis MC2 155 | MSMEG_4350 | dapB | 7e-62 | 36.16% (354) | dihydrodipicolinate reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0949c | - | 1e-160 | 75.35% (357) | hypothetical protein Mb0949c |
| M. gilvum PYR-GCK | Mflv_1824 | - | 1e-170 | 82.58% (356) | dihydrodipicolinate reductase |
| M. tuberculosis H37Rv | Rv0926c | - | 1e-160 | 75.35% (357) | hypothetical protein Rv0926c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4633 | - | 1e-142 | 69.14% (350) | hypothetical protein MAB_4633 |
| M. marinum M | MMAR_4582 | - | 1e-163 | 77.46% (355) | hypothetical protein MMAR_4582 |
| M. avium 104 | MAV_1045 | dapB | 1e-165 | 77.75% (355) | dihydrodipicolinate reductase N-terminus domain-containing |
| M. thermoresistible (build 8) | TH_0599 | - | 1e-163 | 78.59% (355) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4353 | - | 1e-41 | 32.78% (363) | hypothetical protein MUL_4353 |
| M. vanbaalenii PYR-1 | Mvan_4922 | - | 1e-168 | 81.18% (356) | dihydrodipicolinate reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1824|M.gilvum_PYR-GCK ----MAIKVAAVGTGNVGRHALAQLINDPRFELTAVWVSSEAKAGKDAAE
Mvan_4922|M.vanbaalenii_PYR-1 ----MAIKVAAIGTGNVGRHALTQLITDPRFELTAVWVSSESKAGKDAAE
MSMEG_5586|M.smegmatis_MC2_155 ----MAIRVAAIGTGNVGRHALRQLITNPAYELTAVWVSSPEKAGKDAGD
Mb0949c|M.bovis_AF2122/97 ----MAIPVVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAAE
Rv0926c|M.tuberculosis_H37Rv ----MAIPVVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAAE
MMAR_4582|M.marinum_M ----MAIPVVQLGTGNVGLHSLRALITNPEFELTGVWVSSDAKAGKDAAE
MAV_1045|M.avium_104 ----MPIPVVQLGTGNVGIHALRALITDPQFELTGVWVSSDAKAGKDAAE
TH_0599|M.thermoresistible__bu ----VTIRTAVVGTGNVGRHALAQVIADPRFDLTAVWVSSAAKAGLDAGE
MAB_4633|M.abscessus_ATCC_1997 ---MTKTRVAVWGTGNVGQHALAGVITDPSMELVGVWVSGSNKAGKDAGA
MUL_4353|M.ulcerans_Agy99 MSGPAKLRVIQWATGGVGKAAIECILNHPQLELAGCWVHSAAKHGLDVGT
. .**.** :: :: .* :*.. ** . * * *..
Mflv_1824|M.gilvum_PYR-GCK LAGLQDSTGIRATTDLDEVLATRPECVVYTALADNRLPDALEDYRRILAA
Mvan_4922|M.vanbaalenii_PYR-1 LVGLADSTGIRATTDLDAVLATRPQCAVYTALADNRLPEALEDYRRILAA
MSMEG_5586|M.smegmatis_MC2_155 LAGLEVTTGIKATDSLDEVLATEPECAVYTAMADNRLPDALEDYRRILAA
Mb0949c|M.bovis_AF2122/97 LAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILAA
Rv0926c|M.tuberculosis_H37Rv LAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILAA
MMAR_4582|M.marinum_M LAGFAESTGVKASTDLDAVLASGPQCAVYNAMADNRLPEALDDYRRVLAA
MAV_1045|M.avium_104 LAGLAQPTGVLASTDLDAVLATGPRCAVYNALADNRLPEALDDYRRVLAA
