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TRTVLIAGSSRGIGAAAARREAANGSRVILHGRSDSPALKELSVELGAPAYHCDGQDADSVQELVDAALA THGRIDALICTLGSVLATDALSGSTDAWIDEYRSNVLGPVNFIRAVAPSMLANGGGRIVTVSSIRGRDNL ASPEVTGYSAAKAALENVTVSFAKALAPSVTVNAVAPGFVLTDMSETWSDEVRKEVATNLLGRAARPEEI AGLLCFLVSDGASFITGQTVLADGGLDAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4163 | - | - | 100% (240) | 3-oxoacyl- |
| M. smegmatis MC2 155 | MSMEG_6340 | - | 1e-28 | 38.11% (244) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_1740 | - | 2e-27 | 33.74% (243) | dehydrogenase/reductase SDR family protein member 4 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2788c | fabG | 1e-31 | 37.24% (239) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_1202 | - | 1e-28 | 36.89% (244) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2766c | fabG | 1e-31 | 37.24% (239) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-22 | 29.29% (239) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0833 | - | 1e-29 | 36.48% (244) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_1952 | fabG | 6e-30 | 36.63% (243) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_3655 | fabG | 1e-29 | 36.13% (238) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. thermoresistible (build 8) | TH_3708 | - | 5e-32 | 35.66% (244) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_2173 | fabG | 2e-29 | 36.21% (243) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_5605 | - | 3e-29 | 36.18% (246) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1202|M.gilvum_PYR-GCK -----MT---GFADRLFDLTDRVVLITGGSRGLGREMAVAAAHCGADVII
Mvan_5605|M.vanbaalenii_PYR-1 -----MTASGGFADQLFDLTDRVVLVTGGSRGLGREMAFAAARCGADVVI
TH_3708|M.thermoresistible__bu -----MT---PDPLAAFRLDGKVALVTGGSRGLGFEMARAFAGAGADVII
MAB_0833|M.abscessus_ATCC_1997 -----MN--RETFSRLFDLTGRTAIVTGGTRGIGRALAEGYACAGANVVV
MSMEG_4163|M.smegmatis_MC2_155 -------------------MTRTVLIAGSSRGIGAAAARREAANGSRVIL
Mb2788c|M.bovis_AF2122/97 -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
Rv2766c|M.tuberculosis_H37Rv -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
MMAR_1952|M.marinum_M -------------MTSLDLTGRTAIITGASRGIGLAIAQRLAGAGANVVL
MUL_2173|M.ulcerans_Agy99 -------------MTSLDLTGRTAIITGASRGIGLAIAQRLAGAGANVVL
MAV_3655|M.avium_104 -------------MTSQDLTGRTAIITGASRGIGLAIAQQLAAAGANVVL
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: :::*..**:* * . * * :
Mflv_1202|M.gilvum_PYR-GCK ASRKYDACVATAEEITAQTGRAALPYGVHVGRWDELDGLVDAAYARFGKV
Mvan_5605|M.vanbaalenii_PYR-1 ASRKYEACVATADEIAAETGRAAFPYQVHVGRWDELDGLVDAAYDRFGRV
TH_3708|M.thermoresistible__bu SSRDEESCRRAAEEIGRTFAVRAVPMPCHVGRWAELDALADRALATFGHV
MAB_0833|M.abscessus_ATCC_1997 ASRKPEACTEAVERLR-SLGARALGVPTHTGDIHSLEELVRATAEEFGGI
MSMEG_4163|M.smegmatis_MC2_155 HGRSD---SPALKELSVELGAPAYHCDGQD--ADSVQELVDAALATHGRI
Mb2788c|M.bovis_AF2122/97 TARRQ----EAADEAAAQVGDRALGVGAHAVDEDAARRCVDLTLERFGSV
Rv2766c|M.tuberculosis_H37Rv TARRQ----EAADEAAAQVGDRALGVGAHAVDEDAARRCVDLTLERFGSV
MMAR_1952|M.marinum_M TARKQ----ESADAAAAEVGERAVGVGAHAVDEEAARGCVDLALERFGSV
MUL_2173|M.ulcerans_Agy99 TARKQ----ESADAAAAEVGERAVGVGAHAVDEEAARGCVDLALERFGSV
MAV_3655|M.avium_104 TARKQ----EAADEAAAQVGPQALGVGAHAVDEDAARQCVQLTLERFGSV
MLBr_01807|M.leprae_Br4923 THRAS------------VVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPV
* . . * :
Mflv_1202|M.gilvum_PYR-GCK DVLVNNAGMSPVYDKQSDVTEKLFDAVVNLNLKGPFRLSALIGERMVADG
Mvan_5605|M.vanbaalenii_PYR-1 DVLVNNAGMSPLYESLSAVTEKLFDSVVNLNLKGPFRLSVLVGDRMVADG
TH_3708|M.thermoresistible__bu DVLVNNAGMSPLYDKVADITETMWEKTLAVNLRAPFRLTALLAPAMVDNG
MAB_0833|M.abscessus_ATCC_1997 DIVVNNAAN-ALTEPVGAFTVDGWDKSFGVNLRGPVFLVQAALPHLVASP
MSMEG_4163|M.smegmatis_MC2_155 DALICTLGSVLATDALS-GSTDAWIDEYRSNVLGPVNFIRAVAPSMLANG
Mb2788c|M.bovis_AF2122/97 DILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEH
Rv2766c|M.tuberculosis_H37Rv DILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEH
MMAR_1952|M.marinum_M DILINNAGTNPAYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMGEH
MUL_2173|M.ulcerans_Agy99 DILINNAGTNPAYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMGEH
MAV_3655|M.avium_104 DILVNNAGTNPAYGPLIEQDHARFAKIFDVNLWAPLLWTSLAVKSWMGEH
MLBr_01807|M.leprae_Br4923 EVLVANAGITSDMLIMR-MSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
: :: . . : *: . . : .
