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MTSAHPFRRNTPELSRRDAIRRAGLLGIGASGLAALLAACGLGRDDTDPPATTAPAGGHTRQIFADRMYV LDGGTAHVTDISQWSPGVNEGQSATFSNNVYLIEHGDEWMVWDTGLDENLIDVPGGEVVAHDVRGVVTRR LSDQFSELGVDPAAVNHIAFSHAHFDHVGNSRMFPSATWYVQRDEHAAMFGDSFADYGFIPDLYATMADN PTVLLDGDHDVFGDGTVVVLDTAGHTPGHQSLLVHLRGAGTLLLSGDVAHFCDNFRHRRVPTFNADHDRS RASMDRVDELIRTENATLLINHDARQNALIRQAPHAIE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3925 | - | - | 100% (318) | AttM/AiiB family protein |
| M. smegmatis MC2 155 | MSMEG_6679 | - | 2e-12 | 29.82% (218) | metallo-beta-lactamase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3311 | - | 5e-05 | 42.86% (42) | dienelactone hydrolase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4947 | - | 1e-07 | 27.08% (240) | Beta-lactamase-like protein |
| M. marinum M | MMAR_3523 | - | 1e-07 | 25.29% (257) | hypothetical protein MMAR_3523 |
| M. avium 104 | MAV_2782 | - | 6e-05 | 28.57% (147) | metallo-beta-lactamase |
| M. thermoresistible (build 8) | TH_0195 | - | 1e-06 | 25.56% (223) | metal dependent hydrolase |
| M. ulcerans Agy99 | MUL_2742 | - | 6e-07 | 26.05% (238) | hypothetical protein MUL_2742 |
| M. vanbaalenii PYR-1 | Mvan_2949 | - | 4e-07 | 27.19% (217) | beta-lactamase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
TH_0195|M.thermoresistible__bu ---------------------------------MSTTAVRPVAHPEHDEL
Mvan_2949|M.vanbaalenii_PYR-1 ---------------------------------MSLDGISRLGGQSTDEL
MMAR_3523|M.marinum_M --------------------------------------------------
MUL_2742|M.ulcerans_Agy99 --------------------------------------------------
MAB_4947|M.abscessus_ATCC_1997 -----------------------------------MFSAAVRTFTVGDAT
MSMEG_3925|M.smegmatis_MC2_155 MTSAHPFRRNTPELSRRDAIRRAGLLGIGASGLAALLAACGLGRDDTDPP
MAV_2782|M.avium_104 --------------------------------------------------
Mflv_3311|M.gilvum_PYR-GCK --------------------------------------MTPLQRYIAEEI
TH_0195|M.thermoresistible__bu VPSR----YALRVGDIEVLVISDGVLPLPAATLATNADRAELAAWLHDMF
Mvan_2949|M.vanbaalenii_PYR-1 VPSR----YVQQVGEIEVTVICDGVLPITASTLATNADPAELAGWLDDMF
MMAR_3523|M.marinum_M ---------------MKVHHLNCGTMNSPGAALLCHVLLVEAG---NGLV
MUL_2742|M.ulcerans_Agy99 ---------------MKVHHHNCGTMNSPGAALLCHVLLVEAG---NGLV
MAB_4947|M.abscessus_ATCC_1997 VTQL----TELDVWPIKPHHWYPALSEEQLVFARANYAPSAVSDDGSELI
MSMEG_3925|M.smegmatis_MC2_155 ATTAPAGGHTRQIFADRMYVLDGGTAHVTDISQWSPGVNEGQSATFSNNV
MAV_2782|M.avium_104 --------------------MHLAWERLTGSVHRCRLP------------
Mflv_3311|M.gilvum_PYR-GCK ATDHVDGLMSRREALRRLALLGVGGAAATALIAACGQNQQS---------
.
TH_0195|M.thermoresistible__bu LPADLFDWPLNVAVVRSGDRTILIDSGLGLEFPEFPRAGRLAHRMQAAGI
Mvan_2949|M.vanbaalenii_PYR-1 LPPDVLDWPLNVVVVRTGGQTILVDAGLGVEFPDFPRAGQTVRRLEAAGI
MMAR_3523|M.marinum_M LVDTGFGVQDCLDPRRLGAFRHFLR-------PALLQNETAVHQIERLGY
MUL_2742|M.ulcerans_Agy99 LVDTGFGVQDCLDQRRLGAFRHFLR-------PALLQNETAVHQIERLGY
MAB_4947|M.abscessus_ATCC_1997 FAIHNYVIELADTIIVVDTCSGNHKNR-PLFADLHMLNTDYLTRLEQSGY
MSMEG_3925|M.smegmatis_MC2_155 YLIEHGDEWMVWDTGLDENLIDVPGGEVVAHDVRGVVTRRLSDQFSELGV
MAV_2782|M.avium_104 ----FCDVTVGLICGRSGTLLVDTG-------TTLTEAAAIDADVHRLAR
Mflv_3311|M.gilvum_PYR-GCK -AETTAEPSPTSDTPTSDAPPPGMDAALPTEPVTWAGPKGELQGAWAQAA
.
