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GTIDALDTCERLTRRQKGLAYIATSAICLEFLDYFLIGFIVTFVSTSWQLTFGQSSVILLSSGLGAVVGA VFFGRLADRIGRRPVFLTTITVFTAATAAMAFTPEDASLGWVYLAVLRVVVGFGAGGLYVVDLPMVQEFM PTSKRGRVTGYVTAAVPLGFLVGSLMVWLLSDLIGWRGILLLTGASGLLLLLARFTVPESPRFLLRRRRF EDARKAVGWALQVDPASLPLASSDDDSEHAVDDPAGSSVRELLAYPRSLLLSTVTNLGAQTGVYGIALWA PTLLVMTLGIDPAQAGLYMVFVTMGALAGRLFLSHLSESRGRRFTGALAAFSAAGLVILAAVAGDAYIGG VAVFLVVMIAVYFFAEGGFAVVGPYSAEVWPSRLRATGMGFAYGAGGLGKVVGPLGLGLIVGSDNLVKPD APTTDLLPAFAYFAVWYLLCGCAFLLLGFETRGKNLETLDAEIEARKRNRSGRDSMSAIRG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4049 | - | - | 100% (482) | sugar transporter, permease protein |
| M. smegmatis MC2 155 | MSMEG_3536 | - | 3e-35 | 28.54% (480) | sugar transport protein |
| M. smegmatis MC2 155 | MSMEG_4078 | - | 4e-33 | 29.84% (449) | metabolite transport protein YaaU |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3364 | sugI | 3e-20 | 26.29% (464) | sugar-transport integral membrane protein SugI |
| M. gilvum PYR-GCK | Mflv_1075 | - | 1e-23 | 24.87% (386) | general substrate transporter |
| M. tuberculosis H37Rv | Rv3331 | sugI | 6e-20 | 27.44% (390) | sugar-transport integral membrane protein SugI |
| M. leprae Br4923 | MLBr_01562 | - | 8e-06 | 25.66% (152) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_2263c | - | 6e-19 | 25.21% (468) | major facilitator transporter |
| M. marinum M | MMAR_2574 | - | 6e-34 | 27.58% (417) | sugar transporter |
| M. avium 104 | MAV_3053 | - | 1e-34 | 29.10% (409) | sugar transport protein |
| M. thermoresistible (build 8) | TH_3722 | - | 8e-22 | 25.51% (396) | PUTATIVE General substrate transporter |
| M. ulcerans Agy99 | MUL_3187 | - | 4e-34 | 27.58% (417) | sugar transporter |
| M. vanbaalenii PYR-1 | Mvan_5748 | - | 5e-23 | 25.97% (385) | general substrate transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2574|M.marinum_M -----------------MSARAQTGTISTHVPARLDR-------LPWGRF
MUL_3187|M.ulcerans_Agy99 --------------------------------------------------
MAV_3053|M.avium_104 -----------------MSAGAQTNTITTHVPARLDR-------LPWSRF
Mflv_1075|M.gilvum_PYR-GCK ------------------------------MEVQRD--------SDIRRV
Mvan_5748|M.vanbaalenii_PYR-1 ----------------------------------ME--------TDIRRV
TH_3722|M.thermoresistible__bu --------------------VSENPSIVSAPPAPDA--------VVIRKA
MAB_2263c|M.abscessus_ATCC_199 -----------------MSSAGPREGETEPPPVPRPDFQSPEGRRQLHRA
Mb3364|M.bovis_AF2122/97 ---MTTLWQPHRNDYSPIPGRGVHARRGARRPRPRGGRAERPGTGQLTRS
Rv3331|M.tuberculosis_H37Rv ---MTTLWQPHRNDYSPIPGRGVHARRGARRPRPRGGRAERPGTGQLTRS
MSMEG_4049|M.smegmatis_MC2_155 --------------------MGTIDALDTCERLTRRQ----------KGL
