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M. ulcerans Agy99 MUL_4353 (-)

annotation: hypothetical protein MUL_4353
coordinates: 4830507 - 4831592
length: 361

MSGPAKLRVIQWATGGVGKAAIECILNHPQLELAGCWVHSAAKHGLDVGTIIGAARFGVTATNDVDELLA
LDADCVMYSPQVADEQDVKAILRSGKNVFTPVGWVYPDLSKPRVKAVADAAVAGGVTLHGSGIHPGGITE
RFPLMVSSLSSAITHVRAEEFSDIRTYNAPDVVRDIMGFGVPHAQAMQGPMAALLESGFKMSVRMIANHM
GFHIDPMIRATHEIAVATSDIASDVLPIAADTVAGRKFRWQTLADGKPVITAAVNWLMGQADMHPDWSFG
ERGERFEIEITGNPSVSLVFKGLQPTSITEGLQRNPGVVATANHCANAIPVVCAADPGIATYLDLPLFAG
RPARASRGLER
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4353--100% (361)hypothetical protein MUL_4353
M. ulcerans Agy99MUL_3685-2e-3731.84% (358) hypothetical protein MUL_3685
M. ulcerans Agy99MUL_2162-2e-2325.87% (344) hypothetical protein MUL_2162

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1088-1e-10954.18% (347) hypothetical protein Mb1088
M. gilvum PYR-GCKMflv_2027-1e-11456.21% (354) dihydrodipicolinate reductase
M. tuberculosis H37RvRv1059-1e-10954.18% (347) hypothetical protein Rv1059
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4633-4e-4031.28% (358) hypothetical protein MAB_4633
M. marinum MMMAR_5280-0.096.40% (361) hypothetical protein MMAR_5280
M. avium 104MAV_0353-1e-15474.22% (353) hypothetical protein MAV_0353
M. smegmatis MC2 155MSMEG_5286dapB1e-10854.47% (347) dihydrodipicolinate reductase N-terminus domain-containing
M. thermoresistible (build 8)TH_1493-1e-10954.34% (346) CONSERVED HYPOTHETICAL PROTEIN
M. vanbaalenii PYR-1Mvan_4692-1e-11455.77% (355) dihydrodipicolinate reductase

CLUSTAL 2.0.9 multiple sequence alignment


MUL_4353|M.ulcerans_Agy99           MSGPAKLRVIQWATGGVGKAAIECILNHPQLELAGCWVHSAAKHGLDVGT
MMAR_5280|M.marinum_M               MSGPAKLRVIQWATGGVGKAAIECILNHPQLELAGCWVHSAAKHGLDVGT
MAV_0353|M.avium_104                MSSPSKLRVIQWASGGVGKAAIQCVLNHPRLELAGCWVHSAEKNGVDVGR
Mflv_2027|M.gilvum_PYR-GCK          ----MALRVVQWATGGVGIAAIHGVLAHPELELVGCWVHSKAKAGRDVGD
Mvan_4692|M.vanbaalenii_PYR-1       ----MTLRVVQWATGGVGVAAIKGVLEHPELELVGCWVHSPGKAGRDVGE
MSMEG_5286|M.smegmatis_MC2_155      ----MALRVVQWATGGVGMAAIKGVLEHPALELVGCWVHSEGKAGRDVGE
TH_1493|M.thermoresistible__bu      ----MTFRVVQWATGGVGIAAIKGVLEHPELELVGCWVHSPDKAGRDVGE
Mb1088|M.bovis_AF2122/97            --MTMSLRVIQWATGSVGVAAIKGVLQHPELELVGCWVHSAAKSGKDVGE
Rv1059|M.tuberculosis_H37Rv         --MTMSLRVIQWATGSVGVAAIKGVLQHPELELVGCWVHSAAKSGKDVGE
MAB_4633|M.abscessus_ATCC_1997      ---MTKTRVAVWGTGNVGQHALAGVITDPSMELVGVWVSGSNKAGKDAGA
                                           **  *.:*.**  *:  :: .* :**.* ** .  * * *.* 

