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MNPLDVMDRPAKGGFHTRILVACCGGPFLDGYVMSIIGVALLGVSEQLNPTTAESGLIGAASLIGIFFGA TLFGFLTDRIGREKMYALDLVVLVVACALSVFVTAPWQLIVLRLVIGAAIGADYPIATSLLTEFTPTRKR GAMVGMSAVAWSAGAVSAYIVGAIVVAASGGNDNWRWLLATSAILGVIVILARRGIPESPRWLLRQGRIS DAEDVVERIYGVRPTLSAITDEPHVESPKRELTQFLRGEYLKRIVMCSMLYLAVVTPLYALLTYLPTILT GFHIQGDGPSGLLVETVIIGLTVAGSILSLYLVEHWGRRPLAVVPLGLMVLPLVGLWLWGDAPLWFVVAA FCAYSFISGGPSILVWIYPNELFPTEFRATAVGLTTGISRFGAATGTYLLPLSISTLGVGITMLFGAILT AAAFATCALLATETKDRSLEEASAIEASPTTPSRSERTPDKRSVV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4078 | - | - | 100% (465) | metabolite transport protein YaaU |
| M. smegmatis MC2 155 | MSMEG_2966 | - | 3e-91 | 40.22% (455) | major facilitator family protein transporter |
| M. smegmatis MC2 155 | MSMEG_3536 | - | 3e-37 | 28.57% (469) | sugar transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3364 | sugI | 6e-32 | 26.95% (423) | sugar-transport integral membrane protein SugI |
| M. gilvum PYR-GCK | Mflv_3055 | - | 4e-23 | 24.41% (463) | sugar transporter |
| M. tuberculosis H37Rv | Rv3331 | sugI | 1e-31 | 26.71% (423) | sugar-transport integral membrane protein SugI |
| M. leprae Br4923 | MLBr_00430 | - | 8e-05 | 23.89% (180) | hypothetical protein MLBr_00430 |
| M. abscessus ATCC 19977 | MAB_0365c | - | 5e-33 | 26.56% (433) | sugar-transport integral membrane protein |
| M. marinum M | MMAR_2574 | - | 4e-37 | 27.06% (462) | sugar transporter |
| M. avium 104 | MAV_3053 | - | 2e-36 | 27.92% (480) | sugar transport protein |
| M. thermoresistible (build 8) | TH_3722 | - | 2e-13 | 24.43% (397) | PUTATIVE General substrate transporter |
| M. ulcerans Agy99 | MUL_3187 | - | 5e-34 | 26.82% (440) | sugar transporter |
| M. vanbaalenii PYR-1 | Mvan_3472 | - | 2e-25 | 25.27% (459) | sugar transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3364|M.bovis_AF2122/97 MTTLWQPHRNDYSPIPGRGVHARRGARRPRPRGGRAERPGTGQLTRSGRR
Rv3331|M.tuberculosis_H37Rv MTTLWQPHRNDYSPIPGRGVHARRGARRPRPRGGRAERPGTGQLTRSGRR
MAB_0365c|M.abscessus_ATCC_199 -----------MSLIT--------------------------DLRSTSRL
Mflv_3055|M.gilvum_PYR-GCK MAGQGGPAGESPELYE------------------------KGQDFSSGKT
Mvan_3472|M.vanbaalenii_PYR-1 MAGQGGPVGDGPEIFE------------------------QGQEFSSGKT
MMAR_2574|M.marinum_M -MSARAQTGTISTHVP-----------------------ARLDRLPWGRF
MUL_3187|M.ulcerans_Agy99 --------------------------------------------------
MAV_3053|M.avium_104 -MSAGAQTNTITTHVP-----------------------ARLDRLPWSRF
MSMEG_4078|M.smegmatis_MC2_155 -----------MNPLD------------------------VMDRPAKGGF
TH_3722|M.thermoresistible__bu -------VSENPSIVS-------------------------APPAPDAVV