TH_0599|M.thermoresistible__bu LAGLDVSTGIRATTDLDELLATGPECVVYTAMADNRLNEALDDYRRILAA
MAB_4633|M.abscessus_ATCC_1997 LAGLDILTGITATTDAAQILALRPDCVVYTAMTDNRLMEALKDLTDLLSA
MUL_4353|M.ulcerans_Agy99 IIGAAR-FGVTATNDVDELLALDADCVMYSPQVAD-----EQDVKAILRS
: * *: *: . :** . *.:*.. . : .* :* :
Mflv_1824|M.gilvum_PYR-GCK GVNVVGSSAVFLQHPWQVLPAELISPIEDAAKAGNASLFVNGIDPGFAND
Mvan_4922|M.vanbaalenii_PYR-1 GVNVVGSSAVFLQHPWKVLPDELIAPIEDAAKAGSSTIFVNGIDPGFAND
MSMEG_5586|M.smegmatis_MC2_155 GVNVVGSSAVFLQYPWQVLPEELVKPIEDAAHAGGASLFVNGIDPGFAND
Mb0949c|M.bovis_AF2122/97 GINIVGSGPVFLQYPWQVIPDEIIKPLQDAARAGNSSLYVNGIDPGFAND
Rv0926c|M.tuberculosis_H37Rv GINIVGSGPVFLQYPWQVIPDEIIKPLQDAARAGNSSLYVNGIDPGFAND
MMAR_4582|M.marinum_M GVNIVGSGPVFLQYPWQVLPDELVKPLEDAAREGNSSLYVSGIDPGFAND
MAV_1045|M.avium_104 GINIVGSGPVFLQYPWQVIPDELIKPLEEAAQQGNSSLYVNGIDPGFAND
TH_0599|M.thermoresistible__bu GSNVVGSSAVFLQHPWQVLPAELIAPIEEAATAGNASLYVNGIDPGFAND
MAB_4633|M.abscessus_ATCC_1997 GINVAASAPVFLQYPWGVLPENMLTPIENAAREGNSSIFAGGIDPGFAND
MUL_4353|M.ulcerans_Agy99 GKNVFTP----VGWVYPDLSKPRVKAVADAAVAGGVTLHGSGIHPGGITE
* *: . : : :. : .: :** *. ::. .**.** .:
Mflv_1824|M.gilvum_PYR-GCK LLPMALAGTCQSIQQIRCMEIINYDTYDSAAVMFDVMGFGGSLDETPMLL
Mvan_4922|M.vanbaalenii_PYR-1 LLPMALAGTCQSIQQIRCMEIINYDTYDSAPVMFDVMGFGGSLDETPMLL
MSMEG_5586|M.smegmatis_MC2_155 LLPLALAGTCQQIEQIRCMEIVDYATYDSATVMLDVMGFGKSLDETPMLL
Mb0949c|M.bovis_AF2122/97 LLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFGKPMDQIPMLL
Rv0926c|M.tuberculosis_H37Rv LLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFGKPMDQIPMLL
MMAR_4582|M.marinum_M LLPMALAGTCQSIEQIRCMEIVDYATYDSAVVMFDVMGFGKPLDEIPMLL
MAV_1045|M.avium_104 LLPLALAGTCQSIQQIRCMEIVDYATYDSAAVMFDVMGFGKPLDDVPMLL
TH_0599|M.thermoresistible__bu QLPLALAGACQHIEQIRCLEIVDYATYDSATVLFDVMGFGKPLDEIPLLL
MAB_4633|M.abscessus_ATCC_1997 LLPLALMGTCQRIDQVRCIEIVDYATYDSATVMFDVMGFGKPMEETPMLL
MUL_4353|M.ulcerans_Agy99 RFPLMVSSLSSAITHVRAEEFSDIRTYNAPDVVRDIMGFGVPHAQAMQGP
:*: : . .. * ::*. *: : **::. *: *:**** . :
Mflv_1824|M.gilvum_PYR-GCK QPGVLSLAWGSVVRQLAAGLDIELD-EVTETHERVPAPESFDIAAGRIEE
Mvan_4922|M.vanbaalenii_PYR-1 QPGVLSLAWGSVVRQLAAGLGIELD-EVTETHLRVPAPEAFDIAAGRIEK
MSMEG_5586|M.smegmatis_MC2_155 QPGVLSLAWGSVVRQLAAGLGIELD-AVTEEHTRVPAPEDFDIAAGHISE
Mb0949c|M.bovis_AF2122/97 QPGVLSLAWGSVVRQLAAGLGISLD-GVEEMYVREPAPEAFNIASGHIPK
Rv0926c|M.tuberculosis_H37Rv QPGVLSLAWGSVVRQLAAGLGISLD-GVEEMYVREPAPEAFNIASGHIPK
MMAR_4582|M.marinum_M QPGVLSLAWGSVVRQLAAGLGLSLD-VVEEMYVREPAPHAFDIASGHIPQ
MAV_1045|M.avium_104 QPGVLSLAWGSVVRQLAAGLGVSLD-EVTQQHVRVPAPEDFDIASGHIAK