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
MMAR_2574|M.marinum_M HWRVVIGLGGVWVLDGLEVTMVGNVSARLTEHGSGINLTPAQIGVAASFY
MUL_3187|M.ulcerans_Agy99 ----MIGLGGVWVLDGLEVTMVGNVSARLTEHGSGINLTPAQIGVAASFY
MAV_3053|M.avium_104 HWRVVIGLGGVWVLDGLEVTMVGNVSARLMEPGSGIALNPAQIGMAAAIY
Mflv_1075|M.gilvum_PYR-GCK VTGASIGNAVEWFDFAIYGFLATFIAAQFFPAGNDTAALLNTFAIFAAAF
Mvan_5748|M.vanbaalenii_PYR-1 VTGASIGNAVEWFDFAIYGFLATFIAAHFFPAGNDTAALLNTFAIFAAAF
TH_3722|M.thermoresistible__bu VTGASIGNAVEWFDFAIYGFLATYIAANFFPAGDDTAALLNTFAIFAAAF
MAB_2263c|M.abscessus_ATCC_199 IAASAMGNATEWYDYGVYAATTTFLTQAFFPTLGTAFTMLG----YAISF
Mb3364|M.bovis_AF2122/97 GRRALLVGLTAASVGVLYGYDLSAIAGALLSLSEEFELTTREQELLTTTA
Rv3331|M.tuberculosis_H37Rv GRRALLVGLTAASVGVLYGYDLSAIAGALLSLSEEFELTTREQELLTTTA
MSMEG_4049|M.smegmatis_MC2_155 AYIATSAICLEFLDYFLIGFIVTFVSTSWQLTFGQSSVILLSSG------
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA
: ::
MMAR_2574|M.marinum_M IAGACLGALFFG-HLTDRFGRRNLFLLTLAVYLTATVATAFA--------
MUL_3187|M.ulcerans_Agy99 IAGACLGALFFG-HLTDRFGRRNLFLLTLAVYLTATVATAFA--------
MAV_3053|M.avium_104 IAGACSGALFFG-HLTDRFGRRNLFILTLALYLIATVATAFA--------
Mflv_1075|M.gilvum_PYR-GCK FMRP-LGGFFFG-PLGDRIGRQKVLAVVILLMSAATLCIGLLPTYDAIGV
Mvan_5748|M.vanbaalenii_PYR-1 FMRP-LGGFFFG-PLGDRIGRQKVLAVVILLMSAATLGIGLLPTYEAIGV
TH_3722|M.thermoresistible__bu VVRP-LGGFFFG-PLGDRIGRQRVLALVILLMSGATLTMGLLPTYESIGV
MAB_2263c|M.abscessus_ATCC_199 LLRP-LGGMVWG-PLGDRLGRKSVMAITIVLMALSTTLIGILPSWATIGM
Mb3364|M.bovis_AF2122/97 VLGQIAGALGGG-ILANAIGRKKSVVLIVAGYAVFALLGATS--------
Rv3331|M.tuberculosis_H37Rv VLGQIAGALGGG-ILANAIGRKKSVVLIVAGYAVFALLGATS--------
MSMEG_4049|M.smegmatis_MC2_155 -LGAVVGAVFFG-RLADRIGRRPVFLTTITVFTAATAAMAFTPEDAS---
MLBr_01562|M.leprae_Br4923 YVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVA--------
* . * * : :**: . : : .
MMAR_2574|M.marinum_M FAPWYFFIARFFTGSGIGGEYAAINSAIDELIPA-RVRGRVDLIINGTYW
MUL_3187|M.ulcerans_Agy99 FAPWYFFIARFFTGSGIGGEYAAINSAIDELIPA-RVRGRVDLIINGTYW
MAV_3053|M.avium_104 FAPWYFFLTRFFTGAGIGGEYAAINSAIDELIPA-RVRGRVDLVINGTYW
Mflv_1075|M.gilvum_PYR-GCK AAPLLLLVLRCLQGFSAGGEYGGGAVYLAEFASD-RRRGLTITFMAWSGV
Mvan_5748|M.vanbaalenii_PYR-1 AAPMLLLVLRCLQGFSAGGEYGGGAVYLAEFASD-ARRGLTITFMAWSGV
TH_3722|M.thermoresistible__bu LAPLLLLLLRCLQGFSAGGEYGGGAVYLAEFAPD-RRRGLIVTFMAWSGV
MAB_2263c|M.abscessus_ATCC_199 AAPALLILLRVIQGFSTGGEYGGAATFMAEFAPD-KKRGKYGSFLEFGTL
Mb3364|M.bovis_AF2122/97 VSVPMLVVARLLLGVTIGLSVVVVPVYVAESAPA-AVRGSLVTAYQLATL
Rv3331|M.tuberculosis_H37Rv VSVPMLVVARLLLGVTIGLSVVVVPVYVAESAPA-AVRGSLVTAYQLATL
MSMEG_4049|M.smegmatis_MC2_155 LGWVYLAVLRVVVGFGAGGLYVVDLPMVQEFMPT-SKRGRVTGYVTAAVP
MLBr_01562|M.leprae_Br4923 WDEVTLVIARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTA
: : * . * . : . *.