MLBr_00430|M.leprae_Br4923 ---MNQPESVAGTMVR-----------------------SWVVAWAMWDC
Mb3364|M.bovis_AF2122/97 ALLVGLTAASVGVLYGYDLSAIAGALLSLSEE---FELTTREQE---LLT
Rv3331|M.tuberculosis_H37Rv ALLVGLTAASVGVLYGYDLSAIAGALLSLSEE---FELTTREQE---LLT
MAB_0365c|M.abscessus_ATCC_199 GVMVAVTAAAVGVIYGYDSSNIAGALLFLTED---LHLSTHDQQ---VAA
Mflv_3055|M.gilvum_PYR-GCK AIRIASVAALGGLLFGYDSAVINGAVASIQED---FGIGNYALG---LAV
Mvan_3472|M.vanbaalenii_PYR-1 AVRIASVAALGGLLFGYDSAVINGAVDSIQED---FGIGNAELG---FAV
MMAR_2574|M.marinum_M HWRVVIGLGGVWVLDGLEVTMVGNVSARLTEHGSGINLTPAQIG---VAA
MUL_3187|M.ulcerans_Agy99 ----MIGLGGVWVLDGLEVTMVGNVSARLTEHGSGINLTPAQIG---VAA
MAV_3053|M.avium_104 HWRVVIGLGGVWVLDGLEVTMVGNVSARLMEPGSGIALNPAQIG---MAA
MSMEG_4078|M.smegmatis_MC2_155 HTRILVACCGGPFLDGYVMSIIGVALLGVSEQ---LNPTTAESG---LIG
TH_3722|M.thermoresistible__bu IRKAVTGASIGNAVEWFDFAIYGFLATYIAANFFPAGDDTAALLNTFAIF
MLBr_00430|M.leprae_Br4923 GSTGLTAIVATFVFSVYLTSSVGVGMPDGISLVSWLGRAGAVAG-----L
. :
Mb3364|M.bovis_AF2122/97 TTAVLGQIAGALGGGILANAIGRKKSVVLIVAGY--------AVFALLGA
Rv3331|M.tuberculosis_H37Rv TTAVLGQIAGALGGGILANAIGRKKSVVLIVAGY--------AVFALLGA
MAB_0365c|M.abscessus_ATCC_199 TAVVIGEIFGALIGGPLSNKIGRKRSMVLVAATF--------GIFSLLSA
Mflv_3055|M.gilvum_PYR-GCK ASALLGAAVGALSAGRIADRIGRIAVMKIAAVLF--------LLSAFGTA
Mvan_3472|M.vanbaalenii_PYR-1 ASALLGAAAGAMTAGRIADRIGRIAVMKIAAVLF--------LVSAFGTG
MMAR_2574|M.marinum_M SFYIAGACLGALFFGHLTDRFGRRNLFLLTLAVY--------LTATVATA
MUL_3187|M.ulcerans_Agy99 SFYIAGACLGALFFGHLTDRFGRRNLFLLTLAVY--------LTATVATA
MAV_3053|M.avium_104 AIYIAGACSGALFFGHLTDRFGRRNLFILTLALY--------LIATVATA
MSMEG_4078|M.smegmatis_MC2_155 AASLIGIFFGATLFGFLTDRIGREKMYALDLVVL--------VVACALSV
TH_3722|M.thermoresistible__bu AAAFVVRPLGGFFFGPLGDRIGRQRVLALVILLMSGATLTMGLLPTYESI
MLBr_00430|M.leprae_Br4923 TIAVLAPAIGVWVESPHRRRVTLGVLTVLAVALT-----------CGMSF
: . * . . :
Mb3364|M.bovis_AF2122/97 TSVSVPMLVVARLLLGVTIGLSVVVVPVYVAESAPAAVRGSLVTAYQLAT
Rv3331|M.tuberculosis_H37Rv TSVSVPMLVVARLLLGVTIGLSVVVVPVYVAESAPAAVRGSLVTAYQLAT
MAB_0365c|M.abscessus_ATCC_199 LAVDLNTLAAARFLLGLTVGVSVVVVPVFVAESSPTKIRGSMLVLYQLAC
Mflv_3055|M.gilvum_PYR-GCK FAPETITLVIGRIVGGVGVGVASVIAPAYIAETSPPGIRGRLGSLQQLAI
Mvan_3472|M.vanbaalenii_PYR-1 FAHEVWAVVLFRIVGGIGVGVASVIAPAYIAETSPPGIRGRLGSLQQLAI
MMAR_2574|M.marinum_M FAFAPWYFFIARFFTGSGIGGEYAAINSAIDELIPARVRGRVDLIINGTY
MUL_3187|M.ulcerans_Agy99 FAFAPWYFFIARFFTGSGIGGEYAAINSAIDELIPARVRGRVDLIINGTY
MAV_3053|M.avium_104 FAFAPWYFFLTRFFTGAGIGGEYAAINSAIDELIPARVRGRVDLVINGTY
MSMEG_4078|M.smegmatis_MC2_155 FVTAPWQLIVLRLVIGAAIGADYPIATSLLTEFTPTRKRGAMVGMSAVAW
TH_3722|M.thermoresistible__bu GVLAPLLLLLLRCLQGFSAGGEYGGGAVYLAEFAPDRRRGLIVTFMAWSG
MLBr_00430|M.leprae_Br4923 IRDQPSYLWAGLMLLAGTAACGDLASVPYNAMLRQLSTPATAGRISGLGW
. . . . .
