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GKLRFGYFIAPFHRAGTNPTLALQRDLEFIEHLDALGFDEVWLGEHHSAGSEIISSPEIFIAAAAERAKR IRFGTGVISLSYHNPLWVADRLMLLDHLTHGRIIGGVGPGSLPTDSSMIGLTPTDTRELLETNLDIVVRL LAGETVSAKTATHQLFDAKLQLGPYSDGGIPLAVAAVASPTGARLAGKHGIGLLSIGATLTVEGFNALSY HWGIVEERAAAFGTQVDRTNWSLVGLFHLAETEKQAREEVKFGIEPWFRYFQKVAAFPQMTMPGDQLDEM IDVINENGAGVIGTPERAREQVQRCWDQSGGFGCMLQMGHEWANPAATKRSAELFAAEVMPHFQGQAQPT LDAAARAGQARDSLAQSQLDAVAHMTKKYQGEVESK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2779 | - | - | 100% (387) | limonene 1,2-monooxygenase |
| M. avium 104 | MAV_0538 | - | 6e-80 | 41.19% (386) | limonene 1,2-monooxygenase |
| M. avium 104 | MAV_0881 | - | 1e-21 | 26.56% (369) | hypothetical protein MAV_0881 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1971 | - | 4e-32 | 27.87% (366) | monooxygenase |
| M. gilvum PYR-GCK | Mflv_4429 | - | 3e-95 | 47.53% (385) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3618 | - | 2e-80 | 41.84% (392) | monooxygenase |
| M. leprae Br4923 | MLBr_00348 | - | 2e-05 | 34.57% (81) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0527c | - | 1e-87 | 46.19% (381) | monooxygenase |
| M. marinum M | MMAR_2824 | - | 0.0 | 87.08% (387) | monooxygenase |
| M. smegmatis MC2 155 | MSMEG_6107 | - | 1e-87 | 43.94% (396) | limonene 1,2-monooxygenase |
| M. thermoresistible (build 8) | TH_0993 | - | 3e-84 | 42.31% (390) | POSSIBLE MONOOXYGENASE |
| M. ulcerans Agy99 | MUL_2949 | - | 0.0 | 87.08% (387) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_1925 | - | 7e-94 | 47.53% (385) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2824|M.marinum_M --MANLRFGYFIAPFHRAGTNPTLALQRDLEFVEHLDALGFDEAWIGEHH
MUL_2949|M.ulcerans_Agy99 --MAKLRFGYFIAPFHRAGTNPTLALQRDLEFVEHLDALGFDEAWIGEHH
MAV_2779|M.avium_104 --MGKLRFGYFIAPFHRAGTNPTLALQRDLEFIEHLDALGFDEVWLGEHH
MSMEG_6107|M.smegmatis_MC2_155 --MRPLNFGVFITPFHPAGQSPTTALQYDMDRVEALDRLGYDEAWFGEHH
TH_0993|M.thermoresistible__bu -VARPLNFGVFITPFHPVGQSPTLALEYDLERTVALDRLGYDEVWFGEHH
Rv3618|M.tuberculosis_H37Rv -MKAPLRFGVFITPFHPTGQSPTVALQYDMERVVALDRLGYDEAWFGEHH
MAB_0527c|M.abscessus_ATCC_199 MSAPPLRFGAFITPFHPVGQNPTTALEYDLDRVVALDRLGYHEAWFGEHH
Mflv_4429|M.gilvum_PYR-GCK -----MRFGNFMAPFHPVGQNPTLALERDLDLIVAMDRLGFHEAWVGEHH
Mvan_1925|M.vanbaalenii_PYR-1 -----MRFGNFMAPFHPVGQNPTLALERDLDLIAAMDRLGFHEAWVGEHH
Mb1971|M.bovis_AF2122/97 -----MEIGIFLMPAHPPERTLYDATRWDLDVIELADQLGYVEAWVGEHF
MLBr_00348|M.leprae_Br4923 ----MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAW
:. . : . : : *: .: **
MMAR_2824|M.marinum_M SAGSEIISSPEVFIAAAAERTKRIRLGTGVISLAYHNPLWVADRLMLLDH