MUL_4353|M.ulcerans_Agy99           IIGAARFG-VTATNDVDELLALDADCVMYSPQVAD-----EQDVKAILRS
MMAR_5280|M.marinum_M               IIGAARLG-VTATNDVDELLALDADCVMYSPLVAD-----EQDVKAILRS
MAV_0353|M.avium_104                IIGTQELG-VTASTSVDEVLALDADCVVYSPLIPN-----DDEVIAILRS
Mflv_2027|M.gilvum_PYR-GCK          IVGTAPLG-VVATDSIDEILSLDADAVIYSPLIAD-----TEEVVALLKS
Mvan_4692|M.vanbaalenii_PYR-1       IVGLDPLG-VTATDSIDDILALEADAVIYSPLIAN-----PDEVAALLRS
MSMEG_5286|M.smegmatis_MC2_155      IIGTEPLG-VETTRDIDDILGLDADAVIYAPLLPN-----PEEVAALLRS
TH_1493|M.thermoresistible__bu      IIGAEPLG-ITATNSIDDILALDADAVIYAPLLPD-----PDEVAALLRS
Mb1088|M.bovis_AF2122/97            IIGSPPLG-VIATNSIDDVLALDADAVIYAPLLPS-----VDEVAALLRS
Rv1059|M.tuberculosis_H37Rv         IIGSPPLG-VIATNSIDDVLALDADAVIYAPLLPS-----VDEVAALLRS
MAB_4633|M.abscessus_ATCC_1997      LAGLDILTGITATTDAAQILALRPDCVVYTAMTDNRLMEALKDLTDLLSA
                                    : *   :  : :: .  ::*.* .*.*:*:.   .      .::  :* :

MUL_4353|M.ulcerans_Agy99           GKNVFT--PVGWVYPD--LSKPRVKAVADAAVAGGVTLHGSGIHPGGITE
MMAR_5280|M.marinum_M               GKNVVT--PVGWVYPD--LSKPRVKAVADAAVAGGVTLHGSGIHPGGITE
MAV_0353|M.avium_104                GKNVVT--PVGWVYPD--PGNPRHRAVADAALESGVTLHGSGIHPGGITE
Mflv_2027|M.gilvum_PYR-GCK          GKNVVT--PVGWLYP----SERSGAPLREAALAGDATLHGTGIAPGGISE
Mvan_4692|M.vanbaalenii_PYR-1       GKNVVT--PVGWLYP----SERSGASMREAALAGNATLHGTGIAPGGISE
MSMEG_5286|M.smegmatis_MC2_155      GKNVVT--PVGWVYP----SERQGAPLREAALAGNATLHGTGIAPGGISE
TH_1493|M.thermoresistible__bu      GKNVVT--PLGWFYP----TEKQAAPLRAAALEGGATLHGTGIAPGGISE
Mb1088|M.bovis_AF2122/97            GKNVVT--PLGWFYP----SEKEAAPLEVAAQAGNATLHGAGIGPGAVTE
Rv1059|M.tuberculosis_H37Rv         GKNVVT--PLGWFYP----SEKEAAPLEVAAQAGNATLHGAGIGPGAVTE
MAB_4633|M.abscessus_ATCC_1997      GINVAASAPVFLQYPWGVLPENMLTPIENAAREGNSSIFAGGIDPGFAND
                                    * ** :  *:   **     :    .:  **  .. ::.. ** **  .:

