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M. smegmatis MC2 155 MSMEG_3448 (-)

annotation: two-component system sensor kinase
coordinates: 3516234 - 3517415
length: 393

DPRKSGAVTMADRRRNLRELVETQAALRRLAVLIARDTPPSDVFTAVTGEVRRRYGAATARMVRFESDGT
ATMVANVGTIGPHVRVGGPWTGYPECGLTQKVWNTGRSARVDDYREVPGGEPYVSEGLVSGVAVPIYVAG
RLWGFIAIGSVTGPLPADVERCLAEFTGLTATAIATAQSRAEIRASRTRIVAAFDNARKRLERDLHDGAQ
QHLVSLALRVAMLSDCPGVSDSIRNQLKELSIGLDTVIGDLRELARGIHPAILSQAGLEPALRALAARSV
LPVELRLGVPDRLPTSIESGAYYIAAEALANATKHAHATRVRIEAELGGAMLRVAVIDDGIGGADVRSGT
GLLGLHDRAEALGGRLSVLSPTGGGTHIQFDIDCAATNVCCG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3448--100% (393)two-component system sensor kinase
M. smegmatis MC2 155MSMEG_2248-2e-7545.23% (367) two-component system sensor kinase
M. smegmatis MC2 155MSMEG_0980-1e-7344.96% (367) signal transduction histidine kinase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3156cdevS2e-1324.93% (377) two component sensor histidine kinase DEVS
M. gilvum PYR-GCKMflv_0967-3e-2934.94% (249) integral membrane sensor signal transduction histidine kinase
M. tuberculosis H37RvRv3132cdevS7e-1324.67% (377) two component sensor histidine kinase DEVS
M. leprae Br4923MLBr_02124-2e-0627.75% (227) sensor histidine kinase
M. abscessus ATCC 19977MAB_4499-1e-6340.00% (375) putative two-component system sensor kinase
M. marinum MMMAR_3479-3e-1626.48% (287) two-component sensor histidine kinase
M. avium 104MAV_4108-5e-1324.84% (310) GAF family protein
M. thermoresistible (build 8)TH_1533-2e-2835.98% (214) two-component system sensor kinase
M. ulcerans Agy99MUL_2422devS1e-1123.16% (367) two component sensor histidine kinase DevS
M. vanbaalenii PYR-1Mvan_2071-6e-7242.16% (389) multi-sensor signal transduction histidine kinase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3156c|M.bovis_AF2122/97           -----------------MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVE
Rv3132c|M.tuberculosis_H37Rv        -----------------MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVE
MUL_2422|M.ulcerans_Agy99           ----------MTDEPHPQDAGPSLGVPSGDGLRPLRLTLSQLRLRELLVE
MMAR_3479|M.marinum_M               --------------------------------------------------
MAV_4108|M.avium_104                -------------------------------------------------M
MSMEG_3448|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_2071|M.vanbaalenii_PYR-1       -----------------MPTRFLERVVRSPARPLGLGIAVAAGFLAAEVL
MAB_4499|M.abscessus_ATCC_1997      MQQAAQASSPRPILMPDYISGWRTQLFGSTPPSARLGIVAAVVLLVAESM
Mflv_0967|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1533|M.thermoresistible__bu      ----------------------------------------MVAVTAETAP
MLBr_02124|M.leprae_Br4923          ------------------------------------MNILSRIFARTPSL
                                                                                      