Mb3364|M.bovis_AF2122/97 LSGIVVGYLVGYLLAGSHG------------WRAMFGLAAAPATLLLPLL
Rv3331|M.tuberculosis_H37Rv LSGIVVGYLVGYLLAGSHG------------WRAMFGLAAAPATLLLPLL
MAB_0365c|M.abscessus_ATCC_199 VTGIIAGYLIAWALSSTGS------------WRLMLGLAAVPAALVLIAL
Mflv_3055|M.gilvum_PYR-GCK VSGIFASFAVNYLLQWLAGGPNEPLWLGMDAWRWMFLAMAVPAVVYGGLA
Mvan_3472|M.vanbaalenii_PYR-1 VSGIFASFAVNWLLQWAAGGPNEPLWFGLDAWRWMFLAMALPAVLYGVLA
MMAR_2574|M.marinum_M WLGSAAGAAGALVLLDTSN------FAPNMGWRLAFGLGAIFGIFVLLVR
MUL_3187|M.ulcerans_Agy99 WLGSAAGAAGALVLLDTSN------FAPNMGWRLAFGLGAIFGIFVLLVR
MAV_3053|M.avium_104 WLGSAAGAGGALILLDTSN------FAADLGWRLAFGIGAILGIFVLLVR
MSMEG_4078|M.smegmatis_MC2_155 SAGAVSAYIVGAIVVAASG--------GNDNWRWLLATSAILGVIVILAR
TH_3722|M.thermoresistible__bu VLGFLLGSVTVTALQVALP----DQVMTDVGWRIPFLLAGPLGLIGLYIR
MLBr_00430|M.leprae_Br4923 ASGYVG--SVVLLLLIYLG--------------FISGTGELRGLLQLPTH
* : . .
Mb3364|M.bovis_AF2122/97 WRMPDTARWYLLKGRIADARSALRRIQPEAD--IDAELADMAAAVDERGG
Rv3331|M.tuberculosis_H37Rv WRMPDTARWYLLKGRIADARSALRRIQPEAD--IDAELADMAAAVDERGG
MAB_0365c|M.abscessus_ATCC_199 LKLPDTARWYMMRGDRARAREVLSMVDRDVD--IDHELDEIAEALRAEGG
Mflv_3055|M.gilvum_PYR-GCK FTIPESPRYLVATHKIPEARRVLSMLLGQKN--LEITITRIRETLEREDR
Mvan_3472|M.vanbaalenii_PYR-1 FTIPESPRYLVASHKIPEARRVLSMLLGKKN--LEITITRIRETLEREDK
MMAR_2574|M.marinum_M RNVPESPRWLFIHGREQEAEQIVREIEEEVERDTGQRLPDPPGRPLKIRQ
MUL_3187|M.ulcerans_Agy99 RNVPESPRWLFIHGREQEAEQIVREIEEEVERDTGQRLPDPPGRPLKIRQ
MAV_3053|M.avium_104 RNVPESPRWLFIHGREEEAEHIVGEIEEAVQQQTGRPLPEPQGKALRIRQ
MSMEG_4078|M.smegmatis_MC2_155 RGIPESPRWLLRQGRISDAEDVVERIYGVRP-----TLSAITDEPHVESP
TH_3722|M.thermoresistible__bu LRLDDTPAFTALSEQEEVAQSPLREAVQTAW-------------------
MLBr_00430|M.leprae_Br4923 DGIYVRAAMLLAAAWLALLALPLLLTAHRLP-----SLGEVSHPTSMLGG
: . :
Mb3364|M.bovis_AF2122/97 G-----IGEMVRRP--YLRATLFVIALGFLVQITGINAIIYYSPRLFAAM
Rv3331|M.tuberculosis_H37Rv G-----IGEMVRRP--YLRATLFVIALGFLVQITGINAIIYYSPRLFAAM
MAB_0365c|M.abscessus_ATCC_199 GSVRARLREMVTAP--YRRATFFVVGLGFFIQITGINAVVYYGPRIFEAM
Mflv_3055|M.gilvum_PYR-GCK PS----WRDLKKPTGGIYGIVWVGLGLSIFQQFVGINVIFYYSNVLWQAV
Mvan_3472|M.vanbaalenii_PYR-1 PS----WRDMRKPTGGLYGIVWVGLGLSIFQQFVGINVIFYYSNVLWQAV
MMAR_2574|M.marinum_M RQRISLWEIARVAFTRYPRRAFLGLAL-FIGQAFLYNGVTFNLGTLLSGF
