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RFQLLDIVFHLPNPATRALAPAAERLNRVIETAVLAENLGFDSFAVGERHAGDVLSSAPTVLLGAVAAAT DRILLSTGVTVLSLLDPVRAAEDFATIDQLSRGRLEIVIGKGNEDRQYPLMGLDIAKQYEYLQENYELLR RLLREEHVDWVGVHRHPLADATTLPRPYDGPFRIWHGSATSTFAVELAAKWGDPIVTANALQPKENYRVL IDRYRELYAHHGHDPAQLYVGAGSGGLYLADTTEQAIAQYRPIYEARLAQMAKLKAHPKAVGKFPSFESI EDAADRGPVLAGSPERVAEKILDWHEAFGHEFQSISLSPEADFEEQKDTLRRFAEEVVPLVRAEVKSTLW GPLDTRRAKGFTAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4628c | - | - | 100% (365) | luciferase-like monooxygenase |
| M. abscessus ATCC 19977 | MAB_3232c | - | 7e-37 | 31.78% (321) | putative luciferase-like oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0527c | - | 1e-16 | 27.25% (334) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2185c | - | 1e-08 | 27.43% (175) | hypothetical protein Mb2185c |
| M. gilvum PYR-GCK | Mflv_4429 | - | 3e-15 | 27.47% (324) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3618 | - | 3e-14 | 26.30% (289) | monooxygenase |
| M. leprae Br4923 | MLBr_00269 | - | 3e-05 | 29.85% (134) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. marinum M | MMAR_1055 | - | 3e-18 | 27.39% (314) | flavin-dependent oxidoreductase |
| M. avium 104 | MAV_2779 | - | 8e-18 | 26.32% (342) | limonene 1,2-monooxygenase |
| M. smegmatis MC2 155 | MSMEG_4092 | - | 2e-20 | 32.56% (215) | alkanal monooxygenase |
| M. thermoresistible (build 8) | TH_3375 | - | 3e-24 | 30.52% (344) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0814 | - | 3e-16 | 26.75% (314) | flavin-dependent oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_1925 | - | 9e-16 | 27.61% (326) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4429|M.gilvum_PYR-GCK ------MRFGNFMAPFHPVGQNP----------TLALERDLDLIVAMDRL
Mvan_1925|M.vanbaalenii_PYR-1 ------MRFGNFMAPFHPVGQNP----------TLALERDLDLIAAMDRL
Rv3618|M.tuberculosis_H37Rv --MKAPLRFGVFITPFHPTGQSP----------TVALQYDMERVVALDRL
MAV_2779|M.avium_104 ---MGKLRFGYFIAPFHRAGTNP----------TLALQRDLEFIEHLDAL
MMAR_1055|M.marinum_M ------MRFSIAIPQLDTDG--------------FDAAGLRAYLARAEEL
MUL_0814|M.ulcerans_Agy99 ------MRFSIAIPQLDTDG--------------FDAAGLRAYLARAEEL
MAB_4628c|M.abscessus_ATCC_199 ------MRFQLLDIVFHLPNPATRALAP----AAERLNRVIETAVLAENL
TH_3375|M.thermoresistible__bu ------VGLGALTAQTRSGTAAES---------TEALTMLLDTCVLAEDE
MSMEG_4092|M.smegmatis_MC2_155 MTRVATNRIGAGVEDGRPFRLGFLLHLDRDIPPAQAYREAVELFVAAEQL
Mb2185c|M.bovis_AF2122/97 ----MLVSLMQFVTDLTPPPQLVAVWAE-----ERGFAGLYVPEKTHVPI
MLBr_00269|M.leprae_Br4923 ---MAELRLGYKASAEQFAP-----------------RELVELGVAAEAH
:
Mflv_4429|M.gilvum_PYR-GCK GFHEAWVGEHHSAG---FEIIASPEVFLGVAAERTKHIRLGTGVSSLPY-
