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VAARMSEHGSKRVVVWGTGFVGKMVIAEIVKHPLFELVGVGVSNPAKVGRDVADICGLPEPTGVIATDDV DALIALKPDALVHYGPTAMHAKENIALITRFLRAGIDVCSTAMTPWVWPTMHLNPPNWIAPITEACELGE SSCFTTGIDPGFANDLFPMTLMGLCSEVRRVRASELLDYTNYEGDYEVEMGIGREPEYSPMLENRDVLIF AWGATVPMIAHAAGIMLDEITTTWDKWVTPTERTTAKGVIKPGHVAAVRFTINGVYRGETRIQLEHVNRI GLDAAPDWPSGHDNDVYRVDIEGTPSIFQETAFRFTDGSGRDAAAAGCLATGLRALNAVPAVNELRPGWV TPLDLPLIPGTGTIR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2176 | dapB | - | 100% (365) | dihydrodipicolinate reductase N-terminus domain-containing protein |
| M. avium 104 | MAV_1045 | dapB | 4e-62 | 38.38% (357) | dihydrodipicolinate reductase N-terminus domain-containing |
| M. avium 104 | MAV_5137 | - | 2e-61 | 39.28% (359) | homoserine dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0949c | - | 1e-57 | 36.83% (353) | hypothetical protein Mb0949c |
| M. gilvum PYR-GCK | Mflv_2763 | - | 0.0 | 87.32% (355) | dihydrodipicolinate reductase |
| M. tuberculosis H37Rv | Rv0926c | - | 1e-57 | 36.83% (353) | hypothetical protein Rv0926c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0258c | - | 1e-103 | 53.48% (359) | putative dihydropicolinate reductase |
| M. marinum M | MMAR_3359 | - | 0.0 | 89.47% (361) | hypothetical protein MMAR_3359 |
| M. smegmatis MC2 155 | MSMEG_4350 | dapB | 0.0 | 87.89% (355) | dihydrodipicolinate reductase |
| M. thermoresistible (build 8) | TH_4586 | - | 5e-61 | 38.81% (353) | PUTATIVE dihydrodipicolinate reductase |
| M. ulcerans Agy99 | MUL_3685 | - | 2e-32 | 30.30% (363) | hypothetical protein MUL_3685 |
| M. vanbaalenii PYR-1 | Mvan_3771 | - | 0.0 | 88.45% (355) | dihydrodipicolinate reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0949c|M.bovis_AF2122/97 -----------------------------MAIPVVQLGTGNVGVHSLRAL
Rv0926c|M.tuberculosis_H37Rv -----------------------------MAIPVVQLGTGNVGVHSLRAL
TH_4586|M.thermoresistible__bu ------------------------------MRRVVQFSTGNVGRHSLRTL
MAV_2176|M.avium_104 -------------------MAAR--MSEHGSKRVVVWGTGFVGKMVIAEI
MMAR_3359|M.marinum_M -------------------------MSQSGGKRVVVWGTGFVGRMVIPEI
