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MSSGVQTGTITTQVPSRLDRLPWSRFHWRVVLGLGGVWILDGLEVTMVGNVASRLTESGSGIELSAGQIG IAAAVYITGACLGALFFGQLTDRFGRKKLFLLTLAVYLVATVATAFAFAPWFFFVCRFFTGAGIGGEYAA INSAIDELIPARVRGRVDLIINGSYWLGAAGGALGALLLLNTAIFPADIGWRIAFGIGAVFGLVVLVVRR HVPESPRWLFIHGQEDEAERVVGEIEREVERSTGRPLDEPEGSLTVRQRKTISFVEIAKVAFTKYPKRAV LGLALFIGQAFIYNAFTFNLGTLLSGFFDVASGAVPIFYAVWALSNFAGPILLGRLFDTVGRKPMIALAY LGSAAVAVILTVLFVNEIGGVWLFMLVLGVCFFLASSGASAAYLTVSEIFPMETRALAIAFFYAIGTAVG GITGPLLFGQLIESGERGLVAVSFLIGAAVMAVGGVVELILGVKAEGQKLEDLAMPLTADEGDGESGGDA ENADDQADERARARKEREARIAARVERQRAAQSRARRYRPGPPPGWEGAWREPPTPGVPESALDHEIDAI ARAVADNESMTVRELHRAVGAQYWGPGEFRKALREALAENRIARKARGRVGPPSGMAEPGTPNR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3536 | - | - | 100% (624) | sugar transport protein |
| M. smegmatis MC2 155 | MSMEG_2966 | - | 1e-37 | 27.86% (499) | major facilitator family protein transporter |
| M. smegmatis MC2 155 | MSMEG_4078 | - | 4e-37 | 28.57% (469) | metabolite transport protein YaaU |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3503c | kgtP | 2e-18 | 26.10% (410) | dicarboxylic acid transport integral membrane protein KgtP |
| M. gilvum PYR-GCK | Mflv_0953 | - | 1e-18 | 24.25% (400) | general substrate transporter |
| M. tuberculosis H37Rv | Rv3476c | kgtP | 7e-18 | 25.85% (410) | dicarboxylic acid transport integral membrane protein KgtP |
| M. leprae Br4923 | MLBr_01562 | - | 6e-08 | 26.34% (205) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_3808c | - | 8e-21 | 25.91% (386) | dicarboxylic acid transport integral membrane protein KgtP |
| M. marinum M | MMAR_2574 | - | 0.0 | 72.95% (499) | sugar transporter |
| M. avium 104 | MAV_3053 | - | 0.0 | 73.39% (496) | sugar transport protein |
| M. thermoresistible (build 8) | TH_3722 | - | 6e-20 | 24.88% (422) | PUTATIVE General substrate transporter |
| M. ulcerans Agy99 | MUL_3187 | - | 0.0 | 72.71% (469) | sugar transporter |
| M. vanbaalenii PYR-1 | Mvan_5839 | - | 3e-19 | 25.38% (398) | general substrate transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2574|M.marinum_M ------------------------MSARAQTGTISTHVPARLDRLPWGRF
MUL_3187|M.ulcerans_Agy99 --------------------------------------------------
MAV_3053|M.avium_104 ------------------------MSAGAQTNTITTHVPARLDRLPWSRF
MSMEG_3536|M.smegmatis_MC2_155 ------------------------MSSGVQTGTITTQVPSRLDRLPWSRF