Mvan_1925|M.vanbaalenii_PYR-1 GFHEAWVGEHHSAG---FEIIASPEVFIGIAAERTKHIKLGTGVSSLPY-
Rv3618|M.tuberculosis_H37Rv GYDEAWFGEHHSGG---YELIACPEVFIAAAAERTTHIRLGTGVVSLPY-
MAV_2779|M.avium_104 GFDEVWLGEHHSAG---SEIISSPEIFIAAAAERAKRIRFGTGVISLSY-
MMAR_1055|M.marinum_M GFEGGWVLEQIIGS---SPLLA-PLELLAYCAACTNRLRLGVAVLVTSL-
MUL_0814|M.ulcerans_Agy99 GFEGGWGLEQIIGS---SPLLA-PLQLLAYCAACTNRLRLGVAVLVTSL-
MAB_4628c|M.abscessus_ATCC_199 GFDSFAVGERHAG----DVLSSAPTVLLGAVAAATDRILLSTGVTVLSL-
TH_3375|M.thermoresistible__bu GLDSAWVAEHHFAA---DGFLSSPMTVLAALSQRTSRIRLSTNVMIGPL-
MSMEG_4092|M.smegmatis_MC2_155 GYDSGWVIHRHFRQG--NEHVSAPLVLLAAIAQHTSRIRLGTGVLVLAL-
Mb2185c|M.bovis_AF2122/97 SRSTPWPGGELPDW---YRRCYDPVVALAAAAAVTTRLRVGTGACLVAV-
MLBr_00269|M.leprae_Br4923 GMDSATVSDHFQPWRHQGGHASFSLSWMTAVGERTNRILLGTSVLTPTFR
. . . : . : :: ... . .
Mflv_4429|M.gilvum_PYR-GCK HHPLMLADRMVLLDHLTRGRVMLGCGPGQLT----SDAHMLGIPADEQRP
Mvan_1925|M.vanbaalenii_PYR-1 HHPLLLADRMVLLDHLTRGRVMLGCGPGQLT----SDAHMLGIPADAQRP
Rv3618|M.tuberculosis_H37Rv HHPLMVADRWVLLDHLTRGRVMFGTGPGALP----SDAYMMGIDPVEQRR
MAV_2779|M.avium_104 HNPLWVADRLMLLDHLTHGRIIGGVGPGSLP----TDSSMIGLTPTDTRE
MMAR_1055|M.marinum_M HDPLQLASSVTAVDRLSNGRLDLGVAAGGGS----RKFAAFGVDRATHVS
MUL_0814|M.ulcerans_Agy99 HDPLQLASSVTAVDRLSNGRLDLGVAAGGGS----RKFAAFGVDRATHVS
MAB_4628c|M.abscessus_ATCC_199 LDPVRAAEDFATIDQLSRGRLEIVIGKGNED----RQYPLMGLDIAKQYE
TH_3375|M.thermoresistible__bu YDPIRLAEDAAVVDQLSRGRLMLGLGLGYRD----VEFAGLGRRRQERGR
MSMEG_4092|M.smegmatis_MC2_155 EDPLKVAEDAATLDEISGGRLELGVGSGPFP----SAWEAFGRDLNDRHR
Mb2185c|M.bovis_AF2122/97 HDPILLAKQIASLCAMSGERFVLGVGFGWNV----EELADHGVPFADRIA
MLBr_00269|M.leprae_Br4923 YNPAVIGQAFATMGCLYPNRVFLGVGTGEALNEVATGYQGAWPEFKERFA
.* .. : : *. . *
Mflv_4429|M.gilvum_PYR-GCK RMEQCLDAIVRLLRG---ETVTMHTDGFTLQDARLQLKPYSEPCFDIAVA
Mvan_1925|M.vanbaalenii_PYR-1 RMEQSLDAIVRLLRG---ETVTMHTDGFTLQDARLQLKPYSDPCFDIAVA
Rv3618|M.tuberculosis_H37Rv MMQESLEAILALFRAAPDERIDRHSDWFTLREAQLHIRPYTWPYPEIATA
MAV_2779|M.avium_104 LLETNLDIVVRLLAG---ETVSAKTATHQLFDAKLQLGPYSDGGIPLAVA
MMAR_1055|M.marinum_M YFTEGLQLMKAAWSD--EPRVRFHGRFRDVDDLPIQPKPVQRPHPPIWFG
MUL_0814|M.ulcerans_Agy99 YFTEGLQLMKAAWSD--EPRVRFHGRFRDVDDLPIQPKRVQRPHPPIWFG
MAB_4628c|M.abscessus_ATCC_199 YLQENYELLRRLLREEHVDWVGVHR--HPLADATTLPRPYDGP-FRIWHG
TH_3375|M.thermoresistible__bu RLDDLINVLRQAWSG----KPVEHHGLGTYKTPPVTPLPFQQDGPPVLVG
MSMEG_4092|M.smegmatis_MC2_155 IFNDVVDRLHDVLDG---HVLNSVGETLHPPGAGVRRRLWQAITSDAVHS
Mb2185c|M.bovis_AF2122/97 VTVDKLAAMRALWAA-----EPVHYEGTHASVPPSWAWPKPAVAPPVLFG
MLBr_00269|M.leprae_Br4923 RLRESVRLMRELWRG---DRVDFDGDYYQLKGASIYDVPEGGVPIYIAAG
: .