Mb3156c|M.bovis_AF2122/97           VQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARY
Rv3132c|M.tuberculosis_H37Rv        VQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARY
MUL_2422|M.ulcerans_Agy99           VQERVEQIVEGRDRLDGLVEAMLVVTSGLELDATLRTIVHSATNLVDARY
MMAR_3479|M.marinum_M               MHAQLDELLAARDQMEQLLRVIVEIGSDLDLDATLRRIVLAARELTSAPY
MAV_4108|M.avium_104                TGNRFDELAAARDQTEKLLRVIAEIGAGLDLDATLHRIISAARELTSAPY
MSMEG_3448|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_2071|M.vanbaalenii_PYR-1       AVFALKKIAPENAFGALLLLGVLVVSAGWGFGLSIATSLASAAVYAYLHL
MAB_4499|M.abscessus_ATCC_1997      LTIFLRTIAPTEHLAAVYLIGILVISVIWRLRLALAMSIASAIVFDCIRN
Mflv_0967|M.gilvum_PYR-GCK          ----MMVQAPARTLVAAMISGPRYLVSMWPWRALLWTVFGGVLGTVLIVG
TH_1533|M.thermoresistible__bu      APAPTRTARLGVVPTASMVTGAAIALVWFWIPLTILIVGISSIPSVIG--
MLBr_02124|M.leprae_Br4923          RTRVVVATAIGAAIPVLIVGTVVWVGITNDRKERLDRKLDEAAGFAIPFV
                                                                                      

Mb3156c|M.bovis_AF2122/97           GAMEVHDR------------------------------------------
Rv3132c|M.tuberculosis_H37Rv        GAMEVHDR------------------------------------------
MUL_2422|M.ulcerans_Agy99           CALEVHDR------------------------------------------
MMAR_3479|M.marinum_M               GALAVRDP------------------------------------------
MAV_4108|M.avium_104                GALAVRDW------------------------------------------
MSMEG_3448|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_2071|M.vanbaalenii_PYR-1       EGRDSLAPALIIFLTLALLTNALVGQARLRAAEAEQRRREADLSADLARV
MAB_4499|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_0967|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1533|M.thermoresistible__bu      --------------------------------------------------
MLBr_02124|M.leprae_Br4923          PRGLDEIP------------------------------------------
                                                                                      

Mb3156c|M.bovis_AF2122/97           -------------------------------------------------Q
Rv3132c|M.tuberculosis_H37Rv        -------------------------------------------------Q
MUL_2422|M.ulcerans_Agy99           -------------------------------------------------D
MMAR_3479|M.marinum_M               -------------------------------------------------E
MAV_4108|M.avium_104                -------------------------------------------------H
MSMEG_3448|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_2071|M.vanbaalenii_PYR-1       MLRAPALGPALEDAGRRFADVLGLPYATLTVGGGATGADEMAIDLVDGAE
MAB_4499|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_0967|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1533|M.thermoresistible__bu      --------------------------------------------------
MLBr_02124|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3156c|M.bovis_AF2122/97           HRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPAS
Rv3132c|M.tuberculosis_H37Rv        HRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPAS
MUL_2422|M.ulcerans_Agy99           KRVLQFVYEGIDEDTVARIGHLPEGLGIIGLLIDEPKPLRLEDISQHPAS
MMAR_3479|M.marinum_M               GTLIRFIHAGMDDDVARRIGHLPVGKGVLGVSLVETPALRLDDLTMHPAA
MAV_4108|M.avium_104                ANLISFVHEGMDAETVRRIGHHPVGKGLLSLSLLDTPALRMDDLTAHPAA
MSMEG_3448|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_2071|M.vanbaalenii_PYR-1       HTGTLLVPRDLPLASVRRIHRMVPSLQALLAAACDREDITAELEASRREL
MAB_4499|M.abscessus_ATCC_1997      ------WPKANPLSTES--HNLITHLSFLAVT------------------
Mflv_0967|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1533|M.thermoresistible__bu      --------------------------------------------------
MLBr_02124|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3156c|M.bovis_AF2122/97           IGFP----------------------------------------------
Rv3132c|M.tuberculosis_H37Rv        IGFP----------------------------------------------
MUL_2422|M.ulcerans_Agy99           IGFP----------------------------------------------
MMAR_3479|M.marinum_M               CGFP----------------------------------------------
MAV_4108|M.avium_104                AGFP----------------------------------------------
MSMEG_3448|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_2071|M.vanbaalenii_PYR-1       ERFFAVASDLLFIGTYVDGVAQLTRVNPAFERALGYSAAELAARPLTEFI
MAB_4499|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_0967|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1533|M.thermoresistible__bu      --------------------------------------------------
MLBr_02124|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3156c|M.bovis_AF2122/97           ---PYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALA
Rv3132c|M.tuberculosis_H37Rv        ---PYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALA
MUL_2422|M.ulcerans_Agy99           ---SHHPPMRTFLGVPVRVRDVSLGTLYLTDKTNGQPFSDDDELLVQALA
MMAR_3479|M.marinum_M               ---EHHPPMRAFLAVPITIRGTVFGSLYLTHVDPGRKFSESDEFAARALA
MAV_4108|M.avium_104                ---EHHPAMRAFLAVPITIRGAVFGNLYLTHVDEARVFSDADEMAARALA
MSMEG_3448|M.smegmatis_MC2_155      -----------MD--PRKSGAVTMADR--RRN------------------
Mvan_2071|M.vanbaalenii_PYR-1       HPDDRDGTAAALDSVPQTDGATQFENRSLRRDGGVRWLEWNVVSDRGVLL
MAB_4499|M.abscessus_ATCC_1997      -------LTASALAALARAGTIEAERR--RRE------------------
Mflv_0967|M.gilvum_PYR-GCK          ------LPLILVMGVSRSARTAVWAPL-----------------------
TH_1533|M.thermoresistible__bu      -------FLLAGVVFIYLIRGVEWVER-----------------------
MLBr_02124|M.leprae_Br4923          -----RSPNDQDAIITVRRGNLVKSN------------------------
                                                                                      