MMAR_2574|M.marinum_M LGSAAGAAGALVLLDTS--NFAPNMGWRLAFGLGAIFGIFVLLVR-----
MUL_3187|M.ulcerans_Agy99 LGSAAGAAGALVLLDTS--NFAPNMGWRLAFGLGAIFGIFVLLVR-----
MAV_3053|M.avium_104 LGSAAGAGGALILLDTS--NFAADLGWRLAFGIGAILGIFVLLVR-----
Mflv_1075|M.gilvum_PYR-GCK VGFLLGSVTVTLLQALLPAEAMESYGWRIPFLIAGPLGLVGLYIR-----
Mvan_5748|M.vanbaalenii_PYR-1 LGFLIGSVTVTLLQALLPAAAMESYGWRIPFLIAGPLGLVGLYIR-----
TH_3722|M.thermoresistible__bu LGFLLGSVTVTALQVALPDQVMTDVGWRIPFLLAGPLGLIGLYIR-----
MAB_2263c|M.abscessus_ATCC_199 GGFAVGAAFVLVLDATLSDDAMHTWGWRIPFLVALPMGLIGWYLR-----
Mb3364|M.bovis_AF2122/97 SGIVVGYLVGYLLAGSH--------GWRAMFGLAAAPATLLLPLL-----
Rv3331|M.tuberculosis_H37Rv SGIVVGYLVGYLLAGSH--------GWRAMFGLAAAPATLLLPLL-----
MSMEG_4049|M.smegmatis_MC2_155 LGFLVGSLMVWLLSDLI--------GWRGILLLTGASGLLLLLAR-----
MLBr_01562|M.leprae_Br4923 IGSVMGLVVGGALTEVS---------WRLAFLVNVPIGLVMIYLARTALH
* * * ** : : . .
MMAR_2574|M.marinum_M ------RNVPESPRWLFIHGREQEAEQIVREIEEEVERDTGQRLPDPPGR
MUL_3187|M.ulcerans_Agy99 ------RNVPESPRWLFIHGREQEAEQIVREIEEEVERDTGQRLPDPPGR
MAV_3053|M.avium_104 ------RNVPESPRWLFIHGREEEAEHIVGEIEEAVQQQTGRPLPEPQGK
Mflv_1075|M.gilvum_PYR-GCK ------LRLGDTPQFAELAKAD----KKAESPLREAVATS----------
Mvan_5748|M.vanbaalenii_PYR-1 ------LRLGDTPQFAELDKAE----KTADSPLREAVTTS----------
TH_3722|M.thermoresistible__bu ------LRLDDTPAFTALSEQE----EVAQSPLREAVQTA----------
MAB_2263c|M.abscessus_ATCC_199 ------SRLDDPPLFKEMQEQEPEGRETAFERLRDLVRDY----------
Mb3364|M.bovis_AF2122/97 ------WRMPDTARWYLLKGRIADARSALRRIQPEADIDAELADMAAAVD
Rv3331|M.tuberculosis_H37Rv ------WRMPDTARWYLLKGRIADARSALRRIQPEADIDAELADMAAAVD
MSMEG_4049|M.smegmatis_MC2_155 ------FTVPESPRFLLRRRRFEDARKAVGWALQVDPASLPLASSDDDSE
MLBr_01562|M.leprae_Br4923 ETHKERMKLDAAGAILATLACTAAVFAFSMGPEKGWISLTTIGSGLVALV
: .