TH_0599|M.thermoresistible__bu QPGVLTMAWGSVVRQLAAGLGIELD-EVREQYVREPAPEDFDIAAGHIPQ
MAB_4633|M.abscessus_ATCC_1997 QPGVLSLAWGSVVRQLAAGLGVELD-EVTEVYEKLSAPEDFDISSGHIPA
MUL_4353|M.ulcerans_Agy99 MAALLESGFKMSVRMIANHMGFHIDPMIRATHEIAVATSDIASDVLPIAA
..:* .: ** :* :.. :* : : *. : *
Mflv_1824|M.gilvum_PYR-GCK GTTAAIRFEVRGMKDGNVAVILEHVTRL-RDDLCPDWPQPAQHGGSYRIE
Mvan_4922|M.vanbaalenii_PYR-1 GTTAAIRFEVRGMKDGEVAVVLEHVTRL-RDDLCPDWPQPAQHGGSYRIE
MSMEG_5586|M.smegmatis_MC2_155 GTTAAMRFEVRGMVDGKPAVVLEHVTRL-RDDLCPEWPQPAQEGGSYRVE
Mb0949c|M.bovis_AF2122/97 GSAAALRFEVLGLVDGVPAVVLEHVTRL-RADLCPEWPQPAQPGGSYRIE
Rv0926c|M.tuberculosis_H37Rv GSAAALRFEVLGLVDGVPAVVLEHVTRL-RADLCPEWPQPAQPGGSYRIE
MMAR_4582|M.marinum_M GSAAALRFEVLGLVDGAPVVVLEHVTRL-REDLCPDWPQPAQPGGSYRIE
MAV_1045|M.avium_104 GTAAALRFEVFGMVDGRPVVVLEHVTRL-REDLCPDWPQPAQHGGSYRIE
TH_0599|M.thermoresistible__bu GSAAALRFEVQGMVDGHPAVVLEHVTRL-RDDLRPDWPQPAQPGGSYRVE
MAB_4633|M.abscessus_ATCC_1997 GTMAALHFEVRGIKDGRAVTVLEHFTRL-REDLAPNWPQPAHEGGTYRVE
MUL_4353|M.ulcerans_Agy99 DTVAGRKFRWQTLADGKPVITAAVNWLMGQADMHPDWSFGER-GERFEIE
.: *. :*. : ** . : : *: *:*. : * :.:*
Mflv_1824|M.gilvum_PYR-GCK VTGEPSYAMDLC----LSSPNGDHNHAGLVATAARVVNAIPAVVDSSPGI
Mvan_4922|M.vanbaalenii_PYR-1 ITGEPSYALDLC----LSSPNGDHNHAGLVATAARVVNAIPAVIDAAPGI
MSMEG_5586|M.smegmatis_MC2_155 VTGEPSYALDLC----LSSPYGDHNHAGLVATAARVVNAIPAVFAAPPGI
Mb0949c|M.bovis_AF2122/97 ISGEPCYAMDIC----LSSRHGDHNHAGLVATAMRIVNAIPAVVAAEPGI
Rv0926c|M.tuberculosis_H37Rv ISGEPCYAMDIC----LSSRHGDHNHAGLVATAMRIVNAIPAVVAAEPGI
MMAR_4582|M.marinum_M ITGEPSYAMDLC----LSSRRGDHNHAGLVATAMRVVNAIPAVVAAPPGI
MAV_1045|M.avium_104 VTGEPSYAMDIC----LSSRKGDHNHAGLVATAMRVVNAIPAVVAAPPGI
TH_0599|M.thermoresistible__bu VTGEPCYTLDLR----LSSPHGDHNHAGLVATAARVVNAIPPVVAAPAGI
MAB_4633|M.abscessus_ATCC_1997 ITGEPSYLLDLG----SFSARGDHNYANLIATAMRVVNAVPAVVAAEAGI
MUL_4353|M.ulcerans_Agy99 ITGNPSVSLVFKGLQPTSITEGLQRNPGVVATANHCANAIPVVCAADPGI
::*:*. : : * :. ..::*** : .**:* * : .**
Mflv_1824|M.gilvum_PYR-GCK VTARELPPITGKGLYANP--------
Mvan_4922|M.vanbaalenii_PYR-1 VTARELPPITGEGLYAKP--------
MSMEG_5586|M.smegmatis_MC2_155 RTTLDMPLITGKGLYAAR--------
Mb0949c|M.bovis_AF2122/97 RTTLDLPLITGEGRYAAA--------
Rv0926c|M.tuberculosis_H37Rv RTTLDLPLITGEGRYAAA--------
MMAR_4582|M.marinum_M RTTLELPLVTGKGLYLPPAGAA----
MAV_1045|M.avium_104 VTTLDLPLITGRGLYRPE--------
TH_0599|M.thermoresistible__bu RTTLDLPWVSGTGRYLPPDRPEGTIR
MAB_4633|M.abscessus_ATCC_1997 RTTLDLPLITGKGRAV----------
MUL_4353|M.ulcerans_Agy99 ATYLDLPLFAGRPARASRGLER----
* ::* .:*