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LRKMGFLTIGRFDTADPGPGHEETLRMIERAEALGFDTVWVRQRHLQPGISSPVAILAAASQRTSRIELG TAVIPLGLENPLRLAEDLATVDILSGGRLNPGVSVGTPMHYDNYRTALYPETHAVENFTKDRVTRLLAGL RGDPVSSFEGTIGIERFSRSVQPHAPGLAERVWYGGGLASAIWAGTQGLNYLTSNVVSTEGTISRDFGTI QAEQIDAFLAHHPNPATARVSQGLVVIPTDSATSAQVHKYRAYATARLERTRTTHGPRGMMFAPDLVGTT DELAEMLYEHPGFQRAREVAFALPFTFDEEDYVQIVTDMAEKLGPKLGWTAAEA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3583 | - | - | 100% (334) | monooxygenase |
| M. smegmatis MC2 155 | MSMEG_4092 | - | 8e-27 | 29.91% (331) | alkanal monooxygenase |
| M. smegmatis MC2 155 | MSMEG_1475 | - | 7e-12 | 25.52% (290) | hypothetical protein MSMEG_1475 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3550c | - | 1e-06 | 32.33% (133) | coenzyme F420-dependent oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4544 | - | 2e-10 | 31.21% (173) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3618 | - | 3e-07 | 31.97% (122) | monooxygenase |
| M. leprae Br4923 | MLBr_00348 | - | 6e-06 | 30.25% (119) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_4628c | - | 8e-11 | 26.91% (249) | luciferase-like monooxygenase |
| M. marinum M | MMAR_2824 | - | 7e-15 | 39.67% (121) | monooxygenase |
| M. avium 104 | MAV_2779 | - | 9e-15 | 37.93% (145) | limonene 1,2-monooxygenase |
| M. thermoresistible (build 8) | TH_3375 | - | 3e-13 | 51.28% (78) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2949 | - | 5e-15 | 39.67% (121) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_3368 | - | 6e-11 | 30.29% (175) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2824|M.marinum_M --MANLRFGYFIAPFHRAGTNPTLA-LQRDLEFVEHLDALGFDEAWIGEH
MUL_2949|M.ulcerans_Agy99 --MAKLRFGYFIAPFHRAGTNPTLA-LQRDLEFVEHLDALGFDEAWIGEH
MAV_2779|M.avium_104 --MGKLRFGYFIAPFHRAGTNPTLA-LQRDLEFIEHLDALGFDEVWLGEH
Rv3618|M.tuberculosis_H37Rv -MKAPLRFGVFITPFHPTGQSPTVA-LQYDMERVVALDRLGYDEAWFGEH
Mflv_4544|M.gilvum_PYR-GCK MRIGLSTPVVVQTPAAASPWEAGAG-IGDIARIAETADDLGFDYLTCSEH
Mvan_3368|M.vanbaalenii_PYR-1 ----MSTPVVVQTPAMASPWEGGAD-IEDVARIAEVADSLGFDYLTCSEH
Mb3550c|M.bovis_AF2122/97 -----MEAG--MKLGLQLGYWGAQP-PQNHAELVAAAEDAGFDTVFTAEA
MLBr_00348|M.leprae_Br4923 ----MVERANAMKLGLQLGYWAAQP-PGNAAELVAAAEGAGFDAVFTGEA
MAB_4628c|M.abscessus_ATCC_199 MRFQLLDIVFHLPNPATRALAPAAERLNRVIETAVLAENLGFDSFAVGER
TH_3375|M.thermoresistible__bu -----VGLGALTAQTRSGTAAESTEALTMLLDTCVLAEDEGLDSAWVAEH
MSMEG_3583|M.smegmatis_MC2_155 -----MRKMGFLTIGRFDTADPGPG-HEETLRMIERAEALGFDTVWVRQR
: * * :
MMAR_2824|M.marinum_M HSAGSEIISS-------PEVFIAAAAERTKRIRLGTGVISLAYHNPLWVA