MUL_3187|M.ulcerans_Agy99 RQRISLWEIARVAFTRYPRRAFLGLAL-FIGQAFLYNGVTFNLGTLLSGF
MAV_3053|M.avium_104 RTAISFREIAAVAFKLYPRRAVLGLAL-FIGQAFLYNGVTFNLGTLLSQF
MSMEG_4078|M.smegmatis_MC2_155 K------RELTQFLRGEYLKRIVMCSMLYLAVVTPLYALLTYLPTILTGF
TH_3722|M.thermoresistible__bu ------------------RSILQVIGLMIIFNVAYYVVFAYMPTYLIKEL
MLBr_00430|M.leprae_Br4923 YR-----KLWSEVSAEWRRDRNLVYFLVASALFRDGLAATLGFGAVLGVN
: :
Mb3364|M.bovis_AF2122/97 GFAGYFAMLALPAMVQV-AGLAAVCASLFLVDRLGRRPILLSGIATMITA
Rv3331|M.tuberculosis_H37Rv GFAGYFAMLALPAMVQV-AGLAAVCASLFLVDRLGRRPILLSGIATMITA
MAB_0365c|M.abscessus_ATCC_199 GMSGYFAKLGLPALVQV-AALLAVFISMSSIDRMGRRPILMIGIGIMIVA
Mflv_3055|M.gilvum_PYR-GCK GFS-ADESAVYTVITSV-VNVLTTLIAIALIDKIGRKPLLLIGSVGMAVT
Mvan_3472|M.vanbaalenii_PYR-1 GFS-ADESAVYTVITSV-INVLTTLIAIALIDKIGRKPLLLIGSSGMAVT
MMAR_2574|M.marinum_M YGVESGHVPLFFIVWAL-SNFVGPLVLGRLFDTVGRKPMITMSYIGSAVI
MUL_3187|M.ulcerans_Agy99 YGVESGHVPLFFIVWAL-SNFVGPLVLGRLFDTVGRKPMITMSYIGSAVI
MAV_3053|M.avium_104 YAVPSGMVPVFFVLWAL-SNFAGPLLLGHLFDTVGRKQMITLTYIGSAVV
MSMEG_4078|M.smegmatis_MC2_155 HIQGDGPSGLLVETVIIGLTVAGSILSLYLVEHWGRRPLAVVPLGLMVLP
TH_3722|M.thermoresistible__bu GLSSSDAFISSTIACVV--ALVLILPLAALSDRIGRKPLLVGGAIAFAVL
MLBr_00430|M.leprae_Br4923 AYGISQANVLMFGVVASLVAAVGAVLGGFVDHRIGSKRVIVGSLVAIIVT
. * : :
Mb3364|M.bovis_AF2122/97 DAVLITVFAN------------DSDGGTGLVLGFAGVLLFIIGFNFGFGS
Rv3331|M.tuberculosis_H37Rv DAVLITVFAN------------DSDGGTGLVLGFAGVLLFIIGFNFGFGS
MAB_0365c|M.abscessus_ATCC_199 DALLVGVFAVG----------GSSFGGLLTFLGFLGIVLIAVGFTFGFGS
Mflv_3055|M.gilvum_PYR-GCK LSTMAFIFANAELIENEAGEMVPSLPGASGVIALIAANLFVVAFGMSWGP
Mvan_3472|M.vanbaalenii_PYR-1 LITMAVIFANATVGADGN----PSLPGASGVIALIAANLFVVAFGMSWGP
MMAR_2574|M.marinum_M AVVLAVIFVN----------------QTGGVWTFIIVLAAAFFLASAGAS
MUL_3187|M.ulcerans_Agy99 AVVLAVIFVN----------------QTGGVWTFIIVLAAAFFLASAGAS
MAV_3053|M.avium_104 VVALALVFLT----------------QAGGVWAFIGVLIVAFFLASAGAS
MSMEG_4078|M.smegmatis_MC2_155 LVGLWLWG-------------------DAPLWFVVAAFCAYSFISGGPSI
TH_3722|M.thermoresistible__bu AYPLFLLLNS------------------GSTAAAMIAHAGLAAIESVVIS
MLBr_00430|M.leprae_Br4923 ALTLMTLSGP---------------------LAFWVCGLVLCLFIGPSQS
: :