Mb3156c|M.bovis_AF2122/97           AAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEP-ATVFRLVAAE
Rv3132c|M.tuberculosis_H37Rv        AAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEP-ATVFRLVAAE
MUL_2422|M.ulcerans_Agy99           AAAGIAIANARLYEQAKARQAWIGATRDIATELLSGTEP-ASVFRLVAEE
MMAR_3479|M.marinum_M               FAAGVAIDNAQVFERERTAVKWMEASREITTALMSSTESRREPLQLIAQR
MAV_4108|M.avium_104                FAAAVAIDNAQVFERERMSVKWIEASREITTALLSRTEPHRRPMQLIAER
MSMEG_3448|M.smegmatis_MC2_155      ---------------LRELVETQAALRRLAVLIARDTPPSDVFTAVTGEV
Mvan_2071|M.vanbaalenii_PYR-1       GGARDVTERRREQDRLRMARTQQAALRRVATLVARGAPLSEVYDVAVTEL
MAB_4499|M.abscessus_ATCC_1997      ---------------AAAIAQQQAALRRTATLVASNVSPVELYAKVVEEA
Mflv_0967|M.gilvum_PYR-GCK          -------------------LEIECARLSLIDEAAAERARSDVNAARAQQR
TH_1533|M.thermoresistible__bu      -------------------IRSEAVFGMGIPIPPRRLSPHTGFQRWAHQL
MLBr_02124|M.leprae_Br4923          -----------------FDITLPKLTNDYADTYLRGVRYRVRTVEIPAPE
                                                                                      

Mb3156c|M.bovis_AF2122/97           ALKLTAADAALVAVPVDEDMPAA-DVGELLVIETVGSAVASTVGRTIPVA
Rv3132c|M.tuberculosis_H37Rv        ALKLTAADAALVAVPVDEDMPAA-DVGELLVIETVGSAVASIVGRTIPVA
MUL_2422|M.ulcerans_Agy99           ALKLTSADAALVAIPVDEDVPAS-EVAQLLVIETVGNAVAAAEGCTIAVA
MMAR_3479|M.marinum_M               ACTLTDAEQAIVLVPVESDLATD-EIDTLVVSAAVGLHAEEVVGQQVPVR
MAV_4108|M.avium_104                ACALTDAEQAIVLVPADPEQPGNPEVDTLVVSAAVGLPAADVLGQRVPVR
MSMEG_3448|M.smegmatis_MC2_155      RRRYGAATARMVRFESDGT-------ATMVANVGTIGPHVRVGGPWTGYP
Mvan_2071|M.vanbaalenii_PYR-1       AHSLGVNHVTLLAFEADDH-------AVVRAALKSAHQPGFAVGDRLSLD
MAB_4499|M.abscessus_ATCC_1997      ARCFASPTAVLVQLMPGDE-------GTIVAGHGTEESRTPPAGKRFPLL
Mflv_0967|M.gilvum_PYR-GCK          LPTLRQAGYMVLTAMFTGP------WGVVLVGFSAILIGVMVAAPWLVRP
TH_1533|M.thermoresistible__bu      WLDISSARFWKAAAH-----------HYLRMSYDMLAVGVAFALLAFAFL
MLBr_02124|M.leprae_Br4923          PTSIAVGATYDATVAETNN-----LHRRVLLICGFAIAAAAVFAWLLAAF
                                                                :                     