MUL_2949|M.ulcerans_Agy99 HSAGSEIISS-------PEVFIAAAAERTKRIRLGTGVISLAYHNPLWVA
MAV_2779|M.avium_104 HSAGSEIISS-------PEIFIAAAAERAKRIRFGTGVISLSYHNPLWVA
Rv3618|M.tuberculosis_H37Rv HSGGYELIAC-------PEVFIAAAAERTTHIRLGTGVVSLPYHHPLMVA
Mflv_4544|M.gilvum_PYR-GCK VAVPVGDAAVRGATYWDPLATLGFLAARTARIRLATSVLVLGYHHPLEIA
Mvan_3368|M.vanbaalenii_PYR-1 VAVPVDEAGLRGAVYWDPLATLGFLAARTSRIRLATSVLVLGYHHPLEIA
Mb3550c|M.bovis_AF2122/97 WGS-------------DAYTPLAWWGSSTQRVRLGTSVIQLSARTPTACA
MLBr_00348|M.leprae_Br4923 WGS-------------DAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACA
MAB_4628c|M.abscessus_ATCC_199 HAGDVLSSAP--------TVLLGAVAAATDRILLSTGVTVLSLLDPVRAA
TH_3375|M.thermoresistible__bu HFAADGFLSS-------PMTVLAALSQRTSRIRLSTNVMIGPLYDPIRLA
MSMEG_3583|M.smegmatis_MC2_155 HLQPGISS---------PVAILAAASQRTSRIELGTAVIPLGLENPLRLA
:. . : :: :.* * * *
MMAR_2824|M.marinum_M DRLMLLDHLTHGRVIGGMGPGSLPTDSAMIGLTPTDTRELLETNLDIVVR
MUL_2949|M.ulcerans_Agy99 DRLMLLDHLTHGRVIGGMGPGSLATDSAMIGLTPTDTRELLETNLDIVVR
MAV_2779|M.avium_104 DRLMLLDHLTHGRIIGGVGPGSLPTDSSMIGLTPTDTRELLETNLDIVVR
Rv3618|M.tuberculosis_H37Rv DRWVLLDHLTRGRVMFGTGPGALPSDAYMMGIDPVEQRRMMQESLEAILA
Mflv_4544|M.gilvum_PYR-GCK KRYGTLDRVSGGRLILGVGVGSLQPEFDLLG-APWEERGARAD-------
Mvan_3368|M.vanbaalenii_PYR-1 KRYGTLDRVSGGRLVLGVGVGSLRAEFEMLS-APWEDRGVRAD-------
Mb3550c|M.bovis_AF2122/97 MAALTLDHLSGGRHILGLGVSGPQVVEGWYGQRFPKPLARTREYIDIVRQ
MLBr_00348|M.leprae_Br4923 MAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQ
MAB_4628c|M.abscessus_ATCC_199 EDFATIDQLSRGRLEIVIGKGNEDRQYPLMGLDIAKQYEYLQENYELLRR
TH_3375|M.thermoresistible__bu EDAAVVDQLSRGRLMLGLGLGYRDVEFAGLGRRRQERGRRLDDLINVLRQ
MSMEG_3583|M.smegmatis_MC2_155 EDLATVDILSGGRLNPGVSVGTPMHYDNYRTALYPETHAVENFTKDRVTR
:* :: ** . . .
MMAR_2824|M.marinum_M LLAG---QTVTAKTATHQLFDARLQLAPFSEGGIPLAVAAVAS--PTGAR
MUL_2949|M.ulcerans_Agy99 LLAG---QTVTAKTATHQLFDARLQLAPFSEGGIPLAVAAVAS--PTGAR
MAV_2779|M.avium_104 LLAG---ETVSAKTATHQLFDAKLQLGPYSDGGIPLAVAAVAS--PTGAR
Rv3618|M.tuberculosis_H37Rv LFRAAPDERIDRHSDWFTLREAQLHIRPYTWPYPEIATAAMIS--PSGPR
Mflv_4544|M.gilvum_PYR-GCK -------DAIRALRSSLSVAEPSYDGDFYTFGGMVVEPHAEQP--RVPIW
Mvan_3368|M.vanbaalenii_PYR-1 -------DAIRALRSSLSVSAPSYHGEFHRYQAMMVEPHAVQP--RVPIW
Mb3550c|M.bovis_AF2122/97 VWAR---ESPVTSAGPHYRLPLTGEGTTGLGKALKPITHPLRA--DIPIM
MLBr_00348|M.leprae_Br4923 VWAR---EAPVVSDGQHYPLPLTGAGATGLGKALKPITHPLRA--DIPIM
MAB_4628c|M.abscessus_ATCC_199 LLRE---EHVDWVGVHRHPLADATTLPRPYDGPFRIWHGSATS--TFAVE
TH_3375|M.thermoresistible__bu AWSG---KPVEHHGLGTYKTPPVTPLPFQQDGPPVLVGAFAEAGLRRAVR
MSMEG_3583|M.smegmatis_MC2_155 LLAGLRGDPVSSFEGTIGIERFSRSVQPHAPGLAERVWYGGGL--ASAIW
.
