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MRRIAVWGTGNMGSTAIRSAVAFPGLELAAVITSSQDKVGRDAAMFAGLAEPTGVTATDDVDSALGACDA VAYMASGDIRPEEAIADIERCLRSGKHVVTPALYSLYDPRSAPEHWVERLTDAATAGNATLLVSGVDPGW ANDALAVTAAGLCTRIRSIRCQEIFDYSTYDQPYAVRVLCGFGTPMGPDDPVPMMLLPTIPTMVWGGNVR MIGRGLGLQIDDITEKVERLPLAQACENVLGRFETGTQGAFRVQVIGWADGVERVVIDHITRIDPACAPD WPQPDQGAGDHRVLIDGDPQLSIVVRADVPGGTRADGGNTTAANRLLGAIAWLAEQKPGIYDGLDVPLHP PLSAEAEATRWA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0407 | - | - | 100% (362) | hypothetical protein MSMEG_0407 |
| M. smegmatis MC2 155 | MSMEG_5586 | - | 8e-66 | 38.79% (348) | hypothetical protein MSMEG_5586 |
| M. smegmatis MC2 155 | MSMEG_4350 | dapB | 4e-49 | 33.61% (357) | dihydrodipicolinate reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0949c | - | 2e-64 | 38.78% (343) | hypothetical protein Mb0949c |
| M. gilvum PYR-GCK | Mflv_0408 | - | 1e-162 | 75.49% (359) | dihydrodipicolinate reductase |
| M. tuberculosis H37Rv | Rv0926c | - | 2e-64 | 38.78% (343) | hypothetical protein Rv0926c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4633 | - | 3e-58 | 36.21% (348) | hypothetical protein MAB_4633 |
| M. marinum M | MMAR_0386 | - | 7e-66 | 38.68% (349) | hypothetical protein MMAR_0386 |
| M. avium 104 | MAV_2461 | - | 5e-67 | 38.29% (350) | hypothetical protein MAV_2461 |
| M. thermoresistible (build 8) | TH_4586 | - | 5e-66 | 38.97% (349) | PUTATIVE dihydrodipicolinate reductase |
| M. ulcerans Agy99 | MUL_4353 | - | 3e-31 | 30.98% (368) | hypothetical protein MUL_4353 |
| M. vanbaalenii PYR-1 | Mvan_0266 | - | 1e-168 | 77.44% (359) | dihydrodipicolinate reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0408|M.gilvum_PYR-GCK --MQRAIGVAVWGTGNMGSTAIRSTAAFPGLALAGVITSSADKAGRDAAT
Mvan_0266|M.vanbaalenii_PYR-1 --MGATTAVAVWGTGNMGATAIRSVTAFPGLHLAGLITSSEDKAGRDAAS
MSMEG_0407|M.smegmatis_MC2_155 --MRR---IAVWGTGNMGSTAIRSAVAFPGLELAAVITSSQDKVGRDAAM
MAV_2461|M.avium_104 --MRR---VIQFSTGNVGRHSLRAIIGRPDLELVGVHAAGPEKIGRDAAQ
TH_4586|M.thermoresistible__bu --MRR---VVQFSTGNVGRHSLRTLIGRPDLELVGVHAAGPEKIGRDAAE
Mb0949c|M.bovis_AF2122/97 --MAIP--VVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAAE
Rv0926c|M.tuberculosis_H37Rv --MAIP--VVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAAE
MAB_4633|M.abscessus_ATCC_1997 -MTKTR--VAVWGTGNVGQHALAGVITDPSMELVGVWVSGSNKAGKDAGA
MMAR_0386|M.marinum_M --MAIR--VAHVGTGNVGRLALSELVTNPAFELTAVCVSTPEKVGRDAGD
MUL_4353|M.ulcerans_Agy99 MSGPAKLRVIQWATGGVGKAAIECILNHPQLELAGCWVHSAAKHGLDVGT
: .**.:* :: * : *.. . * * *..