Mb3156c|M.bovis_AF2122/97           G-AVLREVFVNGIPRRVDRVDLEG---LDELADAG--PALLLPLRARGTV
Rv3132c|M.tuberculosis_H37Rv        G-AVLREVFVNGIPRRVDRVDLEG---LDELADAG--PALLLPLRARGTV
MUL_2422|M.ulcerans_Agy99           G-TALAEVLLDSAPRQVDKIAVED---VDELGDMG--PALVLPLRATDAV
MMAR_3479|M.marinum_M               G-STCGDVFRSGEPLISEAFSYP----IEAFTDVAQRSAIVMPLSAHEKV
MAV_4108|M.avium_104                G-STSGAVFKSGEPLITDEFRYP----IQAFTDAGRRPAIVMPLRARDEV
MSMEG_3448|M.smegmatis_MC2_155      ECGLTQKVWNTGRSARVDDYREVPG--GEPYVSEGLVSGVAVPIYVAGRL
Mvan_2071|M.vanbaalenii_PYR-1       GGSISEQVHRTGLPARIDDYSEVPGRIATRLRELGIRSAAGSPLTVDGGT
MAB_4499|M.abscessus_ATCC_1997      D---SNNVAR----------------------ELRLTPAVCAPIVVDAKH
Mflv_0967|M.gilvum_PYR-GCK          GEPINVGLWLID--------------------------SSGEAWAAVTLG
TH_1533|M.thermoresistible__bu      GPAGAIAVRNSDDN-----------------------AGLTFLPPALAVV
MLBr_02124|M.leprae_Br4923          AVRPFKQLAQQTRS---------------------VDAGGEAPRVEVHGA
                                           :                              .           

Mb3156c|M.bovis_AF2122/97           AGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMRELDVLT
Rv3132c|M.tuberculosis_H37Rv        AGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMRELDVLT
MUL_2422|M.ulcerans_Agy99           AGVVVLLHPSSPESVTEEQLEMMAAFADQAALALQLATSQRRMRELDVVT
MMAR_3479|M.marinum_M               AGVIAVARGADQPPFDARCLDLVSQFATHAAIALLLASGREDARQLTILA
MAV_4108|M.avium_104                VGVIAIARGTEQPPFDESYLDLVRDFATHAAIALVLAAAREDARQLAVLA
MSMEG_3448|M.smegmatis_MC2_155      WGFIAIG-SVTGP-LPADVERCLAEFTGLTATAIATAQSRAEIRASRTRI
Mvan_2071|M.vanbaalenii_PYR-1       RGVLVVG-SHAVQGVPDGTEAHIGDFADLISTAIANAETRAELTASRARI
MAB_4499|M.abscessus_ATCC_1997      WGTLIVG-SHTPAQRDQDIRAGVRDFADLVATAIANAATREELAASRARI
Mflv_0967|M.gilvum_PYR-GCK          IALLVLAAYLVGAYAAAVAQITVAALVDPHALQREVARLEHSRTALLDAV
TH_1533|M.thermoresistible__bu      LAVIAVAAAAAILFFAPAVDARIDRWLLPPSSTEALQHQVSALSDARAGA
MLBr_02124|M.leprae_Br4923          TEAVEIAEAMRGMLQRIWNEQNRTKEALASARDFAAVSSHELRTPLTAMR
                                       : :                        :                   