Mb3503c|M.bovis_AF2122/97 --------------------------MTVSIAPPSRPS-QAETRRAIWNT
Rv3476c|M.tuberculosis_H37Rv --------------------------MTVSIAPPSRPS-QAETRRAIWNT
MAB_3808c|M.abscessus_ATCC_199 --------------------------MAVSAADTSTPSGRAQTRRAIWNT
Mflv_0953|M.gilvum_PYR-GCK ---------------------------MDSRDARPPTIEKEQPPAVLKKA
Mvan_5839|M.vanbaalenii_PYR-1 --------------------------------MGMPTTHEDPPPGVLKKA
TH_3722|M.thermoresistible__bu ----------------------------VSENPSIVSAPPAPDAVVIRKA
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
MMAR_2574|M.marinum_M HWRVVIGLGGVWVLDGLEVTMVGNVSARLTEHGSGINLTPAQIGVAASFY
MUL_3187|M.ulcerans_Agy99 ----MIGLGGVWVLDGLEVTMVGNVSARLTEHGSGINLTPAQIGVAASFY
MAV_3053|M.avium_104 HWRVVIGLGGVWVLDGLEVTMVGNVSARLMEPGSGIALNPAQIGMAAAIY
MSMEG_3536|M.smegmatis_MC2_155 HWRVVLGLGGVWILDGLEVTMVGNVASRLTESGSGIELSAGQIGIAAAVY
Mb3503c|M.bovis_AF2122/97 IRG-SSGNLVEWYDVYVYTVFATYFEDQFFDR-ADRNSTVYVYAIFAVTF
Rv3476c|M.tuberculosis_H37Rv IRG-SSGNLVEWYDVYVYTVFATYFEDQFFDR-ADRNSTVYVYAIFAVTF
MAB_3808c|M.abscessus_ATCC_199 IRG-SSGNLVEWYDVYVYTVFAMYFEKQFFDD-SDQNSTVYVYAIFAVTF
Mflv_0953|M.gilvum_PYR-GCK IAASAIGNATEWFDYGIYAYGVTYISAAIFPG-DAANATLLALMTFAVSF
Mvan_5839|M.vanbaalenii_PYR-1 ISASAIGNATEWFDYGIYAYGVSYISAAIFPG-DAANATLLALMTFAVSF
TH_3722|M.thermoresistible__bu VTGASIGNAVEWFDFAIYGFLATYIAANFFPAGDDTAALLNTFAIFAAAF
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA
. : . .
MMAR_2574|M.marinum_M IAGACLGALFFG-HLTDRFGRRNLFLLTLAVYLTATVATAFA--------
MUL_3187|M.ulcerans_Agy99 IAGACLGALFFG-HLTDRFGRRNLFLLTLAVYLTATVATAFA--------
MAV_3053|M.avium_104 IAGACSGALFFG-HLTDRFGRRNLFILTLALYLIATVATAFA--------
MSMEG_3536|M.smegmatis_MC2_155 ITGACLGALFFG-QLTDRFGRKKLFLLTLAVYLVATVATAFA--------
Mb3503c|M.bovis_AF2122/97 VTRP-VGSWFFG-RFADRRGRRAALTFSVSLMAACSLIVALVPSRSSIGV
Rv3476c|M.tuberculosis_H37Rv VTRP-VGSWFLG-RFADRRGRRAALTFSVSLMAACSLIVALVPSRSSIGV
MAB_3808c|M.abscessus_ATCC_199 ITRP-LGSWFFG-RFADRNGRRAALTLSVSLMAACSMVIALVPSRGSIGM
Mflv_0953|M.gilvum_PYR-GCK LVRP-LGGFVWG-PLGDRLGRKRVLAMTILLMAGATFCVGLVPTYAAIGM
Mvan_5839|M.vanbaalenii_PYR-1 LVRP-LGGFVWG-PLGDRLGRKRVLAITIVLMAGATFCVALVPTYDMIGM
TH_3722|M.thermoresistible__bu VVRP-LGGFFFG-PLGDRIGRQRVLALVILLMSGATLTMGLLPTYESIGV
MLBr_01562|M.leprae_Br4923 YVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVA--------
. . * . * : * **: : . : : .:. ..