Mflv_2763|M.gilvum_PYR-GCK -------------------MVG------SDVKRVVIWGTGFVGRMVIAEV
Mvan_3771|M.vanbaalenii_PYR-1 -------------------MACGAASEMTDVKRVVIWGTGFVGRMVIPEV
MSMEG_4350|M.smegmatis_MC2_155 MTGAAPVLGGTLHVPNPIPGVTGITYRGRVKKRVVVWGTGFVGSMVIAEI
MAB_0258c|M.abscessus_ATCC_199 ---------------------------MSDKYPVIVWGTGVVGKLVIREL
MUL_3685|M.ulcerans_Agy99 -------------------------MSTARPLRVIQWTTGNIGRRSLHAI
*: ** :* : :
Mb0949c|M.bovis_AF2122/97 IADPEFELTGVWVSSDAKAGKDAAELAGLADSTGVRASTDLNAVLATGPR
Rv0926c|M.tuberculosis_H37Rv IADPEFELTGVWVSSDAKAGKDAAELAGLADSTGVRASTDLNAVLATGPR
TH_4586|M.thermoresistible__bu IGRPDLELVGVHAAGPEKIGRDAAELCGLSEPTGVIATGDLDALLALQPD
MAV_2176|M.avium_104 VKHPLFELVGVGVSNPAKVGRDVADICGLPEPTGVIATDDVDALIALKPD
MMAR_3359|M.marinum_M VKHPLFELVGVGVSNPDKVGRDVGEICGLSEPVGISATDDVDALIALRPD
Mflv_2763|M.gilvum_PYR-GCK VGHPRFELVGVGVSNPDKVGRDVGDICGLGRDLGLTATDDVDALIDLKPD
Mvan_3771|M.vanbaalenii_PYR-1 VRHPQFELVGVGVSNPDKAGRDVGEICGMGRDIGLIATDDVDALIDLKPD
MSMEG_4350|M.smegmatis_MC2_155 VGHPLFELVGVGVSNPDKVGRDVGEICGLGAPVGVTATDDVDALIALKPD
MAB_0258c|M.abscessus_ATCC_199 LDHPVFELAAVLVHDPAKDGVDVGTLVGS-HPTGLAATTDIDAALGTEG-
MUL_3685|M.ulcerans_Agy99 IGRPDLELVGVYAHGPDKVGVDAAELAGWPDPTGVRATSDIGALLALGAD
: * :**..* . . * * *.. : * *: *: *:.* :
Mb0949c|M.bovis_AF2122/97 CAVYNAMADNRLPEALEDYRRILAAGINIVGSGPVFLQYP-WQVIPDEII
Rv0926c|M.tuberculosis_H37Rv CAVYNAMADNRLPEALEDYRRILAAGINIVGSGPVFLQYP-WQVIPDEII
TH_4586|M.thermoresistible__bu CVVYTALGETRPAEAIEQMTKILSAGVNVVGTSLVWLATP-RQAD-EWLR
MAV_2176|M.avium_104 ALVHYGPTAMHAKENIALITRFLRAGIDVCSTAMTPWVWPTMHLNPPNWI
MMAR_3359|M.marinum_M ALVHYGPTAMHAQDNISLITRFLRAGIDVCSTAMTPWIWPTMHLNPPQWI
Mflv_2763|M.gilvum_PYR-GCK ALVHYGPTAARADANIELITRFLRAGIDVCSTAMTPWIWPTMHLNPPNWI
Mvan_3771|M.vanbaalenii_PYR-1 ALVHYGPTAAHAEANIELITRFLRAGIDVCSTAMTPWIWPTMHLNPPNWI
MSMEG_4350|M.smegmatis_MC2_155 ALVHYGPTAAQADANIALITRFLRAGIDVCSTAMTPWVWPKMHLNPPNWI
MAB_0258c|M.abscessus_ATCC_199 TVAYFGPTAQYALENIDNMSRALRSGHNIVSTAMTPWVYP--QVCPPEML
MUL_3685|M.ulcerans_Agy99 ACCYN-----PLWPNIDELVGLLESGVNVCTSA----AWITGGKQTPRDR
: : * :* :: :.