Mb3156c|M.bovis_AF2122/97           D------RDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE--VQQRLSD
Rv3132c|M.tuberculosis_H37Rv        D------RDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE--VQQRLSD
MUL_2422|M.ulcerans_Agy99           E------RDRIARDLHDHVIQRLFAIGLALQGSVPRTREPK--VQQRLSE
MMAR_3479|M.marinum_M               E------RERIAHDLHDHVIQRLFASGMDLQGTLARARSPE--VIDRLNR
MAV_4108|M.avium_104                E------RERIAHDLHDHVIQRLFAAGMDLQGTLARARSPE--VADRLNR
MSMEG_3448|M.smegmatis_MC2_155      VAAFDNARKRLERDLHDGAQQHLVSLALRVAMLSDCPGVSD-SIRNQLKE
Mvan_2071|M.vanbaalenii_PYR-1       VAAADEARRGFERDLHDGAQQRIVSLSLQLREAEAAVEGDE-ALRTQLST
MAB_4499|M.abscessus_ATCC_1997      VSASDTARRRLERDLHDGAQQRLAYLRLKLGMVRAAVPATDAELTQELNN
Mflv_0967|M.gilvum_PYR-GCK          E----QERRRIESDLHDRVQHRLVALALTLGIAENAHGDSA--AGRLAAD
TH_1533|M.thermoresistible__bu      VSSAQTERHRIERDLHDSVQPRLVSLAMTIGLAQTKLDTDLPAAKKLIAE
MLBr_02124|M.leprae_Br4923          TNLEVLATLDLADDQRKEVLGDVIRTQSRIEATLSALERLA---QGELST
                                              :  * :. .   :      :                    

Mb3156c|M.bovis_AF2122/97           VVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADS-GLRTSV
Rv3132c|M.tuberculosis_H37Rv        VVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADS-GLRTSV
MUL_2422|M.ulcerans_Agy99           VIDDLQGVIQEIRTTIFDLHGSSQGVTRLRQRIDAAVAAFGSS-GLRTTV
MMAR_3479|M.marinum_M               TVDDLQTIIEEIRSTIFQLKSPSGRDGGFRQRIQQVVADLTEHRDVVTTI
MAV_4108|M.avium_104                TLDDLQTIIEEIRTTIFALRSPAAVAGDFRHRIQRVIAELTENRDLVTTV
MSMEG_3448|M.smegmatis_MC2_155      LSIGLDTVIGDLRELARGIHPAILSQAGLEPALRALAARSVLPVELRLGV
Mvan_2071|M.vanbaalenii_PYR-1       VVNGLAGLHSDLQELSRGLHPAVLSRGGLKPAMRNLARRSTVPVELTVDI
MAB_4499|M.abscessus_ATCC_1997      LDTDLTAVTRELQEFSRGLHPAILSKG-LAPALRTLARRSLIPVRTELEL
Mflv_0967|M.gilvum_PYR-GCK          AHGQVDDIAAELRSVLLGILPRALTEHGLVAAATDLIGRYPVAVEADFGA
TH_1533|M.thermoresistible__bu      AHEDAKSALAELRDVVRGIAPTILTDRGLDAALSAVVQRAETSGVPTTLN
MLBr_02124|M.leprae_Br4923          SDDHVPVDITELLDRAAHDATRSYPELKVSLVPSPTCIIVGLPAGLRLAV
                                              ::                .                     