MMAR_2574|M.marinum_M PLKIRQRQRISLWEIARVAFTRYPRRAFLGLALFIGQAFLYNGVTFNLGT
MUL_3187|M.ulcerans_Agy99 PLKIRQRQRISLWEIARVAFTRYPRRAFLGLALFIGQAFLYNGVTFNLGT
MAV_3053|M.avium_104 ALRIRQRTAISFREIAAVAFKLYPRRAVLGLALFIGQAFLYNGVTFNLGT
Mflv_1075|M.gilvum_PYR-GCK -----------------------WRQILQVVGLFIVFNIGYYVVFTFLPT
Mvan_5748|M.vanbaalenii_PYR-1 -----------------------WRQIIQVIGLFIVFNIGYYVVFTFLPT
TH_3722|M.thermoresistible__bu -----------------------WRSILQVIGLMIIFNVAYYVVFAYMPT
MAB_2263c|M.abscessus_ATCC_199 -----------------------RRPMVVMMLLVIALNITNYTLLSYQPT
Mb3364|M.bovis_AF2122/97 ERG---------GGIGEMVRRPYLRATLFVIALGFLVQITGINAIIYYSP
Rv3331|M.tuberculosis_H37Rv ERG---------GGIGEMVRRPYLRATLFVIALGFLVQITGINAIIYYSP
MSMEG_4049|M.smegmatis_MC2_155 HAVDDP------AGSSVRELLAYPRSLLLSTVTNLGAQTGVYGIALWAPT
MLBr_01562|M.leprae_Br4923 AAIAFAVVERTAENPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGL
* . :
MMAR_2574|M.marinum_M LLSGFYGVESGHVPLFF-IVWALSNFVGPLVLGRLFDTVGRKPMITMSYI
MUL_3187|M.ulcerans_Agy99 LLSGFYGVESGHVPLFF-IVWALSNFVGPLVLGRLFDTVGRKPMITMSYI
MAV_3053|M.avium_104 LLSQFYAVPSGMVPVFF-VLWALSNFAGPLLLGHLFDTVGRKQMITLTYI
Mflv_1075|M.gilvum_PYR-GCK YFIKTLGFTKSYSFLSI-TLACLVALILILPLAALSDRFGRRPLLIGGAV
Mvan_5748|M.vanbaalenii_PYR-1 YFIKTLRFSKSEAFVSI-TLACLVALILILPLAALSDRIGRRPLLIGGAV
TH_3722|M.thermoresistible__bu YLIKELGLSSSDAFISS-TIACVVALVLILPLAALSDRIGRKPLLVGGAI
MAB_2263c|M.abscessus_ATCC_199 YLKTRLGMSETQGQIVI-LIGEVAMMAFLPFCGALSDRVGRKPMWAFSLT
Mb3364|M.bovis_AF2122/97 RLFAAMGFAGYFAMLALPAMVQVAGLAAVCASLFLVDRLGRRPILLSGIA
Rv3331|M.tuberculosis_H37Rv RLFAAMGFAGYFAMLALPAMVQVAGLAAVCASLFLVDRLGRRPILLSGIA
MSMEG_4049|M.smegmatis_MC2_155 LLVMTLGIDPAQAGLYM-VFVTMGALAGRLFLSHLSESRGRRFTGALAAF
MLBr_01562|M.leprae_Br4923 YIQDILGYSALRAGIGFIPFVIAMGIG----LGVSSQLVSRFSPRVLTIG
: : . : : .*
MMAR_2574|M.marinum_M GSAVIAVVLAVIFVNQTGGVWTFIIVLAAAFFLAS----AGASAAYLTVS
MUL_3187|M.ulcerans_Agy99 GSAVIAVVLAVIFVNQTGGVWTFIIVLAAAFFLAS----AGASAAYLTVS
MAV_3053|M.avium_104 GSAVVVVALALVFLTQAGGVWAFIGVLIVAFFLAS----AGASAAYLTVS
Mflv_1075|M.gilvum_PYR-GCK A--FIVLGYPLFLLITSGSPVAAITGHCLLAAIES----VYISCAVSAGV
Mvan_5748|M.vanbaalenii_PYR-1 S--FAVLGYPLFLLLTSGSLVAAITAHCLLAAIAS----VYISSAVSAGV
TH_3722|M.thermoresistible__bu A--FAVLAYPLFLLLNSGSTAAAMIAHAGLAAIES----VVISVAVVTAV
MAB_2263c|M.abscessus_ATCC_199 G--LLVLSLPMFWLMGQG-FGWAIVGFAVLGLLYI----PQLSTITATFP
Mb3364|M.bovis_AF2122/97 TMITADAVLITVFANDSDGGTGLVLGFAGVLLFIIGFNFGFGSLVWVYAA
Rv3331|M.tuberculosis_H37Rv TMITADAVLITVFANDSDGGTGLVLGFAGVLLFIIGFNFGFGSLVWVYAA
MSMEG_4049|M.smegmatis_MC2_155 SAAGLVILAAVAGDAYIGGVAVFLVVMIAVYFFAEG----GFAVVGPYSA
MLBr_01562|M.leprae_Br4923 GGWLLMVAMLYGWAFMNRGVPYFPNLLAPIVVGGIG-----IGMAVVPLT
.