MMAR_2574|M.marinum_M FAPWYFFIARFFTGSGIGGEYAAINSAIDELIPARVRGRVDLIINGTYWL
MUL_3187|M.ulcerans_Agy99 FAPWYFFIARFFTGSGIGGEYAAINSAIDELIPARVRGRVDLIINGTYWL
MAV_3053|M.avium_104 FAPWYFFLTRFFTGAGIGGEYAAINSAIDELIPARVRGRVDLVINGTYWL
MSMEG_3536|M.smegmatis_MC2_155 FAPWFFFVCRFFTGAGIGGEYAAINSAIDELIPARVRGRVDLIINGSYWL
Mb3503c|M.bovis_AF2122/97 AAPILLILCRLVQGFATGGEYGTSVTYMSEAATRERRGYFSSFQYVTLVG
Rv3476c|M.tuberculosis_H37Rv AAPILLILCRLVQGFATGGEYGTSATYMSEAATRERRGYFSSFQYVTLVG
MAB_3808c|M.abscessus_ATCC_199 AAPIVLILCRLVQGFATGGEYGTSATYMSEAATRERRGFFSSFQYVTLVG
Mflv_0953|M.gilvum_PYR-GCK WAPFLLVLLRMIQGFSTGGEYGGAATFMAEYSPSRRRGLLGSFLEFGTLA
Mvan_5839|M.vanbaalenii_PYR-1 WAPFLLVLLRMIQGFSTGGEYGGAATFMAEYAPNRRRGLLGSFLEFGTLG
TH_3722|M.thermoresistible__bu LAPLLLLLLRCLQGFSAGGEYGGGAVYLAEFAPDRRRGLIVTFMAWSGVL
MLBr_01562|M.leprae_Br4923 WDEVTLVIARLLQGIGS---AIASPTGLALVATTFSKGSARNTATAVFAA
:.: * . * . : . :*
MMAR_2574|M.marinum_M GSAAGAAGALVLLDTSN--FAPNMGWRLAFGLGAIFGIFVLLVRRNVPES
MUL_3187|M.ulcerans_Agy99 GSAAGAAGALVLLDTSN--FAPNMGWRLAFGLGAIFGIFVLLVRRNVPES
MAV_3053|M.avium_104 GSAAGAGGALILLDTSN--FAADLGWRLAFGIGAILGIFVLLVRRNVPES
MSMEG_3536|M.smegmatis_MC2_155 GAAGGALGALLLLNTAI--FPADIGWRIAFGIGAVFGLVVLVVRRHVPES
Mb3503c|M.bovis_AF2122/97 GHVLAQFTLLVILAVFTREQVHEFGWRIGFAVGGGAAIVVFWLRRTMDES
Rv3476c|M.tuberculosis_H37Rv GHVLAQFTLLVILAVFTREQVHEFGWRIGFAVGGGAAIVVFWLRRTMDES
MAB_3808c|M.abscessus_ATCC_199 GHVLAQFTLLIILTVFDTAQVHEFGWRIAFATGGVAAIVVYWLRRTMDES
Mflv_0953|M.gilvum_PYR-GCK GFSCGALLMLGCSLVLGDEDMQAWGWRLPFLVAAPLGLIGVYLRSRLEDT
Mvan_5839|M.vanbaalenii_PYR-1 GFSLGALLMLGCSLVLGDEQMHAWGWRLPFLVAAPLGLIGLYLRSRLEDT
TH_3722|M.thermoresistible__bu GFLLGSVTVTALQVALPDQVMTDVGWRIPFLLAGPLGLIGLYIRLRLDDT
MLBr_01562|M.leprae_Br4923 MTAIGSVMGLVVGGALT-----EVSWRLAFLVNVPIGLVMIYLARTALHE
. . .**: * .:. : .