MUL_2949|M.ulcerans_Agy99 SAGSEIISSPEVFIAAAAERTKRIRLGTGVISLAYHNPLWVADRLMLLDH
MAV_2779|M.avium_104 SAGSEIISSPEIFIAAAAERAKRIRFGTGVISLSYHNPLWVADRLMLLDH
MSMEG_6107|M.smegmatis_MC2_155 SGGYELIACPEVFIAAAAERTRHIRLGTGVVSLPYHHPLMVADRWVLLDH
TH_0993|M.thermoresistible__bu SGGYELIASPEVFIAAAAERTRHVRLGTGVVSLPYHHPLMVADRWVLLDH
Rv3618|M.tuberculosis_H37Rv SGGYELIACPEVFIAAAAERTTHIRLGTGVVSLPYHHPLMVADRWVLLDH
MAB_0527c|M.abscessus_ATCC_199 SGGYELISCPEVFIATAAERTKHIKLGTGVVSLPYHHPLMVVDRWILLDH
Mflv_4429|M.gilvum_PYR-GCK SAGFEIIASPEVFLGVAAERTKHIRLGTGVSSLPYHHPLMLADRMVLLDH
Mvan_1925|M.vanbaalenii_PYR-1 SAGFEIIASPEVFIGIAAERTKHIKLGTGVSSLPYHHPLLLADRMVLLDH
Mb1971|M.bovis_AF2122/97 TVPWEPICAPDLLLAQALLRTQQIKLAPGAHLLPYHHPVELAHRVAYFDH
MLBr_00348|M.leprae_Br4923 GS------DAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDH
. :. : ::::.... *. : * . :**
MMAR_2824|M.marinum_M LTHGRVIGGMGPGSLPTDSAMIGLTPT--DTRELLETNLDIVVRLLAG--
MUL_2949|M.ulcerans_Agy99 LTHGRVIGGMGPGSLATDSAMIGLTPT--DTRELLETNLDIVVRLLAG--
MAV_2779|M.avium_104 LTHGRIIGGVGPGSLPTDSSMIGLTPT--DTRELLETNLDIVVRLLAG--
MSMEG_6107|M.smegmatis_MC2_155 LTRGRVMFGTGPGALPSDAYMMGIDPV--DQRPMMQESLEAILALFRAEP
TH_0993|M.thermoresistible__bu ITRGRVMFGAGPGALPSDAYMMGIDPV--NQRPMMQEALEAILALLRAAP
Rv3618|M.tuberculosis_H37Rv LTRGRVMFGTGPGALPSDAYMMGIDPV--EQRRMMQESLEAILALFRAAP
MAB_0527c|M.abscessus_ATCC_199 ITRGRVIFGTGPGALPTDAYMMGIDPV--DQRRMQEESLEAILALLRATP
Mflv_4429|M.gilvum_PYR-GCK LTRGRVMLGCGPGQLTSDAHMLGIPAD--EQRPRMEQCLDAIVRLLRG--
Mvan_1925|M.vanbaalenii_PYR-1 LTRGRVMLGCGPGQLTSDAHMLGIPAD--AQRPRMEQSLDAIVRLLRG--
Mb1971|M.bovis_AF2122/97 LAQGRFMLGVGASGIPGDWALYDVDGKNGEHREMTREALEIMLRIWTE--
MLBr_00348|M.leprae_Br4923 LSGGRHILGLGVSGPQVVEGWYGQPFP--KPLSRTREYIDIVRQVWAR--
:: ** : * * . . . :: : :
MMAR_2824|M.marinum_M -QTVTAKTATHQLF--------DARLQLAPFSEGG-IPLAVAAVAS-PTG
MUL_2949|M.ulcerans_Agy99 -QTVTAKTATHQLF--------DARLQLAPFSEGG-IPLAVAAVAS-PTG
MAV_2779|M.avium_104 -ETVSAKTATHQLF--------DAKLQLGPYSDGG-IPLAVAAVAS-PTG
MSMEG_6107|M.smegmatis_MC2_155 GERIDRKTDWFTLR--------DAALHIRPYTWPY-PEISTAAMIS-PSG
TH_0993|M.thermoresistible__bu DERISRETDWFTLR--------DAQLHIRPYTWPY-PEISTAAMIS-PSG
Rv3618|M.tuberculosis_H37Rv DERIDRHSDWFTLR--------EAQLHIRPYTWPY-PEIATAAMIS-PSG
MAB_0527c|M.abscessus_ATCC_199 QERINRETSWFTLR--------DAQLQLRPYTHPY-PEILTAAMFS-PSG
Mflv_4429|M.gilvum_PYR-GCK -ETVTMHTDGFTLQ--------DARLQLKPYSEPC-FDIAVAASFS-PTG
Mvan_1925|M.vanbaalenii_PYR-1 -ETVTMHTDGFTLQ--------DARLQLKPYSDPC-FDIAVAASFS-PTG
Mb1971|M.bovis_AF2122/97 DEPWEHRGKYWNANGIAPMFEGLMRRHIKPYQKPH-PPIGVTGFSAGSET
MLBr_00348|M.leprae_Br4923 EAPVVSDGQHYPLPLTGAG-ATGLGKALKPITHPLRADIPIMLGAEGPKN
: * : .