Mflv_4429|M.gilvum_PYR-GCK ASFSPTGPRGAGRHGIGMLSIAATAR-QGMDLLAQHWNTWDEVAREHG-H
Mvan_1925|M.vanbaalenii_PYR-1 ASFSPTGPRGAGRHGIGMLSIAATAK-QGMDLLAQHWNTWEEVAREHG-H
Rv3618|M.tuberculosis_H37Rv AMISPSGPRLAGALGTSLLSLSMSVP-GGYAALETAWGVVREQAAKAGRG
MAV_2779|M.avium_104 AVASPTGARLAGKHGIGLLSIGATLTVEGFNALSYHWGIVEERAAAFG-T
MMAR_1055|M.marinum_M GRAPKALAR-AVRHGDAFLGAGSSTT----ADFATAVTTLRHELAEQG-R
MUL_0814|M.ulcerans_Agy99 GRAPKALAR-AVRHGDAFLGAGSSTT----ADFATAVTTLRHELAEQG-R
MAB_4628c|M.abscessus_ATCC_199 SATSTFAVELAAKWGDPIVTANALQP---KENYRVLIDRYRELYAHHGHD
TH_3375|M.thermoresistible__bu -AFAEAGLRRAVRLGNGWLAP-----------ELRHWRGLEKRVAALG-L
MSMEG_4092|M.smegmatis_MC2_155 GPAAVRAATAGDGLQLSRATAWQGGS---VEDAQIRQSEWIAAYRDAWAD
Mb2185c|M.bovis_AF2122/97 CRPSARAFEVIARHGDGWQPIEG------YGELLGALPMLHAAFERAG--
MLBr_00269|M.leprae_Br4923 ---GPEVAKYAGRAGEGFVCTSGKGE---ELYTEKLIPAVLEGAAVAG-R
Mflv_4429|M.gilvum_PYR-GCK QADRSKWRLVGPMHLAETREQAERDVEYGIAEFSRYF---THILPSGPVQ
Mvan_1925|M.vanbaalenii_PYR-1 VADRAKWRLVGPMHLAETREQAERDVEYGIAQFSQYF---SHILPAGPVQ
Rv3618|M.tuberculosis_H37Rv EPDRADWRVLSIMHLSDSRDQAIDDCTYGLPDFSRYFGAAGFVPLANTVE
MAV_2779|M.avium_104 QVDRTNWSLVGLFHLAETEKQAREEVKFGIEPWFRYFQK-VAAFPQMTMP
MMAR_1055|M.marinum_M DPAGFTIGKRVYLMVDDDPERARERVLAGLRSIYGKMG------------
MUL_0814|M.ulcerans_Agy99 DPAGFTIGKRVYLMVDDDPERARERVLAGLRSIYGKMG------------
MAB_4628c|M.abscessus_ATCC_199 PAQLYVGAGSGGLYLADTTEQAIAQYRPIYEARLAQMAK---LKAHPKAV
TH_3375|M.thermoresistible__bu DSRTDPFHVAVTVNAFVAARDAWETVRPGVAHVAGQYRSWLVESGDLPAL
MSMEG_4092|M.smegmatis_MC2_155 PASPPRVQVSRAVYPHGDRAEALRLVTPGVRRWQSWSTH-----------
Mb2185c|M.bovis_AF2122/97 ---RDPATAQVCVYSSAGDPATLHEYRR----------------------
MLBr_00269|M.leprae_Br4923 DADDIDKMIEIKMSYDPDPEQALSNIRFWAPLSLAAEQK---HSIDDPIE
. :
Mflv_4429|M.gilvum_PYR-GCK G-DTPEEIIANNRQSGFAVIGTPDDAIAKISELVEASD-----GGFGAFL
Mvan_1925|M.vanbaalenii_PYR-1 G-DTPAEIIANNHASGFAVIGTPQDAIAKIEELVEASN-----GGFGTFL
Rv3618|M.tuberculosis_H37Rv GTQSSREFVEQYAAKGNCCIGTPDDAIAHIEDLLHRS------GGFGTLL
MAV_2779|M.avium_104 G-DQLDEMIDVINENGAGVIGTPERAREQVQRCWDQS------GGFGCML