MUL_4353|M.ulcerans_Agy99           RFPLMVSSLSSAITHVRAEEFSDIRTYNAPDVVRDIMGFGVPHAQAMQGP
MMAR_5280|M.marinum_M               RFPLMVSSLSSAITHVRAEEFSDIRTYNAPDVVRDIMGFGVPPAQAMQGP
MAV_0353|M.avium_104                RFPLMVSSLSSAVTHVRAEEFSDIRTYNAPDVVRHIMGFGGTPEEATGGP
Mflv_2027|M.gilvum_PYR-GCK          KFPLMLSAMSTGVTFVRAEEYSDLRTYEAPDVLRHVMGFGETPDKALTGP
Mvan_4692|M.vanbaalenii_PYR-1       KFPLMLSAMSTGVTFVRAEEFSDLRTYEAPDVLRHVMGFGETPDKALTGP
MSMEG_5286|M.smegmatis_MC2_155      KFPLLFSVFSTGVTFVRAEEFSDLRTYDAPDVLRHVMGFGEVPDKALSGP
TH_1493|M.thermoresistible__bu      KLPLMFSALATGVTFVRAEEFSDLRTYDAPDVVRHVMGFGDTPEKALSGP
Mb1088|M.bovis_AF2122/97            LFPLLLSVMSTGVTFVRSEEFSDLRSYGAPDVLRYVMGFGGTPDSALTGP
Rv1059|M.tuberculosis_H37Rv         LFPLLLSVMSTGVTFVRSEEFSDLRSYGAPDVLRYVMGFGGTPDSALTGP
MAB_4633|M.abscessus_ATCC_1997      LLPLALMGTCQRIDQVRCIEIVDYATYDSATVMFDVMGFGKPMEETPMLL
                                     :** .   .  :  **. *  *  :* :. *:  :****    .:    

MUL_4353|M.ulcerans_Agy99           MAALLESGFKMSVRMIANHMGFHIDPMIRATHEIAVATSDIASDVLPIAA
MMAR_5280|M.marinum_M               MAALLESGFKMSVRMIADHMGFHIDPTIRATHEIAVATSDIASDVLPIAA
MAV_0353|M.avium_104                MAGLLDGGFKQSVRMIADHMGFRIDPNIRTIQDVAVATADIDYDPFPITA
Mflv_2027|M.gilvum_PYR-GCK          MQKMLDSGFIQAVRMVVDQLGFAADPKVRATQEIAVATAPIDSPMGQILP
Mvan_4692|M.vanbaalenii_PYR-1       MQKMLDTGFIQAVRMCVDQLGFAADPKVLATQEIAVATARIDSPMGPIEP
MSMEG_5286|M.smegmatis_MC2_155      MQKLLDGGFMQAVKMCVDQFGFAADPKIRSRQEIAVATAPIDSPLGAIQP
TH_1493|M.thermoresistible__bu      MQKLLDGGFIQAVRMCVDKIGFAADPQVRSRQEIAVATAPIESPIGVIEP
Mb1088|M.bovis_AF2122/97            MQKILDGGFLQSVRLCVDRLGFAADPQIRTSQEVAVATAPIDSPIGVIEP
Rv1059|M.tuberculosis_H37Rv         MQKILDGGFLQSVRLCVDRLGFAADPQIRTSQEVAVATAPIDSPIGVIEP
MAB_4633|M.abscessus_ATCC_1997      QPGVLSLAWGSVVRQLAAGLGVELD-EVTEVYEKLSAPEDFDISSGHIPA
                                       :*. .:   *:  .  :*.  *  :    :   *.  :      * .