MMAR_2824|M.marinum_M ARLAGRHGIGLLSIGATLTIEGFDALAYHWGIVEERAAAFGT-HADRKNW
MUL_2949|M.ulcerans_Agy99 ARLAGRHGIGLLSIGATLTIEGFDALAYHWGIVEERAAAFGT-HADRKNW
MAV_2779|M.avium_104 ARLAGKHGIGLLSIGATLTVEGFNALSYHWGIVEERAAAFGT-QVDRTNW
MSMEG_6107|M.smegmatis_MC2_155 PRLAGKLGTSLLSLSMSVP-GGYAAVETTWNVVRDEAAAAGRPEPDRENW
TH_0993|M.thermoresistible__bu PRLAGSLGTSLLSLSMSVP-GGYAAVENTWDVVVQQAAKAGRPEPDRANW
Rv3618|M.tuberculosis_H37Rv PRLAGALGTSLLSLSMSVP-GGYAALETAWGVVREQAAKAGRGEPDRADW
MAB_0527c|M.abscessus_ATCC_199 PRLAGKLGAGLLSLSASIP-GGFAALENAWEVVREQAEIHGHPEPDRSSW
Mflv_4429|M.gilvum_PYR-GCK PRGAGRHGIGMLSIAATAR-QGMDLLAQHWNTWDEVAREHGH-QADRSKW
Mvan_1925|M.vanbaalenii_PYR-1 PRGAGRHGIGMLSIAATAK-QGMDLLAQHWNTWEEVAREHGH-VADRAKW
Mb1971|M.bovis_AF2122/97 LKLAGERGYIPMSLDLNTE-----YVATHWDAVEEGALRSGR-TPDRRDW
MLBr_00348|M.leprae_Br4923 VALAAEICDGWLPIFFSPR------MADMYNEWLDEGFARTGARRSREDF
*. :.: . : : : . .* .:
MMAR_2824|M.marinum_M TLVGPFHIAETDTQARADVKFG--IEPWFRYFQKVAAFP-QMTMPGEQ--
MUL_2949|M.ulcerans_Agy99 TLVGPFHIAETDAQARADVKFG--IEPWFRYFQKVAAFP-QMTMPGEQ--
MAV_2779|M.avium_104 SLVGLFHLAETEKQAREEVKFG--IEPWFRYFQKVAAFP-QMTMPGDQ--
MSMEG_6107|M.smegmatis_MC2_155 RVLGIVHLADTREQAIEDCTYG--LQDFANYFGAAGFVPLSNQAEGGG--
TH_0993|M.thermoresistible__bu RVLGIVHLADTREQALQDCTYG--LQDFANYFGAAGFVPLANEVAGGQ--
Rv3618|M.tuberculosis_H37Rv RVLSIMHLSDSRDQAIDDCTYG--LPDFSRYFGAAGFVPLANTVEGTQ--
MAB_0527c|M.abscessus_ATCC_199 RVLGIMHLAETRDQAIADCTYG--LPDYAHYFGAVGVLPLANSADGADGA
Mflv_4429|M.gilvum_PYR-GCK RLVGPMHLAETREQAERDVEYG--IAEFSRYF---THILPSGPVQGDT--
Mvan_1925|M.vanbaalenii_PYR-1 RLVGPMHLAETREQAERDVEYG--IAQFSQYF---SHILPAGPVQGDT--
Mb1971|M.bovis_AF2122/97 RLVREVLVAETDEQAFRYAVDGTMGRAMREYVLPTFRMFGMTKFYKHNPS
MLBr_00348|M.leprae_Br4923 EICASAQIVVTEDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMG--
: : : :* .
