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MPRWEHGSEDRLKQAATELFEERGFQNTTAVEIAKRARVTTRTFFRYFADKQAVVFADAERLRAALIQQL GNTADAGQPLRSVTAVLAGFDWESLGSRESQRRRDRMIASNPELLERDLMKQHEMAEAFSGVLRERGVEP YAAELAARVGIDVFRTAYRRWLAADEGDAELSALVEAVMTALNSIAPAPRGSET
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6862 | - | - | 100% (194) | putative transcription regulator |
| M. smegmatis MC2 155 | MSMEG_3469 | - | 3e-28 | 36.98% (192) | TetR family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4033 | - | 8e-09 | 24.86% (173) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0710c | - | 4e-09 | 26.62% (154) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_5062 | - | 7e-08 | 27.87% (183) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0691c | - | 4e-09 | 26.62% (154) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3837 | - | 9e-10 | 26.54% (162) | transcriptional regulatory protein TetR |
| M. marinum M | MMAR_2812 | - | 5e-11 | 28.87% (142) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0586 | - | 7e-24 | 38.50% (187) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1899 | - | 1e-09 | 28.65% (185) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_2933 | - | 6e-11 | 28.17% (142) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1927 | - | 2e-31 | 40.54% (185) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5062|M.gilvum_PYR-GCK -----MSAARPRVGRRRSTSWEHISDVAIDLFMARGFDDVSVDDVASAAG
TH_1899|M.thermoresistible__bu --------------------------VALDLFADRGFDEVSVDDVAAAAG
MAB_3837|M.abscessus_ATCC_1997 -----MNAQPARVGRRPSTTRDEITAVAMTLFAQHGFDEVSVDDIAAAAG
Mb0710c|M.bovis_AF2122/97 ------MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAG
Rv0691c|M.tuberculosis_H37Rv ------MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAG
MMAR_2812|M.marinum_M -----MTVPTNRHELRRRSTHEALRRAALKSFACKGFAQVTVTELAREAG
MUL_2933|M.ulcerans_Agy99 -----MTVPTNRHELRRRSTHEALRRAALKSFARKGFAQVTVTELAREAG
MAV_0586|M.avium_104 ------------MARWEPDARARLVAAALDLFNERGYDQTTVAEIAERAG
Mvan_1927|M.vanbaalenii_PYR-1 MSAAVIPGYDRRMSRWQPNARERLEQAALELYTRQGFDQTTVDDIAQRAG
MSMEG_6862|M.smegmatis_MC2_155 ------------MPRWEHGSEDRLKQAATELFEERGFQNTTAVEIAKRAR
.* : :*: :.:. ::* *
Mflv_5062|M.gilvum_PYR-GCK IARRTLFRYYPSKSALPWGDFDAHLDHMRALLADLDPEVPIRDALRTALL
TH_1899|M.thermoresistible__bu IGRRTLFRYYPSKNAIPWGDFDAHLDRMRDLLDGIGPDVPIGAALRSMLL
MAB_3837|M.abscessus_ATCC_1997 IARRTVFRYYSSKNAIVWGDFDSHLGVMRALLDETADTVDTSTALRQAVL
Mb0710c|M.bovis_AF2122/97 IARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALL
Rv0691c|M.tuberculosis_H37Rv IARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALL
MMAR_2812|M.marinum_M VTERTFFRHFPTKEAVLFQDYENQLEWLAQALAQRPVSEPLFDAVLASVA
MUL_2933|M.ulcerans_Agy99 VTERTFFRHFPTKEAVLFQDYENQLEWLARALAQRPVSEPLFDAVLASVA
MAV_0586|M.avium_104 LTKSTFFRHFPDKRDVLAAGQDAIAQLLREGIAAAPADATPLALVCSGLK
Mvan_1927|M.vanbaalenii_PYR-1 LTERTFFRHFADKREVLFSGQAALIDLVTASVAAQEDTDPPLDVVAAALT
MSMEG_6862|M.smegmatis_MC2_155 VTTRTFFRYFADKQAVVFADAERLRAALIQQLGNTADAGQPLRSVTAVLA
: *.**::. * : . : : : :
Mflv_5062|M.gilvum_PYR-GCK AFNDF--DDPDRHRQRMRLILETE-ALQAYSMTMYAGWRAVVAAFVADR-
TH_1899|M.thermoresistible__bu AFNDFGEDETGRHRRRMRVILQTD-ALQAHSMTMYAGWRAVVADFVARR-
MAB_3837|M.abscessus_ATCC_1997 TFNDFPVDETPRHRMRMRMILEVP-ALQAYSMLMYTGWRDVIAQFVARR-
Mb0710c|M.bovis_AF2122/97 AFNTFDESETIRHRKRMRVILQTP-ELQAYSMTMYAGWREVIAKFVARR-
Rv0691c|M.tuberculosis_H37Rv AFNTFDESETIRHRKRMRVILQTP-ELQAYSMTMYAGWREVIAKFVARR-
MMAR_2812|M.marinum_M AFPHDLEVVRQAATARS-ELISAD-RIANHLRVVQSSFAQVLTAFVRDRY
MUL_2933|M.ulcerans_Agy99 AFPHDLEVVRQAATARS-ELISAD-RIANHLRVVQSSFAQVLTAFVRNRY
MAV_0586|M.avium_104 SAAAAFTPFNKELAPRLRAAIAASAELQERNALKQIGLALAVSEALQAR-
Mvan_1927|M.vanbaalenii_PYR-1 AAGSALDGR-GDRARQRQAVIDANPGLRERELIKLATLADTLAEALRQR-
MSMEG_6862|M.smegmatis_MC2_155 GFDWESLGS-RESQRRRDRMIASNPELLERDLMKQHEMAEAFSGVLRER-
: : : ..: : *
Mflv_5062|M.gilvum_PYR-GCK LGVGGDDLRPQTVAWTMLAVSLSAYEHWLA-DET-ACLQSSLGEAFDLLA
TH_1899|M.thermoresistible__bu LGLAPSDLVPQTVAWTMLGVALSAYAYWLA-DES-VPLAQALADAFDAIR
MAB_3837|M.abscessus_ATCC_1997 SGTDPGSLLPQTVAWTLLGVALAAYEQWLA-DES-SKLTTLLGKGFDAAE
Mb0710c|M.bovis_AF2122/97 SGGKTTDFMPQTVAWTMLGVALSAYEHWLR-DES-VSLTEALGAAFDVVG
Rv0691c|M.tuberculosis_H37Rv SGGKTTDFMPQTVAWTMLGVALSAYEHWLR-DES-VSLTEALGAAFDVVG
MMAR_2812|M.marinum_M ADVANVDLVAEVAGATIAAALVVAVENWGRNGCA-VDLGELVAASLDLVR
MUL_2933|M.ulcerans_Agy99 ADVANVDLVAEVAGATIAAALVVAVENWGRYGCA-EDLGELVAASLDLVR
MAV_0586|M.avium_104 ---GVPEPAAALAAELGALAFKTAYARWAEPDES-GDLGDMACQALRELH
Mvan_1927|M.vanbaalenii_PYR-1 ---GVEAPAARLAAEVGLAVFRVAFERWVQSPGG-APLPTLIAAAFADLR
MSMEG_6862|M.smegmatis_MC2_155 ---GVEPYAAELAARVGIDVFRTAYRRWLAADEGDAELSALVEAVMTALN
. .. . * * * :
Mflv_5062|M.gilvum_PYR-GCK SGLSGLESGVSEFAPGARR
TH_1899|M.thermoresistible__bu PGLDALDG--KKFA-----
MAB_3837|M.abscessus_ATCC_1997 VGLRALR------------
Mb0710c|M.bovis_AF2122/97 AGLDRLNQ-----------
Rv0691c|M.tuberculosis_H37Rv AGLDRLNQ-----------
MMAR_2812|M.marinum_M SGLAPLS------------
MUL_2933|M.ulcerans_Agy99 SGLAPLS------------
MAV_0586|M.avium_104 AAAADLG------------
Mvan_1927|M.vanbaalenii_PYR-1 RIVA---------------
MSMEG_6862|M.smegmatis_MC2_155 SIAPAPRGSET--------