Mflv_0408|M.gilvum_PYR-GCK FGGLEAPTGIAATTDVDAALA-ACDAVAYMASGDIRPDDALADIERCLRA
Mvan_0266|M.vanbaalenii_PYR-1 FARLDAPTGISASTDVDAVLA-DCHAVAYMASGDIRPDEAVADIERCLRA
MSMEG_0407|M.smegmatis_MC2_155 FAGLAEPTGVTATDDVDSALG-ACDAVAYMASGDIRPEEAIADIERCLRS
MAV_2461|M.avium_104 LCGLDEPTGIIATDDIDALVALNADCVVYTSQGETRPMEAIEQMSRFLAA
TH_4586|M.thermoresistible__bu LCGLSEPTGVIATGDLDALLALQPDCVVYTALGETRPAEAIEQMTKILSA
Mb0949c|M.bovis_AF2122/97 LAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILAA
Rv0926c|M.tuberculosis_H37Rv LAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILAA
MAB_4633|M.abscessus_ATCC_1997 LAGLDILTGITATTDAAQILALRPDCVVYTAMTDNRLMEALKDLTDLLSA
MMAR_0386|M.marinum_M LAGVGIETGIAAINDLDAVLATAPECVVYCAMGDTRLPDAMADVMRILAA
MUL_4353|M.ulcerans_Agy99 IIGAAR-FGVTATNDVDELLALDADCVMYSPQVADE-----QDVKAILRS
: *: * * :. .. * . . : * :
Mflv_0408|M.gilvum_PYR-GCK GRHVVTPSLYSLYDPA-SAPAEWIERLTAAAEEGRATLLVSGVDPGWGND
Mvan_0266|M.vanbaalenii_PYR-1 GVHVVTPSLYSLYDPR-SAPPEWVQRLTGAAEDGRAALLVSGVDPGWAND
MSMEG_0407|M.smegmatis_MC2_155 GKHVVTPALYSLYDPR-SAPEHWVERLTDAATAGNATLLVSGVDPGWAND
MAV_2461|M.avium_104 GTNVVGTSMVWLVAPR-HAEEWLREPLQRACEAGNTSLYVNGIDPGFSGD
TH_4586|M.thermoresistible__bu GVNVVGTSLVWLATPR-QADEWLRAPLEQACKAGNSSLFVSGIDPGYSAD
Mb0949c|M.bovis_AF2122/97 GINIVGSGPVFLQYPWQVIPDEIIKPLQDAARAGNSSLYVNGIDPGFAND
Rv0926c|M.tuberculosis_H37Rv GINIVGSGPVFLQYPWQVIPDEIIKPLQDAARAGNSSLYVNGIDPGFAND
MAB_4633|M.abscessus_ATCC_1997 GINVAASAPVFLQYPWGVLPENMLTPIENAAREGNSSIFAGGIDPGFAND
MMAR_0386|M.marinum_M GSNVVGSSPGLLQYPWGVIPDKYIARVQRAAEQGNSSIFITGVDPGFIND
MUL_4353|M.ulcerans_Agy99 GKNVFTP----VGWVYPDLSKPRVKAVADAAVAGGVTLHGSGIHPGGITE
* :: . : : *. * :: *:.** :
Mflv_0408|M.gilvum_PYR-GCK ALAVTAASLCTRINTITCQEIFDYSTYDQPFAVKVSCGFG---GSMDETP
Mvan_0266|M.vanbaalenii_PYR-1 ALAVTAAGLCTRINTITCQEIFDYSTYDQPYAVRVSCGFG---GPMDETP
MSMEG_0407|M.smegmatis_MC2_155 ALAVTAAGLCTRIRSIRCQEIFDYSTYDQPYAVRVLCGFGTPMGPDDPVP
MAV_2461|M.avium_104 TLVHAAVSLATRVSSITVQEIFDYGNYDDAEFTGAAMGFG--TAPDDDSP
TH_4586|M.thermoresistible__bu TAVHSALSLVTRARSVTVQEIFDYANYDDWEFTGTTMGFG--SAPDDE-P
Mb0949c|M.bovis_AF2122/97 LLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFG---KPMDQIP
Rv0926c|M.tuberculosis_H37Rv LLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFG---KPMDQIP
MAB_4633|M.abscessus_ATCC_1997 LLPLALMGTCQRIDQVRCIEIVDYATYDSATVMFDVMGFG---KPMEETP
MMAR_0386|M.marinum_M LLPFALAGTCQRIEQVRCMEIHDYASYDGAEVMH-YMGFG---RSLDEVP
MUL_4353|M.ulcerans_Agy99 RFPLMVSSLSSAITHVRAEEFSDIRTYNAPDVVRDIMGFG---VPHAQAM
. : *: * .*: *** .
Mflv_0408|M.gilvum_PYR-GCK MMLLPSIPTMVWGGNVRLVGRGLGIEID-EITEEVERLPLEETVETVMGT
Mvan_0266|M.vanbaalenii_PYR-1 MMLLPTIPTMVWGGNIRLIGRGLGLEID-EITEEVERLPLADSVDTVMGR
MSMEG_0407|M.smegmatis_MC2_155 MMLLPTIPTMVWGGNVRMIGRGLGLQID-DITEKVERLPLAQACENVLGR
MAV_2461|M.avium_104 MMFLPGVIVAMWGGQVRSLADHLGVELD-DVRQRIERWFTPERIDCTMMT
TH_4586|M.thermoresistible__bu MLLMPGVITAMFGGLVRNLADQLGVELD-DVRQRTERWFTTERIECRLTT
Mb0949c|M.bovis_AF2122/97 MLLQPGVLSLAWGSVVRQLAAGLGISLD-GVEEMYVREPAPEAFNIASGH
Rv0926c|M.tuberculosis_H37Rv MLLQPGVLSLAWGSVVRQLAAGLGISLD-GVEEMYVREPAPEAFNIASGH
MAB_4633|M.abscessus_ATCC_1997 MLLQPGVLSLAWGSVVRQLAAGLGVELD-EVTEVYEKLSAPEDFDISSGH
MMAR_0386|M.marinum_M MLLQPGVLGIAWGTAIRQLAAGLGIEVD-EITESYQREPAPEDFEIAVGP
MUL_4353|M.ulcerans_Agy99 QGPMAALLESGFKMSVRMIANHMGFHIDPMIRATHEIAVATSDIASDVLP
. : : :* :. :*. :* : .