Mb3156c|M.bovis_AF2122/97           QFVGPLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKV------D
Rv3132c|M.tuberculosis_H37Rv        QFVGPLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKV------D
MUL_2422|M.ulcerans_Agy99           QFIGPLSVVDNVLADHAEAVVREAVSNAVRHAQATTLTVRVKV------D
MMAR_3479|M.marinum_M               HMHGPMSAVQGELADHAEAVATEAISNAVRHSGAGRVTLDVSV------G
MAV_4108|M.avium_104                RMDGPMTAVGAELAEHAEAVTAEAVSNAVRHSGASRLTVQIGV------A
MSMEG_3448|M.smegmatis_MC2_155      PDR-----LPTSIESGAYYIAAEALANATKHAHATRVRIEAEL-----GG
Mvan_2071|M.vanbaalenii_PYR-1       DRR-----LPEPVEVAAYYVVAESLTNVAKHAQADSVTVEIGLDDAPDGG
MAB_4499|M.abscessus_ATCC_1997      DQK-----YGESIEIAAYYVVAEALANTAKHSQASEVVIRAHE-----AD
Mflv_0967|M.gilvum_PYR-GCK          TEIP--ARLPGPVEHTAYLVLNEALTNSAKHASAGHVTITADR-----RD
TH_1533|M.thermoresistible__bu      LHLP--RRLPEEVESVAYFVVAEALTNVVKHAQASQAVVTVRLN---ETD
MLBr_02124|M.leprae_Br4923          DNAVANAVKHGGATRVQLSAVSSRAGVEIAVDDNGSGVPEDER-------
                                                          .                           

Mb3156c|M.bovis_AF2122/97           DDLCIEVTDNGRGLPDEFTG---SGLTNLRQRAEQAGGEFTLASVPGASG
Rv3132c|M.tuberculosis_H37Rv        DDLCIEVTDNGRGLPDEFTG---SGLTNLRQRAEQAGGEFTLASVPGASG
MUL_2422|M.ulcerans_Agy99           DDLCIEVSDNGRGMPKTYTS---SGLTNLRRRAQEAGGQFTIESPAAGGG
MMAR_3479|M.marinum_M               DMFSLEVVDDGCGISPDVSRR--SGLANMRSRAEKLGGTCGITTPTEG-G
MAV_4108|M.avium_104                DMFTLDVIDNGRGIAAGNTRR--SGLANMTRRAEQLGGSCEISSPPGG-G
MSMEG_3448|M.smegmatis_MC2_155      AMLRVAVIDDGIGGADVRSG---TGLLGLHDRAEALGGRLSVLSPTGG-G
Mvan_2071|M.vanbaalenii_PYR-1       TLLRLSVTDDGTGGASADGG---SGLVGLRDRVEALSGQLTVTSRPGD-G
MAB_4499|M.abscessus_ATCC_1997      DQIHITISDDGIGGAKPRKG---TGLIGLTDRVTALGGRLDVHSASGR-G
Mflv_0967|M.gilvum_PYR-GCK          GLWWLVIRDDGRGGATIQPG---RGLATLAARVEAVNGTLTVTSPAGG-P
TH_1533|M.thermoresistible__bu      NTLQVSVFDDGCGSAQISDRDNATGLRGLAERVRAAHGTFTVSSPPTG-P
MLBr_02124|M.leprae_Br4923          -QVVFERFSRGSTASHSGSG---LGLALVAQQAQLHGGTASLETSPLG-G
                                        .   . *   .         **  :  :.    *   : : .    

Mb3156c|M.bovis_AF2122/97           TVLRWSAPLSQ------
Rv3132c|M.tuberculosis_H37Rv        TVLRWSAPLSQ------
MUL_2422|M.ulcerans_Agy99           TLLRWSAPLIQ------
MMAR_3479|M.marinum_M               TRISWTVPFGDL-----
MAV_4108|M.avium_104                TRVHWTAPLLDH-----
MSMEG_3448|M.smegmatis_MC2_155      THIQFDIDCAATNVCCG
Mvan_2071|M.vanbaalenii_PYR-1       TSISATIPVD-------
MAB_4499|M.abscessus_ATCC_1997      TTMTAIIPLHQSD----
Mflv_0967|M.gilvum_PYR-GCK          TEVGMRCPV--------
TH_1533|M.thermoresistible__bu      TIVTAVLPCGS------
MLBr_02124|M.leprae_Br4923          ARLLLRISAPS------
                                    : :