MMAR_2824|M.marinum_M LAGRHGIGLLSIGATLTIEGFDALAYHWGIVEERAAAFG-THADRKNWTL
MUL_2949|M.ulcerans_Agy99 LAGRHGIGLLSIGATLTIEGFDALAYHWGIVEERAAAFG-THADRKNWTL
MAV_2779|M.avium_104 LAGKHGIGLLSIGATLTVEGFNALSYHWGIVEERAAAFG-TQVDRTNWSL
Rv3618|M.tuberculosis_H37Rv LAGALGTSLLSLSMSVP-GGYAALETAWGVVREQAAKAGRGEPDRADWRV
Mflv_4544|M.gilvum_PYR-GCK VGGRSRRSLR-------------------------RAVG-----------
Mvan_3368|M.vanbaalenii_PYR-1 VGGRTARSLR-------------------------RAVG-----------
Mb3550c|M.bovis_AF2122/97 LGAEGPKNVALAAEICDGWLPIFYSPRMAGMYNEWLDEG-----------
MLBr_00348|M.leprae_Br4923 LGAEGPKNVALAAEICDGWLPIFFSPRMADMYNEWLDEG-----------
MAB_4628c|M.abscessus_ATCC_199 LAAKWGDPIVTANALQPKENYRVLIDRYRELYAHHGHDP-----------
TH_3375|M.thermoresistible__bu LGNGWLAPELRHWRGLEKRVAALGLDSRTDPFHVAVTVN-----------
MSMEG_3583|M.smegmatis_MC2_155 AGTQGLNYLTSNVVSTEGTISRDFGTIQAEQIDAFLAHH-----------
.
MMAR_2824|M.marinum_M VGPFHIAETDTQARADVKFGIEPWFRYFQKVAAFPQM-TMPGEQ-LDEMI
MUL_2949|M.ulcerans_Agy99 VGPFHIAETDAQARADVKFGIEPWFRYFQKVAAFPQM-TMPGEQ-LDEMI
MAV_2779|M.avium_104 VGLFHLAETEKQAREEVKFGIEPWFRYFQKVAAFPQM-TMPGDQ-LDEMI
Rv3618|M.tuberculosis_H37Rv LSIMHLSDSRDQAIDDCTYGLPDFSRYFGAAGFVPLANTVEGTQSSREFV
Mflv_4544|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3368|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3550c|M.bovis_AF2122/97 ----FARPGARRSREDFEICATAQVVITDDRAAAFAG--------IKPFL
MLBr_00348|M.leprae_Br4923 ----FARTGARRSREDFEICASAQIVVTEDRAAAFAG--------IKPFL
MAB_4628c|M.abscessus_ATCC_199 ------------------------AQLYVGAGSGGLY--------LADTT
TH_3375|M.thermoresistible__bu ----------------------AFVAARDAWETVRPG-------------
MSMEG_3583|M.smegmatis_MC2_155 --------------------------PNPATARVSQG-------------
MMAR_2824|M.marinum_M DIINENGAGVIGTPQRARAQVQRLWDQSGGFGCMLQMGHEWANPAATRRS
MUL_2949|M.ulcerans_Agy99 DIINENGAGVIGTPERARAQVQRLWDQSGGFGCMLQMGHEWANPAATRRS
MAV_2779|M.avium_104 DVINENGAGVIGTPERAREQVQRCWDQSGGFGCMLQMGHEWANPAATKRS
Rv3618|M.tuberculosis_H37Rv EQYAAKGNCCIGTPDDAIAHIEDLLHRSGGFGTLLLLGHDWAPPPATFHS
