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RIDNVHSSAASARDATEFIATALPFVEAIERGARRLTTNRYDAEDLVQETLLKAYNGFHTFEGGTNMQAW LFRIMRNTWISNFRAQQRNPVEQLCEDFTDAQLSAGLRHGADGARSAENEALAHLPDDAVLEALRAIPQA NRMVVYYADVEGYPYREIATLMDTPIGTVMSRLARGRARLRVLLADHQAALPAGRAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0573 | - | - | 100% (198) | putative ECF sigma factor RpoE1 |
| M. smegmatis MC2 155 | MSMEG_1914 | - | 3e-49 | 50.53% (190) | RNA polymerase sigma-70 factor, family protein |
| M. smegmatis MC2 155 | MSMEG_1690 | - | 7e-45 | 51.11% (180) | putative ECF sigma factor RpoE1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3250c | sigH | 4e-51 | 56.80% (169) | RNA polymerase sigma factor RpoE |
| M. gilvum PYR-GCK | Mflv_4689 | - | 4e-51 | 53.51% (185) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv3223c | sigH | 4e-51 | 56.80% (169) | RNA polymerase sigma factor RpoE |
| M. leprae Br4923 | MLBr_01076 | sigE | 2e-15 | 33.33% (156) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_3543c | - | 1e-50 | 55.49% (182) | RNA polymerase sigma-E factor |
| M. marinum M | MMAR_1334 | sigH | 4e-51 | 56.21% (169) | alternative RNA polymerase sigma-E factor (sigma- 24) SigH |
| M. avium 104 | MAV_4171 | - | 2e-51 | 53.26% (184) | RNA polymerase sigma factor RpoE |
| M. thermoresistible (build 8) | TH_0665 | sigH | 6e-50 | 52.20% (182) | ALTERNATIVE RNA POLYMERASE SIGMA-E FACTOR (SIGMA-24) SIGH |
| M. ulcerans Agy99 | MUL_2545 | sigH | 3e-51 | 56.21% (169) | RNA polymerase sigma factor RpoE |
| M. vanbaalenii PYR-1 | Mvan_1778 | - | 2e-51 | 54.95% (182) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4689|M.gilvum_PYR-GCK -------MVPVMAMKAPSRSVFVLDVIGG-AATEGTVFPTMTD----TNG
Mvan_1778|M.vanbaalenii_PYR-1 -----------MAMEAPSRSVHVLDVIGG-AATEGTVFPTMTD----ITG
TH_0665|M.thermoresistible__bu ----------------------------------------MTD----IEG
Mb3250c|M.bovis_AF2122/97 ----------------------------------------MAD----IDG
Rv3223c|M.tuberculosis_H37Rv ----------------------------------------MAD----IDG
MMAR_1334|M.marinum_M -MSTSTSLLGEERLGRFPASPASVATLSGGTSTEGTVFIKMAD----IDG
MUL_2545|M.ulcerans_Agy99 ----------------------------------------MAD----IDG
MAV_4171|M.avium_104 MVSTATSLLGEEQLAGFLASPGALSVLSGDTAAEGTGFIEMADSPDGPDG
MAB_3543c|M.abscessus_ATCC_199 --------------MACLERPMSVPIRMVGVATERTAVTSMDS----AAE
MSMEG_0573|M.smegmatis_MC2_155 -----------------------------------------MR----IDN
MLBr_01076|M.leprae_Br4923 -MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLIITNLLSP
Mflv_4689|M.gilvum_PYR-GCK LAASPAPADAG------EAREETDAELTARFERDAIPLLDQLYGG-----
Mvan_1778|M.vanbaalenii_PYR-1 SAAEATLDGEA------PAREETDAELTARFERDAIPLLDQLYGG-----
TH_0665|M.thermoresistible__bu TTPIRS--------------EESDAELTARFERDAIPLLDQLYGG-----
Mb3250c|M.bovis_AF2122/97 VTGSAGLQP--------GPSEETDEELTARFERDAIPLLDQLYGG-----
Rv3223c|M.tuberculosis_H37Rv VTGSAGLQP--------GPSEETDEELTARFERDAIPLLDQLYGG-----
MMAR_1334|M.marinum_M VTLAEAPDP--------EPPEETDEQLTARFERDAIPLLDQLYGG-----
MUL_2545|M.ulcerans_Agy99 VTLAEAPDP--------EPPEETDEQLTACFERDAIPLLDQLYGG-----
MAV_4171|M.avium_104 VTSPEVPEAHAEPAAHEETREETDAELTARFERDAIPLLDQLYGG-----
MAB_3543c|M.abscessus_ATCC_199 LPGLVH--------------VETEAERVARFERDALPLLDQLYGA-----
MSMEG_0573|M.smegmatis_MC2_155 VHSSAA-----------------SARDATEFIATALPFVEAIERG-----
MLBr_01076|M.leprae_Br4923 TIMSHPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELVRQHAARV
: ::* : :