MMAR_2574|M.marinum_M PRWLFIHGREQEAEQIVREIEEEVERDTGQRLPDPPGRPLK---------
MUL_3187|M.ulcerans_Agy99 PRWLFIHGREQEAEQIVREIEEEVERDTGQRLPDPPGRPLK---------
MAV_3053|M.avium_104 PRWLFIHGREEEAEHIVGEIEEAVQQQTGRPLPEPQGKALR---------
MSMEG_3536|M.smegmatis_MC2_155 PRWLFIHGQEDEAERVVGEIEREVERSTGRPLDEPEG-SLT---------
Mb3503c|M.bovis_AF2122/97 LSQERLTAIKAGRDHDSGSLRELATH------------------------
Rv3476c|M.tuberculosis_H37Rv LSQERLTAIKAGRDHDSGSLRELATH------------------------
MAB_3808c|M.abscessus_ATCC_199 LSEEQLAAIKAGADTSSGSMRELLTR------------------------
Mflv_0953|M.gilvum_PYR-GCK PVYRELEQEGRTEESTSMQFRDLVVR------------------------
Mvan_5839|M.vanbaalenii_PYR-1 PVFRELEAKGGTEPETTTQFRDLLGR------------------------
TH_3722|M.thermoresistible__bu PAFTALSEQ---EEVAQSPLREAVQT------------------------
MLBr_01562|M.leprae_Br4923 THKERMKLDAAGAILATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVA
:
MMAR_2574|M.marinum_M ---IRQRQRISLWEIARVAFTRYPRRAFLGLALFIGQAFLYNGVTFNLGT
MUL_3187|M.ulcerans_Agy99 ---IRQRQRISLWEIARVAFTRYPRRAFLGLALFIGQAFLYNGVTFNLGT
MAV_3053|M.avium_104 ---IRQRTAISFREIAAVAFKLYPRRAVLGLALFIGQAFLYNGVTFNLGT
MSMEG_3536|M.smegmatis_MC2_155 ---VRQRKTISFVEIAKVAFTKYPKRAVLGLALFIGQAFIYNAFTFNLGT
Mb3503c|M.bovis_AF2122/97 ----------------------YWKPLLLCFLVTLGGTVAFYTYSVNAPA
Rv3476c|M.tuberculosis_H37Rv ----------------------YWKPLLLCFLVTLGGTVAFYTYSVNAPA
MAB_3808c|M.abscessus_ATCC_199 ----------------------YRKPLLLCFLITMGGTLAFYTYSVNAPA
Mflv_0953|M.gilvum_PYR-GCK ----------------------YWRPILQMGGLVVALNVVNYTLLTYMPT
Mvan_5839|M.vanbaalenii_PYR-1 ----------------------YWRPILQLGGLVVALNVVNYTLLSYMPT
TH_3722|M.thermoresistible__bu ----------------------AWRSILQVIGLMIIFNVAYYVVFAYMPT
MLBr_01562|M.leprae_Br4923 AIAFAVVERTAENPVVPFDLFRDRNRLVTFIAIFLAGGVIFS-LTVSIGL
. . : : .
MMAR_2574|M.marinum_M LLSGFYGVESGHVPLFFIVWALSNFVGPLVLGRLFDTVGRKPMITMSYIG
MUL_3187|M.ulcerans_Agy99 LLSGFYGVESGHVPLFFIVWALSNFVGPLVLGRLFDTVGRKPMITMSYIG
MAV_3053|M.avium_104 LLSQFYAVPSGMVPVFFVLWALSNFAGPLLLGHLFDTVGRKQMITLTYIG
MSMEG_3536|M.smegmatis_MC2_155 LLSGFFDVASGAVPIFYAVWALSNFAGPILLGRLFDTVGRKPMIALAYLG
Mb3503c|M.bovis_AF2122/97 IVKSVYGSQAMTATWINLVGLILLMMLQPIGGMISDKIGRKPLLLWFGVG
Rv3476c|M.tuberculosis_H37Rv IVKSVYGSQAMTATWINLVGLILLMMLQPIGGMISDKIGRKPLLLWFGVG
MAB_3808c|M.abscessus_ATCC_199 IVKAAYKDQAMTATWINLAGLIFLMLLQPVGGIISDKVGRKPLLLFFGFG
Mflv_0953|M.gilvum_PYR-GCK YLENSIGLSADQSLMVPIIGMLAMMVFVPFAGLLSDRVGRKPLWWFSLIG
Mvan_5839|M.vanbaalenii_PYR-1 YLENRIGLSPDQSLIVPVIGMLSMMVFVPFAGLLSDRVGRKPLWWFSLIG
TH_3722|M.thermoresistible__bu YLIKELGLSSSDAFISSTIACVVALVLILPLAALSDRIGRKPLLVGGAIA
MLBr_01562|M.leprae_Br4923 YIQDILGYSALRAGIGFIPFVIAMGIGLGVSSQLVSRFS--PRVLTIGGG
: . : . : . .. .