Mflv_0408|M.gilvum_PYR-GCK FEKGTQGAFWLKVIGWSDGRQRIVIDHITRI-HPSCAPHWPQP-DQGDGE
Mvan_0266|M.vanbaalenii_PYR-1 FDEGTQGAFFLRVIGWSGGRQRVIVEHITRI-DPSCAPHWPQP-DQGVGD
MSMEG_0407|M.smegmatis_MC2_155 FETGTQGAFRVQVIGWADGVERVVIDHITRI-DPACAPDWPQP-DQGAGD
MAV_2461|M.avium_104 VQPGRMAAVRFATEGVRDGEPVITLEHVTRL-TRAAAPDWEYPPDGHTGV
TH_4586|M.thermoresistible__bu VEPGGMAAVRFAVEGMRDDEPVITVEHVTRL-TPAAAPDWEFPPDNQPGV
Mb0949c|M.bovis_AF2122/97 IPKGSAAALRFEVLGLVDGVPAVVLEHVTRL-RADLCPEWPQP-AQPGGS
Rv0926c|M.tuberculosis_H37Rv IPKGSAAALRFEVLGLVDGVPAVVLEHVTRL-RADLCPEWPQP-AQPGGS
MAB_4633|M.abscessus_ATCC_1997 IPAGTMAALHFEVRGIKDGRAVTVLEHFTRL-REDLAPNWPQP-AHEGGT
MMAR_0386|M.marinum_M VAKGTQAVLQFEIRGMVDGQAAIVIEHITRL-RPDLRPDWPQP-ASGGGS
MUL_4353|M.ulcerans_Agy99 IAADTVAGRKFRWQTLADGKPVITAAVNWLMGQADMHPDWSFG--ERGER
. . . . .. : *.*
Mflv_0408|M.gilvum_PYR-GCK HRVVVDGDPQLTITSR----ADVPGGTRADGGNTTAANRLLGALNWLVEQ
Mvan_0266|M.vanbaalenii_PYR-1 HRVIVDGDPQLTIVTR----ADVPGGTRADGGNTTAANRLLGAISWLAAQ
MSMEG_0407|M.smegmatis_MC2_155 HRVLIDGDPQLSIVVR----ADVPGGTRADGGNTTAANRLLGAIAWLAEQ
MAV_2461|M.avium_104 HRVVVAGEPRVEINTH----VSHPLFDSTDAGCISTAARVVNAIDWVCRA
TH_4586|M.thermoresistible__bu HRVVVEGEPRIELNTH----VSQPFFDVTEAGCIATAARVINAIDWVCDA
Mb0949c|M.bovis_AF2122/97 YRIEISGEPCYAMDIC----LSSRHGDHNHAGLVATAMRIVNAIPAVVAA
Rv0926c|M.tuberculosis_H37Rv YRIEISGEPCYAMDIC----LSSRHGDHNHAGLVATAMRIVNAIPAVVAA
MAB_4633|M.abscessus_ATCC_1997 YRVEITGEPSYLLDLG----SFSARGDHNYANLIATAMRVVNAVPAVVAA
MMAR_0386|M.marinum_M YRIEITGEPSYAVDIV----PSSRNGDHNHAAIVGAAGRIVNAIPAVLTA
MUL_4353|M.ulcerans_Agy99 FEIEITGNPSVSLVFKGLQPTSITEGLQRNPGVVATANHCANAIPVVCAA
..: : *:* : :* : .*: :
Mflv_0408|M.gilvum_PYR-GCK KPGIYDGLAVPLRSALPPEAEDARWA
Mvan_0266|M.vanbaalenii_PYR-1 KPGIYDGLDVPLHPPLAPELEATRWS
MSMEG_0407|M.smegmatis_MC2_155 KPGIYDGLDVPLHPPLSAEAEATRWA
MAV_2461|M.avium_104 PQGLIGVEDIPLAATMRGVLWQDR--
TH_4586|M.thermoresistible__bu PPGLVEAADIPPTSLIRGLMW-----
Mb0949c|M.bovis_AF2122/97 EPGIRTTLDLPLITGEGRYAAA----
Rv0926c|M.tuberculosis_H37Rv EPGIRTTLDLPLITGEGRYAAA----
MAB_4633|M.abscessus_ATCC_1997 EAGIRTTLDLPLITGKGRAV------
MMAR_0386|M.marinum_M TPGIRTTLDLPLITGKGLYTPMVSN-
MUL_4353|M.ulcerans_Agy99 DPGIATYLDLPLFAGRPARASRGLER
*: :* .