MUL_4353|M.ulcerans_Agy99           DTVAGRKFRWQTLADGKPVITAAVNWLMGQADMHPDWSFGE-RGERFEIE
MMAR_5280|M.marinum_M               GTVAGRKFRWQALADGKPVITAAVNWLMGQADMDPDWSFGE-RGERFEIE
MAV_0353|M.avium_104                GTVAARRFRWQALVDGEPVITAAVNWLMGEQNLDPAWDFGG-RGERFEVE
Mflv_2027|M.gilvum_PYR-GCK          GQVAGRKFHWEALVGGQPVVRVTVNWLMGEENLEPAWSFGP-EGQRYEME
Mvan_4692|M.vanbaalenii_PYR-1       GQVAGRKFHWEALVDGEPVVRVTVNWLMGEENLDPAWSFGP-EGQRYEME
MSMEG_5286|M.smegmatis_MC2_155      GQVAGRRFHWEALRGEQVVVRVTVNWLMGEENLDPPWTFGP-QGQRYEMQ
TH_1493|M.thermoresistible__bu      GQVAGRRFHWEALAGDEVVVRVTVNWLMGEEDLDPPWDFGP-AGQRYEIE
Mb1088|M.bovis_AF2122/97            GQVAGRRFHWEALVEDTVVVQIAVNWLMGSENLDPPWSFGP-AGERYEIE
Rv1059|M.tuberculosis_H37Rv         GQVAGRRFHWEALVEDTVVVQIAVNWLMGSENLDPPWSFGP-AGERYEIE
MAB_4633|M.abscessus_ATCC_1997      GTMAALHFEVRGIKDGR-AVTVLEHFTRLREDLAPNWPQPAHEGGTYRVE
                                    . :*. :*. . :     .:    ::     :: * *      *  :.::

MUL_4353|M.ulcerans_Agy99           ITGNPSVSLVFKGLQPTSITEGLQRNPGVVATANHCANAIPVVCAADPGI
MMAR_5280|M.marinum_M               VTGDPSVSLVFKGLQPTSIAEGLQRNPGVVATANHCVNAIPVVCAADPGI
MAV_0353|M.avium_104                ITGDPDVSLTFKGLQPETIAEGLVKNPGVVVTANHCVNAIPDVCAAAPGI
Mflv_2027|M.gilvum_PYR-GCK          VRGNPDFTVSVKGFQSDIGGEGPE--YGVVGTAAHCVNSVPAVCAAAPGI
Mvan_4692|M.vanbaalenii_PYR-1       VRGNPDFTVSVKGFQSEVGGEGPE--YGVVGTAAHCVNSVPAVCAAPPGI
MSMEG_5286|M.smegmatis_MC2_155      VCGNPDFDVVIKGFQGEVGETGPE--PGVVATAAHCVNSIPAVCAAEPGI
TH_1493|M.thermoresistible__bu      VRGNPDFTVTINGFQSEPGDHGPE--AGIVATAAHCVNSVPAVCAADPGL
Mb1088|M.bovis_AF2122/97            VRGSPDTCVTIKGWQPQTVAAGLKSNPGIVATAAHCVNAIPATCAAPAGI
Rv1059|M.tuberculosis_H37Rv         VRGSPDTCVTIKGWQPQTVAAGLKSNPGIVATAAHCVNAIPATCAAPAGI
MAB_4633|M.abscessus_ATCC_1997      ITGEPSYLLDLGSFS----ARGDHNYANLIATAMRVVNAVPAVVAAEAGI
                                    : *.*.  : . . .      *     .:: ** : .*::* . ** .*:

MUL_4353|M.ulcerans_Agy99           ATYLDLPLFAGRPARASRGLER
MMAR_5280|M.marinum_M               ATYLDLPLFAGRPARASRGLER
MAV_0353|M.avium_104                KTYLDLPLFAGRPAPGLATS--
Mflv_2027|M.gilvum_PYR-GCK          ATYLDLPLISGKAAPDRARTGS
Mvan_4692|M.vanbaalenii_PYR-1       ATYLDLPLISGKAAPAKARAGI
MSMEG_5286|M.smegmatis_MC2_155      ATYLDLPLFSAKAAPHLR----
TH_1493|M.thermoresistible__bu      LTYLDMPLISGRAAPRLT----
Mb1088|M.bovis_AF2122/97            QSFFDLPLITGRAAPGLAR---
Rv1059|M.tuberculosis_H37Rv         QSFFDLPLITGRAAPGLAR---
MAB_4633|M.abscessus_ATCC_1997      RTTLDLPLITGKGRAV------
                                     : :*:**::.: