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SAHQPHTVSSPRHVPIDDRPLTAFHKRLTVFSAGGPFLDGFALTIIGIALISMVPALDMSTVDVGLVGAS ALIGIFVGGLVFGYVTDRVGRKVMYIADLTMLVVVSIASAFATEVWQLVALRFLLGVAIGADYPIASSLL AEFIPSRYRGRLLGALFVVWAGGAAAAAGVGWALSTMGPDAWRWMLASPAVFGVVTLMLRAGTPESPRWL LSRGRTEEAQRVCRKVWGNDADIAMIPAEPAHTPFTALFRGIYLRRVVFVGVFFTAHVIPLFAVYTFGPD ILREMGVGAHGSHHVYVAELVISLLFLVGGVPGLLLVDRIGRKPLLLWTFAVMSAAFIAMAVVPGAPAQI LFALLALYAVTSGACNFIEIIYPNELFPTSVRASATGTVVAISRVGSAVSTFVLPLVLSGTGLGGVMWLL AGVNVVGLLVTLVLGEETRGRALSETSAATRLTEPETRSDPVDA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2966 | - | - | 100% (465) | major facilitator family protein transporter |
| M. smegmatis MC2 155 | MSMEG_4078 | - | 3e-91 | 40.22% (455) | metabolite transport protein YaaU |
| M. smegmatis MC2 155 | MSMEG_3536 | - | 9e-38 | 27.86% (499) | sugar transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3364 | sugI | 2e-30 | 28.12% (441) | sugar-transport integral membrane protein SugI |
| M. gilvum PYR-GCK | Mflv_3055 | - | 4e-28 | 26.91% (457) | sugar transporter |
| M. tuberculosis H37Rv | Rv3331 | sugI | 2e-30 | 28.12% (441) | sugar-transport integral membrane protein SugI |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0692c | - | 1e-32 | 26.97% (456) | sugar transporter |
| M. marinum M | MMAR_2574 | - | 3e-40 | 28.60% (500) | sugar transporter |
| M. avium 104 | MAV_3053 | - | 2e-36 | 27.31% (498) | sugar transport protein |
| M. thermoresistible (build 8) | TH_3722 | - | 5e-16 | 26.24% (404) | PUTATIVE General substrate transporter |
| M. ulcerans Agy99 | MUL_3187 | - | 1e-37 | 28.33% (473) | sugar transporter |
| M. vanbaalenii PYR-1 | Mvan_3472 | - | 2e-31 | 26.49% (453) | sugar transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2574|M.marinum_M ------------------------MSARAQTGTISTHVPARLDRLPWGRF
MUL_3187|M.ulcerans_Agy99 --------------------------------------------------
MAV_3053|M.avium_104 ------------------------MSAGAQTNTITTHVPARLDRLPWSRF
Mb3364|M.bovis_AF2122/97 MTTLWQPHRNDYSPIPGRGVHARRGARRPRPRGGRAERPGTGQLTRSGRR
Rv3331|M.tuberculosis_H37Rv MTTLWQPHRNDYSPIPGRGVHARRGARRPRPRGGRAERPGTGQLTRSGRR
Mflv_3055|M.gilvum_PYR-GCK ------------------------MAGQGGPAGESPELYEKGQDFSSGKT
Mvan_3472|M.vanbaalenii_PYR-1 ------------------------MAGQGGPVGDGPEIFEQGQEFSSGKT
MAB_0692c|M.abscessus_ATCC_199 --------------------------------------MSEEDEFSSGHS
MSMEG_2966|M.smegmatis_MC2_155 -------------------------MSAHQPHTVSSPRHVPIDDRPLTAF
TH_3722|M.thermoresistible__bu -------------------------VSENPSIVSAPPAPDAVVIRKAVTG
MMAR_2574|M.marinum_M HWRVVIGLGGVWVLDGLEVTMVGNVSARLTEHGSGINLTPAQIGVAASFY
MUL_3187|M.ulcerans_Agy99 ----MIGLGGVWVLDGLEVTMVGNVSARLTEHGSGINLTPAQIGVAASFY
MAV_3053|M.avium_104 HWRVVIGLGGVWVLDGLEVTMVGNVSARLMEPGSGIALNPAQIGMAAAIY
Mb3364|M.bovis_AF2122/97 ALLVGLTAASVGVLYGYDLSAIAGALLSLSEE---FELTTREQELLTTTA
Rv3331|M.tuberculosis_H37Rv ALLVGLTAASVGVLYGYDLSAIAGALLSLSEE---FELTTREQELLTTTA
Mflv_3055|M.gilvum_PYR-GCK AIRIASVAALGGLLFGYDSAVINGAVASIQED---FGIGNYALGLAVASA
Mvan_3472|M.vanbaalenii_PYR-1 AVRIASVAALGGLLFGYDSAVINGAVDSIQED---FGIGNAELGFAVASA
MAB_0692c|M.abscessus_ATCC_199 ALRIASVAALGGLLFGYDSAVINGAVQAIQDA---FAIRDAELGFAVASA
MSMEG_2966|M.smegmatis_MC2_155 HKRLTVFSAGGPFLDGFALTIIGIALISMVPA---LDMSTVDVGLVGASA
TH_3722|M.thermoresistible__bu ASIGNAVEWFDFAIYGFLATYIAANFFPAGDD----TAALLNTFAIFAAA
: * : : :
MMAR_2574|M.marinum_M IAGACLGALFFGHLTDRFGRRNLFLLTLAVYLTATVATAFA--------F
MUL_3187|M.ulcerans_Agy99 IAGACLGALFFGHLTDRFGRRNLFLLTLAVYLTATVATAFA--------F
MAV_3053|M.avium_104 IAGACSGALFFGHLTDRFGRRNLFILTLALYLIATVATAFA--------F
Mb3364|M.bovis_AF2122/97 VLGQIAGALGGGILANAIGRKKSVVLIVAGYAVFALLGATS--------V
Rv3331|M.tuberculosis_H37Rv VLGQIAGALGGGILANAIGRKKSVVLIVAGYAVFALLGATS--------V
Mflv_3055|M.gilvum_PYR-GCK LLGAAVGALSAGRIADRIGRIAVMKIAAVLFLLSAFGTAFA--------P
Mvan_3472|M.vanbaalenii_PYR-1 LLGAAAGAMTAGRIADRIGRIAVMKIAAVLFLVSAFGTGFA--------H
MAB_0692c|M.abscessus_ATCC_199 LLGAAVGAMTAGRVADRIGRVAVMKIAAALFLLSAVGAGLA--------P
MSMEG_2966|M.smegmatis_MC2_155 LIGIFVGGLVFGYVTDRVGRKVMYIADLTMLVVVSIASAFA--------T
TH_3722|M.thermoresistible__bu FVVRPLGGFFFGPLGDRIGRQRVLALVILLMSGATLTMGLLPTYESIGVL
. *.: * : : .** :. .
MMAR_2574|M.marinum_M APWYFFIARFFTGSGIGGEYAAINSAIDELIPARVRGRVDLIINGTYWLG
MUL_3187|M.ulcerans_Agy99 APWYFFIARFFTGSGIGGEYAAINSAIDELIPARVRGRVDLIINGTYWLG
MAV_3053|M.avium_104 APWYFFLTRFFTGAGIGGEYAAINSAIDELIPARVRGRVDLVINGTYWLG
Mb3364|M.bovis_AF2122/97 SVPMLVVARLLLGVTIGLSVVVVPVYVAESAPAAVRGSLVTAYQLATLSG
Rv3331|M.tuberculosis_H37Rv SVPMLVVARLLLGVTIGLSVVVVPVYVAESAPAAVRGSLVTAYQLATLSG
Mflv_3055|M.gilvum_PYR-GCK ETITLVIGRIVGGVGVGVASVIAPAYIAETSPPGIRGRLGSLQQLAIVSG
Mvan_3472|M.vanbaalenii_PYR-1 EVWAVVLFRIVGGIGVGVASVIAPAYIAETSPPGIRGRLGSLQQLAIVSG
MAB_0692c|M.abscessus_ATCC_199 NIELLVLFRVIGGVGVGVASLIAPAYIAETSPSRIRGRLGSLQQLAIVTG
MSMEG_2966|M.smegmatis_MC2_155 EVWQLVALRFLLGVAIGADYPIASSLLAEFIPSRYRGRLLGALFVVWAGG
TH_3722|M.thermoresistible__bu APLLLLLLRCLQGFSAGGEYGGGAVYLAEFAPDRRRGLIVTFMAWSGVLG
.. * . * * : * * ** : *
MMAR_2574|M.marinum_M SAAGAAGALVLLDTSN------FAPNMGWRLAFGLGAIFGIFVLLVRRNV
MUL_3187|M.ulcerans_Agy99 SAAGAAGALVLLDTSN------FAPNMGWRLAFGLGAIFGIFVLLVRRNV
MAV_3053|M.avium_104 SAAGAGGALILLDTSN------FAADLGWRLAFGIGAILGIFVLLVRRNV
Mb3364|M.bovis_AF2122/97 IVVGYLVGYLLAGSHG------------WRAMFGLAAAPATLLLPLLWRM
Rv3331|M.tuberculosis_H37Rv IVVGYLVGYLLAGSHG------------WRAMFGLAAAPATLLLPLLWRM
Mflv_3055|M.gilvum_PYR-GCK IFASFAVNYLLQWLAGGPNEPLWLGMDAWRWMFLAMAVPAVVYGGLAFTI
Mvan_3472|M.vanbaalenii_PYR-1 IFASFAVNWLLQWAAGGPNEPLWFGLDAWRWMFLAMALPAVLYGVLAFTI
MAB_0692c|M.abscessus_ATCC_199 IFLSLTIDWLLAHLAGSSRDELWLGLPAWRWMFLAMALPALVYGTLAFTI
MSMEG_2966|M.smegmatis_MC2_155 AAAAAGVGWALSTMGP----------DAWRWMLASPAVFGVVTLMLRAGT
TH_3722|M.thermoresistible__bu FLLGSVTVTALQVALP----DQVMTDVGWRIPFLLAGPLGLIGLYIRLRL
. * ** : . . . :
MMAR_2574|M.marinum_M PESPRWLFIHGREQEAEQIVREIEEEVERDTGQRLPDPPGRPLKIRQRQR
MUL_3187|M.ulcerans_Agy99 PESPRWLFIHGREQEAEQIVREIEEEVERDTGQRLPDPPGRPLKIRQRQR
MAV_3053|M.avium_104 PESPRWLFIHGREEEAEHIVGEIEEAVQQQTGRPLPEPQGKALRIRQRTA
Mb3364|M.bovis_AF2122/97 PDTARWYLLKGRIADARSALRRIQPEAD------IDAELADMAAAVDERG
Rv3331|M.tuberculosis_H37Rv PDTARWYLLKGRIADARSALRRIQPEAD------IDAELADMAAAVDERG
Mflv_3055|M.gilvum_PYR-GCK PESPRYLVATHKIPEARRVLSMLLGQKN------LEITITRIRETLERED
Mvan_3472|M.vanbaalenii_PYR-1 PESPRYLVASHKIPEARRVLSMLLGKKN------LEITITRIRETLERED
MAB_0692c|M.abscessus_ATCC_199 PESPRYLVATHRIPEARTVLATLLGEKN------LDITIGRIQETLDQST
MSMEG_2966|M.smegmatis_MC2_155 PESPRWLLSRGRTEEAQRVCRKVWGNDA---------------DIAMIPA
TH_3722|M.thermoresistible__bu DDTPAFTALSEQEEVAQSPLREAVQTAW----------------------
::. : : *.
MMAR_2574|M.marinum_M ISLWEIARVAFTRYPRRAFLGLALFIGQAFLYNGVTFNLGTLLSGFYGVE
MUL_3187|M.ulcerans_Agy99 ISLWEIARVAFTRYPRRAFLGLALFIGQAFLYNGVTFNLGTLLSGFYGVE
MAV_3053|M.avium_104 ISFREIAAVAFKLYPRRAVLGLALFIGQAFLYNGVTFNLGTLLSQFYAVP
Mb3364|M.bovis_AF2122/97 GGIGEMVRRP---YLRATLFVIALGFLVQITGINAIIYYSPRLFAAMGFA
Rv3331|M.tuberculosis_H37Rv GGIGEMVRRP---YLRATLFVIALGFLVQITGINAIIYYSPRLFAAMGFA
Mflv_3055|M.gilvum_PYR-GCK RPSWRDLKKPTGGIYGIVWVGLGLSIFQQFVGINVIFYYSNVLWQAVGFS
Mvan_3472|M.vanbaalenii_PYR-1 KPSWRDMRKPTGGLYGIVWVGLGLSIFQQFVGINVIFYYSNVLWQAVGFS
MAB_0692c|M.abscessus_ATCC_199 APSWRDLRKPTGGLHAIVWIGVALAVFQQLVGINVIFYYSNVLWQAVGFG
MSMEG_2966|M.smegmatis_MC2_155 EPAHTPFTALFRGIYLRRVVFVGVFFTAHVIPLFAVYTFGPDILREMGVG
TH_3722|M.thermoresistible__bu ---------------RSILQVIGLMIIFNVAYYVVFAYMPTYLIKELGLS
:.: . . . : ..
MMAR_2574|M.marinum_M ---SGHVPLFFIVWALSNFVGPLVLGRLFDTVGRKPMITMSYIGSAVIAV
MUL_3187|M.ulcerans_Agy99 ---SGHVPLFFIVWALSNFVGPLVLGRLFDTVGRKPMITMSYIGSAVIAV
MAV_3053|M.avium_104 ---SGMVPVFFVLWALSNFAGPLLLGHLFDTVGRKQMITLTYIGSAVVVV
Mb3364|M.bovis_AF2122/97 G--YFAMLALPAMVQVAGLAAVCASLFLVDRLGRRPILLSGIATMITADA
Rv3331|M.tuberculosis_H37Rv G--YFAMLALPAMVQVAGLAAVCASLFLVDRLGRRPILLSGIATMITADA
Mflv_3055|M.gilvum_PYR-GCK ---ADESAVYTVITSVVNVLTTLIAIALIDKIGRKPLLLIGSVGMAVTLS
Mvan_3472|M.vanbaalenii_PYR-1 ---ADESAVYTVITSVINVLTTLIAIALIDKIGRKPLLLIGSSGMAVTLI
MAB_0692c|M.abscessus_ATCC_199 ---ESSSFTITVITSITNIATTLVAIALIDRVGRKPLLLIGSAGMAATLG
MSMEG_2966|M.smegmatis_MC2_155 AHGSHHVYVAELVISLLFLVGGVPGLLLVDRIGRKPLLLWTFAVMSAAFI
TH_3722|M.thermoresistible__bu ---SSDAFISSTIACVVALVLILPLAALSDRIGRKPLLVGGAIAFAVLAY
: : . * * :**: :: .