Mb0949c|M.bovis_AF2122/97 KPLQDAARAGNSSLYVNGIDPGFANDLLPMALAGTCESIEQIRCMEIVDY
Rv0926c|M.tuberculosis_H37Rv KPLQDAARAGNSSLYVNGIDPGFANDLLPMALAGTCESIEQIRCMEIVDY
TH_4586|M.thermoresistible__bu APLEQACKAGNSSLFVSGIDPGYSADTAVHSALSLVTRARSVTVQEIFDY
MAV_2176|M.avium_104 APITEACELGESSCFTTGIDPGFANDLFPMTLMGLCSEVRRVRASELLDY
MMAR_3359|M.marinum_M QPITEACTLGESSCFTTGIDPGFANDLFPMTLMGLCSEVQRVRASELLDY
Mflv_2763|M.gilvum_PYR-GCK EPVTVACELGESSCFTTGIDPGFANDLFPMTLMGLCSEVRTVRASELLDY
Mvan_3771|M.vanbaalenii_PYR-1 EPITVACELGESSCFTTGIDPGFANDLFPMTLMGLCSEVRRVRASELLDY
MSMEG_4350|M.smegmatis_MC2_155 EPITEACEVGQSSCFTTGIDPGFANDLFPMTLMGLCSEVRRVRASELLDY
MAB_0258c|M.abscessus_ATCC_199 ADIQHACEAGQTSCFTTGIDPGFANDLFPMTLLGVGGRVDSVLVQELLDY
MUL_3685|M.ulcerans_Agy99 ERILAACERGGATIFGSDAHPGMTN-MVGMVLSGSCERVDEIRITESVDC
: *. * :: : .. .** : . : * .*
Mb0949c|M.bovis_AF2122/97 ATYDSAVVMFDVMGFGKPMDQIPMLLQPGVLSLAWGSVVRQLAAGLGISL
Rv0926c|M.tuberculosis_H37Rv ATYDSAVVMFDVMGFGKPMDQIPMLLQPGVLSLAWGSVVRQLAAGLGISL
TH_4586|M.thermoresistible__bu ANYDDWEFTGTTMGFGSAPDDEPMLLMPGVITAMFGGLVRNLADQLGVEL
MAV_2176|M.avium_104 TNYEG--DYEVEMGIGREPEYSPMLENRDVLIFAWGATVPMIAHAAGIML
MMAR_3359|M.marinum_M TNYEG--DYEKEMGIGREPEFSPMLENRDVLIFAWGATVPMIAHAAGIML
Mflv_2763|M.gilvum_PYR-GCK TNYEG--DYDREMGIGKPPEFTPMLENPDILVFAWGATVPMIAHAAGIML
Mvan_3771|M.vanbaalenii_PYR-1 TNYEG--DYDREMGIGRPPEYRPMLENPDILVFAWGATVPMIAHAAGIML
MSMEG_4350|M.smegmatis_MC2_155 TNYTG--DYEFEMGIGKPPEHRPLLESPDILIFAWGATVPMIAHAAGVEL
MAB_0258c|M.abscessus_ATCC_199 QYYNG--DFSTPMGLGAPMDQPAVLEIPEVLILAWGHTIPMIADAVGVKL
MUL_3685|M.ulcerans_Agy99 STYES-AATQTAMGFSQHPDTPGLAESVRVESEVFAESAAMMADAIGATL
* . **:. : : : :. :* * *
Mb0949c|M.bovis_AF2122/97 DGVEEMYVREPAPEAFNI----ASGHIPKGSAAALRFEVLGLVDGVPAVV
Rv0926c|M.tuberculosis_H37Rv DGVEEMYVREPAPEAFNI----ASGHIPKGSAAALRFEVLGLVDGVPAVV
TH_4586|M.thermoresistible__bu DDVRQRTERWFTTERIEC----RLTTVEPGGMAAVRFAVEGMRDDEPVIT
MAV_2176|M.avium_104 DEITTTWDKWVTPTERTT----AKGVIKPGHVAAVRFTINGVYRGETRIQ
MMAR_3359|M.marinum_M DEITTTWEKWVTPTERKS----AKGLIKAGHVAAVRFTINGVYQGETRIQ