Mb3364|M.bovis_AF2122/97 LVWVYAAESFPSRLRSMGSSLMLTSTLTANAIVAAFSLTMLRVLGG----
Rv3331|M.tuberculosis_H37Rv LVWVYAAESFPSRLRSMGSSPMLTSTLTANAIVAAFSLTMLRVLGG----
MAB_0365c|M.abscessus_ATCC_199 LVWVYAGESFPARLRSYGASAMLTSDLVANAVVSMYFLTLLTALGG----
Mflv_3055|M.gilvum_PYR-GCK VVWVLLGEMFPNRIRAAALGLAAAGQWTANWVITVSFPELRNFLG-----
Mvan_3472|M.vanbaalenii_PYR-1 VVWVLLGEMFPNRIRAAALGLAAAGQWAANWLITVTFPGLREHLG-----
MMAR_2574|M.marinum_M AAYLTVSEIFPMETRALAIAFFYAVGTAIGGISGPLLFGQLIESGQRSQV
MUL_3187|M.ulcerans_Agy99 AAYLTVSEIFPMETRALAIAFFYAVGTAIGGISGPLLFGQLIESGQRSQV
MAV_3053|M.avium_104 AAYLTVSEIFPMETRALAIAFFYAMGTAIGGITGPLLFGQLIDSGQRDHV
MSMEG_4078|M.smegmatis_MC2_155 LVWIYPNELFPTEFRATAVGLTTGISRFGAATGTYLLPLSISTLGVG---
TH_3722|M.thermoresistible__bu VAVVTAVEQFTTRVRYSGMSVGYNVCVALFGGTTPYVMTWLIDTTAN---
MLBr_00430|M.leprae_Br4923 SSRALLLHMAKHGREGVAFGLYTMTGRAASFVAPWSFSIFVDGFGVVR--
. . . .
Mb3364|M.bovis_AF2122/97 AGVFAVFGTFAVVAFVVVYRFAPETKGRKLEEIRHFWENGGRWPAERSPA
Rv3331|M.tuberculosis_H37Rv AGVFAVFGTFAVVAFVVVYRFAPETKGRKLEEIRHFWENGGRWPAERSPA
MAB_0365c|M.abscessus_ATCC_199 VVAFGVFGVLATAALVFVHVLAPETKGRNLEEIRHFWESGGTWPET----
Mflv_3055|M.gilvum_PYR-GCK -AAYGFYALCAVLSGLFVWKWVRETKGVSLEDMHGEILHGDKSATG----
Mvan_3472|M.vanbaalenii_PYR-1 -LAYGFYGLCAVLSGLFVWRWVMETKGVSLEDMHGEILHADKTATG----
MMAR_2574|M.marinum_M FWSFIIGAAVMAVAGLVELWLGIAAEQRPLEELALPLTVADAEDDDEPAD
MUL_3187|M.ulcerans_Agy99 FWSFIIGAAVMAVAGLVELWLGIAAEQRPLEELALPLTVVDAEDDDEPAD
MAV_3053|M.avium_104 VWSFLIGAVVMAAAGLVELWLGIAAEQRPLEDLALPLTVDDAEDTEPQGD
MSMEG_4078|M.smegmatis_MC2_155 -ITMLFGAILTAAAFATCALLATETKDRSLEEASAIEASPTTPSRSERTP
TH_3722|M.thermoresistible__bu PLAPACAVTLAAVVSLGVVMTLRETAARPLAGTP----------------
MLBr_00430|M.leprae_Br4923 --AGLGGISVVLLAGLLGMLMVRVPTRREAAAVGLSWWRSQARRGQV---
.
Mb3364|M.bovis_AF2122/97 ADEP--------
Rv3331|M.tuberculosis_H37Rv ADEP--------
MAB_0365c|M.abscessus_ATCC_199 ------------
Mflv_3055|M.gilvum_PYR-GCK ------------
Mvan_3472|M.vanbaalenii_PYR-1 ------------
MMAR_2574|M.marinum_M GAGARGAQHPGS
MUL_3187|M.ulcerans_Agy99 GAGARGAQHPGS
MAV_3053|M.avium_104 SAPVD-------
MSMEG_4078|M.smegmatis_MC2_155 DKRSVV------
TH_3722|M.thermoresistible__bu ------------
MLBr_00430|M.leprae_Br4923 ------------