MMAR_2574|M.marinum_M VLAVIFVN----------------QTGGVWTFIIVLAAAFFLASAGASAA
MUL_3187|M.ulcerans_Agy99 VLAVIFVN----------------QTGGVWTFIIVLAAAFFLASAGASAA
MAV_3053|M.avium_104 ALALVFLT----------------QAGGVWAFIGVLIVAFFLASAGASAA
Mb3364|M.bovis_AF2122/97 VLITVFANDSDG------------GTGLVLGFAGVLLFIIGFNFGFGSLV
Rv3331|M.tuberculosis_H37Rv VLITVFANDSDG------------GTGLVLGFAGVLLFIIGFNFGFGSLV
Mflv_3055|M.gilvum_PYR-GCK TMAFIFANAELIENEAGEMVPSLPGASGVIALIAANLFVVAFGMSWGPVV
Mvan_3472|M.vanbaalenii_PYR-1 TMAVIFANATVGADGN----PSLPGASGVIALIAANLFVVAFGMSWGPVV
MAB_0692c|M.abscessus_ATCC_199 TMAVIFGSATMVDGKP-----HLGPVAGPVALVAANLFVVAFGMSWGPVV
MSMEG_2966|M.smegmatis_MC2_155 AMAVVPGAP-------------------AQILFALLALYAVTSGACNFIE
TH_3722|M.thermoresistible__bu PLFLLLNS------------------GSTAAAMIAHAGLAAIESVVISVA
: :
MMAR_2574|M.marinum_M YLTVSEIFPMETRALAIAFFYAVGTAIGGISGPLLFGQLIESGQRSQVFW
MUL_3187|M.ulcerans_Agy99 YLTVSEIFPMETRALAIAFFYAVGTAIGGISGPLLFGQLIESGQRSQVFW
MAV_3053|M.avium_104 YLTVSEIFPMETRALAIAFFYAMGTAIGGITGPLLFGQLIDSGQRDHVVW
Mb3364|M.bovis_AF2122/97 WVYAAESFPSRLRSMGSSLMLTSTLTANAIVAAFSLTMLRVLGGA----G
Rv3331|M.tuberculosis_H37Rv WVYAAESFPSRLRSMGSSPMLTSTLTANAIVAAFSLTMLRVLGGA----G
Mflv_3055|M.gilvum_PYR-GCK WVLLGEMFPNRIRAAALGLAAAGQWTANWVITVSFPELRNFLG------A
Mvan_3472|M.vanbaalenii_PYR-1 WVLLGEMFPNRIRAAALGLAAAGQWAANWLITVTFPGLREHLG------L
MAB_0692c|M.abscessus_ATCC_199 WVLLGEIFPNRIRAAAMGLATAGNWAANWAVTVTFPALRDALG------I
MSMEG_2966|M.smegmatis_MC2_155 IIYPNELFPTSVRASATGTVVAISRVGSAVSTFVLPLVLSGTGLG----G
TH_3722|M.thermoresistible__bu VVTAVEQFTTRVRYSGMSVGYNVCVALFGGTTPYVMTWLIDTTAN---PL
: * *. * . . .
MMAR_2574|M.marinum_M SFIIGAAVMAVAGLVELWLGIAAEQRPLEELALPLTVADAEDDDEPADGA
MUL_3187|M.ulcerans_Agy99 SFIIGAAVMAVAGLVELWLGIAAEQRPLEELALPLTVVDAEDDDEPADGA
MAV_3053|M.avium_104 SFLIGAVVMAAAGLVELWLGIAAEQRPLEDLALPLTVDDAEDTEPQGDSA
Mb3364|M.bovis_AF2122/97 VFAVFGTFAVVAFVVVYRFAPETKGRKLEEIRHFWENGGRWPAERSPAAD
Rv3331|M.tuberculosis_H37Rv VFAVFGTFAVVAFVVVYRFAPETKGRKLEEIRHFWENGGRWPAERSPAAD
Mflv_3055|M.gilvum_PYR-GCK AYGFYALCAVLSGLFVWKWVRETKGVSLEDMHGEILHGDKSATG------
Mvan_3472|M.vanbaalenii_PYR-1 AYGFYGLCAVLSGLFVWRWVMETKGVSLEDMHGEILHADKTATG------
MAB_0692c|M.abscessus_ATCC_199 AYGCYALCAVLSLLFVARWVEETKGRALEDMDSAIS--------------
MSMEG_2966|M.smegmatis_MC2_155 VMWLLAGVNVVGLLVTLVLGEETRGRALSETSAATRLTEPETRSDPVDA-
TH_3722|M.thermoresistible__bu APACAVTLAAVVSLGVVMTLRETAARPLAGTP------------------
. : : *
MMAR_2574|M.marinum_M GARGAQHPGS
MUL_3187|M.ulcerans_Agy99 GARGAQHPGS
MAV_3053|M.avium_104 PVD-------
Mb3364|M.bovis_AF2122/97 EP--------
Rv3331|M.tuberculosis_H37Rv EP--------
Mflv_3055|M.gilvum_PYR-GCK ----------
Mvan_3472|M.vanbaalenii_PYR-1 ----------
MAB_0692c|M.abscessus_ATCC_199 ----------
MSMEG_2966|M.smegmatis_MC2_155 ----------
TH_3722|M.thermoresistible__bu ----------