Mflv_2763|M.gilvum_PYR-GCK DEITTTWDKWVTPDERRT----AKGVIAPGNVAAVRFTINGVYRGETRIQ
Mvan_3771|M.vanbaalenii_PYR-1 DEITTTWDKWVTPTERKT----AKGVIAPGHVAAVRFTVNGVYRGETRIQ
MSMEG_4350|M.smegmatis_MC2_155 DEITTTWDKWVTPDDRKT----AKGVIGAGNVAAVRFTINGVYRGETRIQ
MAB_0258c|M.abscessus_ATCC_199 DKIDTVYEKWATPTEISYGSAPNTGTIPAGHCAAVRFEIRGWVGGEPKIV
MUL_3685|M.ulcerans_Agy99 DKMTFDVTFTAATADTDLG----FMKIPAGTVGSVYGYHRGWVGDRNVVS
* : :. : * .:: * . :
Mb0949c|M.bovis_AF2122/97 LEHVTRLRADLCPEWPQPAQ-PGGSYRIEISGEP-CYAMDICLS---SRH
Rv0926c|M.tuberculosis_H37Rv LEHVTRLRADLCPEWPQPAQ-PGGSYRIEISGEP-CYAMDICLS---SRH
TH_4586|M.thermoresistible__bu VEHVTRLTPAAAPDWEFPPDNQPGVHRVVVEGEP-RIELNTHVS---QPF
MAV_2176|M.avium_104 LEHVNRIGLDAAPDWPSGH--DNDVYRVDIEGTP-SIFQETAFRFTDGSG
MMAR_3359|M.marinum_M LEHVNRIGHDAAPDWPSGH--DDDVYRVDIEGTP-SIFQETAFRFTDGSG
Mflv_2763|M.gilvum_PYR-GCK LEHVNRIGHDAAPDWPSGT--ESDVYRVDIEGTP-SIFQETAFRFTDGSG
Mvan_3771|M.vanbaalenii_PYR-1 LEHVNRIGSDAAPDWPSGN--ENDVYRVDIEGTP-SIFQETAFRFTDGSG
MSMEG_4350|M.smegmatis_MC2_155 LEHVNRIGADAAPDWPTGN--DNDVYRVDIEGTP-SISQETAFRFTDGSG
MAB_0258c|M.abscessus_ATCC_199 IEHVNRITNDTAPQWPRAQSVDNDAYRIEIKGSP-NITQETVFR-DERSG
MUL_3685|M.ulcerans_Agy99 VGFNWTMGNHVVPPKPLKHG-----HVIQVFGLPNMRTVLHCLPPKDWTE
: . : * : : : * * .
Mb0949c|M.bovis_AF2122/97 GDHNHAGLVATAMRIVNAIPAVVAAEPGIRTTLDLPLITGEGRYAAA
Rv0926c|M.tuberculosis_H37Rv GDHNHAGLVATAMRIVNAIPAVVAAEPGIRTTLDLPLITGEGRYAAA
TH_4586|M.thermoresistible__bu FDVTEAGCIATAARVINAIDWVCDAPPGLVEAADIPPTSLIRGLMW-
MAV_2176|M.avium_104 RDAAAAGCLATGLRALNAVPAVNELRPGWVTPLDLPLIPGTGTIR--
MMAR_3359|M.marinum_M RDPATAGCLATGMRALNAVPAVNDLPPGWVTALDLPLIPGAGTIR--
Mflv_2763|M.gilvum_PYR-GCK RDAAAAGCLATGLRALNAVPAVNDLSPGWVTALDLPLIPGVGTIR--
Mvan_3771|M.vanbaalenii_PYR-1 RDAAAAGCLATGLRALNAVPAVNDLSPGWVTALDLPLIPGLGTIR--
MSMEG_4350|M.smegmatis_MC2_155 RDAAAAGCLATGLRALNAVPAVNQHLPGWVTPLDLPLIPGLGTIR--
MAB_0258c|M.abscessus_ATCC_199 -DGAIGGCLATGMRAINAIPAVIDAKPGFLTPLDLPLIAGRGTIRI-
MUL_3685|M.ulcerans_Agy99 SGFMGLGMIYTAMPVTNAVPAVVAAKPGIVTLADLPPITGRAAL---
. * : *. **: * ** *:* .