MMAR_2574|M.marinum_M SAVIAVVLAVIFVNQTGGVWTFIIVLAAAFFLASAGASAAYLTVSEIFPM
MUL_3187|M.ulcerans_Agy99 SAVIAVVLAVIFVNQTGGVWTFIIVLAAAFFLASAGASAAYLTVSEIFPM
MAV_3053|M.avium_104 SAVVVVALALVFLTQAGGVWAFIGVLIVAFFLASAGASAAYLTVSEIFPM
MSMEG_3536|M.smegmatis_MC2_155 SAAVAVILTVLFVNEIGGVWLFMLVLGVCFFLASSGASAAYLTVSEIFPM
Mb3503c|M.bovis_AF2122/97 GLIYTYVLVTYLP-ETRSPTMSFLLVAVGYVILTGYCSINALVKSELFPA
Rv3476c|M.tuberculosis_H37Rv GLIYTYVLVTYLP-ETRSPTMSFLLVAVGYVILTGYCSINALVKSELFPA
MAB_3808c|M.abscessus_ATCC_199 GVVYTYVLITYLP-QVHAPIVSFLLVAVSYVLLTGYTSINALVKSELFPS
Mflv_0953|M.gilvum_PYR-GCK -LFVAGIPAFLLM-GTN-LAGAVIGFAILGLLYVPQLATISATFPAMFPT
Mvan_5839|M.vanbaalenii_PYR-1 -LFVAGVPMFLLM-GTN-LWGAVIGFAVLGLLYVPQLATISATFPAMFPT
TH_3722|M.thermoresistible__bu -FAVLAYPLFLLL-NSGSTAAAMIAHAGLAAIESVVISVAVVTAVEQFTT
MLBr_01562|M.leprae_Br4923 WLLMVAMLYGWAFMNRGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGV
: .
MMAR_2574|M.marinum_M ETRALAIAFFYAVGTAIGGISGPLLFGQLIESGQRSQVFWSFIIGAAVMA
MUL_3187|M.ulcerans_Agy99 ETRALAIAFFYAVGTAIGGISGPLLFGQLIESGQRSQVFWSFIIGAAVMA
MAV_3053|M.avium_104 ETRALAIAFFYAMGTAIGGITGPLLFGQLIDSGQRDHVVWSFLIGAVVMA
MSMEG_3536|M.smegmatis_MC2_155 ETRALAIAFFYAIGTAVGGITGPLLFGQLIESGERGLVAVSFLIGAAVMA
Mb3503c|M.bovis_AF2122/97 HVRALGVGVGYALANSVFGGTAPLIYQALKERDQVPMFIAYVTACIAVSL
Rv3476c|M.tuberculosis_H37Rv HVRALGVGVGYALANSVFGGTAPLIYQALKERDQVPMFIAYVTACIAVSL
MAB_3808c|M.abscessus_ATCC_199 HVRALGVGVGYALANSVFGGTAPLIYQALKEHDQVPLFIGYVTVCIAISL
Mflv_0953|M.gilvum_PYR-GCK QVRYAGFAIAYNVSTSIFGGTAPAVNDWLVGATGDNLVPAYYMMGACVIG
Mvan_5839|M.vanbaalenii_PYR-1 QVRYAGFAIAYNVSTSLFGGTAPAINQWLTGETGDLLFPAYYMMGACVIG
TH_3722|M.thermoresistible__bu RVRYSGMSVGYNVCVALFGGTTPYVMTWLIDTTANPLAPACAVTLAAVVS
MLBr_01562|M.leprae_Br4923 GFDRIGPVSAIALMLQSLGGPLVLAVIQAVITS-RTLYLGGTTGPVKFMN
. : * . .