Mflv_1202|M.gilvum_PYR-GCK GGSIVNVSTHG--SLRPHPSFIPYAASKAGLNAMTEGLALAFGPS-VRVN
Mvan_5605|M.vanbaalenii_PYR-1 GGSIINVSTHG--SIRPHPSFVPYAASKAGLNAMTEALALAYGPT-VRVN
TH_3708|M.thermoresistible__bu GGSVINLSSIG--AVRPTADIVPYAAAKAGLNAMTAALAKEYGPH-VRVN
MAB_0833|M.abscessus_ATCC_1997 HAAVLNVVSVG--AFMFGQGVSMYSAAKAALVSYTRSAAAELASRGVRVN
MSMEG_4163|M.smegmatis_MC2_155 GGRIVTVSSIRGRDNLASPEVTGYSAAKAALENVTVSFAKALAPS-VTVN
Mb2788c|M.bovis_AF2122/97 GGAVVNTASIG--GMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVN
Rv2766c|M.tuberculosis_H37Rv GGAVVNTASIG--GMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVN
MMAR_1952|M.marinum_M GGVVINTASIG--GMHQSPAMGMYNATKAALIHVTKQLALELSPR-VRVN
MUL_2173|M.ulcerans_Agy99 GGVVINTASIG--GMHQSPAMGMYNATNAALIHVTKQLALELSPR-VRVN
MAV_3655|M.avium_104 GGSIVNTASIG--GLHQSPAMGMYNATKAALIHVTKQLALELSPR-VRVN
MLBr_01807|M.leprae_Br4923 FGRYIFMGSVVG--LSGVPGQANYAASKSGLIGMARSLARELGSRSITAN
. : : * *:::.* : * .. : .*
Mflv_1202|M.gilvum_PYR-GCK TLMPGPFLTDISNAWNF-EGTDNPFRGSALQRAGQPAEIVGAALFLMSDA
Mvan_5605|M.vanbaalenii_PYR-1 TLMPGPFLTDISDAWTFTDGDTNPFGHSALQRAGQPAEIVGAALFLMSDA
TH_3708|M.thermoresistible__bu AIMPGAFATDVSEYWSA-EAVARVVDQTALGRIGDPREIVGTALYLASDA
MAB_0833|M.abscessus_ATCC_1997 ALAPGAIDTDMVRKTPP-AEVERMANTNHLKRLGLPDEMVGTALLLTSDA
MSMEG_4163|M.smegmatis_MC2_155 AVAPGFVLTDMSETWSD--EVRKEVATNLLGRAARPEEIAGLLCFLVSDG
Mb2788c|M.bovis_AF2122/97 AICPGVVRTRLAEALWK-DHEDPLAATIALGRIGEPADIASAVAFLVSDA
Rv2766c|M.tuberculosis_H37Rv AICPGVVRTRLAEALWK-DHEDPLAATIALGRIGEPADIASAVAFLVSDA
MMAR_1952|M.marinum_M AICPGVVRTKLAEALWK-DHEDPLAANIALGRIGEPVDVAEAVGFLVSDA
MUL_2173|M.ulcerans_Agy99 AICPGVVRTKLAEALWK-DHEDPLAANIALGRIGEPVDVAEAVGFLVSDA
MAV_3655|M.avium_104 AIAPGVVRTRLAEALWK-DHEDPLSSSIALGRIGEPIDVAAAVAFLVSDA
MLBr_01807|M.leprae_Br4923 VVAPGFIDTEMTRAMDS-KYQEAALQAIPLGRIGAVEEIAGAVSFLASED
.: ** . * : * * . ::. * *:
Mflv_1202|M.gilvum_PYR-GCK SSFTTGSIVRADGGSA---------------
Mvan_5605|M.vanbaalenii_PYR-1 SSFTTGSIVRADGGIP---------------
TH_3708|M.thermoresistible__bu ASFTSGAVITVDGGRD---------------
MAB_0833|M.abscessus_ATCC_1997 GSYITGQTIIADGGLVAR-------------
MSMEG_4163|M.smegmatis_MC2_155 ASFITGQTVLADGGLDAR-------------
Mb2788c|M.bovis_AF2122/97 ASWITGETMIIDGGLLLGNALGFRAAPSTEH
Rv2766c|M.tuberculosis_H37Rv ASWITGETMIIDGGLLLGNALGFRAAPSTEH
MMAR_1952|M.marinum_M ASWITGETMVIDGGLLLGSAAGFQSRPGSAS
MUL_2173|M.ulcerans_Agy99 ASWITGETMVIDGGLLLGSAAGFQSRPGSAS
MAV_3655|M.avium_104 ASWITGETLVIDGGTVLGAAQGFRSAPTPS-
MLBr_01807|M.leprae_Br4923 AGYISGAVIPVDGGLGMGH------------
..: :* : ***