MMAR_1055|M.marinum_M ------------GLDAVAVAGTPDDVTRGLAEVIAAG---------AQTL
MUL_0814|M.ulcerans_Agy99 ------------GLDAVAVAGTPDDVTRGLAEVIAAG---------AQTL
MAB_4628c|M.abscessus_ATCC_199 GKFPSFESIEDAADRGPVLAGSPERVAEKILDWHEAFG-----HEFQSIS
TH_3375|M.thermoresistible__bu EGKEFEYEADETGKPPQFVAGTPEQCVAQLRPWWRILARLPEHVQPHLIL
MSMEG_4092|M.smegmatis_MC2_155 GDPRQTETVDEYLTADRALIGPGAELADELASDPALR------HASDLLL
Mb2185c|M.bovis_AF2122/97 ------------AGVAEVALALPSAGRDQVLAALDRS-------------
MLBr_00269|M.leprae_Br4923 MEKVADALPIEQVAKRWIVVSDPDEAVARVGQYVTWG------------L
. :
Mflv_4429|M.gilvum_PYR-GCK LFDHDWAPPAAKLRSYELFAQYVIPHFTGQLSAPIASRDWVTESGRVFVD
Mvan_1925|M.vanbaalenii_PYR-1 LFDHDWAPPAAKLRSYELFAEYVIPHFTGQLSAPIASRDWVTESGRTFVD
Rv3618|M.tuberculosis_H37Rv LLGHDWAPPPATFHSYELFARAVIPYFKGQLAAPRASHEWARGKRDQLIG
MAV_2779|M.avium_104 QMGHEWANPAATKRSAELFAAEVMPHFQGQAQPTLDAAARAGQARDSLAQ
MMAR_1055|M.marinum_M LLNPVGPDVGQNHEQMERLAAEVIPRLR----------------------
MUL_0814|M.ulcerans_Agy99 LLNPVGPDVGQNHEQTERLAAEVIPRLR----------------------
MAB_4628c|M.abscessus_ATCC_199 LS--PEADFEEQKDTLRRFAEEVVPLVRAEVKSTLWGPLDTRRAKGFTAA
TH_3375|M.thermoresistible__bu GMTFPGVSREATFESVRLLAREVVPALNAEE-------------------
MSMEG_4092|M.smegmatis_MC2_155 SFVPGVPEHGEHLRLLEDTARELVPRLGWYPSTGVS--------------
Mb2185c|M.bovis_AF2122/97 ---------APLVDAFAGDDREVKSHA-----------------------
MLBr_00269|M.leprae_Br4923 NHLVFHAPGHNQRRFLELFEKDLAPRLRRLG-------------------
: .
Mflv_4429|M.gilvum_PYR-GCK QATHAIGRAIESHAAEQQAKQSRTSD
Mvan_1925|M.vanbaalenii_PYR-1 QAAHAIGKAIEDHAAEQQAKSPTPS-
Rv3618|M.tuberculosis_H37Rv RAGEAVVKAITEHVAEQGEAGS----
MAV_2779|M.avium_104 SQLDAVAHMTKKYQGEVESK------
MMAR_1055|M.marinum_M --------------------------
MUL_0814|M.ulcerans_Agy99 --------------------------
MAB_4628c|M.abscessus_ATCC_199 --------------------------
TH_3375|M.thermoresistible__bu --------------------------
MSMEG_4092|M.smegmatis_MC2_155 --------------------------
Mb2185c|M.bovis_AF2122/97 --------------------------
MLBr_00269|M.leprae_Br4923 --------------------------