MMAR_2824|M.marinum_M --LDEMIDIINENGAGVIGTPQRARAQVQRLWDQS-GGFGCMLQMGHEWA
MUL_2949|M.ulcerans_Agy99 --LDEMIDIINENGAGVIGTPERARAQVQRLWDQS-GGFGCMLQMGHEWA
MAV_2779|M.avium_104 --LDEMIDVINENGAGVIGTPERAREQVQRCWDQS-GGFGCMLQMGHEWA
MSMEG_6107|M.smegmatis_MC2_155 -TPYEFVENYASKGNCCIGTPDDAIVYIQDLLDRS-GGFGTFLLLGHDWA
TH_0993|M.thermoresistible__bu -SPREFVEAYAEKGNCCIGTPGDAIVYLSDLLERS-GGFGTFLMLGHDWA
Rv3618|M.tuberculosis_H37Rv -SSREFVEQYAAKGNCCIGTPDDAIAHIEDLLHRS-GGFGTLLLLGHDWA
MAB_0527c|M.abscessus_ATCC_199 IDPHEFVKAYADEGNCCIGTPEDAIEYIQGLLDTS-GGFGTFLMLGHDWA
Mflv_4429|M.gilvum_PYR-GCK --PEEIIANNRQSGFAVIGTPDDAIAKISELVEASDGGFGAFLLFDHDWA
Mvan_1925|M.vanbaalenii_PYR-1 --PAEIIANNHASGFAVIGTPQDAIAKIEELVEASNGGFGTFLLFDHDWA
Mb1971|M.bovis_AF2122/97 VPDDEVTPEYLAENTFVVGSVQTVVDKLEATYDQV-GGFGHLLILGFDYS
MLBr_00348|M.leprae_Br4923 --YAEVVDEVT--ALFRSNQKDKAAEIIPNELVDS-----TMIVGDVDYV
*. . . : :: . ::
MMAR_2824|M.marinum_M N-PAATRRSAELFAAEVMPHFQGQAQPTLDAAVRAGEVREGLAQTQLQAI
MUL_2949|M.ulcerans_Agy99 N-PAATRRSAELFAAEVMPHFQGQAQPTLDAAVRAGEVREGLAQTQLQAI
MAV_2779|M.avium_104 N-PAATKRSAELFAAEVMPHFQGQAQPTLDAAARAGQARDSLAQSQLDAV
MSMEG_6107|M.smegmatis_MC2_155 P-PAATFHSYELFAREVIPHFKGQLTAARASHDWAKGMRDQLLGRAGQAI
TH_0993|M.thermoresistible__bu S-PQATYHSYELFAREVIPHFKGQLTAPRASHDWAKQMRGQLLGRAGEAI
Rv3618|M.tuberculosis_H37Rv P-PPATFHSYELFARAVIPYFKGQLAAPRASHEWARGKRDQLIGRAGEAV
MAB_0527c|M.abscessus_ATCC_199 A-PEATFKSYELFARKVIPHFTGQLTAAQASHDWAQAKRGELLGRAGDAV
Mflv_4429|M.gilvum_PYR-GCK P-PAAKLRSYELFAQYVIPHFTGQLSAPIASRDWVTESGRVFVDQATHAI
Mvan_1925|M.vanbaalenii_PYR-1 P-PAAKLRSYELFAEYVIPHFTGQLSAPIASRDWVTESGRTFVDQAAHAI
Mb1971|M.bovis_AF2122/97 DNPGPWKESLRLLAHEVMPRLNARLATKPATAVV----------------
MLBr_00348|M.leprae_Br4923 CKQIAAWSAAGVTMMMVSASSVEQVRDLAGLF------------------
. : : * . :
MMAR_2824|M.marinum_M DHMTKKYQQELDSK------
MUL_2949|M.ulcerans_Agy99 DHMTKKYQQELDGK------
MAV_2779|M.avium_104 AHMTKKYQGEVESK------
MSMEG_6107|M.smegmatis_MC2_155 VNAITEHTQAHPAENEN---
TH_0993|M.thermoresistible__bu VKAIGEHTSEQEQR------
Rv3618|M.tuberculosis_H37Rv VKAITEHVAEQGEAGS----
MAB_0527c|M.abscessus_ATCC_199 AKAIGEHVAQKASH------
Mflv_4429|M.gilvum_PYR-GCK GRAIESHAAEQQAKQSRTSD
Mvan_1925|M.vanbaalenii_PYR-1 GKAIEDHAAEQQAKSPTPS-
Mb1971|M.bovis_AF2122/97 --------------------
MLBr_00348|M.leprae_Br4923 --------------------