Mflv_4689|M.gilvum_PYR-GCK ---ALRMTRNPADAEDLLQETMVKAYSGFRSFREGTNLKAWLYRILTNTY
Mvan_1778|M.vanbaalenii_PYR-1 ---ALRMTRNPADAEDLLQETMVKAYSGFRSFREGTNLKAWLYRILTNTY
TH_0665|M.thermoresistible__bu ---ALRMTRNPADAEDLLQETMVKAYQGFRSFREGTNLKAWLYRILTNTY
Mb3250c|M.bovis_AF2122/97 ---ALRMTRNPADAEDLLQETMVKAYAGFRSFRHGTNLKAWLYRILTNTY
Rv3223c|M.tuberculosis_H37Rv ---ALRMTRNPADAEDLLQETMVKAYAGFRSFRHGTNLKAWLYRILTNTY
MMAR_1334|M.marinum_M ---ALRMTRNPADAEDLLQETMVKAYAGFRSFREGTNLKAWLYRILTNTY
MUL_2545|M.ulcerans_Agy99 ---ALRMTRNPADAEDLLQETMVKAYAGFRSFREGTNLKAWLYRILTNTY
MAV_4171|M.avium_104 ---ALRMTRNPADAEDLLQETMVKAYAGFRSFRAGTNLKAWLYRILTNTY
MAB_3543c|M.abscessus_ATCC_199 ---ALRMTRNPADAEDLVQETMVKAYAGFGTFKEGTNLKAWLYRILTNTY
MSMEG_0573|M.smegmatis_MC2_155 ---ARRLTTNRYDAEDLVQETLLKAYNGFHTFEGGTNMQAWLFRIMRNTW
MLBr_01076|M.leprae_Br4923 YWLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGT-FEGWLHRITTNLF
* *:: * ***** ***:::.: .. .:. ** ::.**.** * :
Mflv_4689|M.gilvum_PYR-GCK INSYRKKQRQPAEYPTEEITDWQLAANAEHTSTGLRSAEVEALELLPDSE
Mvan_1778|M.vanbaalenii_PYR-1 INSYRKKQRQPAEYPTEEITDWQLAANAEHSSTGLRSAEVEALELLPDNE
TH_0665|M.thermoresistible__bu INNYRKRQRQPAVYPTEEFTDWQLASTAEHSSTGLRSAEVEALEALPDTE
Mb3250c|M.bovis_AF2122/97 INSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALPDTE
Rv3223c|M.tuberculosis_H37Rv INSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALPDTE
MMAR_1334|M.marinum_M INSYRKKQRQPAEYPTDEITDWQLASNAEHSSTGLRSAEVEALEALPDTE
MUL_2545|M.ulcerans_Agy99 INSYRKKQRQPAEYPTDEITDWQLASNAEHSSTGLRSAEVEALEALPDTE
MAV_4171|M.avium_104 INSYRKKQRQPAEYPTEEITDWQLASNAEHSSTGLRSAEVEALESLPDSE
MAB_3543c|M.abscessus_ATCC_199 INIYRKKQRQPAEYPTEEITDWQLAANAEHTSTGLRSAEIEALDGLPDDE
MSMEG_0573|M.smegmatis_MC2_155 ISNFRAQQRNPVEQLCEDFTDAQLSAGLRHGADGARSAENEALAHLPDDA
MLBr_01076|M.leprae_Br4923 LDMVRRRAR---------IRMDALPDDYDRVPADEPNPEQIYHDSRLGPD
:. * : * : *. : . . ..* .
Mflv_4689|M.gilvum_PYR-GCK IKEALQALPEDFRMAVYYADVEGFPYKEIAEIMETPIGTVMSRLHRGRRQ
Mvan_1778|M.vanbaalenii_PYR-1 IKEALQALPDEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
TH_0665|M.thermoresistible__bu IKAALQELPEDFRIAVYLADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
Mb3250c|M.bovis_AF2122/97 IKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
Rv3223c|M.tuberculosis_H37Rv IKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
MMAR_1334|M.marinum_M IKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
MUL_2545|M.ulcerans_Agy99 IKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
MAV_4171|M.avium_104 IKDALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
MAB_3543c|M.abscessus_ATCC_199 IKEALNKLPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
MSMEG_0573|M.smegmatis_MC2_155 VLEALRAIPQANRMVVYYADVEGYPYREIATLMDTPIGTVMSRLARGRAR
MLBr_01076|M.leprae_Br4923 LQAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQA
: ** :* * .* .*:** .*.**. : . :*** **: ***
Mflv_4689|M.gilvum_PYR-GCK LRELLAGVARDRGFIRGEQLEAPEEVTS
Mvan_1778|M.vanbaalenii_PYR-1 LRELLAGVARDRGFIRGEQVDAPEEVTS
TH_0665|M.thermoresistible__bu LRSLLADVARERGIIRDQQAGTPEEVSS
Mb3250c|M.bovis_AF2122/97 LRGLLADVARDRGFARGEQ--AHEGVSS
Rv3223c|M.tuberculosis_H37Rv LRGLLADVARDRGFARGEQ--AHEGVSS
MMAR_1334|M.marinum_M LRTLLADVAKERGFVRGEQ--AHQEVSS
MUL_2545|M.ulcerans_Agy99 LRTLLADVAKERGFVRGEQ--AHQEVSS
MAV_4171|M.avium_104 LRGLLADVAKERGFNRGQQ--THEEVSS
MAB_3543c|M.abscessus_ATCC_199 LRDLLSEVAKDRGFLRNNE--LAEGRA-
MSMEG_0573|M.smegmatis_MC2_155 LRVLLADHQAALPAGRAR----------
MLBr_01076|M.leprae_Br4923 LRDYLLTAHPRDGATTDATHVKSA----
** *