MMAR_2574|M.marinum_M VAGLVELWLGIAAEQRPLEELALPLTVA--------DAEDDDEPADG-AG
MUL_3187|M.ulcerans_Agy99 VAGLVELWLGIAAEQRPLEELALPLTVV--------DAEDDDEPADG-AG
MAV_3053|M.avium_104 AAGLVELWLGIAAEQRPLEDLALPLTVD--------DAEDTEPQGDS-AP
MSMEG_3536|M.smegmatis_MC2_155 VGGVVELILGVKAEGQKLEDLAMPLTADEGDGESGGDAENADDQADERAR
Mb3503c|M.bovis_AF2122/97 IVYVFFIKNKADTYLDREQGFAFYGHA-----------------------
Rv3476c|M.tuberculosis_H37Rv IVYVFFIKNKADTYLDREQGFAFYGHA-----------------------
MAB_3808c|M.abscessus_ATCC_199 VVYLFFLKNKSQTYLDREQGSAFNR-------------------------
Mflv_0953|M.gilvum_PYR-GCK ALALIRIPETTRCPLNGTATPGTDEAPAP--------VEYEKSSA-----
Mvan_5839|M.vanbaalenii_PYR-1 AIALIKVPETARCPIGGTVTPGTEEAADP--------VPFEKQNA-----
TH_3722|M.thermoresistible__bu LGVVMTLRETAARPLAGTP-------------------------------
MLBr_01562|M.leprae_Br4923 DAQLRALDHGYTYGLLWVAGAVVIVGVAALFIGYTPEQVAYAQEVKEAVD
: :
MMAR_2574|M.marinum_M ARGAQHPGS-----------------------------------------
MUL_3187|M.ulcerans_Agy99 ARGAQHPGS-----------------------------------------
MAV_3053|M.avium_104 VD------------------------------------------------
MSMEG_3536|M.smegmatis_MC2_155 ARKEREARIAARVERQRAAQSRARRYRPGPPPGWEGAWREPPTPGVPESA
Mb3503c|M.bovis_AF2122/97 --------------------------------------------------
Rv3476c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3808c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0953|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5839|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3722|M.thermoresistible__bu --------------------------------------------------
MLBr_01562|M.leprae_Br4923 AGEL----------------------------------------------
MMAR_2574|M.marinum_M --------------------------------------------------
MUL_3187|M.ulcerans_Agy99 --------------------------------------------------
MAV_3053|M.avium_104 --------------------------------------------------
MSMEG_3536|M.smegmatis_MC2_155 LDHEIDAIARAVADNESMTVRELHRAVGAQYWGPGEFRKALREALAENRI
Mb3503c|M.bovis_AF2122/97 --------------------------------------------------
Rv3476c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3808c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0953|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5839|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3722|M.thermoresistible__bu --------------------------------------------------
MLBr_01562|M.leprae_Br4923 --------------------------------------------------
MMAR_2574|M.marinum_M ----------------------
MUL_3187|M.ulcerans_Agy99 ----------------------
MAV_3053|M.avium_104 ----------------------
MSMEG_3536|M.smegmatis_MC2_155 ARKARGRVGPPSGMAEPGTPNR
Mb3503c|M.bovis_AF2122/97 ----------------------
Rv3476c|M.tuberculosis_H37Rv ----------------------
MAB_3808c|M.abscessus_ATCC_199 ----------------------
Mflv_0953|M.gilvum_PYR-GCK ----------------------
Mvan_5839|M.vanbaalenii_PYR-1 ----------------------
TH_3722|M.thermoresistible__bu ----------------------
MLBr_01562|M.leprae_Br4923 ----------------------