MMAR_2574|M.marinum_M EIFPMETRALAIAFFYAVGTAIGGISGPLLFGQLIE-------SGQRSQV
MUL_3187|M.ulcerans_Agy99 EIFPMETRALAIAFFYAVGTAIGGISGPLLFGQLIE-------SGQRSQV
MAV_3053|M.avium_104 EIFPMETRALAIAFFYAMGTAIGGITGPLLFGQLID-------SGQRDHV
Mflv_1075|M.gilvum_PYR-GCK ELFATRVRFSGFSVGYNICVAVFGGTTPYVVTWLTA-------TTGNSIA
Mvan_5748|M.vanbaalenii_PYR-1 ELFATRIRFSGFSVGYNVCVAVFGGTTPYVVTWLTA-------ASGNAIA
TH_3722|M.thermoresistible__bu EQFTTRVRYSGMSVGYNVCVALFGGTTPYVMTWLID-------TTANPLA
MAB_2263c|M.abscessus_ATCC_199 CMFPTQVRYAGFAISYNLSTAAFGGTAPLVNDLVVA-------RTGWDLF
Mb3364|M.bovis_AF2122/97 ESFPSRLRSMGSSLMLTSTLTANAIVAAFSLTMLRV-------LGG----
Rv3331|M.tuberculosis_H37Rv ESFPSRLRSMGSSPMLTSTLTANAIVAAFSLTMLRV-------LGG----
MSMEG_4049|M.smegmatis_MC2_155 EVWPSRLRATGMGFAYGAG-GLGKVVGPLGLGLIVGSDNLVKPDAPTTDL
MLBr_01562|M.leprae_Br4923 LSAIAGVGFDRIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTG
. . :
MMAR_2574|M.marinum_M FWSFIIGAAVMAVAGLVELWLGIAAEQRPLEELALPLTVADAEDDDEPAD
MUL_3187|M.ulcerans_Agy99 FWSFIIGAAVMAVAGLVELWLGIAAEQRPLEELALPLTVVDAEDDDEPAD
MAV_3053|M.avium_104 VWSFLIGAVVMAAAGLVELWLGIAAEQRPLEDLALPLTVDDAEDTEPQGD
Mflv_1075|M.gilvum_PYR-GCK PAFYLIAAAAVSLAAVLTLR---ETARRPLAQVPYNRADEAPGVALRQHR
Mvan_5748|M.vanbaalenii_PYR-1 PAFYLIAAAVVSLAAVLTLR---ESAGRALAQVQERPANVGSGIHEGEMR
TH_3722|M.thermoresistible__bu PACAVTLAAVVSLGVVMTLR---ETAARPLAGTP----------------
MAB_2263c|M.abscessus_ATCC_199 PAAYLMVACVVGLCALPFLI---ETAGASIAGTEIPCNEAAVPTDTVRA-
Mb3364|M.bovis_AF2122/97 AGVFAVFGTFAVVAFVVVYRFAPETKGRKLEEIRHFWENGGRWPAERSPA
Rv3331|M.tuberculosis_H37Rv AGVFAVFGTFAVVAFVVVYRFAPETKGRKLEEIRHFWENGGRWPAERSPA
MSMEG_4049|M.smegmatis_MC2_155 LPAFAYFAVWYLLCGCAFLLLGFETRGKNLETLDAEIEARKRNRSGRDSM
MLBr_01562|M.leprae_Br4923 PVKFMNDAQLRALDHGYTYGLLWVAGAVVIVGVAALFIGYTPEQVAYAQE
. : :
MMAR_2574|M.marinum_M GAGARGAQHPGS
MUL_3187|M.ulcerans_Agy99 GAGARGAQHPGS
MAV_3053|M.avium_104 SAPVD-------
Mflv_1075|M.gilvum_PYR-GCK DR----------
Mvan_5748|M.vanbaalenii_PYR-1 R-----------
TH_3722|M.thermoresistible__bu ------------
MAB_2263c|M.abscessus_ATCC_199 ------------
Mb3364|M.bovis_AF2122/97 ADEP--------
Rv3331|M.tuberculosis_H37Rv ADEP--------
MSMEG_4049|M.smegmatis_MC2_155 SAIRG-------
MLBr_01562|M.leprae_Br4923 VKEAVDAGEL--