TH_0195|M.thermoresistible__bu EPAAVTDVVLTHLHMDHVGG--LLTDGLMGRLRPDLRVHLAAAEAE-FWA
Mvan_2949|M.vanbaalenii_PYR-1 DPASVTDVVLTHLHMDHVGG--LLTDGLKARLRPDLRIHLAAAEAE-FWA
MMAR_3523|M.marinum_M RPSDVRHVVLTHFDFDHIGG--LAD-------FPDAQVHVTSAEARGAIH
MUL_2742|M.ulcerans_Agy99 RPSDVRHIVLTHFDSDHIGG--LAD-------FPDAQVHVTSAEARGAIH
MAB_4947|M.abscessus_ATCC_1997 SPEAVDIVVNTHLHLDHCGWNTRLVEGTWRPTFPAATYLFHHTELKYIRA
MSMEG_3925|M.smegmatis_MC2_155 DPAAVNHIAFSHAHFDHVGN---------SRMFPSATWYVQRDEHAAMFG
MAV_2782|M.avium_104 RP--VSHIALTHKHFDHVLG---------SSLFTGAEVYCAPEVVEYLGA
Mflv_3311|M.gilvum_PYR-GCK EPRGGILVIHENKGLNDWTRSVAGRLAGAGYSSLAIDLLSERGGTATFAD
* : : :.
TH_0195|M.thermoresistible__bu APDFSRTAMPHPVPDVL--RAVASRFLDVYRDRLRPFDTQYEVAPG-VSV
Mvan_2949|M.vanbaalenii_PYR-1 APDFSQTAMPQPVPDVL--RSVATRFLDEYHGRLRPFETEYEVAPG-VLI
MMAR_3523|M.marinum_M APSFRERVRYRSVQWAHGPKLVEHGHDGESWRGFAAAKPLDAIADG-VVL
MUL_2742|M.ulcerans_Agy99 APSFRERVRYRSVQWAHGPKLVEHGHDGESSPGFAAAKTLDAIADG-VVL
MAB_4947|M.abscessus_ATCC_1997 QWESAPIDQWQDNGGWVYEDSILPVLEHAPYGFVKSGQVLHSYGSTHIRA
MSMEG_3925|M.smegmatis_MC2_155 DSFADYGFIPDLYATMADNPTVLLDGDHDVFG------------DGTVVV
MAV_2782|M.avium_104 ATDQIRDDALRHGADAAEVDAAIAALRPGQHG---IRDARIDLGDRTVTI
Mflv_3311|M.gilvum_PYR-GCK PAEATAALGARTPEDMVADLRSGIAEVQRRTPDKKVAAIGFCMGGGLVWR
:
TH_0195|M.thermoresistible__bu HRTGG-HTPGHSIVRLES---GKDRLTFAGDAVFQVGFDNPQWHNGFEHD
Mvan_2949|M.vanbaalenii_PYR-1 SRTGG-HTPGHSIVRVAS---GGEALTFAGDAVFAPGFDNPEWHNGFEHD
MMAR_3523|M.marinum_M VPMPG-HTRGHAAVAVDA---GDRWILHCGDAFYHVGTLDGQSKVPFVLR
MUL_2742|M.ulcerans_Agy99 VPMPG-HTRGHAAVAVDA---GDRWILHCGDAFYHVGTLDGQSKVPFVLR
MAB_4947|M.abscessus_ATCC_1997 LDAGG-HTPGHVAIEVRA---ADTGLLIAGDALHHPMQAQFPDLPFYADA
MSMEG_3925|M.smegmatis_MC2_155 LDTAG-HTPGHQSLLVHLR--GAGTLLLSGDVAHFCDNFRHRRVPTFNAD
MAV_2782|M.avium_104 THLGAGHTASDLAVIVPAARDGEPTVVFTGDLVEESGD------PAIDAD
Mflv_3311|M.gilvum_PYR-GCK LLAAG---TPELAAAFPFYGPTPEAPDFAGSRDVAVLAFYGELDQRVNAT
. . . *.
TH_0195|M.thermoresistible__bu P-EEAARVRVR-----LLQEIAASGETLVATHLPFPSLCRVAPRGEAFRF
Mvan_2949|M.vanbaalenii_PYR-1 P-EEAARVRVR-----LLRELAATGEALVATHLPFPSVCRVATAGDVFRC
MMAR_3523|M.marinum_M SQEELFSFDRR-----QLRDNQARLAELQRRQD--PGLLIICAHDPSLYA
MUL_2742|M.ulcerans_Agy99 SQEELFSFDRR-----QLRDNQARLAELQRRQD--PGLLIICAHDPSLYA
MAB_4947|M.abscessus_ATCC_1997 DPAQAVATRRA-----LLGRCADENLKLLTAHFPAHSPLGVRRSGAAFTW
MSMEG_3925|M.smegmatis_MC2_155 HDRSRASMDRV-----DELIRTENATLLINHDARQNALIRQAPHAIE---
MAV_2782|M.avium_104 SDVTAWPATLD-----RLLALGGPGARYVPGHGRVVDAAFVRRQRDWLRA
Mflv_3311|M.gilvum_PYR-GCK EPDARAALEKAGLVHEIVIEPGANHAFFNDTGDRYDPAAAADAWERTLAW
TH_0195|M.thermoresistible__bu VPTVWDH
Mvan_2949|M.vanbaalenii_PYR-1 VPSVWDY
MMAR_3523|M.marinum_M LAKDLS-
MUL_2742|M.ulcerans_Agy99 VAKDLS-
MAB_4947|M.abscessus_ATCC_1997 DGSRAID
MSMEG_3925|M.smegmatis_MC2_155 -------
MAV_2782|M.avium_104 RAATR--
Mflv_3311|M.gilvum_PYR-GCK LTAHVG-