Mflv_4544|M.gilvum_PYR-GCK ---LADGWMPFGLRTMQIADMLATVDIPDGFDIVLPAG-----PLDPREP
Mvan_3368|M.vanbaalenii_PYR-1 ---LADGWMPFGLTPARIAEMLAAVDIPDDFDIVLAVG-----PLDPRAR
Mb3550c|M.bovis_AF2122/97 ALYMGGMGAEETNFHADVYRRMGYTQVVDEVTKLFRSGRK--DEAAEIIP
MLBr_00348|M.leprae_Br4923 ALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQK--DKAAEIIP
MAB_4628c|M.abscessus_ATCC_199 EQAIAQYRPIYEARLAQMAKLKAHPKAVGKFPSFESIEDAADRGPVLAGS
TH_3375|M.thermoresistible__bu VAHVAGQYRSWLVESGDLPALEGKEFEYEADETGKPPQFVAGTPEQCVAQ
MSMEG_3583|M.smegmatis_MC2_155 ----LVVIPTDSATSAQVHKYRAYATARLERTRTTHGPRGMMFAPDLVGT
MMAR_2824|M.marinum_M AELFAAEVMPHFQGQAQPTLDAAVRAGEVREGLAQTQLQAIDHMTKKYQQ
MUL_2949|M.ulcerans_Agy99 AELFAAEVMPHFQGQAQPTLDAAVRAGEVREGLAQTQLQAIDHMTKKYQQ
MAV_2779|M.avium_104 AELFAAEVMPHFQGQAQPTLDAAARAGQARDSLAQSQLDAVAHMTKKYQG
Rv3618|M.tuberculosis_H37Rv YELFARAVIPYFKGQLAAPRASHEWARGKRDQLIGRAGEAVVKAITEHVA
Mflv_4544|M.gilvum_PYR-GCK SGCLTRLRALRDVGATAVTCSVAADSTDHYCAQLASLRGIVDEL------
Mvan_3368|M.vanbaalenii_PYR-1 DECLNRLRALRDVGATAVTCSLSASSAEHYCDQLASLRDLVDEL------
Mb3550c|M.bovis_AF2122/97 DELVDDAVIVGDIDHVRKQMAVWEAAGVTMMVVTAGSAEQVRDLAALV--
MLBr_00348|M.leprae_Br4923 NELVDSTMIVGDVDYVCKQIAAWSAAGVTMMMVSASSVEQVRDLAGLF--
MAB_4628c|M.abscessus_ATCC_199 PERVAEKILDWHEAFGHEFQSISLSPEADFEEQKDTLRRFAEEVVPLVRA
TH_3375|M.thermoresistible__bu LRPWWRILARLPEHVQPHLILGMTFPGVSREATFESVRLLAREVVPALNA
MSMEG_3583|M.smegmatis_MC2_155 TDELAEMLYEHPGFQRAREVAFALPFTFDEEDYVQIVTDMAEKLGPKLGW
.
MMAR_2824|M.marinum_M ELDSK----------------
MUL_2949|M.ulcerans_Agy99 ELDGK----------------
MAV_2779|M.avium_104 EVESK----------------
Rv3618|M.tuberculosis_H37Rv EQGEAGS--------------
Mflv_4544|M.gilvum_PYR-GCK ---------------------
Mvan_3368|M.vanbaalenii_PYR-1 ---------------------
Mb3550c|M.bovis_AF2122/97 ---------------------
MLBr_00348|M.leprae_Br4923 ---------------------
MAB_4628c|M.abscessus_ATCC_199 EVKSTLWGPLDTRRAKGFTAA
TH_3375|M.thermoresistible__bu EE-------------------
MSMEG_3583|M.smegmatis_MC2_155 TAAEA----------------